Duration: 01 November 2021 - 30 November 2026
Funder: British Society for Antimicrobial Chemotherapy
Chief investigators: Professor Gary Macfarlane, Professor Gareth Jones
Other co-investigators: Professor Patrice Forget, Dr Callum Kaye (NHS Grampian), Dr Noha El Sakka (NHS Grampian)
Study coordinators: Laura Moir, Rebecca Parr
Project assistant: Jay Woods
Effective antimicrobial agents are a crucial component of modern medicine allowing the elimination or inhibition of growth of all microorganisms. However, their effectiveness is threatened by evolutionary development of certain microbes. According to the WHO, antimicrobial resistance is increasing world-wide, and compromising our ability to treat infectious diseases and undermining many other advances in health and medicine. The purpose of the UKAR is to answer a broad set of research questions around novel anti-microbial agents. It will allow us to describe the use of such novel agents throughout the UK and to quantify the clinical outcomes and safety profile associated with their use in a real world setting.
Enquiries about the study can be emailed to ukar@abdn.ac.uk.
You can find out more about the registry, including the latest study news, at the BSAC study webpages.
If you are a clinician who is interested in antimicrobial resistance, please follow the link or QR code below to the UKAR Study Expression of Interest form:
https://forms.office.com/UKAR-EOI
Participating hospital sites
- News
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Articles
29-May-2024: There’s still time to get involved in this important AMR research
01-Feb-2024: UKAR: The secrets of successful study site
01-Jan-2024: P15 UK Antimicrobial Registry Study: progress to date
28-Apr-2023: University of Aberdeen scientists fight back against global public health emergency
18-Apr-2023: Aberdeen University researchers are collaborating with BSAC to create the first UK Antimicrobial Registry (UKAR)
Tweets
The #UKARStudy team is delighted to welcome @DennisJisha as Assistant Study Coordinator. To #getinvolvedinresearch and learn more about being a recruiting centre for the @BSACandJAC collaboration, please get in touch with the team; ukar@abdn.ac.uk #antimicrobialresistance #AMR pic.twitter.com/3BMc7ztwE3
— UoAEpidemiology (@UoAEpi) August 28, 2024The #UKARStudy team bid a very fond farewell today to Study Coordinator @lauramoir66 who has been a dedicated member of the Epidemiology group for the past 6 years. We all wish Laura well as she embarks on her next role with @hsru_aberdeen #getinvolvedinresearch #clinicalresearch pic.twitter.com/VFPkz6hGfx
— UoAEpidemiology (@UoAEpi) August 23, 2024TERRIFIC THURSDAY: The #UKARStudy team are delighted to open another site for #participant recruitment to the @BSACandJAC UK Antimicrobial Registry. Today we say croeso & diolch to colleagues @CwmTafMorgannwg. We’re looking forward to working with you #AMR #getinvolvedinresearch pic.twitter.com/H28rLg3Y3r
— UoAEpidemiology (@UoAEpi) August 22, 2024THANKFUL THURSDAY: The #UKARStudy team are delighted to open another site for #participant recruitment to the @BSACandJAC UK Antimicrobial Registry. Today we welcome colleagues from @StGeorgesTrust. We’re really looking forward to working with you #AMR #getinvolvedinresearch pic.twitter.com/a5S0jhcbQU
— UoAEpidemiology (@UoAEpi) August 8, 2024The #UKARStudy team are delighted to announce that an introduction to the @BSACandJAC collaboration has been published in JAC-Antimicrobial Resistance | Oxford Academic (https://t.co/bSYLKJiCir) https://t.co/YrtmDK4wo0
