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  • Loss of GPR75 protects against non-alcoholic fatty liver disease and body fat accumulation

    Leeson-Payne, A., Iyinikkel, J., Malcolm, C., Lam, B. Y. H., Sommer, N., Dowsett, G. K. C., Blanco Martinez de Morentin, P., Thompson, D., MacKenzie, A., Chianese, R., Kentistou, K. A., Gardner, E. J., Perry, J. R., Grassmann, F., Speakman, J., Rochford, J., Yeo, G. S. H., Murray, F., Heisler, L.

    Cell Metabolism

    Contributions to Journals: Articles

  • Maternal dietary fat during lactation shapes single nucleus transcriptomic profile of postnatal offspring hypothalamus in a sexually dimorphic manner in mice

    Huang, Y., Wang, A., Zhou, W., Li, B., Zhang, L., Rudolf, A. M., Jin, Z., Hambly, C., Wang, G., Speakman, J. R.

    Nature Communications, vol. 15, no. 1, 2382

    Contributions to Journals: Articles

  • Behavioural variability, physical activity, rumination time, and milk characteristics of dairy cattle in response to regrouping

    Marumo, J. L., Lusseau, D., Speakman, J. R., Mackie, M., Byar, A. Y., Cartwright, W., Hambly, C.

    Animal , vol. 18, no. 3, 101094

    Contributions to Journals: Articles

  • Limits to sustained energy intake. XXXIV.: Can the heat dissipation limit (HDL) theory explain reproductive aging?

    Grosiak, M., Koteja, P., Hambly, C., Speakman, J. R., Sadowska, E. T.

    The Journal of experimental biology, vol. 227, no. 4, jeb246592

    Contributions to Journals: Articles

  • Daily energy requirements of male academy soccer players are greater than age-matched non-academy soccer players: A doubly labelled water investigation

    Stables, R. G., Hannon, M. P., Jacob, A. D., Topping, O., Costello, N. B., Boddy, L. M., Hambly, C., Speakman, J. R., Sodhi, J. S., Close, G. L., Morton, J. P.

    Journal of Sports Sciences, vol. 41, no. 12, pp. 1218-1230

    Contributions to Journals: Articles

  • Great tits (Parus major) in a west European temperate forest show little seasonal variation in metabolic energy requirements

    Pacioni, C., Sentís, M., Hambly, C., Speakman, J. R., Kerimov, A., Bushuev, A., Lens, L., Strubbe, D.

    Journal of Thermal Biology, vol. 118, pp. 103748

    Contributions to Journals: Articles

  • The effects of graded levels of calorie restriction: XX. impact of long term graded calorie restriction on survival and body mass dynamics in male C57BL/6J mice

    Mitchell, S. E., Togo, J., Green, C. L., Derous, D., Hambly, C., Speakman, J. R.

    The Journals of Gerontology. Series A, Biological Sciences and Medical Sciences, vol. 78, no. 11, pp. 1953-1963

    Contributions to Journals: Articles

  • Validation of the 2 × 24 h recall method and a 7-d web-based food diary against doubly labelled water in Danish adults

    Biltoft-Jensen, A., Ygil, K. H., Knudsen, L., Matthiessen, J., Fagt, S., Trolle, E., Nielsen, T. H., Hansen, D. M., Licht, C. L., Martens, M., Hambly, C., Speakman, J. R., Christensen, T.

    British Journal of Nutrition, vol. 130, no. 8, pp. 1444-1457

    Contributions to Journals: Articles

  • Models of body weight and fatness regulation

    Speakman, J. R., Hall, K. D.

    Philosophical Transactions of the Royal Society B: Biological Sciences, vol. 378, no. 1888, 20220231

    Contributions to Journals: Review articles

  • Greater male variability in daily energy expenditure develops through puberty

    Halsey, L. G., Careau, V., Ainslie, P. N., Alemán-Mateo, H., Andersen, L. F., Anderson, L. J., Arab, L., Baddou, I., Bandini, L., Bedu-Addo, K., Blaak, E. E., Blanc, S., Bonomi, A. G., Bouten, C. V. C., Bovet, P., Brage, S., Buchowski, M. S., Butte, N., Camps, S. G., Casper, R., Close, G. L., Colbert, L. H., Cooper, J. A., Cooper, R., Dabare, P., Das, S. K., Davies, P. S. W., Deb, S., Nyström, C. D., Dietz, W., Dugas, L. R., Eaton, S., Ekelund, U., Hamdouchi, A. E., Entringer, S., Forrester, T., Fudge, B. W., Gillingham, M., Goris, A. H., Gurven, M., Haisma, H., Hambly, C., Hoffman, D., Hoos, M. B., Hu, S., Joonas, N., Joosen, A., Katzmarzyk, P., Kempen, K. P., Wood, B., IAEA DLW Database Consortium

