Director (CHaRT)
- About
-
- Email Address
- g.maclennan@abdn.ac.uk
- Telephone Number
- +44 (0)1224 438147
- Office Address
Health Services Research Unit
2nd Floor Health Sciences Building
Foresterhill
Aberdeen
AB25 2ZD- School/Department
- School of Medicine, Medical Sciences and Nutrition
Biography
I am currently Professor of Medical Statistics and the Director of the Centre for Health Care Randomised Trials (CHaRT) which is the Clinical Trials Unit embedded within the Health Services Research Unit. My overarching research interest is in designing fair tests of health care treatments and policies, with a specifc interest in evaluating surgical and complex interventions. I'm also interested in improving the design, conduct, and analysis and reporting of clinical trials through the development and application of methodological research to clinical trials from CHaRT.
My undergrad degree is in Mathematics from the University of Aberdeen, graduating in 1997. After a year training as a Mathematics teacher I joined the Unit in September 1998 as a statistician. I studied part-time for an MSc in Applied Statistics with Sheffield Hallam University, graduating in 2004. In 2008 I was appointed Senior Statistican, and in 2016 was I Interim Programme Director for the Health Care Assessment Programme, until being appointment as CHaRT Director in April 2017.
Qualifications
- BSc Mathematics1997 - University of Aberdeen
- MSc Applied Statistics2004 - Sheffield Hallam University
- Research
-
Research Overview
The application of statistical methods to clinical trials. Recent example is JCE paper available here on using instrumental variables in a surgery trial to address non-compliance. Collaborators were Jonathan Cook (Oxford), Tom Palmer (Lancaster), and Richard Emesley (Manchester).
Research on making trials more efficient, collaborating with Trial Forge.
Current Research
A complete list of the CHaRT RCT portolio is available by clicking here
- Teaching
-
Teaching Responsibilities
I teach on our MPH course module PU5031: EVIDENCE-BASED HEALTH.
- Publications
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Page 4 of 5 Results 151 to 200 of 227
Effect of day and time of admission on mortality in an intensive care unit
Journal of the Intensive Care Society, vol. 14, no. 4, pp. 294-298Contributions to Journals: Articles- [ONLINE] DOI: https://doi.org/10.1177/175114371301400405
- [ONLINE] View publication in Scopus
Management of the open abdomen: A national study of clinical outcome and safety of negative pressure wound therapy
Annals of Surgery, vol. 257, no. 6, pp. 1154-1159Contributions to Journals: Articles- [ONLINE] DOI: https://doi.org/10.1097/SLA.0b013e31828b8bc8
- [ONLINE] View publication in Scopus
Authors' reply - Assessing catheter-associated urinary tract infection
The Lancet, vol. 381, no. 9877, pp. 1536Contributions to Journals: Letters- [ONLINE] DOI: https://doi.org/10.1016/S0140-6736(13)60974-5
- [ONLINE] View publication in Scopus
Protocol: does sodium nitrite administration reduce ischaemia-reperfusion injury in patients presenting with acute ST segment elevation myocardial infarction? Nitrites in acute myocardial infarction (NIAMI)
Journal of translational medicine, vol. 11, 116Contributions to Journals: Articles- [ONLINE] DOI: https://doi.org/10.1186/1479-5876-11-116
- [OPEN ACCESS] http://aura.abdn.ac.uk/bitstream/2164/3089/1/Siddiqi_2013.pdf
Mortality and quality of life in the five years after severe sepsis
Critical Care, vol. 17, no. 2, R70Contributions to Journals: Articles- [ONLINE] DOI: https://doi.org/10.1186/cc12616
- [OPEN ACCESS] http://aura.abdn.ac.uk/bitstream/2164/3311/1/Cuthbertson_2013.pdf
Five-year results of a randomised controlled trial comparing mobile and fixed bearings in total knee replacement
