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Dr Lynda Constable

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Dr Lynda Constable
Dr Lynda Constable
Dr Lynda Constable

BSc (Hons), PhD

Senior Trial Manager

About
Email Address
l.constable@abdn.ac.uk
School/Department
School of Medicine, Medical Sciences and Nutrition

Biography

I am a Senior Trials Manager working across the portfolio of clinical trials at the Centre for Healthcare Randomised Trials (CHaRT) clinical trials unit (CTU) within the Aberdeen Centre for Evaluation (ACE, formerly Health Services Research Unit (HSRU)). 

I have worked as the lead trial manager on the CHESS, PIP, DIAMOND, CATHETER II, VUE, MASTER and ASICA trials.

I graduated with a BSc in Biosciences and Chemistry and a PhD in Cancer cell and Molecular biology. Prior to joining the unit, I worked as a Research Fellow at Aberdeen University on a range of projects with an emphasis on cancer biomarkers.

External Memberships

Member of the Executive Committee of the UK Trial Managers Network (UKTMN)

Member of the Education Committee for the Society for Clinical Trials (2013 - 2020)

Chair of the Education Committee for the Society for Clinical Trials (2018-2019)

Co-Chair of the Education Committee for the Society for Clinical Trials (2017-2018)

Chair of the Webinar Committee for the Society for Clinical Trials (2017-2018)

Member of the Board of Directors for the Society for Clinical Trials (2016)

Latest Publications

  • Clinical and cost-effectiveness of medical management versus surgery for deep infiltrating endometriosis: synopsis from the DIAMOND RCT

    Cooper, K., Constable, L., Vadiveloo, T., Matuluko, A., Kennedy, C., McCann, S., Cotton, S., Gillies, K., Bruce, R., Smith, P., MacLennan, G., Clark, T. J.
    Health Technology Assessment
    Contributions to Journals: Articles

  • Protocol for a feasibility randomized control trial of the Supporting Toddlers with a connection to autism or ADHD to develop Strong Attention, Regulation, and Thinking skills (START) programme

    Hendry, A., Nosyk, M., Hulks, V., Hudson, J., Constable, L., Charman, T., Mathers, S., Rhodes, S., Scerif, G.
    Pilot and Feasibility Studies, vol. 11, no. 1, 122
    Contributions to Journals: Articles

  • Supporting the professional development of trial managers: how can you help?

    Mitchell, E. J., Arundel, C., Babalis, D., Connolly, S., Constable, L., Goodman, K., Stylianou, L., Taylor, J., Wakefield, N., Williams, S., Wolstenhulme, F.
    Trials, vol. 26, no. 1, 436
    Contributions to Journals: Articles

  • CATHETER II, a Randomised Controlled Trial Comparing the Clinical and Cost Effectiveness of Various Washout Policies versus No Washout Policy in Preventing Catheter Associated Complications in Adults Living with Long Term Catheters

    Abdel-Fattah, M., Omar, M. I., Johnson, D., Cooper, D., Constable, L., Tripathee, S., MacLennan, S., Cotton, S., Norrie, J., MacLennan, G., Catheter II Team
    45th Congress of the Société Internationale d'Urologie
    Contributions to Conferences: Posters

  • Patients and health care professionals’ perception of weekly prophylactic catheter washout in adults living with long-term catheters: Qualitative Study of the CATHETER II Trial

    Tripathee, S., Abdel-Fattah, M., Johnson, D., Constable, L., Cotton, S., Cooper, D., MacLennan, G., Evans, S., Young, A. J., Dimitropoulos, K., Hashim, H., Kilonzo, M., Larcombe, J., Little, P., Murchie, P., Myint, P. K., N'Dow, J., Paterson, C., Powell, K., Scotland, G., Thiruchelvam, N., Norrie, J., Omar, M. I., MacLennan, S.
    BMJ Open, vol. 15, no. 4, e087206
    Contributions to Journals: Articles

View My Publications

Research

Research Overview

Clinical trials methodology

Clinical trial management

Research Areas

Applied Health Sciences

View Research Area

Current Research

VUE Trial: Vault or Uterine prolapse surgery evaluation: Two parallel randomised controlled trials of surgical options for upper compartment (vault or uterine) pelvic organ prolapse.

MASTER Trial: investigating the surgical treatment of male stress incontinence after prostate surgery.

ASICA: Achieving Self-Directed Integrated Cancer Aftercare (ASICA) in melanoma: A randomised patient-focused trial of delivering the ASICA intervention as a means to earlier detection of recurrent and second primary melanoma

CATHETER II Trial: evaluating the effect of weekly saline or acidic prophylactic catheter washout policies with standard care on catheter related complications.

Teaching

Teaching Responsibilities

I have supervised a number of BSc and MSc student research projects, including topics such as understanding patient's decision making to participate in clinical trials; rapid introduction of new cancer therapies; personalised cancer therapies; and investigation of the mode of action novel cancer therapeutics.

