Dr Nicola Mutch

Dr Nicola Mutch
BSc (Hons), Molecular and Cellular Biology; PhD, Thrombosis & Haemostasis

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I am currently accepting PhDs in Biomedical Sciences.

Overview
Dr Nicola Mutch
Dr Nicola Mutch

Contact Details


Biography

Education

University of Aberdeen, Department of Molecular and Cellular Biology and Department of Medince and Therapeutics. Aberdeen, UK.                                                                                                 PhD in Haemostasis & Vascular Biology (1997-2000). Supervisor Dr Nuala A Booth. Funded by ACTR.

University of Aberdeen, Aberdeen, UK.                                                                                     BSc (Hons) (1993-1997) in Molecular and Cellular Biology.

Employment

2016: Senior Lecturer, University of Aberdeen, School of Medicine, Medical Sciences and Nutrition.  Insitute of Medical Sciences, (IMS).

2011-2016: British Heart Foundation Fellow, Senior Research Fellow, School of Medicine and Dentistry, IMS.

2010-2011: Research Fellow funded by British Heart Foundation, School of Medicine and Dentistry, IMS.

2007-2010: Tenure-track Independent Research Fellow in Cardiovascular Medicine, Department of BIological Sciences, University of Leeds, Leeds, UK.

2004-2006: Postdoctoral research associate, University of Illinois at Urbana-Champaign, Department of Medicine, Champaign, Illinois, USA.

2001-2003: Postdoctoral research fellow, Department of Molecular and Cellular Biology, University of Aberdeen, UK.             

 


Qualifications

PhD, Thrombosis & Vascular Biology University of Aberdeen 2001
BSc hons, Molecular Biology University of Aberdeen 1997

Latest Publications

  • Monocytes Expose Factor XIII-A and Stabilize Thrombi against Fibrinolytic Degradation

    Alshehri, F. S. M., Whyte, C. S., Tuncay, A., Williams, M., Wilson, H. M., Mutch, N. J.

  • Trauma-induced coagulopathy

    Moore, E. E., Moore, H. B., Kornblith, L. Z., Neal, M. D., Hoffman, M., Mutch, N., Schöchl, H., Hunt, B. J., Sauaia, A.

  • A serpin with a finger in many PAI’s: PAI-1’s central function in thromboinflammation and cardiovascular disease

    Morrow, G. B., Whyte, C., Mutch, N. J.

  • Factor XIII-A: An Indispensable “Factor” in Haemostasis and Wound Healing

    Alshehri, F. S. M., Whyte, C., Mutch, N.

  • Fibrinogen Replacement Therapy for Traumatic Coagulopathy: Does the Fibrinogen Source Matter?

    Morrow, G. B., Carlier, M. S. A., Dasgupta, S., Craigen, F. B., Mutch, N. J., Curry, N.

View all Publications
Research

Research Areas

Please get in touch if you would like to discuss your research ideas further.

Email Me

Specialisms

  • Biological Sciences
  • Cardiology
  • Cell Biology
  • Human Biology
  • Immunology

Our research specialisms are based on the Higher Education Classification of Subjects (HECoS) which is HESA open data, published under the Creative Commons Attribution 4.0 International


Current Research

POST-DOC

Dr Claire Whyte

BHF funded post-doc (Dec 2015-May 2019).  Claire has been in the lab since January 2011 and is on her second BHF-funded project grant.  Claire is currently working on the role of platelet-derived plasmiongen in driving local fibrinolysis.  

CURRENT PhD STUDENTS

Mohammad Jalal: Start date 01/12/2012; Funded by the Saudi Arabian Government. 4 year PhD.

Paraskevi Untiveros: Start date 01/09/2014; Funded by the Chief Scientist Office. Clinical Fellow 3 year PhD.

Gael Morrow: Start date 12/01/2015; Funded by the British Society of Haemostasis and Thrombosis, British Society of Haematology and Lifeblood.  3 Year PhD.

Maria-Louise Williams: Start date 01/10/16; Funded by the Institute of Medical Sciences, University of Aberdeen. 3 year PhD.

LAB ALLUMNI

Mrs Ausra Lionikiene. Ausra was employed a research technician on my BHF-funded fellowship and studying the biological significance of factor XII.  Ausra was an integral member of the team organising the lab, finances and all the personnel.  


Supervision

My current supervision areas are: Biomedical Sciences.


Research Funding and Grants

CURRENT GRANTS

1. British Heart Foundation Project Grant PI: NJ Mutch (Dec 2015-Dec 2018) 'Platelet plasminogen as a driver of local fibrinolysis'

2. British Society of Haematology / Lifeblood / British Society of Thrombosis & Haemostasis PhD Studentship PI: NJ Mutch; Co-I CS Whyte (Jan 2015-Jan 2018) 'The impact of thrombus composition on regulation of fibrinolysis under flow'

4. Friends of Anchor PI: Dr Paraskevi UntiverosCo-I Dr Nicola J Mutch, Dr Henry Watson (Aug 2016-Aug 2017) The role of ABO blood group in thrombosis

5. Chief Scientist Office, Scottish Government Fellow: P Untiveros; Supervisors: NJ Mutch, H Watson ''Influence of Anaemia on Clot Structure'

6. Friends of Anchor PI: NJ Mutch (Apr 2015-Nov 2016) 'A functional role of platelet FXIII-A in clot retraction'

RECENT GRANTS

1. British Heart Foundation Basic Science Fellowship Fellow: NJ Mutch (Mar 2011-Mar 2016 Includes two maternity leaves) 'Characterising the physiological role of factor XII and the contact system'

2. British Heart Foundation Project Grant PI: NJ Mutch; Co-I: RAS Ariëns (Jan 2012-Dec 2015) 'Changes in fibrin clot structure and susceptibility to lysis induced by polyphosphate'

3. Aberdeen Development Trust PhD Studentship PI: NJ Mutch (Oct 2012-Apr 2016) 'The antifibrinolytic function of factor XIII'

4. Chest, Heart and Stroke Scotland PI Isobel Ford Co-I NJ Mutch, MJ McLeod. () Responsiveness to thrombolytic therapy of for Ischaemic stroke

5. British Heart Foundation Project Grant (PG/07/122/23480). PI: NJ Mutch (Jun 2008-Oct 2012) 'Polyphosphate as a physiological surface for contact activation
'

Teaching

Courses


Teaching Responsibilities

Course coordinator for BM5003 Cardiovascular Health and Disease

Publications

Publications 

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