Professor Siladitya Bhattacharya

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Professor Siladitya Bhattacharya
Professor Siladitya Bhattacharya
Professor Siladitya Bhattacharya

MD, FRCOG

Sir Dugald Baird Chair in Women's Health

About

Qualifications

  • MD Obstetrics and GYnaecology 
    1997 - University of Aberdeen 
  • MRCOG Obstetrics and GYnaecology 
    1991 - Royal College of Obstetricians and Gynaecologists 
  • FRCOG Obstetrics and GYnaecology 
    2006 - Royal College of Obstetricians and Gynaecologists 
  • Subspecialty Accreditation Reproductive Medicine 
    1999 - Royal College of Obstetricians & Gynaecologists 

Memberships and Affiliations

Internal Memberships

As Vice-Principal for Global Engagement from 2024-26 Prof Bhattacharya had strategic oversight over the Institution’s strategy for student recruitment and strong and sustainable international partnerships. Previously Head of the School of Medicine, Medical Sciences and Nutrition from 2018, he is a Chair in Women Health and Chief Investigator on a portfolio of medical trials and has served on several national and international committees relating to reproductive medicine.

 

External Memberships
  • Member, Medical Schools Council (2018- 24)
  • Non-executive member NHS Grampian Health Board (2019-24)
  • NHS Research Scotland Clinical Research Champion for Women’s Health and Childbearing Scotland 2015-18)
  • Chair, Reproductive Medicine Clinical Studies Group (RCOG), the National Reproductive Health Research Network UK (2008-2014)
  • Specialty Lead for Reproductive Health and Childbirth (Scotland) (2009-14)
  • Member, Health Services and Population Health Research Committee, Chief Scientist Office Scotland (2006-12) 
  • Member, Panel for Chief Scientist Office Scotland Clinical Academic Fellowships (2013-18)
  • Member, College of Experts, Medical Research Council (2006-09)
  • Member Core Outcome Measures for Infertility Trials (COMMIT) working group when?
  • Chair International Network for research in Reproductive Medicine (INREM) (2013-)
  • Chair (2015-16) International Federation of Obstetrics and Gynaecology (FIGO) Reproductive Medicine Committee
  • Co-Chair (2009 - 15) International Federation of Obstetrics and Gynaecology (FIGO) Reproductive Medicine Committee
  • Member Standards and Practice Committee for the International Federation of Fertility Societies (IFFS) (2007-)
  • Member European IVF Monitoring Committee Board (European Society for Human Reproduction and Embryology) (ESHRE) (2007 - 2013)
  • Quality Control (Auditor) for FIVNAT (Swiss Society for Reproductive Medicine) (2010 – 12)

 

JOURNAL EDITORSHIPS

  • Editor-in-Chief Human Reproduction Open (2017-22)
  • Editor: Cochrane Collaboration Gynaecology and Fertility (2004 -20)
  • Scientific Editor:  BJOG: An International Journal of Obstetrics and Gynaecology (2003-5)
  • Editor: The Obstetrician and Gynaecologist (2003-5)
  • Associate Editor Human Reproduction Update (2011 - 2015)
  • Academic Editor PLOS ONE (2014 - 16)

Prizes and Awards

  • MRCOG Prize medal, Royal College of Obstetricians and Gynaecologists 1991
  • European Society of Reproduction and Embryology Established Clinician Award 2000
  • Wellcome Trust Research Leave Award 2002-7
  • The Obstetrical & Gynaecological Society of Malaysia & Royal College of Obstetricians & Gynaecologists (RCOG-OGSM) Travelling Fellowship 2015
  • Seelye Travelling Fellowship, University of Auckland Foundation 2018
Research

Research Overview

  • Health services research in reproductive health
  • Epidemiology of reproductive health
  • Systematic reviews
  • Randomised trials

Current Research

My main research interests include epidemiology of infertility, evaluation of clinical and cost effectiveness of interventions and delivery of care in reproductive medicine. In addition to infertility and assisted reproduction, my clinical areas of interest include early pregnancy loss, caesarean section heavy menstrual bleeding, pelvic pain and endometriosis.