Journal of Bone & Joint Surgery (US Volume), vol. 95-B, no. 4, pp. 486-492Contributions to Journals: Articles- [ONLINE] DOI: https://doi.org/10.1302/0301-620X.95B4.29454
Antimicrobial catheters for reduction of symptomatic urinary tract infection in adults requiring short-term catheterisation in hospital: a multicentre randomised controlled trial
The Lancet, vol. 380, no. 9857, pp. 1927-1935Contributions to Journals: Articles- [ONLINE] DOI: https://doi.org/10.1016/S0140-6736(12)61380-4
- [OPEN ACCESS] http://aura.abdn.ac.uk/bitstream/2164/2745/1/Pickard_2012.pdf
Systematic review of perioperative and quality-of-life outcomes following surgical management of localised renal cancer
European Urology, vol. 62, no. 6, pp. 1097-1117Contributions to Journals: Articles- [ONLINE] DOI: https://doi.org/10.1016/j.eururo.2012.07.028
- [OPEN ACCESS] http://aura.abdn.ac.uk/bitstream/2164/2588/1/MacLennan_2013.pdf
Types of urethral catheter for reducing symptomatic urinary tract infections in hospitalised adults requiring short-term catheterisation: multicentre randomised controlled trial and economic evaluation of antimicrobial- and antiseptic-impregnated urethral catheters (the CATHETER trial)
Health Technology Assessment, vol. 16, no. 47, pp. 1-197Contributions to Journals: Articles- [ONLINE] DOI: https://doi.org/10.3310/hta16470
- [OPEN ACCESS] http://aura.abdn.ac.uk/bitstream/2164/2744/1/Pickard_2012.pdf
Explaining clinical behaviors using multiple theoretical models
Implementation Science, vol. 7, 99Contributions to Journals: Articles- [ONLINE] DOI: https://doi.org/10.1186/1748-5908-7-99
- [OPEN ACCESS] http://aura.abdn.ac.uk/bitstream/2164/2784/1/Eccles_2012.pdf
Using shared goal setting to improve access and equity: a mixed methods study of the Good Goals intervention in children's occupational therapy
Implementation Science, vol. 7, 76Contributions to Journals: Articles- [ONLINE] DOI: https://doi.org/10.1186/1748-5908-7-76
- [OPEN ACCESS] http://aura.abdn.ac.uk/bitstream/2164/2802/1/Kolehmainen_2012.pdf
Do incentives, reminders or reduced burden improve healthcare professional response rates in postal questionnaires?: two randomised controlled trials
BMC Health Services Research, vol. 12, 250Contributions to Journals: Articles- [ONLINE] DOI: https://doi.org/10.1186/1472-6963-12-250
- [OPEN ACCESS] http://aura.abdn.ac.uk/bitstream/2164/2753/1/Glidewell_2012.pdf
Corrigendum to "systematic review of oncological outcomes following surgical management of localised renal cancer" [Eur Urol 2012;61:972-93]
European Urology, vol. 62, no. 1Contributions to Journals: Comments and Debates- [ONLINE] DOI: https://doi.org/10.1016/j.eururo.2012.04.003
- [ONLINE] View publication in Scopus
E-mail invitations to general practitioners were as effective as postal invitations and were more efficient
Journal of Clinical Epidemiology, vol. 65, no. 7, pp. 793-797Contributions to Journals: Articles- [ONLINE] DOI: https://doi.org/10.1016/j.jclinepi.2011.11.010
- [OPEN ACCESS] http://aura.abdn.ac.uk/bitstream/2164/2807/1/Treweek_2012.pdf
Systematic review of oncological outcomes following surgical management of localised renal cancer
European Urology, vol. 61, no. 5, pp. 972-993Contributions to Journals: Articles- [ONLINE] DOI: https://doi.org/10.1016/j.eururo.2012.02.039
- [OPEN ACCESS] http://aura.abdn.ac.uk/bitstream/2164/2550/1/MacLennan_2012.pdf
Long-term follow-up for mortality and cancer in a randomized placebo-controlled trial of vitamin D3 and/or calcium (RECORD trial)
Journal of Clinical Endocrinology and Metabolism, vol. 97, no. 2, pp. 614-622Contributions to Journals: Articles- [ONLINE] DOI: https://doi.org/10.1210/jc.2011-1309
- [OPEN ACCESS] http://aura.abdn.ac.uk/bitstream/2164/2671/1/Avenell_2011.pdf
