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The Institute of Medical Sciences

Professor David Lurie

Professor David Lurie
Professor David Lurie
Professor David Lurie

PhD, DUniv (honoris causa), FInstP, FIPEM, FISMRM

Emeritus Professor

About
Email Address
d.lurie@abdn.ac.uk
School/Department
School of Medicine, Medical Sciences and Nutrition
ORCiD

Biography

Since my retirement in October 2021, I have been an Emeritus Professor at the University of Aberdeen. I previously held a Chair in Biomedical Physics at the University (2002-21), where I researched and taught MRI Physics, starting when I joined Jim Hutchison’s team in 1983.

My research was concerned with the development of MRI technology and its bio-medical applications, most recently in the area of Fast Field-Cycling MRI, which was pioneered by the group that I led. Whereas standard MRI scanners operate at a single magnetic field (e.g. 1.5 T or 3 T), FFC scanners have the ability to switch magnetic field rapidly during a scan, thereby obtaining information on the variation of the NMR relaxation times with magnetic field strength. Results indicate that this can provide a valuable new contrast mechanism for clinical MRI.

During my career I obtained research grants totalling over £11.1m as Principal Investigator. In 2015 a consortium of seven research laboratories and two companies, coordinated by me, secured €6.60m (£5.92m) from the European Union’s Horizon 2020 scheme to develop FFC-MRI as a clinical imaging modality; the “IDentIFY” project ran for 4 years from January 2016.

I have given over 100 invited, keynote and plenary lectures at conferences and workshops world-wide. I am author of 90 peer-reviewed papers, 8 book chapters as well as 290 conference abstracts.

My CV can be found here and my bibliography is available here.

Qualifications

  • BSc (Hons) Natural Philosophy 
    1979 - University of Aberdeen 
  • MSc Radiation Physics 
    1980 - University of London 
  • PhD Medical Physics 
    1984 - University of London 

External Memberships

I am Past Chair of the Communications and Publications Committee of the European Federation of Organisations for Medical Physics (EFOMP), having been Chair from January 2020 to February 2022.

Prizes and Awards

In 2017 I was awarded the Academic Gold Medal of the Institute of Physics and Engineering in Medicine (IPEM).
In 2021 I was awarded Senior Fellowship of the International Society for Magnetic Resonance in Medicine (ISMRM).
In 2022 I was given an Honorary Doctorate (D.Univ., honoris causa) by the University of the Highlands and Islands.

Publications

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  • Detection of osteoarthritis in knee and hip joints by fast field-cycling NMR

    Broche, L. M., Ashcroft, G. P., Lurie, D. J.
    Magnetic Resonance in Medicine, vol. 68, no. 2, pp. 358-362
    Contributions to Journals: Articles

  • Human relaxometry and MRI using fast field-cycling

    Lurie, D. J., Broche, L., Davies, G. R., Pine, K. J., Ross, P. J.
    AMPERE NMR School (2012), pp. 22
    Contributions to Conferences: Abstracts

  • Measurement of fibrin concentration by fast field-cycling NMR

    Broche, L. M., Ismail, S. R., Booth, N. A., Lurie, D. J.
    Magnetic Resonance in Medicine, vol. 67, no. 5, pp. 1453–1457
    Contributions to Journals: Articles

  • QUANTITATIVE AND NON-INVASIVE DETECTION OF PROTEOGLYCAN BY FAST FIELD-CYCLING NUCLEAR MAGNETIC RESONANCE

    Broche, L. M., Ashcroft, G. P., Lurie, D. J.
    World Congress on Osteoarthritis, pp. S92-S93
    Contributions to Journals: Abstracts

  • Absorption Methods for ESR and NMR Imaging of Solid Materials

    Fagan, A. J., Lurie, D. J.
    MRI of Tissues with Short T2s or T2*s. Bydder, G., Young, I. (eds.). John Wiley & Sons Ltd., pp. 171-184, 14 pages
    Chapters in Books, Reports and Conference Proceedings: Chapters

  • The use of contrast agents with fast field-cycling magnetic resonance imaging

    O Hogain, D., Davies, G. R., Baroni, S., Aime, S., Lurie, D. J.
    Physics in Medicine and Biology, vol. 56, no. 1, pp. 105-115
    Contributions to Journals: Articles

  • Design and construction of an actively frequency-switchable RF coil for field-dependent Magnetisation Transfer Contrast MRI with fast field-cycling