    Biology Letters, vol. 19, no. 9, 20230152

    Contributions to Journals: Articles

  • A step toward precision gerontology: Lifespan effects of calorie and protein restriction are consistent with predicted impacts on entropy generation

    Semerciöz-Oduncuoğlu, A. S., Mitchell, S. E., Özilgen, M., Yilmaz, B., Speakman, J. R.

    Proceedings of the National Academy of Sciences of the United States of America, vol. 120, no. 37, e2300624120

    Contributions to Journals: Articles

  • Quantifying physical activity energy expenditure based on doubly labelled water and basal metabolism calorimetry: what are we actually measuring?

    Speakman, J. R., Pontzer, H.

    Current Opinion in Clinical Nutrition and Metabolic Care, vol. 26, no. 5, pp. 401-408

    Contributions to Journals: Review articles

  • Unanswered questions about the causes of obesity: Obesity is now a global pandemic, but there is little consensus about the causes.

    Speakman, J. R., Sørensen, T. I., Hall, K. D., Allison, D. B.

    Science (New York, N.Y.), vol. 381, no. 6661, pp. 944-946

    Contributions to Journals: Articles

  • The bioelectrical impedance analysis (BIA) international database: aims, scope, and call for data

    Silva, A. M., Campa, F., Stagi, S., Gobbo, L. A., Buffa, R., Toselli, S., Silva, D. A. S., Gonçalves, E. M., Langer, R. D., Guerra-Júnior, G., Machado, D. R. L., Kondo, E., Sagayama, H., Omi, N., Yamada, Y., Yoshida, T., Fukuda, W., Gonzalez, M. C., Orlandi, S. P., Koury, J. C., Moro, T., Paoli, A., Kruger, S., Schutte, A. E., Andreolli, A., Earthman, C. P., Fuchs-Tarlovsky, V., Irurtia, A., Castizo-Olier, J., Mascherini, G., Petri, C., Busert, L. K., Cortina-Borja, M., Bailey, J., Tausanovitch, Z., Lelijveld, N., Ghazzawi, H. A., Amawi, A. T., Tinsley, G., Kangas, S. T., Salpéteur, C., Vázquez-Vázquez, A., Fewtrell, M., Ceolin, C., Sergi, G., Ward, L. C., Heitmann, B. L., da Costa, R. F., Vicente-Rodriguez, G., Cremasco, M. M., Moroni, A., Shepherd, J., Moon, J., Knaan, T., Müller, M. J., Braun, W., García-Almeida, J. M., Palmeira, A. L., Santos, I., Larsen, S. C., Zhang, X., Speakman, J. R., Plank, L. D., Swinburn, B. A., Ssensamba, J. T., Shiose, K., Cyrino, E. S., Bosy-Westphal, A., Heymsfield, S. B., Lukaski, H., Sardinha, L. B., Wells, J. C., Marini, E.

    European Journal of Clinical Nutrition

    Contributions to Journals: Articles

  • GDF15 promotes weight loss by enhancing energy expenditure in muscle

    Wang, D., Townsend, L. K., DesOrmeaux, G. J., Frangos, S. M., Batchuluun, B., Dumont, L., Kuhre, R. E., Ahmadi, E., Hu, S., Rebalka, I. A., Gautam, J., Jabile, M. J. T., Pileggi, C. A., Rehal, S., Desjardins, E. M., Tsakiridis, E. E., Lally, J. S., Juracic, E. S., Tupling, A. R., Gerstein, H. C., Paré, G., Tsakiridis, T., Harper, M. E., Hawke, T. J., Speakman, J. R., Blondin, D. P., Holloway, G. P., Jørgensen, S. B., Steinberg, G. R.

    Nature, vol. 619, no. 7968, pp. 143-150

    Contributions to Journals: Articles

  • Disentangling the effects of obesity and high-fat diet on glucose homeostasis using a photoperiod induced obesity model implicates ectopic fat deposition as a key factor

    Yang, D. B., Gao, L., Liu, X. Y., Xu, Y. C., Hambly, C., Wang, D. H., Speakman, J. R.