— UoAEpidemiology (@UoAEpi) August 6, 2024WONDERFUL WEDNESDAY: The #UKARStudy team are delighted to open another site for #participant recruitment to the @BSACandJAC UK Antimicrobial Registry. Today we welcome colleagues from Plymouth @UHP_NHS @RDInUHP We’re looking forward to working with you #AMR #getinvolvedinresearch pic.twitter.com/2xs3AIznS1
— UoAEpidemiology (@UoAEpi) July 3, 2024The #UKARStudy are looking for a dynamic, dedicated, motivated team player with an interest in #antimicrobialresistance to come and work with us on the @BSACandJAC UK Antimicrobial Registry. Closing date 01-July-2024; https://t.co/a6LYNwTOMK
— UoAEpidemiology (@UoAEpi) June 25, 2024TERRIFIC TUESDAY: The #UKARStudy team are delighted to welcome Barnsley Hospital NHS Foundation Trust as a #participant recruiting centre in the @BSACandJAC UK Antimicrobial Registry. We look forward to working with you #antimicrobialresistance #AMR #getinvolvedinresearch pic.twitter.com/uNtH6G2PuH
— UoAEpidemiology (@UoAEpi) June 25, 2024NEW STUDY SITE: The #UKARStudy team are delighted to welcome @BucksHealthcare as a #participant recruiting centre in the @BSACandJAC UK Antimicrobial Registry. We look forward to working with you on this #antimicrobialresistance study. #AMR #getinvolvedinresearch pic.twitter.com/edcWqOhLsI
— UoAEpidemiology (@UoAEpi) June 17, 2024WONDERFUL WEDNESDAY: The #UKARStudy team are delighted to open another site for #participant recruitment to the @BSACandJAC UK Antimicrobial Registry. Today we welcome our 6th Scottish site @JubileeHospital with PI @thorburn_fiona. We’re looking forward to working with you#AMR pic.twitter.com/DHWNcv6EaP
— UoAEpidemiology (@UoAEpi) June 12, 2024THRILLING THURSDAY: The #UKARStudy team are delighted to open another TWO site for #participant recruitment to the @BSACandJAC UK Antimicrobial Registry. Today we welcome @DarentValleyHsp and @RUHBath We’re looking forward to working with you#AMR #getinvolvedinresearch pic.twitter.com/DnbQRPsd5J
— UoAEpidemiology (@UoAEpi) June 6, 2024FANTASTIC FRIDAY: The #UKARStudy team are delighted to open another site for #participant recruitment to the @BSACandJAC UK Antimicrobial Registry. Today we welcome @PHU_NHS. We’re looking forward to working with you#AMR #getinvolvedinresearch #antimicrobialresistance pic.twitter.com/hCHWUagecN
— UoAEpidemiology (@UoAEpi) May 31, 2024A massive thank you and congratulations to the #UKARStudy team @KetteringHosp for reaching their participant recruitment target to the @BSACandJAC #AMR registry. We're also very grateful that you have agreed to continue participant recruitment to the study #getinvolvedinresearch pic.twitter.com/RfF68QNcU8
— UoAEpidemiology (@UoAEpi) May 30, 2024MAGIC MONDAY: The #UKARStudy team are delighted to open another site for #participant recruitment to the @BSACandJAC UK Antimicrobial Registry. Today we welcome @SwanseabayNHS @PharmacySBU Croeso & diolch, we’re looking forward to working with you#AMR #getinvolvedinresearch pic.twitter.com/mr7CUMtrdo
— UoAEpidemiology (@UoAEpi) May 27, 2024The team at #BSACSpring2024 https://t.co/WlzpnAMytS
— UoAEpidemiology (@UoAEpi) May 16, 2024THANKFUL THURSDAY: The #UKARStudy team are delighted to open 2 more sites for #participant recruitment to the @BSACandJAC UK Antimicrobial Registry this week. Welcome to @RoyalDevonNHS and @DudleyGroupNHS. We’re looking forward to working with you https://t.co/E8TH24x4B9 pic.twitter.com/tQlnbO2lFt
