Professor Claude Wischik | The University of Aberdeen

Oxidative Stress Conditions Result in Trapping of PHF-Core Tau (297–391) Intermediates
2021 - Published
Maina, M. B., Al-Hilaly, Y. K., Burra, G., Rickard, J. E., Harrington, C. R., Wischik, C. M., Serpell, L. C.
Cells, vol. 10, no. 3, 703
Contributions to Journals: Articles
- [ONLINE] DOI: https://doi.org/10.3390/cells10030703
- [OPEN ACCESS] http://aura.abdn.ac.uk/bitstreams/a40fa657-872d-40f9-907e-438d23fc9812/download
Differential compartmental processing and phosphorylation of pathogenic human tau and native mouse tau in the Line 66 model of frontotemporal dementia
2020 - Published
Lemke, N., Melis, V., Lauer, D., Magbagbeolu, M., Neumann, B., Harrington, C. R., Riedel, G., Wischik, C. M., Theuring, F., Schwab, K.
Journal of Biological Chemistry, vol. 295, no. 52, pp. 18508-18523
Contributions to Journals: Articles
- [ONLINE] http://www.jbc.org/content/early/2020/10/30/jbc.RA120.014890.abstract
- [ONLINE] DOI: https://doi.org/10.1074/jbc.RA120.014890
- [OPEN ACCESS] http://aura.abdn.ac.uk/bitstreams/1d3b8abd-011d-4410-8fc6-b164f3a5f092/download
- [ONLINE] View publication in Scopus
Adaptive neurological testing method
2020 - Published
Shiells, H. C., Morson, S., Schelter, B., Wischik, D. J., Wischik, C.
Patents: Patents
Current Progress and Future Directions for Tau-Based Fluid Biomarker Diagnostics in Alzheimer’s Disease
2020 - Published
Arastoo, M., Lofthouse, R., Penny, L., Harrington, C. R., Porter, A., Wischik, C. M., Palliyil, S.
International Journal of Molecular Sciences, vol. 21, no. 22, pp. 1-19
Contributions to Journals: Articles
- [ONLINE] DOI: https://doi.org/10.3390/ijms21228673
- [OPEN ACCESS] http://aura.abdn.ac.uk/bitstreams/997e480f-f45a-476e-9038-4e42a8e187ac/download
- [ONLINE] View publication in Scopus
Tau Filament Self-Assembly and Structure: Tau as a Therapeutic Target.
2020 - Published
Oakley, S., Maina, M. B., Marshall, K. E., Al-Hilaly, Y. K., Harrington, C. R., Wischik, C. M., Serpell, L. C.
Frontiers in Neurology, vol. 11, 590754
Contributions to Journals: Articles
- [ONLINE] DOI: https://doi.org/10.3389/fneur.2020.590754
- [OPEN ACCESS] http://aura.abdn.ac.uk/bitstreams/e55ed5c9-07a3-4b04-acf1-8b62a320679c/download
- [ONLINE] View publication in Scopus
Paired helical filament forming region of tau (297-391) influences endogenous tau protein and accumulates in acidic compartments in human neuronal cells
2020 - Published
Pollack, S. J., Trigg, J., Khanom, T., Biasetti, L., Marshall, K. E., Al-Hilaly, Y. K., Rickard, J. E., Harrington, C. R., Wischik, C. M., Serpell, L. C.
Journal of Molecular Biology, vol. 432, no. 17, pp. 4891-4907
Contributions to Journals: Articles
- [ONLINE] DOI: https://doi.org/10.1016/j.jmb.2020.05.027
- [OPEN ACCESS] http://aura.abdn.ac.uk/bitstreams/1180919d-7bb9-4ef0-b615-bcead7669252/download
- [ONLINE] View publication in Scopus
Analysis of the Relationship Between Metalloprotease-9 and Tau Protein in Alzheimer's Disease
2020 - Published
Hernandes-Alejandro, M., Montaño, S., Harrington, C. R., Wischik, C. M., Salas-Casas, A., Cortes-Reynosa, P., Pérez Salazar, E., Cazares-Apatiga, J., Apatiga-Perez, R., Ontiveros Torres, M. ?., Perry, G., Pacheco-Herrero, M., Luna-Muñoz, J.
Journal of Alzheimer's Disease, vol. 76, no. 2, pp. 553-569
Contributions to Journals: Articles