    Molecular Metabolism, vol. 73, 101724

    Contributions to Journals: Articles

  • The effects of graded levels of calorie restriction: XIX. Impact of graded calorie restriction on protein expression in the liver

    Wang, L., Derous, D., Huang, X., Mitchell, S. E., Douglas, A., Lusseau, D., Wang, Y., Speakman, J. R.

    The Journals of Gerontology. Series A, Biological Sciences and Medical Sciences, vol. 78, no. 7, pp. 1125-1134

    Contributions to Journals: Articles

  • An Observational Case Series Measuring the Energy Expenditure of Elite Tennis Players During Competition and Training by Using Doubly Labeled Water

    Ellis, D. G., Speakman, J., Hambly, C., Morton, J. P., Close, G. L., Donovan, T. F.

    International journal of sports physiology and performance, vol. 18, no. 5, pp. 547-552

    Contributions to Journals: Articles

  • Total daily energy expenditure has declined over the past three decades due to declining basal expenditure, not reduced activity expenditure

    Speakman, J. R., de Jong, J. M. A., Sinha, S., Westerterp, K. R., Yamada, Y., Sagayama, H., Ainslie, P. N., Anderson, L. J., Arab, L., Bedu-Addo, K., Blanc, S., Bonomi, A. G., Bovet, P., Brage, S., Buchowski, M. S., Butte, N. F., Camps, S. G. J. A., Cooper, J. A., Cooper, R., Das, S. K., Davies, P. S. W., Dugas, L. R., Ekelund, U., Entringer, S., Forrester, T., Fudge, B. W., Gillingham, M., Ghosh, S., Goris, A. H., Gurven, M., Halsey, L. G., Hambly, C., Haisma, H. H., Hoffman, D., Hu, S., Joosen, A. M., Kaplan, J. L., Katzmarzyk, P., Kraus, W. E., Kushner, R. F., Leonard, W. R., Löf, M., Martin, C. K., Matsiko, E., Medin, A. C., Meijer, E. P., Neuhouser, M. L., Nicklas, T. A., Ojiambo, R. M., Pietiläinen, K. H., Plange-Rhule, J., Plasqui, G., Prentice, R. L., Racette, S. B., Raichlen, D. A., Ravussin, E., Redman, L. M., Roberts, S. B., Rudolph, M. C., Sardinha, L. B., Schuit, A. J., Silva, A. M., Stice, E., Urlacher, S. S., Valenti, G., Van Etten, L. M., Van Mil, E. A., Wood, B. M., Yanovski, J. A., Yoshida, T., Zhang, X., Murphy-Alford, A. J., Loechl, C. U., Kurpad, A., Luke, A. H., Pontzer, H., Rodeheffer, M. S., Rood, J., Schoeller, D. A., Wong, W. W.

    Nature Metabolism, vol. 5, no. 4, pp. 579-588

    Contributions to Journals: Articles

  • Case-study: Energy expenditure of a world class male wheelchair tennis player during training, Grand Slam and British open tournaments measured by doubly labelled water

    Ellis, D. G., Speakman, J., Hambly, C., Cockram, A., Morton, J. P., Close, G. L., Donovan, T. F.

    International Journal of Sports Science and Coaching

    Contributions to Journals: Articles

  • Fur removal promotes an earlier expression of involution-related genes in mammary gland of lactating mice

    Krol, E., Turner, F., Derous, D., Mitchell, S. E., Martin, S., Douglas, A., Speakman, J.

    Journal of Comparative Physiology. B, Biochemical, Systemic, and Environmental Physiology, pp. 171-192

    Contributions to Journals: Articles

  • High dietary protein and fat contents exacerbate hepatic senescence and SASP in mice

    Nehme, J., Yang, D., Altulea, A., Varela-Eirin, M., Wang, L., Hu, S., Wu, Y., Togo, J., Niu, C., Speakman, J. R., Demaria, M.

    FEBS Journal, vol. 290, no. 5, pp. 1340-1347

    Contributions to Journals: Articles

  • Large scale phenotype imputation and in vivo functional validation implicate ADAMTS14 as an adiposity gene

    Kentistou, K. A., Luan, J., Wittemans, L. B. L., Hambly, C., Klaric, L., Kutalik, Z., Speakman, J. R., Wareham, N. J., Kendall, T. J., Langenberg, C., Wilson, J. F., Joshi, P. K., Morton, N. M.