— UoAEpidemiology (@UoAEpi) May 2, 2024Since the Nov 2023 publication the @BSACandJAC #UKARStudy now has 226 participants recruited by the 28 recruiting centres across all 4 devolved nations of the UK. To learn more and to #getinvolvedinresearch follow the link: https://t.co/E8TH24x4B9 #AMR #AntimicrobialResistance https://t.co/QZj2rzdOej
— UoAEpidemiology (@UoAEpi) April 22, 2024Wonderful Wednesday: The #UKARStudy team is delighted to welcome Sandwell & West Birmingham NHS Trust @SWBHnhs @SWBH_RandD as a recruiting centre for the @BSACandJAC UK Antimicrobial Registry. We’re looking forward to working with you. #AntimicrobialResistance #AMR #getinvolved pic.twitter.com/lL8Ai6BbPn
— UoAEpidemiology (@UoAEpi) April 3, 2024The @BSACandJAC #UKARStudy team are virtually attending the #ARUTI Living with Chronic and Complex UTIs conference today, to learn about the importance of #AMR research for people affected by #AntimicrobialResistance #silentpandemic #getinvolvedinresearch https://t.co/Eb0lzMS3Z9
— UoAEpidemiology (@UoAEpi) March 21, 2024FANTASTIC FRIDAY: The #UKARStudy team are delighted to open 2 more sites for #participant recruitment to the @BSACandJAC UK Antimicrobial Registry this week. Welcome to @ChelwestFT @WestMidHospital and Croeso & diolch to @AneurinBevanUHB We’re looking forward to working with you. pic.twitter.com/lymUzyvneT
— UoAEpidemiology (@UoAEpi) March 15, 2024Wonderful Wednesday news: The #UKARStudy team is delighted to welcome @MidYorkshireNHS as our 25th recruiting centre for the @BSACandJAC UK Antimicrobial Registry. We’re looking forward to working with you. #AntimicrobialResistance #getinvolvedinresearch https://t.co/uEonz4U5tx pic.twitter.com/pC7dzvHKoZ
— UoAEpidemiology (@UoAEpi) March 6, 2024Milestone Alert! @NHSGrampian have recruited 50 participants to the @BSACandJAC #UKARStudy - 50% of their target. Many thanks to @Micro_tweeter and the team. UKAR: The secrets of successful study site - The British Society for Antimicrobial Chemotherapy (https://t.co/32Qi6cMrW1)
— UoAEpidemiology (@UoAEpi) March 5, 2024The #UKARStudy team is delighted to welcome @NorthumbriaNHS as a recruiting centre for the @BSACandJAC UK Antimicrobial Registry. We're looking forward to working with you. More here: https://t.co/Eb0lzMS3Z9 #AntimicrobialResistance #getinvolvedinresearch; https://t.co/FZA7A4pAsI
— UoAEpidemiology (@UoAEpi) February 29, 2024The #UKARStudy team is delighted to welcome @HullHospitals as a recruiting centre for the @BSACandJAC UK Antimicrobial Registry. We are looking forward to working with you. More here: https://t.co/Eb0lzMSBOH #AntimicrobialResistance #getinvolvedinresearch; https://t.co/FZA7A4pAsI
— UoAEpidemiology (@UoAEpi) February 23, 2024The UKAR team would like to thank @NHSNotts @NHSGrampian @ImperialNHS @RoyalPapworth @CV_UHB for attending our monthly study drop in session. We value your feedback and hope to see you all again at our next session on 20th March! pic.twitter.com/V0aa1QS53H
— UoAEpidemiology (@UoAEpi) February 21, 2024The #UKARStudy team is delighted to welcome @LivHospitals as a recruiting centre for the @BSACandJAC UK Antimicrobial Registry. We are looking forward to working with you. Learn more: https://t.co/Eb0lzMS3Z9 #AntimicrobialResistance #getinvolvedinresearch https://t.co/FZA7A4pAsI
— UoAEpidemiology (@UoAEpi) February 14, 2024Fantastic Friday - The #UKARStudy team is delighted to welcome 2 new sites @WalsallHcareNHS and @LandDHospital @bedfordhospital to the @BSACandJAC UK Antimicrobial Registry. This comes on the back of our top recruiting week to date; 11 new people bringing us to 133 participants
