The Institute of Applied Health Sciences

Professor Siladitya Bhattacharya

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Professor Siladitya Bhattacharya
Professor Siladitya Bhattacharya
Professor Siladitya Bhattacharya

MD, FRCOG

Sir Dugald Baird Chair in Women's Health

About
Email Address
s.bhattacharya@abdn.ac.uk
School/Department
School of Medicine, Medical Sciences and Nutrition

Qualifications

  • MD Obstetrics and GYnaecology 
    1997 - University of Aberdeen 
  • MRCOG Obstetrics and GYnaecology 
    1991 - Royal College of Obstetricians and Gynaecologists 
  • FRCOG Obstetrics and GYnaecology 
    2006 - Royal College of Obstetricians and Gynaecologists 
  • Subspecialty Accreditation Reproductive Medicine 
    1999 - Royal College of Obstetricians & Gynaecologists 

Memberships and Affiliations

Internal Memberships

As Vice-Principal for Global Engagement from 2024-26 Prof Bhattacharya had strategic oversight over the Institution’s strategy for student recruitment and strong and sustainable international partnerships. Previously Head of the School of Medicine, Medical Sciences and Nutrition from 2018, he is a Chair in Women Health and Chief Investigator on a portfolio of medical trials and has served on several national and international committees relating to reproductive medicine.

 

External Memberships
  • Member, Medical Schools Council (2018- 24)
  • Non-executive member NHS Grampian Health Board (2019-24)
  • NHS Research Scotland Clinical Research Champion for Women’s Health and Childbearing Scotland 2015-18)
  • Chair, Reproductive Medicine Clinical Studies Group (RCOG), the National Reproductive Health Research Network UK (2008-2014)
  • Specialty Lead for Reproductive Health and Childbirth (Scotland) (2009-14)
  • Member, Health Services and Population Health Research Committee, Chief Scientist Office Scotland (2006-12) 
  • Member, Panel for Chief Scientist Office Scotland Clinical Academic Fellowships (2013-18)
  • Member, College of Experts, Medical Research Council (2006-09)
  • Member Core Outcome Measures for Infertility Trials (COMMIT) working group when?
  • Chair International Network for research in Reproductive Medicine (INREM) (2013-)
  • Chair (2015-16) International Federation of Obstetrics and Gynaecology (FIGO) Reproductive Medicine Committee
  • Co-Chair (2009 - 15) International Federation of Obstetrics and Gynaecology (FIGO) Reproductive Medicine Committee
  • Member Standards and Practice Committee for the International Federation of Fertility Societies (IFFS) (2007-)
  • Member European IVF Monitoring Committee Board (European Society for Human Reproduction and Embryology) (ESHRE) (2007 - 2013)
  • Quality Control (Auditor) for FIVNAT (Swiss Society for Reproductive Medicine) (2010 – 12)

 

JOURNAL EDITORSHIPS

  • Editor-in-Chief Human Reproduction Open (2017-22)
  • Editor: Cochrane Collaboration Gynaecology and Fertility (2004 -20)
  • Scientific Editor:  BJOG: An International Journal of Obstetrics and Gynaecology (2003-5)
  • Editor: The Obstetrician and Gynaecologist (2003-5)
  • Associate Editor Human Reproduction Update (2011 - 2015)
  • Academic Editor PLOS ONE (2014 - 16)

Prizes and Awards

  • MRCOG Prize medal, Royal College of Obstetricians and Gynaecologists 1991
  • European Society of Reproduction and Embryology Established Clinician Award 2000
  • Wellcome Trust Research Leave Award 2002-7
  • The Obstetrical & Gynaecological Society of Malaysia & Royal College of Obstetricians & Gynaecologists (RCOG-OGSM) Travelling Fellowship 2015
  • Seelye Travelling Fellowship, University of Auckland Foundation 2018
Research

Research Overview

  • Health services research in reproductive health
  • Epidemiology of reproductive health
  • Systematic reviews
  • Randomised trials

Current Research

My main research interests include epidemiology of infertility, evaluation of clinical and cost effectiveness of interventions and delivery of care in reproductive medicine. In addition to infertility and assisted reproduction, my clinical areas of interest include early pregnancy loss, caesarean section heavy menstrual bleeding, pelvic pain and endometriosis.

To date my research has involved a programme of interlinked projects funded by Wellcome Trust, the Chief Scientist Office Scotland, Medical Research Council and National Institute of Health Research (NIHR) UK. My projects have included studies on the prevalence and reproductive outcomes in women with infertility and early pregnancy loss, systematic (Cochrane) reviews, individual patient data meta-analysis, multi-centre randomised controlled trials and studies on the cost effectiveness of interventions in infertility and heavy menstrual bleeding.

Collaborations

I  collaborate extensively with trialists, epidemiologists and health services researchers nationally as well as internationally. I lead INREM -(International Reproductive Medicine Research Network), a global consortium for collaborative research and have extensive national  and international collaborations.

 

Supervision

  • I have supervised 10 post graduate research students to completion and currently co-supervise 2 PhD students.

