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The Institute of Medical Sciences

Dr Felix Grassmann

Dr Felix Grassmann
Dr Felix Grassmann
Dr Felix Grassmann

Honorary Senior Lecturer

About
Email Address
felix.grassmann@abdn.ac.uk
Office Address
Institute of Medical Sciences
Foresterhill Campus
Ashgrove Road West
AB25 2ZD

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School/Department
School of Medicine, Medical Sciences and Nutrition
Personal Website

Biography

I received my PhD in the field of human genetics from the University of Regensburg, Germany. I spent several years as a postdoctoral researcher at the Karolinska Institute in Stockholm, Sweden and was appointed as Senior Lecturer of Bioinformatics and Biostatistics at the Institute of Medical Sciences. Currently, I am a Professor of Epidemiology and the Health and Medical University in Potsdam, Germany as well as a Honorary Senior Lecturer at the IMS in Aberdeen.

Prizes and Awards

2018               Leopoldina Postdoc Fellowship

2016               Travel Grant “RD Meeting Travel Grant” 2016 (Kyoto, Japan)

2016               Pro Retina “Makula-Forschungspreis” (Excellence in Visual Science Award)

2015               Distinguished PhD-Thesis Award (University of Regensburg)

2015              Travel Grant “ARVO Travel Grant“ 2015 (Denver, Colorado, USA)

2012             ProRetina Travel Award (RD Meeting 2012)

2009             Alumni Award University of Regensburg

2009             ProRetina Poster Award

Research

Research Overview

The main focus of my research is to understand the inherited and acquired genetics in complex diseases. To this end, I am working with public datasets as well as consortia to generate the largest datasets for each disease of interest. I am particularly interested in diseases with a significant individual and societal burden in aging populations such as age-related macular degeneration, breast cancer and cardiometabolic diseases. My group uses the full spectrum of high-throughput omics tools available to understand the underlying biology behind those diseases with the potential to uncover novel ways to treat of prevent them.

Research Areas

Biomedical Sciences

Supervising
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Applied Health Sciences

Supervising
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Research Specialisms

  • Bioinformatics
  • Biomedical Sciences
  • Epidemiology
  • Human Genetics
  • Statistics

Our research specialisms are based on the Higher Education Classification of Subjects (HECoS) which is HESA open data, published under the Creative Commons Attribution 4.0 International licence.

Publications

Page 4 of 6 Results 31 to 40 of 60

  • Pleiotropic effects of risk factors in age-related macular degeneration and seemingly unrelated complex diseases

    Kiel, C., Weber, B. H., Grassmann, F.
    Retinal Degenerative Diseases. Ash, J. D., Anderson, R. E., LaVail, M. M., Rickman, C. B., Hollyfield, J. G. (eds.). Springer New York LLC, pp. 247-255, 9 pages
    Chapters in Books, Reports and Conference Proceedings: Chapters

  • A mega-analysis of expression quantitative trait loci (eQTL) provides insight into the regulatory architecture of gene expression variation in liver

    Strunz, T., Grassmann, F., Gayán, J., Nahkuri, S., Souza-Costa, D., Maugeais, C., Fauser, S., Nogoceke, E., Weber, B. H.
    Scientific Reports, vol. 8, 5865
    Contributions to Journals: Articles

  • A Deep Learning Algorithm for Prediction of Age-Related Eye Disease Study Severity Scale for Age-Related Macular Degeneration from Color Fundus Photography

    Grassmann, F., Mengelkamp, J., Brandl, C., Harsch, S., Zimmermann, M. E., Linkohr, B., Peters, A., Heid, I. M., Palm, C., Weber, B. H.
    Ophthalmology, vol. 125, no. 9, pp. 1410-1420
    Contributions to Journals: Articles

  • Investigating the modulation of genetic effects on late AMD by age and sex: Lessons learned and two additional loci

    Winkler, T. W., Brandl, C., Grassmann, F., Gorski, M., Stark, K., Loss, J., Weber, B. H., Heid, I. M., International Age-related Macular Degeneration Genomics Consortium (IAMDGC)
    PloS ONE, vol. 13, no. 3, e0194321
    Contributions to Journals: Articles

  • Genetic pleiotropy between age-related macular degeneration and 16 complex diseases and traits