— UoAEpidemiology (@UoAEpi) February 9, 2024The #UKARStudy team is delighted to welcome @CV_UHB as a recruiting centre for the @BSACandJAC UK Antimicrobial Registry. Croeso & diolch! We are looking forward to working with you. Learn more here https://t.co/Eb0lzMS3Z9 #AntimicrobialResistance #getinvolvedinresearch pic.twitter.com/VdMAyU3mU5
— UoAEpidemiology (@UoAEpi) February 6, 2024Fantastic Friday - The #UKARStudy team is delighted to welcome @NHSForthValley as a recruiting centre for the @BSACandJAC UK Antimicrobial Registry. We are looking forward to working with you. Learn more here https://t.co/Eb0lzMS3Z9 #AntimicrobialResistance #getinvolvedinresearch
— UoAEpidemiology (@UoAEpi) February 2, 2024#UKARStudy team are delighted to welcome @ImperialNHSas as a recruiting centre for the@BSACandJAC UK Antimicrobial Registry Study. We look forward to working with you #AntimicrobialResistance #AMR #getinvolvedinresearch pic.twitter.com/K7ROFz4FKh
— UoAEpidemiology (@UoAEpi) January 17, 2024The @BSACandJAC #UKARStudy is registered with the @NIHRresearch Associate Principal Investigator (API) scheme. Learn more about the study, the scheme, and hear from @corrinea5h about the her experience of being an API @Leic_hospital:https://t.co/1s2wthu4jw #getinvolvedinresearch
— UoAEpidemiology (@UoAEpi) January 10, 2024The UK Antimicrobial Registry has recruited is 100th study participant.
— Gareth Jones (@hteraG_senoJ) January 11, 2024
Massive thanks and well done to the study team, and all staff at recruiting centres.
And now ... onwards and upwards.https://t.co/SoUVuWl3ik@BSACandJAC @jacquisneddons @UoAEpi @AberdeenEpi #UKARstudyThe @BSACandJAC #UKARStudy is registered with the @NIHRresearch Associate Principal Investigator (API) scheme. Learn more about the study, the scheme, and hear from @corrinea5h about the her experience of being an API @Leic_hospital:https://t.co/1s2wthu4jw #getinvolvedinresearch
— UoAEpidemiology (@UoAEpi) January 10, 2024Thanks to all the hard work at our research sites, the #UKARStudy recruited 21 new participants over December making last month a new record for the number of participants recruited in a single month!
— UoAEpidemiology (@UoAEpi) January 8, 2024Fantastic Friday - the #UKARStudy team are delighted to open NHS Lothian for recruitment of participants to the @BSACandJAC study, with @NIHRresearch APIs @amw_chung and @AnnaCTGordon pic.twitter.com/OdoYnNFtER
— UoAEpidemiology (@UoAEpi) December 15, 2023The #UKARStudy team is delighted to welcome @nhsuhcw as a recruiting centre for the @BSACandJAC UK Antimicrobial Registry. We are looking forward to working with you. #AntimicrobialResistance #AMR #getinvolvedinresearch pic.twitter.com/oPreyc76yE
— UoAEpidemiology (@UoAEpi) December 7, 2023The #UKARStudy team is delighted to welcome @uhbtrust as a recruiting centre for the @BSACandJAC UK Antimicrobial Registry. We are looking forward to working with you. #AntimicrobialResistance #AMR #getinvolvedinresearch pic.twitter.com/kbmMMCzKcf
— UoAEpidemiology (@UoAEpi) December 5, 2023The #UKARStudy team is delighted to welcome @NCICNHS as a recruiting centre for the @BSACandJAC UK Antimicrobial Registry. We are looking forward to working with you. #AntimicrobialResistance #AMR #getinvolvedinresearch pic.twitter.com/nQevRUvrix
— UoAEpidemiology (@UoAEpi) November 28, 2023The Epi Group all #goblueforAMR during #WAAW2023 whilst listening to a thoroughly thought-provoking talk by @Adam_Mart1n of @AUHE_Leeds pic.twitter.com/INZ8AqZDEJ
