Honorary Senior Lecturer
- About
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- Email Address
- felix.grassmann@abdn.ac.uk
- Office Address
- School/Department
- School of Medicine, Medical Sciences and Nutrition
Biography
I received my PhD in the field of human genetics from the University of Regensburg, Germany. I spent several years as a postdoctoral researcher at the Karolinska Institute in Stockholm, Sweden and was appointed as Senior Lecturer of Bioinformatics and Biostatistics at the Institute of Medical Sciences. Currently, I am a Professor of Epidemiology and the Health and Medical University in Potsdam, Germany as well as a Honorary Senior Lecturer at the IMS in Aberdeen.
Prizes and Awards
2018 Leopoldina Postdoc Fellowship
2016 Travel Grant “RD Meeting Travel Grant” 2016 (Kyoto, Japan)
2016 Pro Retina “Makula-Forschungspreis” (Excellence in Visual Science Award)
2015 Distinguished PhD-Thesis Award (University of Regensburg)
2015 Travel Grant “ARVO Travel Grant“ 2015 (Denver, Colorado, USA)
2012 ProRetina Travel Award (RD Meeting 2012)
2009 Alumni Award University of Regensburg
2009 ProRetina Poster Award
- Research
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Research Overview
The main focus of my research is to understand the inherited and acquired genetics in complex diseases. To this end, I am working with public datasets as well as consortia to generate the largest datasets for each disease of interest. I am particularly interested in diseases with a significant individual and societal burden in aging populations such as age-related macular degeneration, breast cancer and cardiometabolic diseases. My group uses the full spectrum of high-throughput omics tools available to understand the underlying biology behind those diseases with the potential to uncover novel ways to treat of prevent them.
Research Areas
Research Specialisms
- Bioinformatics
- Biomedical Sciences
- Epidemiology
- Human Genetics
- Statistics
Our research specialisms are based on the Higher Education Classification of Subjects (HECoS) which is HESA open data, published under the Creative Commons Attribution 4.0 International licence.
- Publications
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Association between breast cancer risk and disease aggressiveness: Characterizing underlying gene expression patterns
International Journal of Cancer, vol. 148, no. 4, pp. 884-894Contributions to Journals: ArticlesPleiotropic Locus 15q24.1 Reveals a Gender-Specific Association with Neovascular but Not Atrophic Age-Related Macular Degeneration (AMD)
Cells, vol. 9, no. 10, 2257Contributions to Journals: Articles- [ONLINE] DOI: https://doi.org/10.3390/cells9102257
- [OPEN ACCESS] http://aura.abdn.ac.uk/bitstream/2164/15353/1/Kiel_PlleiotropicLens_VOR.pdf
- [ONLINE] View publication in Scopus
The association of single nucleotide polymorphisms (SNPs) with breast density and breast cancer survival: the Malmö Diet and Cancer Study
Acta radiologica (Stockholm, Sweden : 1987), vol. 61, no. 10, pp. 1326-1334Contributions to Journals: ArticlesA mega-analysis of expression quantitative trait loci in retinal tissue
PLoS Genetics, vol. 16, no. 9, pp. e1008934Contributions to Journals: Articles- [ONLINE] DOI: https://doi.org/10.1371/journal.pgen.1008934
- [ONLINE] View publication in Scopus
Genome-wide association meta-analysis for early age-related macular degeneration highlights novel loci and insights for advanced disease
BMC Medical Genomics, vol. 13, 120Contributions to Journals: ArticlesA Circulating MicroRNA Profile in a Laser-Induced Mouse Model of Choroidal Neovascularization
International Journal of Molecular Sciences, vol. 21, no. 8, 2689Contributions to Journals: ArticlesInsights into the loss of the Y chromosome with age in control individuals and in patients with age-related macular degeneration using genotyping microarray data
Human Genetics, vol. 139, pp. 401-407Contributions to Journals: Articles- [ONLINE] DOI: https://doi.org/10.1007/s00439-019-02029-1
- [ONLINE] View publication in Scopus
CYP2D6 Genotype Predicts Tamoxifen Discontinuation and Prognosis in Patients With Breast Cancer
Journal of Clinical Oncology, vol. 38, no. 6, pp. 548-557Contributions to Journals: Articles- [ONLINE] DOI: https://doi.org/10.1200/JCO.19.01535
- [ONLINE] View publication in Scopus
Complement C3 Inhibitor Pegcetacoplan for Geographic Atrophy Secondary to Age-Related Macular Degeneration: A Randomized Phase 2 Trial
Ophthalmology, vol. 127, no. 2, pp. 186-195Contributions to Journals: Articles- [ONLINE] DOI: https://doi.org/10.1016/j.ophtha.2019.07.011
- [OPEN ACCESS] http://aura.abdn.ac.uk/bitstream/2164/14537/1/Liao_AAO_Complement_VOR.pdf
- [ONLINE] View publication in Scopus
A transcriptome-wide association study based on 27 tissues identifies 106 genes potentially relevant for disease pathology in age-related macular degeneration
Scientific Reports, vol. 10, 1584Contributions to Journals: Articles