Professor Bernadette Connolly
Professor Bernadette Connolly
BSc (Hons), PhD
Personal Chair
- About
-
Room 4.31
Institute of Medical Sciences
University of Aberdeen
Aberdeen
AB25 2ZD
Scotland, UKBiography
University of Aberdeen (1999 - present) Personal Chair
Deputy Director, Institute of Medical Sciences (2015 - 2021)
Director of College of Life Sciences & Medicine Graduate School (2007 - 2016)
University of Bern, Switzerland, Group Leader (1994-1999) and Marie-Heim Vögtlin Fellow (1997-1999)
Post-doctoral Researcher, Imperial College London (1990-1993)
Post-doctoral Researcher, Imperial Cancer Research Fund (1987-1990)
Post-doctoral Researcher, Brandeis University, Massachusetts (1983-1987)
PhD (Genetics), Trinity College Dublin, Ireland (1984)BSc (Hons), NUI Maynooth, Ireland (1980)
Qualifications
- BSc Biology & Chemistry1980 - NUI Maynooth
- PhD Genetics1984 - Trinity College Dublin
Memberships and Affiliations
- Internal Memberships
-
- External Memberships
-
Member of the International Commission on Trichinellosis since 2007
EASTBIO-BBSC Doctoral Training Partnership, Deputy Academic Lead (2012 – 2020)
University of Bristol; External Examiner, MRes Programme (2017 – 2021)
University of Southern Denmark, Faculty of Health Sciences; International Evaluation Panel of the Graduate School (2016)
University of Edinburgh, School of Biological Sciences; Review Panel for the Postgraduate Programmes (2010)
University of Newcastle, Medical Sciences Graduate School; Internal Subject Review of Postgraduate Taught Programmes (2011)
Imperial College London, Department of Life Sciences; Periodic Review of Postgraduate Masters’ Courses (2013)
University of Edinburgh, College of Medicine and Veterinary Medicine Postgraduate Taught Programme validation panel (2011- 2014)
MASTS Graduate School Steering Committee (2010 - 2015)
Vitae Scotland & Northern Ireland Hub Advisory Group (2007 - 2014)
- Research
-
Research Overview
I am interested in the biology of nematodes, with a particular interest in parasitic species. I collaborate with Profs Jonathan Pettitt and Berndt Muller to investigate the mechanism of spliced-leader trans-splicing in nematodes and with a view to exploiting this as a target for novel anthelmintics.
For more information on specific projects have a look at The Aberdeen Worm Lab webpage: (https://www.aberdeenwormlab.org/).
Research Areas
Accepting PhDs
I am currently accepting PhDs in Biomedical Sciences.
Please get in touch if you would like to discuss your research ideas further.
Research Specialisms
- Genetics
- Molecular Biology
- Parasitology
Our research specialisms are based on the Higher Education Classification of Subjects (HECoS) which is HESA open data, published under the Creative Commons Attribution 4.0 International licence.
- Teaching
-
- Publications
-
Page 1 of 4 Results 1 to 10 of 31
A novel, essential trans-splicing protein connects the nematode SL1 snRNP to the CBC-ARS2 complex
Nucleic Acids Research, vol. 50, no. 13, pp. 7591-7607Contributions to Journals: ArticlesResolution of polycistronic RNA by SL2 trans-splicing is a widely-conserved nematode trait
RNA , vol. 26, no. 12, pp. 1891-1904Contributions to Journals: Articles- [ONLINE] DOI: https://doi.org/10.1261/rna.076414.120
- [ONLINE] View publication in Scopus
A high-throughput screen for the identification of compounds that inhibit nematode gene expression by targeting spliced leader trans-splicing
International Journal for Parasitology: Drugs and Drug Resistance, vol. 10, pp. 28-37Contributions to Journals: Articles- [ONLINE] DOI: https://doi.org/10.1016/j.ijpddr.2019.04.001
- [OPEN ACCESS] http://aura.abdn.ac.uk/bitstream/2164/12209/1/A_high_throughput_screen_for_the_identification_of_compounds_that_inhibit_nematode_gene_expression_by_targeting_spliced_leader_trans_splicing.pdf
- [ONLINE] View publication in Scopus
- [ONLINE] View publication in Mendeley
An in vivo genetic screen for genes involved in spliced leader trans-splicing indicates a crucial role for continuous de novo spliced leader RNP assembly
Nucleic Acids Research, vol. 45, no. 14, pp. 8474-8483Contributions to Journals: ArticlesOperons Are a Conserved Feature of Nematode Genomes
Genetics, vol. 197, no. 4, pp. 1201-1211Contributions to Journals: Articles- [ONLINE] http://www.genetics.org/content/197/4/1201.full
- [ONLINE] DOI: https://doi.org/10.1534/genetics.114.162875
SL2-like spliced leader RNAs in the basal nematode Prionchulus punctatus: new insight into the evolution of nematode SL2 RNAs
RNA , vol. 16, no. 8, pp. 1500-1507Contributions to Journals: Articles- [ONLINE] DOI: https://doi.org/10.1261/rna.2155010
The evolution of spliced leader trans-splicing in nematodes
Biochemical Society Transactions, vol. 38, no. 4, pp. 1125-1130Contributions to Journals: Articles- [ONLINE] DOI: https://doi.org/10.1042/BST0381125
Cloning and analysis of a Trichinella pseudospiralis muscle larva secreted serine protease gene
Veterinary Parasitology, vol. 159, no. 3-4, pp. 268-271Contributions to Journals: Articles- [ONLINE] DOI: https://doi.org/10.1016/j.vetpar.2008.10.036
Micro-environmental conditions modulate protein secretion and infectivity of the Trichinella spiralis L1 larva
Veterinary Parasitology, vol. 159, no. 3-4, pp. 236-239Contributions to Journals: Articles- [ONLINE] DOI: https://doi.org/10.1016/j.vetpar.2008.10.049
Spliced leader trans-splicing in the nematode Trichinella spiralis uses highly polymorphic, noncanonical spliced leaders
RNA , vol. 14, no. 4, pp. 760-770Contributions to Journals: Articles- [ONLINE] DOI: https://doi.org/10.1261/rna.948008
