Dr Fabien Naneix
Fabien obtained his PhD in Neuroscience in 2012 from the University of Bordeaux (France) under the supervision of Dr Etienne Coutureau in the Decision and Adaptation team. During his PhD he investigated the role of the mesocortical dopamine pathway in goal-directed behaviour and its maturation during adolescence.
He stayed in Bordeaux for his first postdocs with Dr Martine Cador (Neuropsychopharmacology of Addiction team) and Dr Guillaume Ferreira (Laboratory of Nutrition and Integrative Neurobiology) to work on the long-term impact of sugar and high-fat diet overconsumption during adolescence on reward and memory processes.
In 2017, Fabien moved to the University of Leicester (England) to work as a postdoc with Dr James McCutcheon on the neurobiological circuits underlying protein appetite. In June 2020, Fabien is joining the Rowett Institute as Lecturer in Neuroscience.
- PhD Neuroscience2012 - University of Bordeaux
- MSc Neuroscience and Neuropsychopharmacology2008 - University of Bordeaux
- BSc Cellular Biology and Physiology2006 - University of Bordeaux
Membership of professional Organisations
Société des Neurosciences (France)
European Brain and Behaviour Society (EEBS)
European Behavioural Pharmacology Society (EBPS)
British Neuroscience Association (BNA)
The Physiology Society
Prizes and Awards
2019- EBBS 2019 Travel award (Elsevier-Brain and Behaviour Research)
2019- The Physiology Society travel award
2018- Research Leadership Programme, University of Leicester.
2017- Postdoc Prize talk (Dept. of Neuroscience, Psychology and Behaviour, University of Leicester)
Developmental aspects of normal and pathological food related behaviours
Control of food intake in a dynamic environment requires complex cognitive processes integrating internal and external information to support approach and food-seeking behaviours.
Early stages of life (childhood, adolescence) represent critical vulnerability windows and previous work suggests that the exposure to external factors such as diet habits during development may alter cognitive and neurobiological maturation.
Nutrition and Health
Our research aims to investigate 1) how cognitive processes underlying food related behaviours and their neurobiological substrates are changing throughout development, and 2) how nutritional environment may affect these maturation processes and lead to pathological states, especially obesity and other food-related disorders.
To answer these questions we combine behavioural analyses (Pavlovian and instrumental conditioning) with in vivo recordings/manipulation of targeted brain circuits and ex vivo measures of brain function.
Explorathon 21 (Aberdeen Science Centre Takeover)
Funding and Grants
The Royal Society - Research Grant (2021-2022)
Wellcome Trust Institutional Strategic Support Fund - ISSF (2021)
The Tenovus Scotland - Small Pilot Grant (2021-2022)
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Protein appetite drives macronutrient-related differences in ventral tegmental area neural activityJournal of Neuroscience, vol. 41, no. 23, pp. 5080-5092Contributions to Journals: Articles
Chemogenetic silencing of hippocampus and amygdala reveals a double dissociation in periadolescent obesogenic diet-induced memory alterationsNeurobiology of Learning and Memory, vol. 178, 107354Contributions to Journals: Articles
Age-dependent effects of protein restriction on dopamine releaseNeuropsychopharmacology, vol. 46, no. 2, pp. 394-403Contributions to Journals: Articles
Investigating the Effect of Physiological Need States on Palatability and Motivation Using Microstructural Analysis of LickingNeuroscience, vol. 447, pp. 155-166Contributions to Journals: Review articles
No evidence that portion size influences food consumption in male Sprague Dawley ratsPhysiology and Behavior, vol. 206, pp. 225-231Contributions to Journals: Articles
Protracted motivational dopamine-related deficits following adolescence sugar overconsumptionNeuropharmacology, vol. 129, pp. 16-25Contributions to Journals: Articles
Impact of early consumption of high-fat diet on the mesolimbic dopaminergic systemeNeuro, vol. 4, no. 3, e0120-17.2017Contributions to Journals: Articles
The effect of high-fat diet consumption on appetitive instrumental behavior in ratsAppetite, vol. 108, pp. 203-211Contributions to Journals: Articles
Long-lasting deficits in hedonic and nucleus accumbens reactivity to sweet rewards by sugar overconsumption during adolescenceEuropean Journal of Neuroscience, vol. 43, no. 5, pp. 671-680Contributions to Journals: Articles
Dissociable effects of anterior and mediodorsal thalamic lesions on spatial goal-directed behaviorBrain Structure and Function, vol. 221, pp. 79-89Contributions to Journals: Articles