    Choi, C., Hutchison, J. M. S., Lurie, D. J.
    Journal of Magnetic Resonance, vol. 207, no. 1, pp. 134-139
    Contributions to Journals: Articles

  • A novel variable field system for field-cycled dynamic nuclear polarization spectroscopy

    Shet, K., Caia, G. L., Kesselring, E., Samouilov, A., Petryakov, S., Lurie, D. J., Zweier, J. L.
    Journal of Magnetic Resonance, vol. 205, no. 2, pp. 202-208
    Contributions to Journals: Articles

  • Field-cycling NMR relaxometry with spatial selection

    Pine, K. J., Davies, G. R., Lurie, D. J.
    Magnetic Resonance in Medicine, vol. 63, no. 6, pp. 1698-1702
    Contributions to Journals: Articles

  • Off-resonance magnetisation transfer contrast (MTC) MRI using fast field-cycling (FFC)

    Choi, C., Davies, G. R., Lurie, D. J.
    Journal of Magnetic Resonance, vol. 204, no. 1, pp. 145-149
    Contributions to Journals: Articles

  • Fast field-cycling magnetic resonance imaging: Imagerie de resonance magnétique en champ cyclé

    Lurie, D. J., Aime, S., Baroni, S., Booth, N. A., Broche, L. M., Choi, C., Davies, G. R., Ismail, S., O Hogain, D., Pine, K. J.
    Comptes Rendus. Physique, vol. 11, no. 2, pp. 136-148
    Contributions to Journals: Articles

  • Field-cycled dynamic nuclear polarization (FC-DNP) of 14N and 15N nitroxide free radicals at low magnetic field

    Polyon, C., Lurie, D. J., Youngdee, W., Thomas, C., Thomas, I.
    Journal of Physics D: Applied Physics, vol. 40, no. 18, pp. 5527-5532
    Contributions to Journals: Articles

  • Real-time monitoring of drug-induced changes in the stomach acidity of living rats using improved pH-sensitive nitroxides and low-field EPR techniques

    Potapenko, D. I., Foster, M. A., Lurie, D. J., Kirilyuk, I. A., Hutchison, J. M. S., Grigor'ev, I. A., Bagryanskaya, E. G., Khramtsov, V. V.
    Journal of Magnetic Resonance, vol. 182, pp. 1-11
    Contributions to Journals: Articles

  • Sequential, Co-registered Fluorine and Proton Field-Cycled Overhauser Imaging at a Detection Field of 59 mT

    Modica, A., Alecci, A., Lurie, D. J.
    Physics in Medicine and Biology, vol. 51, pp. N39-N45
    Contributions to Journals: Articles

  • The excretion mechanism of the spin label proxyl carboxylic acid (PCA) from the rat monitored by X-band ESR and PEDRI

    Seimenis, I., Foster, M. A., Lurie, D. J., Hutchison, J. M., Whiting, P. H., Payne, S.
    Magnetic Resonance in Medicine, vol. 37, no. 4, pp. 552-558
    Contributions to Journals: Articles

  • Development of a 3-D, multi-nuclear continuous wave NMR imaging system

    Fagan, A. J., Davies, G. R., Hutchison, J. M. S., Glasser, F. P., Lurie, D. J.
    Journal of Magnetic Resonance, vol. 176, no. 2, pp. 140-150
    Contributions to Journals: Articles

  • Field-cycled PEDRI imaging of free radicals with detection at 450 mT

    Lurie, D. J., Davies, G. R., Foster, M. A., Hutchison, J. M. S.
    Magnetic Resonance Imaging, vol. 23, no. 2, pp. 175-181
    Contributions to Journals: Articles

  • Proton electron double resonance imaging of free radical distribution in environmental science applications: first results and perspectives

    Nestle, N., Shet, K., Lurie, D. J.
    Magnetic Resonance Imaging, vol. 23, no. 2, pp. 183-189
    Contributions to Journals: Articles

  • Continuous Wave NMR Imaging in the Solid State

    Fagan, A. J., Lurie, D. J.
    Annual Reports on NMR Spectroscopy, vol. 56, pp. 97-140
    Contributions to Journals: Articles

  • Continuous wave MRI diffusion study of water in bentonite clay

    Fagan, A. J., Nestle, N., Lurie, D. J.
    Magnetic Resonance Imaging, vol. 23, pp. 317-319
    Contributions to Journals: Articles