Rationing of total knee replacement: a cost-effectiveness analysis on a large trial data set
BMJ Open, vol. 2, no. 1, e000332Contributions to Journals: Articles- [ONLINE] DOI: https://doi.org/10.1136/bmjopen-2011-000332
- [OPEN ACCESS] http://aura.abdn.ac.uk/bitstream/2164/2765/1/BMJ_Open_2012_Dakin_.pdf
Clustering in surgical trials: database of intracluster correlations
Trials, vol. 13, no. -, 2Contributions to Journals: Articles- [ONLINE] DOI: https://doi.org/10.1186/1745-6215-13-2
- [OPEN ACCESS] http://aura.abdn.ac.uk/bitstream/2164/2469/1/Cook_2012.pdf
- [ONLINE] View publication in Scopus
Identifying active ingredients in complex behavioural interventions for obese adults with obesity-related co-morbidities or additional risk factors for co-morbidities: a systematic review
Health Psychology Review, vol. 6, no. 1, pp. 7-32Contributions to Journals: Articles- [ONLINE] DOI: https://doi.org/10.1080/17437199.2010.513298
- [OPEN ACCESS] http://aura.abdn.ac.uk/bitstream/2164/2808/1/Dombrowski_2010.pdf
Process evaluation for the FEeding Support Team (FEST) randomised controlled feasibility trial of proactive and reactive telephone support for breastfeeding women living in disadvantaged areas
BMJ Open, vol. 2, no. 2, e001039Contributions to Journals: Articles- [ONLINE] DOI: https://doi.org/10.1136/bmjopen-2012-001039
- [OPEN ACCESS] http://aura.abdn.ac.uk/bitstream/2164/2475/1/Hoddinott_2012.pdf
The FEeding Support Team (FEST) randomised, controlled feasibility trial of proactive and reactive telephone support for breastfeeding women living in disadvantaged areas
BMJ Open, vol. 2, no. 2, e000652Contributions to Journals: Articles- [ONLINE] DOI: https://doi.org/10.1136/bmjopen-2011-000652
- [OPEN ACCESS] http://aura.abdn.ac.uk/bitstream/2164/2476/1/Hoddinott_2012.pdf
Surveillance mammography for detecting ipsilateral breast tumour recurrence and metachronous contralateral breast cancer: a systematic review
European Radiology, vol. 21, no. 12, pp. 2484-2491Contributions to Journals: Articles- [ONLINE] DOI: https://doi.org/10.1007/s00330-011-2226-z
- [OPEN ACCESS] http://aura.abdn.ac.uk/bitstream/2164/2576/1/Robertson_2011.pdf
Assessing risk of bias in non-randomised studies and incorporating GRADE: Initial experience with a new Cochrane ‘risk of bias’ tool under development
Contributions to Conferences: PapersThe hazards of extracting hazard ratios from survival curves for meta-analyses in observational studies
Contributions to Conferences: PapersEvidence for partial nephrectomy
Contributions to Conferences: PapersPatellar resurfacing in total knee replacement: five-year clinical and economic results of a large randomized controlled trial
The Journal of Bone & Joint Surgery. American Volume, vol. 93, no. 16, pp. 1473-1481Contributions to Journals: Articles- [ONLINE] DOI: https://doi.org/10.2106/JBJS.J.00725
- [OPEN ACCESS] http://aura.abdn.ac.uk/bitstream/2164/2477/1/Breeman_2011.pdf
The clinical effectiveness and cost-effectiveness of different surveillance mammography regimens after the treatment for primary breast cancer: systematic reviews registry database analyses and economic evaluation
Health Technology Assessment, vol. 15, no. 34, pp. v-vi, 1-322Contributions to Journals: ArticlesFurther use for the harvest plot: a novel method for quantitative and qualitative data synthesis
Research Synthesis Methods, vol. 2, no. 2, pp. 79-83Contributions to Journals: Articles- [ONLINE] DOI: https://doi.org/10.1002/jrsm.37
Applying psychological theories to evidence-based clinical practice: identifying factors predictive of lumbar spine x-ray for low back pain in UK primary care practice
Implementation Science, vol. 6, pp. 55Contributions to Journals: Articles- [ONLINE] DOI: https://doi.org/10.1186/1748-5908-6-55