— UoAEpidemiology (@UoAEpi) November 22, 2023The @BSACandJAC @UoAEpi #UKARStudy site team @SouthernHSCT kick off #WAAW2023 and #GoBlueforAMR to promote Preventing Antimicrobial Resistance Together. #teamSHSCT #AMR #AntimicrobialResistance https://t.co/ffqiFkKc3Z pic.twitter.com/kSo8vxAksP
— rebecca parr (@reb_parr) November 18, 2023Calling all #UKARStudy site teams across the UK. Join the #UKARStudy office team, embrace #WAAW2023, share the message and share your #goblueforAMR site study team photos. #AMR #AntimicrobialResistance https://t.co/6dJyXHc7cn pic.twitter.com/865FCKun9k
— UoAEpidemiology (@UoAEpi) November 20, 2023It has been a fantastic week for the #UKARStudy as we have been able to open 3 more sites for recruitment of participants to the @BSACandJAC UK Antimicrobial Registry. Many thanks to @NHSTayside @RoyalPapworth and @NHSNotts. We're looking forward to working with you. #AMR
— UoAEpidemiology (@UoAEpi) November 16, 2023The #UKARStudy team are very happy to open recruitment at 2 more UK hospital sites to the #antimicrobial @BSACandJAC registry. Welcome and thank you for coming onboard @NHSSussex and @SouthTees #JamesCookHospital #AntimicrobialResistance #AMR #getinvolvedinresearch pic.twitter.com/MGwq2pfH2l
— UoAEpidemiology (@UoAEpi) November 13, 2023The #UKARStudy team are delighted to announce that we are open to recruitment to the @BSACandJAC #antimicrobialresistance study in Northern Ireland as today we Green Light @SouthernHSCT. Many thanks to @NICRNCoordCentr, @angelboulosxo and all the team. #AMR #getinvolvedinresearch https://t.co/ofn34BtnAJ pic.twitter.com/qmaaikFA7T
— UoAEpidemiology (@UoAEpi) September 28, 2023FANTASTIC NEWS! The #UKARStudy team are delighted to welcome @MFTnhs and #Pharmacist PI @francesgarragh1 to the @BSACandJAC UK Antimicrobial Registry. We look forward to working with you as we move toward a better understanding of #antimicrobialresistance. https://t.co/4HxE4GOw9G
— UoAEpidemiology (@UoAEpi) September 15, 2023First Recruit Friday! The #UKARStudy are delighted to have our first recruit @Leic_hospital. Thank you to the team, PI David Jenkins @NatalieAyton & @corrinea5h. To learn more about how to #getinvolved in the @BSACandJAC study follow the link #AMR https://t.co/4HxE4GOw9G
— UoAEpidemiology (@UoAEpi) September 8, 2023The #UKARStudy is looking forward to working with @AnnaCTGordon of @NHS_Lothian who has registered with the @NIHRresearch Associate Principal Investigator scheme @NIHRcommunity. The scheme is a great way to #getinvolvedinresearch and develop your clinical research career. #AMR https://t.co/n2ZvkBbZnK
— UoAEpidemiology (@UoAEpi) August 24, 2023Great article from @BSACandJAC featuring the #UKARStudy, which represents an opportunity for pharmacists to #getinvolvedinresearch as Principal Investigators and @NIHRcommunity Associate Principal Investigators on an observational study looking into #AMRhttps://t.co/k40f100Bzg
— UoAEpidemiology (@UoAEpi) August 22, 2023Exciting News! Join us in celebrating a groundbreaking moment for #UKAR_Study & @UoAEpi! Thrilled to announce @southernHSCT as the FIRST site in Northern Ireland to join in almost 20 years of studies. #HealthResearch #NI #Milestone @BSACandJAC Thanks to everyone involved! https://t.co/wziu0Fvy0f
— UoAEpidemiology (@UoAEpi) August 9, 2023Want to get involved in research?#nihr #AssociatePI scheme. The UKAR Study provides a great training opportunity. Work alongside the Local PI on an NIHR portfolio study, find out more here: https://t.co/tp8pauPIXs.