    Grassmann, F., Kiel, C., Zimmermann, M. E., Gorski, M., Grassmann, V., Stark, K., Heid, I. M., Weber, B. H., Fritsche, L. G., Igl, W., Bailey, J. N., Sengupta, S., Bragg-Gresham, J. L., Burdon, K. P., Hebbring, S. J., Wen, C., Kim, I. K., Cho, D., Zack, D., Souied, E., Scholl, H. P., Bala, E., Lee, K. E., Hunter, D. J., Sardell, R. J., Mitchell, P., Merriam, J. E., Cipriani, V., Hoffman, J. D., Schick, T., Lechanteur, Y. T., Guymer, R. H., Johnson, M. P., Jiang, Y., Stanton, C. M., Buitendijk, G. H., Zhan, X., Kwong, A. M., Boleda, A., Brooks, M., Gieser, L., Ratnapriya, R., Branham, K. E., Foerster, J. R., Heckenlively, J. R., Othman, M. I., Vote, B. J., Liang, H. H., Souzeau, E., McAllister, I. L., International AMD Genomics Consortium (IAMDGC)
    Genome Medicine, vol. 9, 29
    Contributions to Journals: Articles

  • Recombinant Haplotypes Narrow the ARMS2/HTRA1 Association Signal for Age-Related Macular Degeneration

    Grassmann, F., Heid, I. M., Weber, B. H., Fritsche, L. G., Igl, W., Bailey, J. N., Sengupta, S., Bragg-Gresham, J. L., Burdon, K. P., Hebbring, S. J., Wen, C., Gorski, M., Kim, I. K., Cho, D., Zack, D., Souied, E., Scholl, H. P., Bala, E., Lee, K. E., Hunter, D. J., Sardell, R. J., Mitchell, P., Merriam, J. E., Cipriani, V., Hoffman, J. D., Schick, T., Lechanteur, Y. T., Guymer, R. H., Johnson, M. P., Jiang, Y., Stanton, C. M., Buitendijk, G. H., Zhan, X., Kwong, A. M., Boleda, A., Brooks, M., Gieser, L., Ratnapriya, R., Branham, K. E., Foerster, J. R., Heckenlively, J. R., Othman, M. I., Vote, B. J., Liang, H. H., Souzeau, E., McAllister, I. L., Isaacs, T., Hall, J., Lake, S., International AMD Genomics Consortium (IAMDGC)
    Genetics, vol. 205, no. 2, pp. 919-924
    Contributions to Journals: Articles

  • Age-related macular degeneration associated polymorphism rs10490924 in ARMS2 results in deficiency of a complement activator

    Micklisch, S., Lin, Y., Jacob, S., Karlstetter, M., Dannhausen, K., Dasari, P., von der Heide, M., Dahse, H. M., Schmölz, L., Grassmann, F., Alene, M., Fauser, S., Neumann, H., Lorkowski, S., Pauly, D., Weber, B. H., Joussen, A. M., Langmann, T., Zipfel, P. F., Skerka, C.
    Journal of Neuroinflammation, vol. 14, 4
    Contributions to Journals: Articles

  • Mutation spectrum of the ABCA4 gene in 335 stargardt disease patients from a multicenter German cohort—impact of selected deep intronic variants and common SNPs

    Schulz, H. L., Grassmann, F., Kellner, U., Spital, G., Rüther, K., Jägle, H., Hufendiek, K., Rating, P., Huchzermeyer, C., Baier, M. J., Weber, B. H., Stöhr, H.
    Investigative Ophthalmology and Visual Science, vol. 58, no. 1, pp. 394-403
    Contributions to Journals: Articles

  • An Eye on Age-Related Macular Degeneration: The Role of MicroRNAs in Disease Pathology

    Berber, P., Grassmann, F., Kiel, C., Weber, B. H.
    Molecular Diagnosis and Therapy, vol. 21, no. 1, pp. 31-43
    Contributions to Journals: Review articles

  • Genetische Risiken und Therapieentwicklung bei Netzhautdegenerationen

    Grassmann, F., Weber, B.
    Medizinische Genetik, vol. 29, no. 2, pp. 195-201
    Contributions to Journals: Review articles
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