- [OPEN ACCESS] http://aura.abdn.ac.uk/bitstream/2164/2394/1/Grimshaw_2011.pdf
Developing and evaluating interventions to reduce inappropriate prescribing by general practitioners of antibiotics for upper respiratory tract infections: a randomised controlled trial to compare paper-based and web-based modelling experiments
Implementation Science, vol. 6, no. 1, pp. 16Contributions to Journals: Articles- [ONLINE] DOI: https://doi.org/10.1186/1748-5908-6-16
- [OPEN ACCESS] http://aura.abdn.ac.uk/bitstream/2164/2656/1/Treweek_2011.pdf
Calcium and heart attacks: Authors' reply
BMJ (Online), vol. 341, no. 7773, pp. 569Contributions to Journals: Letters- [ONLINE] DOI: https://doi.org/10.1136/bmj.c4998
- [ONLINE] View publication in Scopus
Clinicians' caseload management behaviours as explanatory factors in patients' length of time on caseloads: a predictive multilevel study in paediatric community occupational therapy
BMC Health Services Research, vol. 10, no. 249, 249Contributions to Journals: Articles- [ONLINE] DOI: https://doi.org/10.1186/1472-6963-10-249
- [OPEN ACCESS] http://aura.abdn.ac.uk/bitstream/2164/1222/1/Kolehmainen%25202010.pdf
Effect of calcium supplements on risk of myocardial infarction and cardiovascular events: meta-analysis
British Medical Journal, vol. 341, no. -, c3691Contributions to Journals: Articles- [ONLINE] DOI: https://doi.org/10.1136/bmj.c3691
- [OPEN ACCESS] http://aura.abdn.ac.uk/bitstream/2164/756/1/Bolland%25202010.pdf
Study of progesterone for the prevention of preterm birth in twins (STOPPIT): findings from a trial-based cost-effectiveness analysis
International Journal of Technology Assessment in Health Care, vol. 26, no. 2, pp. 141-148Contributions to Journals: Articles- [ONLINE] DOI: https://doi.org/10.1017/S0266462310000930
- [OPEN ACCESS] http://aura.abdn.ac.uk/bitstream/2164/2646/1/MacLennan%25202010.pdf
Applying psychological theories to evidence-based clinical practice: identifying factors predictive of placing preventive fissure sealants
Implementation Science, vol. 5, pp. 25Contributions to Journals: Articles- [ONLINE] DOI: https://doi.org/10.1186/1748-5908-5-25
- [OPEN ACCESS] http://aura.abdn.ac.uk/bitstream/2164/2387/1/Bonetti%25202010.pdf
The clinical effectiveness of transurethral incision of the prostate: a systematic review of randomised controlled trials
World Journal of Urology, vol. 28, no. 1, pp. 23-32Contributions to Journals: Articles- [ONLINE] DOI: https://doi.org/10.1007/s00345-009-0496-8
- [OPEN ACCESS] http://aura.abdn.ac.uk/bitstream/2164/1043/1/Lourenco%25202010.pdf
Quality of life in the five years after intensive care: a cohort study
Critical Care, vol. 14, no. 1, R6Contributions to Journals: Articles- [ONLINE] DOI: https://doi.org/10.1186/cc8848
- [OPEN ACCESS] http://aura.abdn.ac.uk/bitstream/2164/729/1/CuthbertsonCritCare2010.pdf
Factors Influencing the Participation of Older People in Clinical Trials: Data Analysis from the MAVIS Trial
Journal of Nutrition, Health & Aging, vol. 14, no. 1, pp. 51-56Contributions to Journals: Articles- [ONLINE] DOI: https://doi.org/10.1007/s12603-010-0009-x
- [OPEN ACCESS] http://aura.abdn.ac.uk/bitstream/2164/2036/1/Fearn%25202010.pdf
Randomized trial of intensive bisphosphonate treatment versus symptomatic management in Paget's disease of bone
Journal of Bone and Mineral Research, vol. 25, no. 1, pp. 20-31Contributions to Journals: Articles- [ONLINE] DOI: https://doi.org/10.1359/jbmr.090709
Pragmatic multi-centre randomised trial of (1) routine postoperative ICU care and/or (2) pre-operative fluid loading in high-risk surgical patients undergoing major elective and urgent surgery
Edinburgh, United Kingdom: Chief Scientist Office. 7 pagesBooks and Reports: Commissioned ReportsSurveillance following breast cancer: is it cost-effective?