— UoAEpidemiology (@UoAEpi) August 2, 2023
Welcome to our newest #NIHR #AssociatePI @corrinea5h #UKARStudy pic.twitter.com/kQI7yUCQ48Fantastic to see the #UKARStudy on https://t.co/7umPF2XpXO. Thank you to the team @ResearchAwaren1. Coincidentally, today we have our first participant @NHSGrampian Many thanks to PI @Micro_tweeter and the UKAR Study team. #AMR #antimicrobialresistance #getinvolvedinresearch https://t.co/smAevD058O
— UoAEpidemiology (@UoAEpi) July 20, 2023Are you interested in antimicrobial resistance?
— UoAEpidemiology (@UoAEpi) July 13, 2023
Do you want to be involved in UK-wide research into the effective use of new-to-market antibiotics?
The UK Antimicrobial Registry would like to hear from you. Learn more https://t.co/XC2SwFJUef @BSACandJAC#UKARStudy #AMR pic.twitter.com/aLUnLJ90Y8Great news! Green Light Day for the #UKARStudy and Royal Cornwall Hospitals Trust @RCHTWeCare @neilthepcist We look forward to working with you on the UK Antimicrobial Registry Study @BSACandJAC#UKARStudy #AMR #antimicrobialresistance #antimicrobialstewardship pic.twitter.com/g2dBT0KL1K
— UoAEpidemiology (@UoAEpi) July 11, 2023Congratulations to @KettGeneral for recruiting their first #UKARStudy participant. It only took 4 days from #GreenLight to recruit #1. Many thanks to the site study team for a great job. #AMR #AntimicrobialResistance #antimicrobialstewardship #getinvolvedinresearch @BSACandJAC pic.twitter.com/cJIb6phYn2
— UoAEpidemiology (@UoAEpi) July 4, 2023FANTASTIC NEWS! Green Light Day for the #UKARStudy and @KettGeneral Thank you to PI Ryan Hamilton and all the team – you guys are worthy of a ROSE Award. Looking forward to working together @BSACandJAC #AMR #antimicrobialresistance #antimicrobialstewardship #getinvolvedinresearch pic.twitter.com/klO4EPXiJ3
— UoAEpidemiology (@UoAEpi) June 30, 2023Fantastic Friday update - @NHSGGC have recruited 3 more participants to the #UKARStudy study this week. Many thanks to everyone involved; @raseaton66 you have a great team. #getinvolvedinresearch #antimicrobialresistance #AMR pic.twitter.com/UxoroxvJNw
— UoAEpidemiology (@UoAEpi) June 23, 2023The #UKARStudy is registered for the NIHR Associate PI scheme @NIHRcommunity. To find out how trainees in your NHS trust/board can be included, please email the team (ukar@abdn.ac.uk) and visit the link #getinvolvedinresearch #AMR #antimicrobialresistance https://t.co/iNXytbrGhf
— UoAEpidemiology (@UoAEpi) June 19, 2023Today the #UKARStudy team says goodbye to "Flemmy"! Many thanks to all the delegates from the @BSACandJAC Spring Conference that entered the "Guess the Antibiotic Emoji" quiz. All entrants got full marksCongrats to @Vaitehi who was the lucky winner to be pulled out of the#AMR pic.twitter.com/D2n5siYxZ8
— UoAEpidemiology (@UoAEpi) June 14, 2023GREAT NEWS! Green Light Day for the #UKARStudy and @NHSGGC. Today we are happy give the Green Light to PI @raseaton66 and the team at NHS Greater Glasgow and Clyde to start recruiting participants to the @BSACandJAC #UKARStudy. #AMR #antimicrobialresistance #getinvolvedinresearch pic.twitter.com/6c8AyF0fbk
— UoAEpidemiology (@UoAEpi) May 23, 2023BIG NEWS! Green Light Day for the #UKARStudy and @NHSGrampian. Today we are happy to Green Light NHS Grampian and our PI @Micro_tweeter to start recruiting participants to the @BSACandJAC #UKARStudy. #AMR #antimicrobialresistance #antimicrobialstewardship #getinvolvedinresearch pic.twitter.com/o8xMw1e1Of
— UoAEpidemiology (@UoAEpi) May 19, 2023Are you a clinician who's passionate about tackling #AMR? If you're at the #BSACSpring2023 today, come and have a chat with the excellent @UoAEpi #UKARStudy team to discuss how you can get involved with the UK Antimicrobial Registry. https://t.co/ujZ6nAYkzF pic.twitter.com/Cpf3E0YrgM