Publications

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  • Patient and health care professionals’ perception of weekly prophylactic catheter washout in adults living with long-term catheters: Qualitative Study of the CATHETER II Trial

    Tripathee, S., Abdel-Fattah, M., Johnson, D., Constable, L., Cotton, S., MacLennan, G., Norrie, J., Omar, M. I., MacLennan, S.
    The International Continence Society
    Contributions to Conferences: Posters

  • Male sling is as good as more complex surgery for incontinence after prostate surgery

    Saul, H., Deeney, B., Cassidy, S., Kwint, J., Constable, L., Abrams, P.
    BMJ (Clinical research ed.), vol. 381, pp. 1179
    Contributions to Journals: Articles

  • User Experiences of a Digital Intervention to Support Total-Skin-Self-Examination by Melanoma Survivors: Nested Qualitative Evaluation Embedded in a Randomized Controlled Trial

    Reilly, F., Wani, N., Hall, S., Morgan, H. M., Allan, J., Constable, L., Ntessalen, M., Murchie, P.
    JMIR Dermatology, vol. 6, e39544
    Contributions to Journals: Articles

  • Randomised controlled trial comparing the clinical and cost-effectiveness of various washout policies versus no washout policy in preventing catheter associated complications in adults living with long-term catheters: study protocol for the CATHETER II study

    Abdel-fattah, M., Johnson, D., Constable, L., Thomas, R., Cotton, S., Tripathee, S., Cooper, D., Boran, S., Dimitropoulos, K., Evans, S., Granitsiotis, P., Hashim, H., Kilonzo, M., Larcombe, J., Little, P., MacLennan, S., Murchie, P., Myint, P., N’Dow, J., Norrie, J., Omar, M. I., Paterson, C., Scotland, G., Thiruchelvam, N., MacLennan, G.
    Trials, vol. 23, no. 1, 630
    Contributions to Journals: Articles

  • The Achieving Self-directed Integrated Cancer Aftercare Intervention for Detection of Recurrent and Second Primary Melanoma in Survivors of Melanoma: Pilot Randomized Controlled Trial

    Murchie, P., Constable, L., Hall, S., Brant, W., Allan, J., Johnston, M., Masthoff, J., Lee, A., Treweek, S., Ayansina, D., Proby, C., Rahman, K., Walter, F., Burrows, N., Durrani, A., Maclennan, G.
    JMIR cancer, vol. 8, no. 3, e37539
    Contributions to Journals: Articles

  • Synthetic sling or artificial urinary sphincter for men with urodynamic stress incontinence after prostate surgery: the MASTER non-inferiority RCT

    Constable, L., Abrams, P., Cooper, D., Kilonzo, M., Cotterill, N., Harding, C. K., Drake, M. J., Pardoe, M. N., McDonald, A., Smith, R., Norrie, J., McCormack, K., Ramsay, C., Uren, A., Mundy, T., Glazener, C., MacLennan, G.
    Health Technology Assessment, vol. 26, no. 36, 184
    Contributions to Journals: Articles

  • Achieving Integrated Self-Directed Cancer Aftercare (ASICA) for melanoma: How a digital intervention to support total skin self-examination was used by people treated for cutaneous melanoma

    Reilly, F., Constable, L., Brant, W., Rahman, K., Durrani, A., Burrows, N., Proby, C., Allan, J., Johnston, M., Johnston, D., Walter, F., Murchie, P.
    BMC Cancer, vol. 21, 1217
    Contributions to Journals: Articles

  • Outcomes of a non-inferiority randomised controlled trial of surgery for men with urodynamic stress incontinence after prostate surgery (MASTER)

    Abrams, P., Constable, L., Cooper, D., MacLennan, G., Drake, M. J., Harding, C., Mundy, A., McCormack, K., McDonald, A., Norrie, J., Ramsay, C., Smith, R., Cotterill, N., Kilonzo, M., Glazener, C., MASTER trial team
    European Urology, vol. 79, no. 6, pp. 812-823
    Contributions to Journals: Articles

  • Providing trial results to participants in Phase III pragmatic effectiveness RCTs: a scoping review

    Bruhn, H., Cowan, E., Campbell, M., Constable, L., Cotton, S., Entwistle, V., Humphreys, R., Innes, K., Jayacodi, S., Jayacodi, S., Knapp, P., South, A., Gillies, K.
    Trials, vol. 22, 361
    Contributions to Journals: Articles

  • It is unprecedented: trial management during the COVID-19 pandemic and beyond

    Mitchell, E. J., Ahmed, K., Breeman, S., Cotton, S., Constable, L., Ferry, G., Goodman, K., Hickey, H., Meakin, G., Mironov, K., Quann, N., Wakefield, N., McDonald, A.
    Trials, vol. 21, pp. 784
    Contributions to Journals: Articles
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