Professor Graeme MacLennan
Health Services Research Unit
2nd Floor Health Sciences Building
I am currently Professor of Medical Statistics and the Director of the Centre for Health Care Randomised Trials (CHaRT) which is the Clinical Trials Unit embedded within the Health Services Research Unit. My overarching research interest is in designing fair tests of health care treatments and policies, with a specifc interest in evaluating surgical and complex interventions. I'm also interested in improving the design, conduct, and analysis and reporting of clinical trials through the development and application of methodological research to clinical trials from CHaRT.
My undergrad degree is in Mathematics from the University of Aberdeen, graduating in 1997. After a year training as a Mathematics teacher I joined the Unit in September 1998 as a statistician. I studied part-time for an MSc in Applied Statistics with Sheffield Hallam University, graduating in 2004. In 2008 I was appointed Senior Statistican, and in 2016 was I Interim Programme Director for the Health Care Assessment Programme, until being appointment as CHaRT Director in April 2017.
- BSc Mathematics1997 - University of Aberdeen
- MSc Applied Statistics2004 - Sheffield Hallam University
The application of statistical methods to clinical trials. Recent example is JCE paper available here on using instrumental variables in a surgery trial to address non-compliance. Collaborators were Jonathan Cook (Oxford), Tom Palmer (Lancaster), and Richard Emesley (Manchester).
Research on making trials more efficient, collaborating with Trial Forge.
A complete list of the CHaRT RCT portolio is available by clicking here
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The Achieving Self-directed Integrated Cancer Aftercare Intervention for Detection of Recurrent and Second Primary Melanoma in Survivors of Melanoma: Pilot Randomized Controlled TrialJMIR cancer, vol. 8, no. 3, e37539Contributions to Journals: Articles
Cost utility analysis of shockwave lithotripsy versus ureteroscopic stone treatment in adultsBJU InternationalContributions to Journals: Articles
Randomised controlled trial comparing the clinical and cost-effectiveness of various washout policies versus no washout policy in preventing catheter associated complications in adults living with long-term catheters: study protocol for the CATHETER II studyTrials, vol. 23, no. 1, 630Contributions to Journals: Articles
Male synthetic sling or artificial urinary sphincter (AUS) for men with urodynamic stress incontinenceafter prostate surgery: the MASTER non-inferiority randomised controlled trialHealth Technology Assessment, vol. 26, no. 36Contributions to Journals: Articles
Remotely delivered cognitive behavioural and personalised exercise interventions for fatigue severity and impact in inflammatory rheumatic diseases: a multi-centre randomised controlled parallel open-label group trial (LIFT)The Lancet Rheumatology, vol. 4, no. 8, pp. e534-e545Contributions to Journals: Articles
Cost-effectiveness of primary surgical versus primary medical management in the treatment of patients presenting with advanced glaucomaBritish Journal of OphthalmologyContributions to Journals: Articles
Effectiveness and cost-effectiveness of text messages with or without endowment incentives for weight management in men with obesity (Game of Stones): study protocol for a randomised controlled trialTrials, vol. 23, no. 1, 582Contributions to Journals: Articles
Developing a Diagnostic Multivariable Prediction Model for Urinary Tract Cancer in Patients Referred with Haematuria: results from the IDENTIFY Collaborative StudyEuropean Urology FocusContributions to Journals: Articles
Reducing asthma attacks in children using exhaled nitric oxide (RAACENO) as a biomarker to inform treatment strategy: a multicentre, parallel, randomised, controlled, phase 3 trialThe Lancet. Respiratory medicine, vol. 10, no. 6, pp. 584-592Contributions to Journals: Articles
Treatment guided by fractional exhaled nitric oxide in addition to standard care in 6- to 15-year-olds with asthma: the RAACENO RCTEfficacy and Mechanism Evaluation, vol. 9, no. 4Contributions to Journals: Articles