Protein appetite drives macronutrient-related differences in ventral tegmental area neural activity
Journal of Neuroscience
Contributions to Journals: Articles
Dr
Fabien
Naneix
PhD
Lecturer
- Overview
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Dr Fabien Naneix Contact Details
- fabien.naneix@abdn.ac.uk
- Address
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The University of Aberdeen
The Rowett Institute
Foresterhill
AB25 2ZD
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Biography
Fabien obtained his PhD in Neuroscience in 2012 from the University of Bordeaux (France) under the supervision of Dr Etienne Coutureau in the Decision and Adaptation team. During his PhD he investigated the role of the mesocortical dopamine pathway in goal-directed behaviour and its maturation during adolescence.
He stayed in Bordeaux for his first postdocs with Dr Martine Cador (Neuropsychopharmacology of Addiction team) and Dr Guillaume Ferreira (Laboratory of Nutrition and Integrative Neurobiology) to work on the long-term impact of sugar and high-fat diet overconsumption during adolescence on reward and memory processes.
In 2017, Fabien moved to the University of Leicester (England) to work as a postdoc with Dr James McCutcheon on the neurobiological circuits underlying protein appetite. In June 2020, Fabien is joining the Rowett Institute as Lecturer in Neuroscience.
Qualifications
PhD, Neuroscience University of Bordeaux 2012 MSc, Neuroscience and Neuropsychopharmacology University of Bordeaux 2008 BSc, Cellular Biology and Physiology University of Bordeaux 2006
External Memberships and Affiliations
Membership of professional Organisations
Société des Neurosciences (France)
European Brain and Behaviour Society (EEBS)
European Behavioural Pharmacology Society (EBPS)
British Neuroscience Association (BNA)
The Physiology Society
Society for Neuroscience
Prizes and Awards
The Royal Society - Research Grant (2021-2022), £20,000
- Research
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Research Areas
- Biomedical Sciences View Research Area
- Nutrition and Health View Research Area
Specialisms
- Animal Behaviour
- Neuroscience
- Nutrition
Our research specialisms are based on the Higher Education Classification of Subjects (HECoS) which is HESA open data, published under the Creative Commons Attribution 4.0 International
Research Overview
Developmental aspects of normal and pathological food related behaviours
Early stages of life (childhood, adolescence) represent critical vulnerability windows and previous work suggests that the exposure to external factors such as diet habits during development may alter cognitive and neurobiological maturation.
Current Research
Our research aims to investigate 1) how cognitive processes underlying food related behaviours and their neurobiological substrates are changing throughout development, and 2) how nutritional environment may affect these maturation processes and lead to pathological states, especially obesity and other food-related disorders.
To answer these questions we combine behavioural analyses (Pavlovian and instrumental conditioning) with in vivo recordings/manipulation of targeted brain circuits and ex vivo measures of brain function.
Research Funding and Grants
The Royal Society - Research Grant (2021-2022), £20,000
- Teaching
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Courses
- Publications
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Publications
Currently viewing:Page 1 of 1 Results 1 to 14 of 14
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Chemogenetic silencing of hippocampus and amygdala reveals a double dissociation in periadolescent obesogenic diet-induced memory alterations
Neurobiology of Learning and Memory, vol. 178, 107354
Contributions to Journals: Articles
- Digital Object Identifier
- https://doi.org/10.1016/j.nlm.2020.107354
- Additional Links
- View publication in Scopus
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Age-dependent effects of protein restriction on dopamine release
Neuropsychopharmacology, vol. 46, no. 2, pp. 394-403
Contributions to Journals: Articles
- Digital Object Identifier
- https://doi.org/10.1038/s41386-020-0783-z
- Additional Links
- View publication in Scopus
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Investigating the Effect of Physiological Need States on Palatability and Motivation Using Microstructural Analysis of Licking
Neuroscience, vol. 447, pp. 155-166
Contributions to Journals: Review articles
- Digital Object Identifier
- https://doi.org/10.1016/j.neuroscience.2019.10.036
- Additional Links
- View publication in Scopus
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No evidence that portion size influences food consumption in male Sprague Dawley rats
Physiology and Behavior, vol. 206, pp. 225-231
Contributions to Journals: Articles
- Digital Object Identifier
- https://doi.org/10.1016/j.physbeh.2019.04.013
- Additional Links
- View publication in Scopus
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Protracted motivational dopamine-related deficits following adolescence sugar overconsumption
Neuropharmacology, vol. 129, pp. 16-25
Contributions to Journals: Articles
- Digital Object Identifier
- https://doi.org/10.1016/j.neuropharm.2017.11.021
- Additional Links
- View publication in Scopus
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Impact of early consumption of high-fat diet on the mesolimbic dopaminergic system
eNeuro, vol. 4, no. 3, e0120-17.2017
Contributions to Journals: Articles
- Digital Object Identifier
- https://doi.org/10.1523/ENEURO.0120-17.2017
- Open Access
- http://aura.abdn.ac.uk/bitstream/2164/15814/1/Naniex_ENEURO_Impact_Early_Consumption_VOR.pdf
- Additional Links
- View publication in Scopus
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The effect of high-fat diet consumption on appetitive instrumental behavior in rats
Appetite, vol. 108, pp. 203-211
Contributions to Journals: Articles
- Digital Object Identifier
- https://doi.org/10.1016/j.appet.2016.10.001
- Additional Links
- View publication in Scopus
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Long-lasting deficits in hedonic and nucleus accumbens reactivity to sweet rewards by sugar overconsumption during adolescence
European Journal of Neuroscience, vol. 43, no. 5, pp. 671-680
Contributions to Journals: Articles
- Digital Object Identifier
- https://doi.org/10.1111/ejn.13149
- Additional Links
- View publication in Scopus
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Dissociable effects of anterior and mediodorsal thalamic lesions on spatial goal-directed behavior
Brain Structure and Function, vol. 221, pp. 79-89
Contributions to Journals: Articles
- Digital Object Identifier
- https://doi.org/10.1007/s00429-014-0893-7
- Additional Links
- View publication in Scopus
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Commentary: Cafeteria diet impairs expression of sensory-specific satiety and stimulus-outcome learning.
Frontiers in Psychology
Contributions to Journals: Articles
- Digital Object Identifier
- https://doi.org/10.3389/fpsyg.2015.00536
- Additional Links
- http://europepmc.org/abstract/med/25983710
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Adolescent stimulation of D2 receptors alters the maturation of dopamine-dependent goal-directed behavior.
Neuropsychopharmacology, vol. 38, no. 8, pp. 1566-1574
Contributions to Journals: Articles
- Digital Object Identifier
- https://doi.org/10.1038/npp.2013.55
- Additional Links
- http://europepmc.org/abstract/med/23443719
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Parallel maturation of goal-directed behavior and dopaminergic systems during adolescence.
The Journal of neuroscience : the official journal of the Society for Neuroscience, vol. 32, no. 46, pp. 16223-16232
Contributions to Journals: Articles
- Digital Object Identifier
- https://doi.org/10.1523/jneurosci.3080-12.2012
- Additional Links
- http://europepmc.org/abstract/med/23152606
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A role for medial prefrontal dopaminergic innervation in instrumental conditioning.
The Journal of neuroscience : the official journal of the Society for Neuroscience, vol. 29, no. 20, pp. 6599-6606
Contributions to Journals: Articles
- Digital Object Identifier
- https://doi.org/10.1523/jneurosci.1234-09.2009
- Additional Links
- http://europepmc.org/abstract/med/19458230
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