Funding and Grants

  • A randomised trial of relugolix combination therapy versus usual medical treatment in the medical management of heavy menstrual bleeding (RESPONSIBLE) Bhattacharya S, Critchley HOD, Maclennan G, et al.. 2025-29 NIHR Health Technology Assessment (HTA) £1,956,95
  • Hormone therapy for premature ovarian insufficiency: randomised trial and long-term evaluation (POISE) Davies M, Daniels J, Bhattacharya S, et al..NIHR HTA 2012-34 £2,263,669
  • Recurrence of Endometriosis: a randomised controlled trial of clinical and cost-effectiveness of Gonadotrophin Releasing Hormone Analogues with add-back hormone replacement therapy versus repeat Laparoscopic surgery (REGAL) Saraswat L, Bhattacharya S, Cooper K, MacLennan G, et al.  NIHR HTA 2019-23 £1,711,863
  • Letrozole or Clomifene, with or without metformin, for ovulation induction in women with polycysticovary syndrome: a 2x2 factorial design randomised trial (The LOCI trial) Coomarasamy A, Sunkara S, Gallos I, Bhattacharya S, et al NIHR HTA (2019-22). £2,136,177 (2019 -22)
  • Effects and Safety of Testosterone in Men with Low Testosterone levels: an evidence synthesis andeconomic evaluation. The TESTES (Testosterone Effects and Safety) Consortium. Jayasena C, Bhattacharya S, Gillies K, Hernandez R, Aucott L, Quinton R, Wu F, Oliver N, Dhillo W. NIHR HTA (2018-20) £508,668
  • Surgery for women with endometrioma prior to IVF- Assessing the feasibility of a multicentre randomised trial in UK (SEND) Maheshwari A, Bhattacharya S, Cooper K, Saraswat L, Horner, Gillies K, Breeman S, Burns GNHS Grampian R & D Pump priming Grant (2018-19) £24,995
  • Perinatal outcomes of singletons born following in-vitro fertilisation: a comparison of different embryo transfer strategies using UK data. Mclernon D, Bhattacharya S, Maheshwari A, Raja EA. NHS Grampian Endowments. (2018-19) £10,071
  • A population-based matching study to estimate the benefit of in-vitro fertilisation (IVF) for infertility McLernon D, van Geloven N, van Eekelen R & Bhattacharya S Tenovus Scotland (2017-18) £11,438
  • Environmental determinants of IVF treatment Clemens T, Docherty R, Dibben C, Stock S, Bhattacharya S. NERC/ MRC/ CSO (2016-17 - 18) £51,390 
  • Is a combination of methotrexate and gefitinib more effective than methotrexate alone as a treatment for ectopic pregnancy? – a randomised placebo controlled trial (GEM3)AW Horne, S Tong, WC Duncan, J Daniels, A Coomaraswamy, L Middleton, A Peace-Gadsby, T Bourne, D Jurkovic, S Bhattacharya, C Bottomley. National Institute for Health Research (NIHR) Efficacy and mechanism programme (EME) (2016-19) £999,811
  • Elective freezing of embryos in assisted conception (E-FREEZE) -  Maheshwari A, Bhattacharya S, Macklon N, Coomarasamy A, Khalaf Y, Lavery S, Fenning N, Juzzak E, Kurinczuk J. National Institute for Health Research (NIHR) Health Technology Assessment (HTA) programme. (2015-19) £1,400,000.
  • A multi-centre randomised controlled trial of the efficacy and mechanism of action of gabapentin for the management of chronic pelvic pain in women.  Horne A, Daniels J, Vincent K, Cheong Y, Middleton L, Collett B, Bhattacharya S, Tracey I, Williams A, (2015-18) £1,425,969.  
  • Ulipristal acetate versus conventional management of heavy menstrual bleeding (HMB: including uterine fibroids): a randomised controlled trial and exploration of mechanism of action (UCON trial). Critchley H, Bhattacharya S, Clark J, Daniels J, Middleton L et al.   National Institute for Health Research (NIHR) Efficacy and mechanism programme (EME) (2014-18)£1,584,094
  • . 
  • A multicentre randomised controlled trial comparing laparoscopic supra-cervical hysterectomy with second generation endometrial ablation for the treatment of heavy menstrual bleeding (HEALTH).  Bhattacharya S (Co CI), Cooper K (Co CI), Clark J, Hawe J, Phillips K, Hawthorne R, Norrie J, Cook J, Scotland G, McCormack K.  National Institute for Health Research (NIHR) Health Technology Assessment (HTA) programme (2014-18) £1,307,643
  • Improving Intrapartum outcomes for mothers and babies in Scotland: A stepped wedge RCT of an intrapartum emergencies training package in 12 Scottish Maternity Units (THISTLE). Bhattacharya S, Draycott T, Fox R, Siassakos D, Lenguerrand E, Lynch P, Crofts J, Winter C, Norrie J, MacLennan G, McCormack K, McDonald A, McPherson G, Cameron A.  Chief Scientist Office Scotland (2013-16) £200,045
  • Preventing recurrence of endometriosis by means of long acting progestogen therapy; (PreEmPT).  Bhattacharya S, Daniels J, Gupta J, Clark J, Cooper K, Horne A, Critchley H, Sarotigan E, Prentice A, Becker C, Jones G, Denny E., Whittal C.  National Institute for Health Research (NIHR) Health Technology Assessment (HTA) programme (2013-18) £1,961,118.
  • Selection of sperm for assisted reproductive treatment by prior hyaluronic acid binding: increasing live birth outcomes and reducing miscarriage rates (Hyaluronic Assisted Binding Sperm Selection; HABSelect). Miller D, Pavitt S, Coomarasamy A, Pacey AA, Bhattacharya S, Brison D, Lewis S, Hooper R, Edwards L, West R, Khalaf Y, Sebatani L.   NIHR efficacy and mechanism evaluation (EME) programme (2012-16) £1,427,328
  • Development and validation of prognostic models for subfertility.  CSOPost doctoral Fellowship.  Awarded to Dr David. McLernon. Supervisors: Lee A, Bhattacharya S.  Chief Scientist Office Scotland (2013-16) £ 172,515
  • Long term health of women diagnosed with endometriosis: a Scottish record linkage study. Bhattacharya S, Cooper K, Horne A, Bhattacharya S, Saraswat L. Ayansina D. Chief Scientist Office Scotland (2012-14) £117,758