To date my research has involved a programme of interlinked projects funded by Wellcome Trust, the Chief Scientist Office Scotland, Medical Research Council and National Institute of Health Research (NIHR) UK. My projects have included studies on the prevalence and reproductive outcomes in women with infertility and early pregnancy loss, systematic (Cochrane) reviews, individual patient data meta-analysis, multi-centre randomised controlled trials and studies on the cost effectiveness of interventions in infertility and heavy menstrual bleeding.

Collaborations

I  collaborate extensively with trialists, epidemiologists and health services researchers nationally as well as internationally. I lead INREM -(International Reproductive Medicine Research Network), a global consortium for collaborative research and have extensive national  and international collaborations.

 

Supervision

  • I have supervised 10 post graduate research students to completion and currently co-supervise 2 PhD students.

Funding and Grants

  • A randomised trial of relugolix combination therapy versus usual medical treatment in the medical management of heavy menstrual bleeding (RESPONSIBLE) Bhattacharya S, Critchley HOD, Maclennan G, et al.. 2025-29 NIHR Health Technology Assessment (HTA) £1,956,95
  • Hormone therapy for premature ovarian insufficiency: randomised trial and long-term evaluation (POISE) Davies M, Daniels J, Bhattacharya S, et al..NIHR HTA 2012-34 £2,263,669
  • Recurrence of Endometriosis: a randomised controlled trial of clinical and cost-effectiveness of Gonadotrophin Releasing Hormone Analogues with add-back hormone replacement therapy versus repeat Laparoscopic surgery (REGAL) Saraswat L, Bhattacharya S, Cooper K, MacLennan G, et al.  NIHR HTA 2019-23 £1,711,863
  • Letrozole or Clomifene, with or without metformin, for ovulation induction in women with polycysticovary syndrome: a 2x2 factorial design randomised trial (The LOCI trial) Coomarasamy A, Sunkara S, Gallos I, Bhattacharya S, et al NIHR HTA (2019-22). £2,136,177 (2019 -22)
  • Effects and Safety of Testosterone in Men with Low Testosterone levels: an evidence synthesis andeconomic evaluation. The TESTES (Testosterone Effects and Safety) Consortium. Jayasena C, Bhattacharya S, Gillies K, Hernandez R, Aucott L, Quinton R, Wu F, Oliver N, Dhillo W. NIHR HTA (2018-20) £508,668
  • Surgery for women with endometrioma prior to IVF- Assessing the feasibility of a multicentre randomised trial in UK (SEND) Maheshwari A, Bhattacharya S, Cooper K, Saraswat L, Horner, Gillies K, Breeman S, Burns GNHS Grampian R & D Pump priming Grant (2018-19) £24,995
  • Perinatal outcomes of singletons born following in-vitro fertilisation: a comparison of different embryo transfer strategies using UK data. Mclernon D, Bhattacharya S, Maheshwari A, Raja EA. NHS Grampian Endowments. (2018-19) £10,071
  • A population-based matching study to estimate the benefit of in-vitro fertilisation (IVF) for infertility McLernon D, van Geloven N, van Eekelen R & Bhattacharya S Tenovus Scotland (2017-18) £11,438
  • Environmental determinants of IVF treatment Clemens T, Docherty R, Dibben C, Stock S, Bhattacharya S. NERC/ MRC/ CSO (2016-17 - 18) £51,390 