- [ONLINE] DOI: https://doi.org/10.3233/JAD-200146
- [ONLINE] View publication in Scopus
Concentration-Dependent Activity of Hydromethylthionine on Clinical Decline and Brain Atrophy in a Randomized Controlled Trial in Behavioral Variant Frontotemporal Dementia
2020 - Published
Shiells, H., Schelter, B. O., Bentham, P., Baddeley, T. C., Rubino, C. M., Ganesan, H., Hammel, J., Vuksanovic, V., Staff, R. T., Murray, A. D., Bracoud, L., Wischik, D. J., Riedel, G., Gauthier, S., Jia, J., Moebius, H. J., Hardlund, J., Kipps, C. M., Kook, K., Storey, J. M. D., Harrington, C. R., Wischik, C. M.
Journal of Alzheimer's Disease, vol. 75, no. 2, pp. 501-519
Contributions to Journals: Articles
- [ONLINE] DOI: https://doi.org/10.3233/JAD-191173
- [OPEN ACCESS] http://aura.abdn.ac.uk/bitstreams/53b6ee0c-d5be-45c3-90a0-1afea8f620c4/download
- [ONLINE] View publication in Scopus
Mechanisms of anticholinesterase interference with tau aggregation inhibitor activity in a tau-transgenic mouse model
2020 - Published
Riedel, G., Klein, J., Niewiadomska, G., Kondak, C., Schwab, K., Lauer, D., Magbagbeolu, M., Steczkowska, M., Zadrozny, M., Wydrych, M., Cranston, A., Melis, V., Santos, R. X., Theuring, F., Harrington, C. R., Wischik, C. M.
Current Alzheimer Research, vol. 17, no. 3, pp. 285-296
Contributions to Journals: Articles
- [ONLINE] DOI: https://doi.org/10.2174/1567205017666200224120926
- [OPEN ACCESS] http://aura.abdn.ac.uk/bitstreams/93bdbc3a-7cb1-4d17-a739-bf474576969a/download
- [ONLINE] View publication in Scopus
Cholinergic and inflammatory phenotypes in transgenic tau mouse models of Alzheimer’s Disease and Frontotemporal Lobar Degeneration
2020 - Published
Cranston, A. L., Wysocka, A., Steczkowska, M., Zadrozny, M., Palasz, E., Harrington, C. R., Theuring, F., Wischik, C., Riedel, G., Niewiadomska, G.
Brain Communications, vol. 2, no. 1, fcaa033
Contributions to Journals: Articles
- [ONLINE] DOI: https://doi.org/10.1093/braincomms/fcaa033
- [OPEN ACCESS] http://aura.abdn.ac.uk/bitstreams/e8bdcbaa-dd08-47da-af17-30697cf2e0ce/download

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Oxidative Stress Conditions Result in Trapping of PHF-Core Tau (297–391) Intermediates

Differential compartmental processing and phosphorylation of pathogenic human tau and native mouse tau in the Line 66 model of frontotemporal dementia

Adaptive neurological testing method

Current Progress and Future Directions for Tau-Based Fluid Biomarker Diagnostics in Alzheimer’s Disease

Tau Filament Self-Assembly and Structure: Tau as a Therapeutic Target.

Paired helical filament forming region of tau (297-391) influences endogenous tau protein and accumulates in acidic compartments in human neuronal cells

Analysis of the Relationship Between Metalloprotease-9 and Tau Protein in Alzheimer's Disease

Concentration-Dependent Activity of Hydromethylthionine on Clinical Decline and Brain Atrophy in a Randomized Controlled Trial in Behavioral Variant Frontotemporal Dementia

Mechanisms of anticholinesterase interference with tau aggregation inhibitor activity in a tau-transgenic mouse model

Cholinergic and inflammatory phenotypes in transgenic tau mouse models of Alzheimer’s Disease and Frontotemporal Lobar Degeneration

Refine

Chapters in Books, Reports and Conference Proceedings

Contributions to Conferences

Contributions to Journals

Patents

Working Papers