— BSAC (@BSACandJAC) May 18, 2023Group members @hteraG_senoJ, Laura Moir and @reb_parr are in London today to represent the#UKARStudy team at #BSACSpring2023 with the latest from the @BSACandJAC
— UoAEpidemiology (@UoAEpi) May 18, 2023
UK Antimicrobial Registry #AntimicrobialResistance #AMR - pop along and say hello if you're in attendance! https://t.co/wbbPIVEcLXIndeed! For more about the UKAR, visit https://t.co/oddTcTrp6p. https://t.co/345mMiyvMp
— UoAEpidemiology (@UoAEpi) May 3, 2023Great to watch @jacquisneddons of @BSACandJAC discussing the importance of the #UKARStudy. For more information visit the UKAR Study websites at https://t.co/E8TH24xCqH and https://t.co/FZA7A4q8ig #AntimicrobialResistance #AMR https://t.co/EcU6lRgK0o
— UoAEpidemiology (@UoAEpi) May 4, 2023 - Why is this research important?
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Antibiotics are a vital part of modern medicine as they stop the growth of bacteria that cause infection. The UKAR Study will help us look how widely these medicines are used across the UK, why they are being prescribed, and how effective they are.
Bacteria are becoming resistant to treatment with commonly used antibiotics. This means that it is becoming difficult to successfully treat some bacterial infections. It is estimated that, worldwide, deaths due to antimicrobial resistance are on the same scale as deaths due to major diseases such as HIV/AIDS and malaria (Lancet, 2022: Global burden of bacterial antimicrobial resistance in 2019: a systematic analysis).
Links to Resources about AMR / antibiotics:
(206) The Evolution of Bacteria on a “Mega-Plate” Petri Dish (Kishony Lab) - YouTube
Antimicrobial resistance (who.int)
Stewardship & Surveillance - The British Society for Antimicrobial Chemotherapy (bsac.org.uk)
- What will this research involve?
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We will ask that patients give us their consent to allow us access to their medical records and allow us to collect clinical data from their notes. No further participation is required, as the study does not include any participant surveys or questionnaires.
Clinical data will be collected during treatment with the antibiotics included in the study, and then at 28 days, 6 months, and 12 months afterwards. We will collect information about the infections that the antibiotics are being used to treat, why these antibiotics were chosen and how effective they are at treating the infection.
The antibiotics included in the study are listed below:
Cefiderocol Ceftaroline
Ceftazidime/avibactam Ceftobiprole
Ceftolozane/tazobactam Dalbavancin
Eravacycline Delafloxacin
Imipenem/cilastatin/relebactam Oritavancin
Meropenem/vaborbactam
All of the information that we collect will be analysed so that we can better understand how effective the antibiotics are at treating infections and tackling antimicrobial resistance. Participants will not be identifiable in any of the findings published from this research.
UKAR Site Flyer
Download link: UKAR Flyer ver 1.png
- Who can take part in the study?
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To be included in the UKAR Study, a patient must be 18 years old or older, and have been prescribed one of the 11 study antibiotics during their current stay in a participating hospital:
Cefiderocol Ceftaroline
Ceftazidime/avibactam Ceftobiprole
Ceftolozane/tazobactam Dalbavancin
Eravacycline Delafloxacin
Imipenem/cilastatin/relebactam Oritavancin
Meropenem/vaborbactam
The drug must have been prescribed within the last 60 days and the patient must have been treated with the drug for at least 24 hours.
As we are collecting health information, the study will ask for informed consent from patients. If a patient does not have the capacity to consent for themselves, an appropriate person will be asked to act on behalf of the patient.
