Honorary Senior Lecturer
- About
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- Email Address
- felix.grassmann@abdn.ac.uk
- Office Address
- School/Department
- School of Medicine, Medical Sciences and Nutrition
Biography
I received my PhD in the field of human genetics from the University of Regensburg, Germany. I spent several years as a postdoctoral researcher at the Karolinska Institute in Stockholm, Sweden and was appointed as Senior Lecturer of Bioinformatics and Biostatistics at the Institute of Medical Sciences. Currently, I am a Professor of Epidemiology and the Health and Medical University in Potsdam, Germany as well as a Honorary Senior Lecturer at the IMS in Aberdeen.
Prizes and Awards
2018 Leopoldina Postdoc Fellowship
2016 Travel Grant “RD Meeting Travel Grant” 2016 (Kyoto, Japan)
2016 Pro Retina “Makula-Forschungspreis” (Excellence in Visual Science Award)
2015 Distinguished PhD-Thesis Award (University of Regensburg)
2015 Travel Grant “ARVO Travel Grant“ 2015 (Denver, Colorado, USA)
2012 ProRetina Travel Award (RD Meeting 2012)
2009 Alumni Award University of Regensburg
2009 ProRetina Poster Award
- Research
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Research Overview
The main focus of my research is to understand the inherited and acquired genetics in complex diseases. To this end, I am working with public datasets as well as consortia to generate the largest datasets for each disease of interest. I am particularly interested in diseases with a significant individual and societal burden in aging populations such as age-related macular degeneration, breast cancer and cardiometabolic diseases. My group uses the full spectrum of high-throughput omics tools available to understand the underlying biology behind those diseases with the potential to uncover novel ways to treat of prevent them.
Research Areas
Research Specialisms
- Bioinformatics
- Biomedical Sciences
- Epidemiology
- Human Genetics
- Statistics
Our research specialisms are based on the Higher Education Classification of Subjects (HECoS) which is HESA open data, published under the Creative Commons Attribution 4.0 International licence.
- Publications
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Loss of GPR75 protects against non-alcoholic fatty liver disease and body fat accumulation
Cell MetabolismContributions to Journals: ArticlesAn ancient polymorphic regulatory region within the BDNF gene associated with obesity modulates anxiety-like behaviour in mice and humans
Molecular PsychiatryContributions to Journals: Articles- [ONLINE] DOI: https://doi.org/10.1038/s41380-023-02359-7
A genome-wide gene-environment interaction study of breast cancer risk for women of European ancestry
Breast Cancer Research, vol. 25, no. 1, pp. 93Contributions to Journals: ArticlesLow leukocyte mitochondrial DNA abundance drives atherosclerotic cardiovascular diseases: a cohort and Mendelian randomization study
Cardiovascular Research, vol. 119, no. 4, pp. 998-1007Contributions to Journals: Articles- [ONLINE] DOI: https://doi.org/10.1093/cvr/cvac182
The association between mitochondrial DNA abundance and stroke: A combination of multivariable-adjusted survival and Mendelian randomization analyses
Atherosclerosis, vol. 354, pp. 1-7Contributions to Journals: ArticlesSeed sequence polymorphism rs2168518 and allele-specific target gene regulation of hsa-miR-4513
Human Molecular Genetics, vol. 31, no. 6, pp. 875-887Contributions to Journals: ArticlesCYP2D6 genotype predicts tamoxifen discontinuation and drug response: a secondary analysis of the KARISMA trial
Annals of Oncology, vol. 32, no. 10, pp. 1286-1293Contributions to Journals: ArticlesLymph node metastases in breast cancer: investigating associations with tumor characteristics, molecular subtypes, and polygenic risk score using a continuous growth model
International Journal of Cancer, vol. 149, no. 6, pp. 1348-1357Contributions to Journals: ArticlesMammographic features are associated with cardiometabolic disease risk and mortality
European Heart Journal, vol. 42, no. 34, pp. 3361–3370Contributions to Journals: ArticlesDeciphering the genetic and epidemiological landscape of mitochondrial DNA abundance
Human Genetics, vol. 140, pp. 849-861Contributions to Journals: Articles