    Nature Communications, vol. 14, 307

    Contributions to Journals: Articles

  • The energy balance model of obesity: beyond calories in, calories out

    Hall, K. D., Farooqi, I. S., Friedman, J. M., Klein, S., Loos, R. J., Mangelsdorf, D. J., O'Rahilly, S., Ravussin, E., Redman, L. M., Ryan, D. H., Speakman, J. R., Tobias, D. K.

    American Journal of Clinical Nutrition, vol. 115, no. 5, pp. 1243-1254

    Contributions to Journals: Articles

  • Variation in human water turnover associated with environmental and lifestyle factors

    Yamada, Y., Zhang, X., Henderson, M. E. T., Sagayama, H., Pontzer, H., Watanabe, D., Yoshida, T., Kimura, M., Ainslie, P. N., Andersen, L. F., Anderson, L. J., Arab, L., Baddou, I., Bedu-Addo, K., Blaak, E. E., Blanc, S., Bonomi, A. G., Bouten, C. V. C., Bovet, P., Buchowski, M. S., Butte, N. F., Camps, S. G., Close, G. L., Cooper, J. A., Cooper, R., Das, S. K., Dugas, L. R., Eaton, S., Ekelund, U., Entringer, S., Forrester, T., Fudge, B. W., Goris, A. H., Gurven, M., Halsey, L. G., Hambly, C., El Hamdouchi, A., Hoos, M. B., Hu, S., Joonas, N., Joosen, A. M., Katzmarzyk, P., Kempen, K. P., Kraus, W. E., Kriengsinyos, W., Kushner, R. F., Lambert, E. V., Leonard, W. R., Lessan, N., Speakman, J. R., International Atomic Energy Agency (IAEA) Doubly Labeled Water (DLW) Database Consortium

    Science, vol. 378, no. 6622, pp. 909-915

    Contributions to Journals: Articles

  • Focus on diet and exercise

    Speakman, J., Johnstone, A., Moholdt, T., Panda, S., Klein, S., Parker, B. L., Goodyear, L.

    Contributions to Journals

  • Higher than predicted resting energy expenditure and lower physical activity in healthy underweight Chinese adults

    Hu, S., Zhang, X., Stamatiou, M., Hambly, C., Huang, Y., Ma, J., Li, Y., Speakman, J. R.

    Cell Metabolism, vol. 34, no. 10, pp. 1413-1415

    Contributions to Journals: Letters

  • Variability in energy expenditure is much greater in males than females

    Halsey, L. G., Careau, V., Pontzer, H., Ainslie, P. N., Andersen, L. F., Anderson, L. J., Arab, L., Baddou, I., Bedu-Addo, K., Blaak, E. E., Blanc, S., Bonomi, A. G., Bouten, C. V. C., Bovet, P., Buchowski, M. S., Butte, N. F., Camps, S. G. J. A., Close, G. L., Cooper, J. A., Das, S. K., Cooper, R., Dugas, L. R., Ekelund, U., Entringer, S., Forrester, T., Fudge, B. W., Goris, A. H., Gurven, M., Hambly, C., Hamdouchi, A. E., Hoos, M. B., Hu, S., Joonas, N., Joosen, A. M., Katzmarzyk, P., Kempen, K. P., Kimura, M., Kraus, W. E., Kushner, R. F., Lambert, E. V., Leonard, W. R., Lessan, N., Martin, C. K., Medin, A. C., Meijer, E. P., Morehen, J. C., Morton, J. P., Neuhouser, M. L., Nicklas, T. A., Ojiambo, R. M., Pietiläinen, K. H., Pitsiladis, Y. P., Plange-Rhule, J., Plasqui, G., Prentice, R. L., Rabinovich, R. A., Racette, S. B., Raichlen, D. A., Ravussin, E., Reynolds, R. M., Roberts, S. B., Schuit, A. J., Sjödin, A. M., Stice, E., Urlacher, S. S., Valenti, G., Van Etten, L. M., Van Mil, E. A., Wilson, G., Wood, B. M., Yanovski, J., Yoshida, T., Zhang, X., Murphy-Alford, A. J., Loechl, C. U., Luke, A. H., Rood, J., Sagayama, H., Schoeller, D. A., Westerterp, K. R., Wong, W. W., Yamada, Y., Speakman, J. R.