  • Monitoring drug delivery processes by EPR and related techniques – principles and applications

    Lurie, D. J., Maeder, K.
    Advanced Drug Delivery Reviews, vol. 57, pp. 1171-1190
    Contributions to Journals: Articles

  • In Vitro and In Vivo Measurement of pH and Thiols by EPR-Based Techniques

    Khramtsov, V. V., Grigor'ev, I. A., Foster, M. A., Lurie, D. J.
    Antioxidants & Redox Signaling, vol. 6, pp. 667-676
    Contributions to Journals: Articles

  • Spin pH and SH probes: enhancing functionality of EPR-based techniques

    Khramtsov, V. V., Grigor'ev, I. A., Lurie, D. J., Foster, M. A., Zweier, J. L., Kuppusamy, P.
    Spectroscopy, vol. 18, pp. 213-225
    Contributions to Journals: Articles

  • Continuous wave MRI of heterogeneous materials

    Fagan, A. J., Davies, G. R., Hutchison, J. M. S., Lurie, D. J.
    Journal of Magnetic Resonance, vol. 163, no. 2, pp. 318-324
    Contributions to Journals: Articles

  • In vivo detection of a pH-sensitive nitroxide in the rat stomach by low-field ESR-based techniques

    Foster, M. A., Grigor'ev, I. A., Khramtsov, V. V., McCallum, S. J., Hutchison, J. M. S., Koptioug, A., Nicholson, I., Lurie, D. J., Panagiotelis, I.
    Magnetic Resonance in Medicine, vol. 49, no. 3, pp. 558-567
    Contributions to Journals: Articles

  • Proton Electron Double Resonance Imaging (PEDRI)

    Lurie, D. J.
    In Vivo EPR (ESR): Theory and Applications. Biological Magnetic Resonance, Vol. 18, ed: L.J. Berliner, pp. 547-548, 1 page
    Chapters in Books, Reports and Conference Proceedings: Chapters

  • Development of a PEDRI free-radical imager using a 0.38 T clinical MRI system

    Lurie, D. J., Li, H., Petryakov, S., Zweier, J. L.
    Magnetic Resonance in Medicine, vol. 47, no. 1, pp. 181-186
    Contributions to Journals: Articles

  • Proton electron double resonance imaging of the in vivo distribution and clearance of a triaryl methyl radical in mice

    Li, H., Deng, Y., Kuppusamy, P., Lurie, D. J., Zweier, J. L.
    Magnetic Resonance in Medicine, vol. 48, pp. 530-534
    Contributions to Journals: Articles

  • Rapid imaging of free radicals in vivo using hybrid FISP field-cycled PEDRI

    Youngdee, W., Lurie, D. J., Foster, M. A.
    Physics in Medicine and Biology, vol. 47, no. 7, pp. 1091-1100
    Contributions to Journals: Articles

  • Recent Progress and Future Prospects of Free Radical Imaging by PEDRI

    Lurie, D. J., Foster, M. A., Youngdee, W., Khramtsov, V. V., Grigor'ev, I. A.
    EPR in the 21st Century, pp. 515-523, 8 pages
    Chapters in Books, Reports and Conference Proceedings: Chapters

  • Techniques and Applications of EPR Imaging

    Lurie, D. J.
    Electron Paramagnetic Resonance; Specialist Periodical Reports, Royal Society of Chemistry, pp. 137-160, 23 pages
    Chapters in Books, Reports and Conference Proceedings: Chapters

  • Continuous-Wave MRI of Short T2 Materials

    Davies, G. R., Lurie, D. J., Hutchison, J. M. S., McCallum, S. J., Nicholson, I.
    Journal of Magnetic Resonance, vol. 148, pp. 289-297
    Contributions to Journals: Articles

  • Free radical imaging

    Lurie, D. J.
    British Journal of Radiology, vol. 74, no. 885, pp. 782-784
    Contributions to Journals: Articles

  • Optimization of field-cycled PEDRI for in vivo imaging of free radicals

    Youngdee, W., Planinsic, G., Lurie, D. J.
    Physics in Medicine and Biology, vol. 46, no. 10, pp. 2531-2544
    Contributions to Journals: Articles

  • Biological applications of spin pH probes

    Khramtsov, V. V., Grigor'ev, I. A., Foster, M. A., Lurie, D. J., Nicholson, I.
    Cellular and Molecular Biology, vol. 46, pp. 1361-1374
    Contributions to Journals: Articles

