Dr Felix Grassmann

Dr Felix Grassmann
Dr Felix Grassmann
Dr Felix Grassmann

Honorary Senior Lecturer

About
Email Address
felix.grassmann@abdn.ac.uk
Office Address
Institute of Medical Sciences
Foresterhill Campus
Ashgrove Road West
AB25 2ZD

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School/Department
School of Medicine, Medical Sciences and Nutrition

Biography

I received my PhD in the field of human genetics from the University of Regensburg, Germany. I spent several years as a postdoctoral researcher at the Karolinska Institute in Stockholm, Sweden and was appointed as Senior Lecturer of Bioinformatics and Biostatistics at the Institute of Medical Sciences. Currently, I am a Professor of Epidemiology and the Health and Medical University in Potsdam, Germany as well as a Honorary Senior Lecturer at the IMS in Aberdeen.

Prizes and Awards

2018               Leopoldina Postdoc Fellowship

2016               Travel Grant “RD Meeting Travel Grant” 2016 (Kyoto, Japan)

2016               Pro Retina “Makula-Forschungspreis” (Excellence in Visual Science Award)

2015               Distinguished PhD-Thesis Award (University of Regensburg)

2015              Travel Grant “ARVO Travel Grant“ 2015 (Denver, Colorado, USA)

2012             ProRetina Travel Award (RD Meeting 2012)

2009             Alumni Award University of Regensburg

2009             ProRetina Poster Award

Research

Research Overview

The main focus of my research is to understand the inherited and acquired genetics in complex diseases. To this end, I am working with public datasets as well as consortia to generate the largest datasets for each disease of interest. I am particularly interested in diseases with a significant individual and societal burden in aging populations such as age-related macular degeneration, breast cancer and cardiometabolic diseases. My group uses the full spectrum of high-throughput omics tools available to understand the underlying biology behind those diseases with the potential to uncover novel ways to treat of prevent them.

Research Areas

Biomedical Sciences

Supervising

Applied Health Sciences

Supervising

Research Specialisms

  • Bioinformatics
  • Biomedical Sciences
  • Epidemiology
  • Human Genetics
  • Statistics

Our research specialisms are based on the Higher Education Classification of Subjects (HECoS) which is HESA open data, published under the Creative Commons Attribution 4.0 International licence.

Publications

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  • Common synonymous variants in ABCA4 are protective for chloroquine induced maculopathy (toxic maculopathy) Neuro-ophthalmology

    Grassmann, F., Bergholz, R., Mändl, J., Jägle, H., Ruether, K., Weber, B. H.
    BMC Ophthalmology, vol. 15, 18
    Contributions to Journals: Articles
  • Rare and common variants in extracellular matrix gene Fibrillin 2 (FBN2) are associated with macular degeneration

    Ratnapriya, R., Zhan, X., Fariss, R. N., Branham, K. E., Zipprer, D., Chakarova, C. F., Sergeev, Y. V., Campos, M. M., Othman, M., Friedman, J. S., Maminishkis, A., Waseem, N. H., Brooks, M., Rajasimha, H. K., Edwards, A. O., Lotery, A., Klein, B. E., Truitt, B. J., Li, B., Schaumberg, D. A., Morgan, D. J., Morrison, M. A., Souied, E., Tsironi, E. E., Grassmann, F., Fishman, G. A., Silvestri, G., Scholl, H. P., Kim, I. K., Ramke, J., Tuo, J., Merriam, J. E., Merriam, J. C., Park, K. H., Olson, L. M., Farrer, L. A., Johnson, M. P., Peachey, N. S., Lathrop, M., Baron, R. V., Igo, R. P., Klein, R., Hagstrom, S. A., Kamatani, Y., Martin, T. M., Jiang, Y., Conley, Y., Sahel, J. A., Zack, D. J., Chan, C. C., Pericak-Vance, M. A., Jacobson, S. G., Gorin, M. B., Klein, M. L., Allikmets, R., Iyengar, S. K., Weber, B. H., Haines, J. L., Léveillard, T., Deangelis, M. M., Stambolian, D., Weeks, D. E., Bhattacharya, S. S., Chew, E. Y., Heckenlively, J. R., Abecasis, G. R., Swaroop, A.
    Human Molecular Genetics, vol. 23, no. 21, pp. 5827-5837
    Contributions to Journals: Articles
  • A circulating MicroRNA profile is associated with late- stage neovascular age-related macular degeneration

