Honorary Senior Lecturer
- About
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- Email Address
- felix.grassmann@abdn.ac.uk
- Office Address
- School/Department
- School of Medicine, Medical Sciences and Nutrition
Biography
I received my PhD in the field of human genetics from the University of Regensburg, Germany. I spent several years as a postdoctoral researcher at the Karolinska Institute in Stockholm, Sweden and was appointed as Senior Lecturer of Bioinformatics and Biostatistics at the Institute of Medical Sciences. Currently, I am a Professor of Epidemiology and the Health and Medical University in Potsdam, Germany as well as a Honorary Senior Lecturer at the IMS in Aberdeen.
Prizes and Awards
2018 Leopoldina Postdoc Fellowship
2016 Travel Grant “RD Meeting Travel Grant” 2016 (Kyoto, Japan)
2016 Pro Retina “Makula-Forschungspreis” (Excellence in Visual Science Award)
2015 Distinguished PhD-Thesis Award (University of Regensburg)
2015 Travel Grant “ARVO Travel Grant“ 2015 (Denver, Colorado, USA)
2012 ProRetina Travel Award (RD Meeting 2012)
2009 Alumni Award University of Regensburg
2009 ProRetina Poster Award
- Research
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Research Overview
The main focus of my research is to understand the inherited and acquired genetics in complex diseases. To this end, I am working with public datasets as well as consortia to generate the largest datasets for each disease of interest. I am particularly interested in diseases with a significant individual and societal burden in aging populations such as age-related macular degeneration, breast cancer and cardiometabolic diseases. My group uses the full spectrum of high-throughput omics tools available to understand the underlying biology behind those diseases with the potential to uncover novel ways to treat of prevent them.
Research Areas
Research Specialisms
- Bioinformatics
- Biomedical Sciences
- Epidemiology
- Human Genetics
- Statistics
Our research specialisms are based on the Higher Education Classification of Subjects (HECoS) which is HESA open data, published under the Creative Commons Attribution 4.0 International licence.
- Publications
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Pleiotropic effects of risk factors in age-related macular degeneration and seemingly unrelated complex diseases
Retinal Degenerative Diseases. Ash, J. D., Anderson, R. E., LaVail, M. M., Rickman, C. B., Hollyfield, J. G. (eds.). Springer New York LLC, pp. 247-255, 9 pagesChapters in Books, Reports and Conference Proceedings: Chapters- [ONLINE] DOI: https://doi.org/10.1007/978-3-319-75402-4_30
- [ONLINE] View publication in Scopus
A mega-analysis of expression quantitative trait loci (eQTL) provides insight into the regulatory architecture of gene expression variation in liver
Scientific Reports, vol. 8, 5865Contributions to Journals: ArticlesA Deep Learning Algorithm for Prediction of Age-Related Eye Disease Study Severity Scale for Age-Related Macular Degeneration from Color Fundus Photography
Ophthalmology, vol. 125, no. 9, pp. 1410-1420Contributions to Journals: ArticlesInvestigating the modulation of genetic effects on late AMD by age and sex: Lessons learned and two additional loci
PloS ONE, vol. 13, no. 3, e0194321Contributions to Journals: ArticlesGenetic pleiotropy between age-related macular degeneration and 16 complex diseases and traits
Genome Medicine, vol. 9, 29Contributions to Journals: ArticlesRecombinant Haplotypes Narrow the ARMS2/HTRA1 Association Signal for Age-Related Macular Degeneration
Genetics, vol. 205, no. 2, pp. 919-924Contributions to Journals: ArticlesAge-related macular degeneration associated polymorphism rs10490924 in ARMS2 results in deficiency of a complement activator
Journal of Neuroinflammation, vol. 14, 4Contributions to Journals: ArticlesMutation spectrum of the ABCA4 gene in 335 stargardt disease patients from a multicenter German cohort—impact of selected deep intronic variants and common SNPs
Investigative Ophthalmology and Visual Science, vol. 58, no. 1, pp. 394-403Contributions to Journals: Articles- [ONLINE] DOI: https://doi.org/10.1167/iovs.16-19936
- [ONLINE] View publication in Scopus
An Eye on Age-Related Macular Degeneration: The Role of MicroRNAs in Disease Pathology
Molecular Diagnosis and Therapy, vol. 21, no. 1, pp. 31-43Contributions to Journals: Review articles- [ONLINE] DOI: https://doi.org/10.1007/s40291-016-0234-z
- [ONLINE] View publication in Scopus
Genetische Risiken und Therapieentwicklung bei Netzhautdegenerationen
Medizinische Genetik, vol. 29, no. 2, pp. 195-201Contributions to Journals: Review articles- [ONLINE] DOI: https://doi.org/10.1007/s11825-017-0134-6
- [ONLINE] View publication in Scopus