Honorary Senior Lecturer
- About
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- Email Address
- felix.grassmann@abdn.ac.uk
- Office Address
- School/Department
- School of Medicine, Medical Sciences and Nutrition
Biography
I received my PhD in the field of human genetics from the University of Regensburg, Germany. I spent several years as a postdoctoral researcher at the Karolinska Institute in Stockholm, Sweden and was appointed as Senior Lecturer of Bioinformatics and Biostatistics at the Institute of Medical Sciences. Currently, I am a Professor of Epidemiology and the Health and Medical University in Potsdam, Germany as well as a Honorary Senior Lecturer at the IMS in Aberdeen.
Prizes and Awards
2018 Leopoldina Postdoc Fellowship
2016 Travel Grant “RD Meeting Travel Grant” 2016 (Kyoto, Japan)
2016 Pro Retina “Makula-Forschungspreis” (Excellence in Visual Science Award)
2015 Distinguished PhD-Thesis Award (University of Regensburg)
2015 Travel Grant “ARVO Travel Grant“ 2015 (Denver, Colorado, USA)
2012 ProRetina Travel Award (RD Meeting 2012)
2009 Alumni Award University of Regensburg
2009 ProRetina Poster Award
- Research
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Research Overview
The main focus of my research is to understand the inherited and acquired genetics in complex diseases. To this end, I am working with public datasets as well as consortia to generate the largest datasets for each disease of interest. I am particularly interested in diseases with a significant individual and societal burden in aging populations such as age-related macular degeneration, breast cancer and cardiometabolic diseases. My group uses the full spectrum of high-throughput omics tools available to understand the underlying biology behind those diseases with the potential to uncover novel ways to treat of prevent them.
Research Areas
Research Specialisms
- Bioinformatics
- Biomedical Sciences
- Epidemiology
- Human Genetics
- Statistics
Our research specialisms are based on the Higher Education Classification of Subjects (HECoS) which is HESA open data, published under the Creative Commons Attribution 4.0 International licence.
- Publications
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Interval breast cancer is associated with other types of tumors
Nature Communications, vol. 10, 4648Contributions to Journals: ArticlesCost-effective molecular inversion probe-based ABCA4 sequencing reveals deep-intronic variants in Stargardt disease
Human Mutation, vol. 40, no. 10, pp. 1749-1759Contributions to Journals: Articles- [ONLINE] DOI: https://doi.org/10.1002/humu.23787
- [ONLINE] View publication in Scopus
Deep-intronic ABCA4 variants explain missing heritability in Stargardt disease and allow correction of splice defects by antisense oligonucleotides
Genetics in Medicine, vol. 21, no. 8, pp. 1751-1760Contributions to Journals: ArticlesThe agonistic TSPO ligand XBD173 attenuates the glial response thereby protecting inner retinal neurons in a murine model of retinal ischemia
Journal of Neuroinflammation, vol. 16, 43Contributions to Journals: Articles- [ONLINE] DOI: https://doi.org/10.1186/s12974-019-1424-5
- [OPEN ACCESS] http://aura.abdn.ac.uk/bitstream/2164/14979/1/Mages_etal_JN_Agonistic_VOR.pdf
- [ONLINE] View publication in Scopus
Conduct and Quality Control of Differential Gene Expression Analysis Using High-Throughput Transcriptome Sequencing (RNASeq)
Methods in Molecular Biology. HUMANA PRESS INC, pp. 29-43, 15 pagesChapters in Books, Reports and Conference Proceedings: Chapters- [ONLINE] DOI: https://doi.org/10.1007/978-1-4939-8669-9_2
- [ONLINE] View publication in Scopus
Y chromosome mosaicism is associated with age-related macular degeneration
European Journal of Human Genetics, vol. 27, pp. 36-41Contributions to Journals: ArticlesAssessment of Novel Genome-Wide Significant Gene Loci and Lesion Growth in Geographic Atrophy Secondary to Age-Related Macular Degeneration
JAMA Ophthalmology, vol. 137, no. 8, pp. 867-876Contributions to Journals: Articles- [ONLINE] DOI: https://doi.org/10.1001/jamaophthalmol.2019.1318
- [ONLINE] View publication in Scopus
Spectral domain optical coherence tomography allows the unification of clinical decision making for the evaluation of choroidal neovascularization activity
Ophthalmologica, vol. 241, no. 1, pp. 32-37Contributions to Journals: Articles- [ONLINE] DOI: https://doi.org/10.1159/000489344
- [ONLINE] View publication in Scopus
Evaluation of serum sphingolipids and the influence of genetic risk factors in age-related macular degeneration
PloS ONE, vol. 13, no. 8, e0200739Contributions to Journals: ArticlesRecurrent structural variation, clustered sites of selection, and disease risk for the complement factor H (CFH) gene family
Proceedings of the National Academy of Sciences of the United States of America, vol. 115, no. 19, pp. E4433-E4442Contributions to Journals: Articles