  • Is a combination of methotrexate and gefitinib more effective than methotrexate alone as a treatment for ectopic pregnancy? – a randomised placebo controlled trial (GEM3)AW Horne, S Tong, WC Duncan, J Daniels, A Coomaraswamy, L Middleton, A Peace-Gadsby, T Bourne, D Jurkovic, S Bhattacharya, C Bottomley. National Institute for Health Research (NIHR) Efficacy and mechanism programme (EME) (2016-19) £999,811
  • Elective freezing of embryos in assisted conception (E-FREEZE) -  Maheshwari A, Bhattacharya S, Macklon N, Coomarasamy A, Khalaf Y, Lavery S, Fenning N, Juzzak E, Kurinczuk J. National Institute for Health Research (NIHR) Health Technology Assessment (HTA) programme. (2015-19) £1,400,000.
  • A multi-centre randomised controlled trial of the efficacy and mechanism of action of gabapentin for the management of chronic pelvic pain in womenHorne A, Daniels J, Vincent K, Cheong Y, Middleton L, Collett B, Bhattacharya S, Tracey I, Williams A, (2015-18) £1,425,969.  
  • Ulipristal acetate versus conventional management of heavy menstrual bleeding (HMB: including uterine fibroids): a randomised controlled trial and exploration of mechanism of action (UCON trial). Critchley H, Bhattacharya S, Clark J, Daniels J, Middleton L et al.   National Institute for Health Research (NIHR) Efficacy and mechanism programme (EME) (2014-18)£1,584,094
  • A multicentre randomised controlled trial comparing laparoscopic supra-cervical hysterectomy with second generation endometrial ablation for the treatment of heavy menstrual bleeding (HEALTH).  Bhattacharya S (Co CI), Cooper K (Co CI), Clark J, Hawe J, Phillips K, Hawthorne R, Norrie J, Cook J, Scotland G, McCormack K.  National Institute for Health Research (NIHR) Health Technology Assessment (HTA) programme (2014-18) £1,307,643
  • Improving Intrapartum outcomes for mothers and babies in Scotland: A stepped wedge RCT of an intrapartum emergencies training package in 12 Scottish Maternity Units (THISTLE). Bhattacharya S, Draycott T, Fox R, Siassakos D, Lenguerrand E, Lynch P, Crofts J, Winter C, Norrie J, MacLennan G, McCormack K, McDonald A, McPherson G, Cameron A.  Chief Scientist Office Scotland (2013-16) £200,045
  • Preventing recurrence of endometriosis by means of long acting progestogen therapy; (PreEmPT).  Bhattacharya S, Daniels J, Gupta J, Clark J, Cooper K, Horne A, Critchley H, Sarotigan E, Prentice A, Becker C, Jones G, Denny E., Whittal C.  National Institute for Health Research (NIHR) Health Technology Assessment (HTA) programme (2013-18) £1,961,118.
  • Selection of sperm for assisted reproductive treatment by prior hyaluronic acid binding: increasing live birth outcomes and reducing miscarriage rates (Hyaluronic Assisted Binding Sperm Selection; HABSelect). Miller D, Pavitt S, Coomarasamy A, Pacey AA, Bhattacharya S, Brison D, Lewis S, Hooper R, Edwards L, West R, Khalaf Y, Sebatani L.   NIHR efficacy and mechanism evaluation (EME) programme (2012-16) £1,427,328
  • Development and validation of prognostic models for subfertility.  CSOPost doctoral Fellowship.  Awarded to Dr David. McLernon. Supervisors: Lee A, Bhattacharya S.  Chief Scientist Office Scotland (2013-16) £ 172,515
  • Long term health of women diagnosed with endometriosis: a Scottish record linkage study. Bhattacharya S, Cooper K, Horne A, Bhattacharya S, Saraswat L. Ayansina D. Chief Scientist Office Scotland (2012-14) £117,758