  • Overhauser Effect Imaging of Free Radicals

    Lurie, D. J.
    Methods in Biomedical Magnetic Resonance Imaging and Spectroscopy. Young, I., Grant, D. (eds.)
    Chapters in Books, Reports and Conference Proceedings: Chapters

  • Detection of nitrosyl-iron complexes by proton-electron-double-resonance imaging

    Mulsch, A., Lurie, D. J., Seimenis, I., Fichtlscherer, B., Foster, M. A.
    Free Radical Biology and Medicine, vol. 27, pp. 636-646
    Contributions to Journals: Articles

  • Low field (10 mT) pulsed dynamic nuclear polarization

    Alecci, M., Lurie, D. J.
    Journal of Magnetic Resonance, vol. 138, pp. 313-319
    Contributions to Journals: Articles

  • Rapid imaging of free radicals in vivo using field cycled PEDRI

    Puwanich, P., Lurie, D. J., Foster, M. A.
    Physics in Medicine and Biology, vol. 44, pp. 2867-2877
    Contributions to Journals: Articles

  • Chemically induced analgesic nephropathy in the rat monitored by proton‐electron double‐resonance imaging (PEDRI)

    Seimenis, I., Foster, M., Lurie, D., Hutchison, J., Whiting, P., Payne, S.
    Magnetic Resonance in Medicine, vol. 40, no. 2, pp. 280-286
    Contributions to Journals: Articles

  • Design, construction and use of a large-sample field-cycled PEDRI imager

    Lurie, D. J., Foster, M. A., Yeung, D., Hutchison, J. M. S.
    Physics in Medicine and Biology, vol. 43, no. 7, pp. 1877-1886
    Contributions to Journals: Articles

  • Nitroxide free radical clearance in the live rat monitored by radio- frequency CW-EPR and PEDRI

    Alecci, M., Seimenis, I., McCallum, S. J., Lurie, D. J., Foster, M. A.
    Physics in Medicine and Biology, vol. 43, no. 7, pp. 1899-1905
    Contributions to Journals: Articles

  • Recent developments in combining LODESR imaging with proton NMR imaging

    Nicholson, I., Robb, F. J., McCallum, S. J., Koptioug, A., Lurie, D. J.
    Physics in Medicine and Biology, vol. 43, no. 7, pp. 1851-1855
    Contributions to Journals: Articles

  • The application of PEDRI to the study of free radicals in vivo

    Foster, M. A., Seimenis, I., Lurie, D. J.
    Physics in Medicine and Biology, vol. 43, no. 7, pp. 1893-1897
    Contributions to Journals: Articles

  • A Submicrosecond Resonator and Receiver System for Pulsed Magnetic Resonance with Large Samples

    Alecci, M., Brivati, J. A., Placidi, G., Testa, L., Lurie, D. J., Sotgiu, A.
    Journal of Magnetic Resonance, vol. 132, no. 1, pp. 162-166
    Contributions to Journals: Articles

  • Multimodality magnetic resonance systems for studying free radicals in vivo

    McCallum, S. J., Nicholson, I., Lurie, D. J.
    Physics in Medicine and Biology, vol. 43, no. 7, pp. 1857-1861
    Contributions to Journals: Articles

  • Magnetic resonance imaging of nitric oxide

    Fichtlscherer, B., Seimenis, I., Lurie, D., Foster, M., Mulsch, A.
    Naunyn-Schmiedeberg's Archives of Pharmacology, vol. 355, no. 4, pp. 146-146
    Contributions to Journals: Abstracts

  • In vivo imaging of nitroxide-free-radical clearance in the rat, using radiofrequency longitudinally detected ESR imaging

    Nicholson, I., Foster, M. A., Robb, F. J., Hutchison, J. M., Lurie, D. J.
    Journal of Magnetic Resonance - Series B, vol. 113, no. 3, pp. 256-261
    Contributions to Journals: Articles

  • Commentary: Electron spin resonance imaging studies of biological systems

    Lurie, D. J.
    Contributions to Journals: Short Survey

  • A combined PEDRI and CW-EPR instrument for detecting free radicals in vivo

    McCallum, S. J., Nicholson, I., Lurie, D. J.
    Journal of Magnetic Resonance - Series B, vol. 113, no. 1, pp. 65-69
    Contributions to Journals: Articles
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