Trial Manager
Seonaidh Cotton joined HSRU in 2007 as a trial manager. She graduated from the University of Aberdeen with a BSc in Health Sciences in 1993, an MLitt in 1995, and a PhD in 2007. Prior to joining the Unit, Seonaidh worked in the Department of Public Health at the University of Aberdeen.
Seonaidh is the Deputy Senior Trial Manager within CHaRT. Seonaidh works as a trial manager across a number of CHaRT trials, including BICS, TWICS and CLASS. She has previously been trial manager for NIAMI, FOCCUS, REFLUX and the Cysteamine in CF study. Seonaidh is the senior trial manager on a number of trials, including RAACENO, EMPOWER, ELECTRIC and ALLEGRO.
Seonaidh is interested in methodological research that can be carried out alongside existing trials, including the provision of information to potential participants, strategies to increase response rates and whether it is possible to predict which recruitment sites will perform well.
Seonaidh works across a number of trials. These include
BICS - a multicentre trial investigating the effectiveness of thel beta-blocker bisoprolol in preventing exacerbations of chronic obstructive pulmonary disease;
CLASS - a multicentre trial comparing foam sclerotherapy and endovenous laser ablation with conventional surgery in patients with varicose veins;
TWICS - a multicentre trial investigating the effectiveness of low dose oral theophylline as an adjunct to inhaled corticosteroids in preventing exacerbations of chronic obstructive pulmonary disease.
Seonaidh is the senior trial manager on RAACENO, EMPOWER, ELECTRIC and ALLEGRO. Seonaidh is also interested in methodological research that can be carried out alongside existing trials, including the provision of information to potential participants and strategies to increase response rates.
She previously worked on a number of trials that have now been completed.
NIAMI - a phase II multicentre trial investigating whether an intravenous injection of sodium nitrite given immediately before the infarct related artery is opened reduces ischaemia reperfusion injury in patients with myocardial infarction;
FOCCUS - a pragmatic multi-centred randomised controlled trial of surgical HDU care versus HDU care delivered in an ICU and pre-operative fluid loading in high-risk patients undergoing major elective surgery
REFLUX - a multi-centre randomised trial comparing a policy of relatively early laparoscopic surgery with a continued best medical management policy for people with more severe gastro-oesophageal reflux disease.
The Cysteamine in CF study - a single-centre, single group open label study of oral cysteamine in patients with Cystic Fibrosis.
Seonaidh contributes to the following courses: PU5003 Health Service Research MSc course; MT5515 Basic Research Methods; PU5504 Public Health Nutrition; and ME40FM Foundations of Medical Research.
She has supervised a number of undergraduate and Masters level research projects, including topics such as provision of information to potential participants, strategies to increase response rates, and outcome measures.
Outwith the University, Seonaidh is a faculty member on the Edinburgh Clinical Trial Management Course (ECTMC).
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The New England Journal of Medicine, vol. 381, no. 10, pp. 912-922
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Health technology assessment (Winchester, England), vol. 23, no. 37, pp. 1-146
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