Professor Claude Wischik
Chair in Mental Health (Clin)
- About
-
- Email Address
- c.m.wischik@abdn.ac.uk
- Office Address
TauRx Therapeutics Ltd
1st Floor, Sir Moir Lockhead Building
395 King Street
Aberdeen
AB24 5RP
United Kingdom
- School/Department
- School of Medicine, Medical Sciences and Nutrition
- Research
-
Research Overview
Molecular Neuropathology of Alzheimer's Disease, and in particular the therapeutic intervention of tau pathology
- Publications
-
Page 4 of 12 Results 31 to 40 of 114
Dityrosine Cross-links are Present in Alzheimer's Disease-derived Tau Oligomers and Paired Helical Filaments (PHF) which Promotes the Stability of the PHF-core Tau (297–391) In Vitro
Journal of Molecular Biology, vol. 434, no. 19, 167785Contributions to Journals: Articles- [ONLINE] DOI: https://doi.org/10.1016/j.jmb.2022.167785
- [OPEN ACCESS] http://aura.abdn.ac.uk/bitstreams/0a8f0abd-6cef-4f77-98b1-76e0eabc280f/download
- [ONLINE] View publication in Scopus
Oral Tau Aggregation Inhibitor for Alzheimer’s Disease: Design, Progress and Basis for Selection of the 16 mg/day Dose in a Phase 3, Randomized, Placebo-Controlled Trial of Hydromethylthionine Mesylate
Journal of Prevention of Alzheimer's Disease, vol. 9, pp. 780-790Contributions to Journals: Articles- [ONLINE] DOI: https://doi.org/10.14283/jpad.2022.63
- [OPEN ACCESS] http://aura.abdn.ac.uk/bitstreams/4b8d981b-d1b0-43ab-bbbc-a90581c02b21/download
- [ONLINE] View publication in Scopus
Glutamatergic transmission and receptor expression in the synucleinopathy h-α-synL62 mouse model: Effects of hydromethylthionine
Cellular Signalling, vol. 97, 110386Contributions to Journals: ArticlesStructural Identification of Individual Helical Amyloid Filaments by Integration of Cryo-Electron Microscopy-Derived Maps in Comparative Morphometric Atomic Force Microscopy Image Analysis
Journal of Molecular Biology, vol. 434, no. 7, 167466Contributions to Journals: Articles- [ONLINE] DOI: https://doi.org/10.1016/j.jmb.2022.167466
- [OPEN ACCESS] http://aura.abdn.ac.uk/bitstreams/bf92d10c-6597-45ea-95e4-ac6e0c02758c/download
- [ONLINE] View publication in Scopus
HMTM-Mediated Enhancement of Brain Bioenergetics in a Mouse Tauopathy Model Is Blocked by Chronic Administration of Rivastigmine
Biomedicines, vol. 10, no. 4, 867Contributions to Journals: ArticlesCrossed cerebellar diaschisis in Alzheimer's disease
Nuclear Medicine Communications, vol. 43, no. 4, pp. 423-427Contributions to Journals: Articles- [ONLINE] DOI: https://doi.org/10.1097/MNM.0000000000001531
- [ONLINE] View publication in Scopus
Hydromethylthionine enhancement of central cholinergic signalling is blocked by rivastigmine and memantine
Journal of Neurochemistry, vol. 160, pp. 172-184Contributions to Journals: ArticlesDegeneration of basal and limbic networks is a core feature of behavioural variant frontotemporal dementia
Brain Communications, vol. 3, no. 4, fcab241Contributions to Journals: ArticlesLong-term hydromethylthionine treatment is associated with delayed clinical onset and slowing of cerebral atrophy in a pre-symptomatic P301S MAPT mutation carrier
Journal of Alzheimer's Disease, vol. 83, no. 3, pp. 1017-1023Contributions to Journals: Articles- [ONLINE] DOI: https://doi.org/10.3233/JAD-210390
- [OPEN ACCESS] http://aura.abdn.ac.uk/bitstreams/ef8b32b2-335b-468f-930e-a8e0751fbda2/download
- [ONLINE] View publication in Scopus
Proteomic analysis of hydromethylthionine in the line 66 model of frontotemporal dementia demonstrates actions on tau-dependent and tau-independent networks
Cells, vol. 10, no. 8, 2162Contributions to Journals: Articles- [ONLINE] DOI: https://doi.org/10.3390/cells10082162
- [OPEN ACCESS] http://aura.abdn.ac.uk/bitstreams/131e3534-c036-4040-a381-e552f642e322/download
- [ONLINE] View publication in Scopus