 

Publications

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  • In vitro maturation in subfertile women with polycystic ovarian syndrome undergoing assisted reproduction

    Siristatidis, C. S., Vrachnis, N., Creatsa, M., Maheshwari, A., Bhattacharya, S.
    Cochrane Database of Systematic Reviews, no. 10, CD006606
    Contributions to Journals: Articles

  • IVF for unexplained infertility

    Pandian, Z., Bhattacharya, S.
    Human Reproduction Update, vol. 19, no. 5, pp. 431
    Contributions to Journals: Articles

  • Maternal obesity during pregnancy and premature mortality from cardiovascular event in adult offspring: follow-up of 1 323 275 person years

    Reynolds, R. M., Allan, K. M., Raja, E. A., Bhattacharya, S., McNeill, G., Hannaford, P. C., Sarwar, N., Lee, A. J., Bhattacharya, S., Norman, J. E.
    British Medical Journal, vol. 347, no. -, f4539
    Contributions to Journals: Articles

  • Number of embryos for transfer following in vitro fertilisation or intra-cytoplasmic sperm injection

    Pandian, Z., Marjoribanks, J., Ozturk, O., Serour, G., Bhattacharya, S.
    Cochrane Database of Systematic Reviews, vol. 7, CD003416
    Contributions to Journals: Articles

  • Phase II single arm open label multicentre clinical trial to evaluate the efficacy and side effects of combination gefitinib and methotrexate to treat ectopic pregnancies (GEM II): study protocol

    Horne, A. W., Skubisz, M. M., Doust, A., Duncan, W. C. D., Wallace, E., Critchley, H. O. D., Johns, T. G., Norman, J. E., Bhattacharya, S., Mollison, J., Rassmusen, M., Tong, S.
    BMJ Open, vol. 3, no. 7, e002902
    Contributions to Journals: Articles

  • Failures (with some successes) of assisted reproduction and gamete donation programs

    Baird, D. T., Bhattacharya, S., Devroey, P., Diedrich, K., Evers, J. L. H., Fauser, B. C. J. M., Jouannet, P., Pellicer, A., Walters, E., Crosignani, P. G., Fraser, L., Geraedts, J. P. M., Gianaroli, L., Glasier, A., Liebaers, I., Sunde, A., Tapanainen, J. S., Tarlatzis, B., Van Steirteghem, A., Veiga, A.
    Human Reproduction Update, vol. 19, no. 4, pp. 354-365
    Contributions to Journals: Articles

  • Counselling in the context of fertility and cancer: some sociological insights

    Barbour, R. S., Porter, M. A., Peddie, V. L., Bhattacharya, S.
    Human Fertility, vol. 16, no. 1, pp. 54-58
    Contributions to Journals: Articles

  • Steroidogenic enzyme expression in the human fetal liver and potential role in the endocrinology of pregnancy

    O'Shaughnessy, P. J., Monteiro, A., Bhattacharya, S., Fraser, M. J., Fowler, P. A.
    Molecular Human Reproduction, vol. 19, no. 3, pp. 177-187
    Contributions to Journals: Articles

  • Fertility (update): summary of NICE guidance

    Fields, E., Chard, J., James, D., Treasure, T., Bhattacharya, S.
    British Medical Journal, vol. 346, f650
    Contributions to Journals: Articles

  • Elective frozen replacement cycles for all: ready for prime time?

    Maheshwari, A., Bhattacharya, S.
    Human Reproduction, vol. 28, no. 1, pp. 6-9
    Contributions to Journals: Articles
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