    Journal of Human Evolution, vol. 171, 103229

    Contributions to Journals: Articles

  • The effects of graded levels of calorie restriction XVIII: tissue specific changes in cell size and number in response to calorie restriction

    Phillips, D., Mathers, H., Mitchell, S. E., Speakman, J. R.

    The Journals of Gerontology. Series A, Biological Sciences and Medical Sciences, vol. 77, no. 10, pp. 1994-2001

    Contributions to Journals: Articles

  • Human total, basal and activity energy expenditures are independent of ambient environmental temperature

    Zhang, X., Yamada, Y., Sagayama, H., Ainslie, P. N., Blaak, E. E., Buchowski, M. S., Close, G. L., Cooper, J. A., Das, S. K., Dugas, L. R., Gurven, M., El Hamdouchi, A., Hu, S., Joonas, N., Katzmarzyk, P., Kraus, W. E., Kushner, R. F., Leonard, W. R., Martin, C. K., Meijer, E. P., Neuhouser, M. L., Ojiambo, R. M., Pitsiladis, Y. P., Plasqui, G., Prentice, R. L., Racette, S. B., Ravussin, E., Redman, L. M., Reynolds, R. M., Roberts, S. B., Sardinha, L. B., Silva, A. M., Stice, E., Urlacher, S. S., Van Mil, E. A., Wood, B. M., Murphy-Alford, A. J., Loechl, C., Luke, A. H., Rood, J., Schoeller, D. A., Westerterp, K. R., Wong, W. W., Pontzer, H., Speakman, J. R., IAEA DLW Database Consortium

    iScience, vol. 25, no. 8, 104682

    Contributions to Journals: Articles

  • Reply to G Taubes, MI Friedman, and V Torres-Carot et al.

    Hall, K. D., Farooqi, I. S., Friedman, J. M., Klein, S., Loos, R. J., Mangelsdorf, D. J., O’Rahilly, S., Ravussin, E., Redman, L. M., Ryan, D. H., Speakman, J. R., Tobias, D. K.

    American Journal of Clinical Nutrition, vol. 116, no. 2, pp. 614-615

    Contributions to Journals: Letters

  • Accelerating animal energetics: high dive costs in a small seabird disrupt the dynamic body acceleration-energy expenditure relationship

    Ste-Marie, E., Grémillet, D., Fort, J., Patterson, A., Brisson-Curadeau, ., Clairbaux, M., Perret, S., Speakman, J. R., Elliott, K. H.

    Journal of Experimental Biology, vol. 225, no. 12, jeb243252

    Contributions to Journals: Articles

  • Inhibitors of dihydroorotate dehydrogenase cooperate with molnupiravir and N4-hydroxycytidine to suppress SARS-CoV-2 replication

    Stegmann, K. M., Dickmanns, A., Heinen, N., Blaurock, C., Karrasch, T., Breithaupt, A., Klopfleisch, R., Uhlig, N., Eberlein, V., Issmail, L., Herrmann, S. T., Schreieck, A., Peelen, E., Kohlhof, H., Sadeghi, B., Riek, A., Speakman, J. R., Groß, U., Görlich, D., Vitt, D., Müller, T., Grunwald, T., Pfaender, S., Balkema-Buschmann, A., Dobbelstein, M.

    iScience, vol. 25, no. 5, 104293

    Contributions to Journals: Articles

  • Energy Expenditure of Female International Standard Soccer Players: A Doubly Labeled Water Investigation

    Morehen, J. C., Rosimus, C., Cavanagh, B. P., Hambly, C., Speakman, J. R., Elliott-Sale, K. J., Hannon, M. P., Morton, J. P.

    Medicine and Science in Sports and Exercise, vol. 54, no. 5, pp. 769-779

    Contributions to Journals: Articles

  • Higher metabolic plasticity in temperate compared to tropical lizards suggests increased resilience to climate change

    Sun, B., Williams, C. M., Li, T., Speakman, J. R., Jin, Z., Lu, H., Luo, L., Du, W.

    Ecological Monographs, vol. 92, no. 2, e1512

    Contributions to Journals: Articles

  • Effects of dietary macronutrients on the hepatic transcriptome and serum metabolome in mice

    Wu, Y., Green, C. L., Wang, G., Yang, D., Li, L., Li, B., Wang, L., Li, M., Li, J., Xu, Y., Zhang, X., Niu, C., Hu, S., Togo, J., Mazidi, M., Derous, D., Douglas, A., Speakman, J.

    Aging Cell, vol. 21, no. 4, e13585

    Contributions to Journals: Articles

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