If you have any questions about who can take part in the study, please email the UKAR Study team: ukar@abdn.ac.uk
- How will the research benefit patients and society?
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Being part of the UKAR Study does not affect the treatment that a patient receives. Therefore, individual patients do not directly benefit from participating in the study. However, the UKAR Study will provide important information about the study drugs. The study will help us see how often these drugs are used across the UK, and to look at how safe and effective they are. Lessons learnt from the registry will help doctors across the country decide how best to treat patients in the future.
- FAQs
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What is required of a participant in the UKAR Study?
We will ask the patient to give their consent for us to access their hospital notes. We will not ask anything further from the patient, as there are no participant surveys or questionnaires.
How will my information be used?
No personal or identifiable information about participants in the UKAR Study will be available to anyone outside of the UKAR Study team. Personal, identifiable information will be removed from the data before it is analysed.
Which drugs are included in the UKAR Study?
Gram negative agents: Gram positive agents:
Cefiderocol Ceftaroline
Ceftazidime/avibactam Ceftobiprole
Ceftolozane/tazobactam Dalbavancin
Eravacycline Delafloxacin
Imipenem/cilastatin/relebactam Oritavancin
Meropenem/vaborbactam
How many participants does a site need to recruit?
A site will need to recruit a minimum of 20 patients over the course of the study, which is expected to be recruiting participants through to May 2026
How does my site become involved in the study?
To get involved in the UKAR Study, please complete the UKAR Expression of Interest (EOI) form which can be accessed from on the website or using the QR code:
https://forms.office.com/UKAR-EOI
What are the requirements of my site?
- Prescription of the any of the antibiotics included in the study.
- A way to identify patients who are prescribed antibiotics included in the study.
- Someone able to receive informed consent from participants.
- A Principal Investigator to take responsibility for running the UKAR Study at site.
The UKAR Study is registered with the NIHR Associate PI scheme - Associate Principal Investigator Scheme
Fran Garraghan @francesgarragh1, Consultant Pharmacist & Antibiotic angel, is the UKAR Study Principal Investigator at Manchester University NHS Foundation Trust. Fran has made this video about setting up the study at site.
- How can I get involved?
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If you are interested to learn more about the UKAR Study, please follow the below links to our Expression of Interest form, or contact the team; ukar@abdn.ac.uk
https://forms.office.com/UKAR-EOI
- Study team
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The following team will be responsible for delivering the study:
Professor Gary Macfarlane - Chief investigator – UKAR Virtual Registry
Professor Gareth Jones – Chief Investigator – UKAR Hospital Registry
Mrs Laura Moir – Study Coordinator
Dr Rebecca Parr – Assistant Study Coordinator
Mr Jay Woods – Project Assistant
- Who is funding this study?
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The UKAR Study is funded by The British Society for Antimicrobial Chemotherapy
To find out more visit Home - UK Antimicrobial Registry (bsac-ukar.org)
- What we have found so far
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Articles
You can view the main articles for the UKAR study here.
P15 UK Antimicrobial Registry Study: progress to date
UKAR Poster - BSAC 2024 Spring Conference (16th to 17th May)
Download Link: UKARposterBSACSC_08-Apr-2024.pptx
UKAR Poster - BSAC 2023 Winter Conference (30th November to 1st December)
Download Link: UKARposterBSACWC_27-Nov-2023.pptx
- Patient Stories
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If you are a patient involved in the UKAR study and would like to share your experiences, please complete the short questionnaire by clicking on this link.
You can also contact us at ukar@abdn.ac.uk
- Contact details
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If you are interested to learn more about the UKAR Study, please contact the team; ukar@abdn.ac.uk
- Glossary
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Chemotherapy – The use of chemicals (drugs) as therapy (treatment) against disease.
Microbe – a microorganism (such as bacteria) that can only be seen using a microscope.
Antimicrobial – Something (a drug) that works against microbes (such as bacteria).
Antimicrobial resistance – Microbes (such as bacteria) that have developed the ability to survive treatment with antimicrobial drugs (such as antibiotics).