Breast Cancer Research, vol. 12, no. Suppl. 3, pp. 5-6Contributions to Journals: Articles- [ONLINE] DOI: https://doi.org/10.1186/bcr2658
Development and exploratory cluster-randomised opportunistic trial of a theory-based intervention to enhance physical activity among adolescents
Psychology & Health, vol. 24, no. 7, pp. 805-822Contributions to Journals: Articles- [ONLINE] DOI: https://doi.org/10.1080/08870440802040707
- [OPEN ACCESS] http://aura.abdn.ac.uk/bitstream/2164/754/1/Araujo-Soares%25202009.pdf
Vitamin D supplementation and type 2 diabetes: a substudy of a randomised placebo-controlled trial in older people (RECORD trial, ISRCTN 51647438)
Age and Ageing, vol. 38, no. 5, pp. 606-609Contributions to Journals: Articles- [ONLINE] DOI: https://doi.org/10.1093/ageing/afp109
Uric acid levels and outcome from coronary artery bypass grafting
Journal of Thoracic and Cardiovascular Surgery, vol. 138, no. 1, pp. 200-205Contributions to Journals: Articles- [ONLINE] DOI: https://doi.org/10.1016/j.jtcvs.2008.12.052
- [ONLINE] View publication in Scopus
Progesterone for the prevention of preterm birth in twin pregnancy (STOPPIT): a randomised, double-blind, placebo-controlled study and meta-analysis
The Lancet, vol. 373, no. 9680, pp. 2034-2040Contributions to Journals: Articles- [ONLINE] DOI: https://doi.org/10.1016/S0140-6736(09)60947-8
- [OPEN ACCESS] http://aura.abdn.ac.uk/bitstream/2164/2644/1/Norman_2009.pdf
Meaning behind measurement: self-comparisons affect responses to health-related quality of life questionnaires
Quality of Life Research, vol. 18, no. 2, pp. 221-230Contributions to Journals: Articles- [ONLINE] http://aura.abdn.ac.uk/handle/2164/306
- [ONLINE] DOI: https://doi.org/10.1007/s11136-008-9435-1
The Knee Arthroplasty Trial (KAT): design features, baseline characteristics, and two-year functional outcomes after alternative approaches to knee replacement
The Journal of Bone & Joint Surgery. American Volume, vol. 91, no. 1, pp. 134-141Contributions to Journals: Articles- [ONLINE] http://aura.abdn.ac.uk/handle/2164/272
- [ONLINE] DOI: https://doi.org/10.2106/JBJS.G.01074
Systematic review and economic modelling of effectiveness and cost utility of surgical treatments for men with benign prostatic enlargement
Health Technology Assessment, vol. 12, no. 35, pp. 1-168Contributions to Journals: Literature Reviews- [ONLINE] http://hdl.handle.net/2164/266
- [ONLINE] DOI: https://doi.org/10.3310/hta12350
- [OPEN ACCESS] http://aura.abdn.ac.uk/bitstream/2164/2312/1/Lourenco_2008.pdf
Minimally invasive treatments for benign prostatic enlargement: systematic review of randomised controlled trials
British Medical Journal, vol. 337, a1662Contributions to Journals: Articles- [ONLINE] http://hdl.handle.net/2164/262
- [ONLINE] DOI: https://doi.org/10.1136/bmj.a1662
- [OPEN ACCESS] http://aura.abdn.ac.uk/bitstream/2164/2313/1/Lourenco_2008.pdf
A review of RCTs in four medical journals to assess the use of imputation to overcome missing data in quality of life outcomes
Trials, vol. 9, 51Contributions to Journals: Articles- [ONLINE] DOI: https://doi.org/10.1186/1745-6215-9-51
- [OPEN ACCESS] http://aura.abdn.ac.uk/bitstream/2164/1537/1/Trials%25202008.pdf