Katie's research interests focus on the design and delivery of participant centred trials: from point of in initial contact through to feeding back results to individuals. This work is multi-disciplinary and multi-stakholder and involves using mixed methods approaches to develop, evaluate and implement interventions to support decision making in this context. Other aspects of her research are interested in developing measures to assess how potential participants make decisions about trial participation (including the development of a methodological core outcome set) and exploring what types of information people find useful for decision making. Much of Katie’s work brings together the fields of trials methodology with shared-decision making, with a focus on bringing together these disciplines to improve decision making and research experience for potential trial participants. Katie has initiated work relating to development and implementation of core outcome sets for methodological research problems, where originally these core outcome sets have been applied only in clinical contexts.
Other aspects of Katie's work are interested in the application of behavioural science to trials methodology. For example, framing problems of recruitment and retention as behaviours and exploring the opportunities to improve these aspects through the design of participant centred, theoretically informed, interventions.
Katie is also interested, more broadly, in embedding mixed-methods process evaluations and patient involvement in trials to improve both the experience for potential participants and the overall efficiency of the trial. Work in this area is ongoing across the portfolio of CHaRT trials.
Links to Katie's recent projects can be seen below;
Research Funding and Grants
1. Saraswat L, Gillies K, Maclennan G, Scotland G, Cooper K, Bhattacharya S, Cox E, Jones G. REGAL: Recurrence of endometriosis: GnRH anlogues versus Laparoscopic surgery. NIHR HTA Programme. 08/19. £1,660, 142
2. Treweek S, Gillies K, Gardner H, Pickles D, El Feky A, Dawson A. A Good Use Of Time And Money? Providing Evidence For How Effort Is Invested In Primary And Secondary Outcome Data Collection In Trials. Chief Scientist Office of the Scottish Government’s Health & Social Care Directorate. 03/19-02/21. £224,213
3. Gillies K (CI), Locock L, Ahmed I. Narratives to support decisions about trial participation: investigation of purpose and content in reference to decision making. NHS Grampian. 04/18 – 04/19. £11,851
4. Maheshwari A, Cooper K, Saraswat L, Bhattacharya S, Breeman S, Gillies K, Horne A, Daniels J, Brian K , Burns G. Surgery for women with endometrioma prior to IVF- Assessing the feasibility of a multicentre randomised trial in UK. NHS Grampian 05/18-05/19. £24,995
5. Gillies K (CI), Brueton V, Devane D, Gamble C, Treweek S. Setting Research Priorities for Improving Participant Retention in Clinical Trials: A Consensus Based Multi-Stakeholder Approach. Chief Scientist Office of the Scottish Government’s Health & Social Care Directorate. 06/18 £23,550.
6. Jayasena C, Hernandez R, Gillies K, Brazelli M, Bhattacharya S. Effects and Safety of Testosterone in Men with Low Testosterone levels: an evidence synthesis and economic evaluation. The TESTES (Testosterone Effects and Safety) Consortium. 08/18-08/20. £508,667.80
7. Treweek S, Gillies K, Gardner H, Pickles D, El Feky A, Dawson A. A Good Use Of Time And Money? Providing Evidence For How Effort Is Invested In Primary And Secondary Outcome Data Collection In Trials. Chief Scientist Office of the Scottish Government’s Health & Social Care Directorate. 03/19-02/21. £224,213
8. Gillies K (CI), Locock L, Ahmed I. Narratives to support decisions about trial participation: investigation of purpose and content in reference to decision making. NHS Grampian. 04/18 – 04/19. £11,851
9. Maclennan S, Starr K, McClinton S, Clark T, Gillies K. Categorising heterogenity: the first step in developing a core outcome set for urolithiasis. NHS Grampian 04./18 – 04/19 £11,251
10. Gillies K, Hunn A, Knapp P, Entwistle V, Humphreys R, Campbell M. Feedback matters: How should trial results be reported back to participants? Academy of Medical Sciences - Springboard Scheme. 11/17-11/19. £99,940
11. Bower P, Sanders C, Planner C, Donnelly A, Turner K, Gillies K, Young B. Patient-centred trials: developing measures to improve the experience of people taking part in clinical trials. NIHR RfPB Programme.
12. Gillies K (CI), Treweek S, Bower P, Young B, Witham M, Wells M, Francis J. Developing theory based interventions to minimise drop-out in randomised trials. Chief Scientist Office of the Scottish Government’s Health & Social Care Directorate. 08/17 – 04/19. £249,649
13. Gillies K (CI), Cruickshank M, Newlands R, Brazelli M, Ahmed I. 'How' to measure outcomes defined as core for evaluating the effectiveness of interventions to treat uncomplicated symptomatic gallstone disease: generation of consensus based recommendations. 05/17-01/18. £11,905
14. Gillies K. Recruitment and retention in RCTs: qualitative explorations across and within trials. ISSF@Aberdeen - Women Returners Scheme. 08/16 – 02/17. £18,016
15. Ahmed I, Murchie P, Blazeby J, Avenell A, Hernandez R, Brazelli M, Gillies K, Norrie J, Ramsay C. . A randomised controlled trial comparing the clinical effectiveness and cost-effectiveness of laparoscopic cholecystectomy compared with observation/conservative management for preventing recurrent symptoms and complications in adults with uncomplicated symptomatic gallstones (C-Gall). NIHR HTA Programme. 03/16 – 08/20. £1,396,757
16. Gardner H, Gillies K, Treweek S. Putting research methodology into practice: producing useful evidence about trial recruitment strategies for trial designers and recruiters. Chief Scientist Office of the Scottish Governments Health and Social Care Directorate. 07/16-08/18. £26,322
17. Rae D, Miedzybrodzka Z, McKee L, Gillies K. Towards improvement in care delivery in Huntington’s Disease (HD): Improve HD. PhD Studentship (D Rae). Chief Scientist Office of the Scottish Governments Health and Social Care Directorate and Scottish Huntington’s Association. 10/15 – 10/18. £182,007
18. Gillies K (CI), Entwistle V, Treweek S, Campbell M. Evidence informed decision aids for clinical trial participation: a methodological investigation of core components and outcome measurements. Medical Research Council. Strategic Skills Fellowships – Methodology Research. £313,294. 2014-2018
19. Black M, Gillies K, Allan J, Bhattacharya S. Mode of delivery after Previous Caesarean Section: What long terms risks for offspring are yet to be identified, and how factors influence women’s preferred mode of delivery? Wellcome Trust. Research Training Fellowship (M Black). £220,774. Mar 2013-Mar 2016
20. Schumm K, Ramsay C, Skea Z, MacLennan S, N'Dow J, Campbell M. The acceptability and usefulness of a trial participation decision aid: a mixed methods study of patients and clinicians in the UK. Funded by a CSO Postdoctoral Fellowship in Health Services and Health of the Public Research (£167,776).
21. McClintonS,N'DowJ,BurrJ,MacLennanG, Kilonzo M, McMullan K, Schumm K, Lam TBL, BurgessN, Anson K, Preminger G, Pickard R, Patel U. Use of drug therapy in the management of symptomatic ureteric stones in hospitalised adults: multicente placebo controlled randomised trial of calcium channel blockers (nifedipine) and alpha blockers (tamsulosin) - The SUSPEND Trial. Funded by the NIHR HTA Programme (£1,450,240).
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