    Grassmann, F., Schoenberger, P. G., Brandl, C., Schick, T., Hasler, D., Meister, G., Fleckenstein, M., Lindner, M., Helbig, H., Fauser, S., Weber, B. H.
    PloS ONE, vol. 9, no. 9, e0107461
    Contributions to Journals: Articles
  • In-depth characterisation of retinal pigment epithelium (RPE) cells derived from human induced pluripotent stem cells (hiPSC)

    Brandl, C., Zimmermann, S. J., Milenkovic, V. M., Rosendahl, S. M., Grassmann, F., Milenkovic, A., Hehr, U., Federlin, M., Wetzel, C. H., Helbig, H., Weber, B. H.
    NeuroMolecular Medicine, vol. 16, no. 3, pp. 551-564
    Contributions to Journals: Articles
  • Bedeutung des komplementsystems für die altersabhängige makuladegeneration

    Weber, B. H., Charbel Issa, P., Pauly, D., Herrmann, P., Grassmann, F., Holz, F. G.
    Deutsches Arzteblatt International, vol. 111, no. 8, pp. 133-138
    Contributions to Journals: Articles
  • Genetic risk models in age-related macular degeneration

    Grassmann, F., Heid, I. M., Weber, B. H.
    Advances in Experimental Medicine and Biology, vol. 801, pp. 291-300
    Contributions to Journals: Articles
  • Identification of a rare coding variant in complement 3 associated with age-related macular degeneration

    Zhan, X., Larson, D. E., Wang, C., Koboldt, D. C., Sergeev, Y. V., Fulton, R. S., Fulton, L. L., Fronick, C. C., Branham, K. E., Bragg-Gresham, J., Jun, G., Hu, Y., Kang, H. M., Liu, D., Othman, M., Brooks, M., Ratnapriya, R., Boleda, A., Grassmann, F., Von Strachwitz, C., Olson, L. M., Buitendijk, G. H., Hofman, A., Van Duijn, C. M., Cipriani, V., Moore, A. T., Shahid, H., Jiang, Y., Conley, Y. P., Morgan, D. J., Kim, I. K., Johnson, M. P., Cantsilieris, S., Richardson, A. J., Guymer, R. H., Luo, H., Ouyang, H., Licht, C., Pluthero, F. G., Zhang, M. M., Zhang, K., Baird, P. N., Blangero, J., Klein, M. L., Farrer, L. A., DeAngelis, M. M., Weeks, D. E., Gorin, M. B., Yates, J. R., Klaver, C. C., Pericak-Vance, M. A., Haines, J. L., Weber, B. H., Wilson, R. K., Heckenlively, J. R., Chew, E. Y., Stambolian, D., Mardis, E. R., Swaroop, A., Abecasis, G. R.
    Nature Genetics, vol. 45, no. 11, pp. 1375-1379
    Contributions to Journals: Letters
  • The retinitis pigmentosa 28 protein FAM161A is a novel ciliary protein involved in intermolecular protein interaction and microtubule association

    Zach, F., Grassmann, F., Langmann, T., Sorusch, N., Wolfrum, U., Stöhr, H.
    Human Molecular Genetics, vol. 21, no. 21, pp. 4573-4586
    Contributions to Journals: Articles
  • Modelling the genetic risk in age-related macular degeneration

    Grassmann, F., Fritsche, L. G., Keilhauer, C. N., Heid, I. M., Weber, B. H.
    PloS ONE, vol. 7, no. 5, e37979
    Contributions to Journals: Articles
  • Wie groß sind die kleinen genetischen Risiken?

    Heid, I. M., Winkler, T. W., Grassmann, F., Weber, B. H.
    Medizinische Genetik, vol. 23, no. 3, pp. 377-384
    Contributions to Journals: Articles
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