 

Publications

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  • Can history, ultrasound, or ELISA chlamydial antibodies, alone or in combination, predict tubal factor infertility in subfertile women?

    Logan, S., Gazvani, R., McKenzie, H., Templeton, A. A., Bhattacharya, S.
    Human Reproduction, vol. 18, no. 11, pp. 2350-2356
    Contributions to Journals: Articles
  • Does Caesarean section cause infertility?

    Porter, M. A., Bhattacharya, S., Van Teijlingen, E. R., Templeton, A. A.
    Human Reproduction, vol. 18, no. 10, pp. 1983-1986
    Contributions to Journals: Articles
  • Interventions of ‘Poor responders’ to Controlled Ovarian Hyperstimulation (COH) in In-vitro Fertilisation (IVF)” (Protocol)

    Shanbhag, S., McTavish, A., Bhattacharya, S., Hamilton, M., Mollison, J.
    Cochrane Database of Systematic Reviews, no. 3, CD004379
    Contributions to Journals: Articles
  • Caesarean section and subfertility (multiple letters)

    Porter, M., Bhattacharya, S., Murphy, D. J., Stirrat, G. M., Heron, J.
    Human Reproduction, vol. 18, no. 1, pp. 217-218
    Contributions to Journals: Letters
  • Clomiphene Citrate - A review of its current status (Review)

    Shanbhag, S., Bhattacharya, S.
    The Journal of Obstetrics and Gynecology of India, vol. 53, no. 2, pp. 127-130
    Contributions to Journals: Articles
  • Effective use of assisted reproduction

    Bhattacharya, S.
    Human Fertility, vol. 6, no. 2 Suppl, pp. S60-62
    Contributions to Journals: Articles
  • The effectiveness of IVF in unexplained infertility: a systematic Cochrane review

    Pandian, Z., Bhattacharya, S., Nikolaou, D., Vale, L. D., Templeton, A. A.
    Human Reproduction, vol. 18, no. 10, pp. 2001-2007
    Contributions to Journals: Articles
  • More units dedicated to women presenting with miscarriage are needed

    Logan, S., Browne, J., Bhattacharya, S.
    British Medical Journal, vol. 324, no. 7352, pp. 1526
    Contributions to Journals: Letters
  • Current management of ovarian hyperstimulation syndrome

    Shanbhag, S., Bhattacharya, S.
    Hospital Medicine, vol. 63, no. 9, pp. 528-32
    Contributions to Journals: Articles
  • Review of unexplained infertility and obstetric outcome: a 10 year review

    Pandian, Z., Bhattacharya, S., Templeton, A. A.
    Human Reproduction, vol. 16, no. 12, pp. 2593-2597
    Contributions to Journals: Articles
  • Conventional insemination versus intracytoplasmic sperm injection [5] (multiple letters)

    Tucker, M., Graham, J., Han, T., Stillman, R., Levy, M., Bhattacharya, S., Hamilton, M.
    Lancet, vol. 358, no. 9293, pp. 1645-1646
    Contributions to Journals: Letters
  • Fetal antecedents of male factor sub-fertility: how important is birthweight?

    Ozturk, O., Armstrong, K., Bhattacharya, S., Templeton, A. A.
    Human Reproduction, vol. 16, no. 10, pp. 2238-2241
    Contributions to Journals: Articles
  • Conventional in-vitro fertilisation versus intracytoplasmic sperm injection for the treatment of non-male-factor infertility: a randomised controlled trial

    Bhattacharya, S., Hamilton, M., Shaaban, M., Khalaf, Y., Seddler, M., Ghobara, T., Braude, P., Kennedy, R., Rutherford, A., Hartshorne, G., Templeton, A. A.
    The Lancet, vol. 357, no. 9274, pp. 2075-2079
    Contributions to Journals: Articles
  • Should ICSI be the treatment for all cases of in-vitro conception? (multiple letters)

    Hamilton, M., Bhattacharya, S.
    Human Reproduction, vol. 16, no. 4, pp. 801-802
    Contributions to Journals: Letters
  • Avoiding multiple pregnancies in ART: evaluation and implementation of new strategies

    Ozturk, O., Bhattacharya, S., Templeton, A. A.
    Human Reproduction, vol. 16, no. 7, pp. 1319-1321
    Contributions to Journals: Articles
  • A randomised controlled trial of intravenous versus inhalational analgesia during outpatient oocyte recovery

    Thompson, N., Murray, S., MacLennan, F., Ross, J. A. S., Tunstall, M. E., Hamilton, M., Bhattacharya, S.
    Anaesthesia, vol. 55, no. 8, pp. 770-773
    Contributions to Journals: Articles
  • In treating infertility, are multiple pregnancies unavoidable?

    Bhattacharya, S., Templeton, A.
    The New England Journal of Medicine, vol. 343, pp. 58-60
    Contributions to Journals: Editorials
  • Cost-effective treatment of couples with subfertility

    Bhattacharya, S., Hall, M.
    Lancet, vol. 355, no. 9197, pp. 2
    Contributions to Journals: Comments and Debates
  • A randomised trial of endometrial ablation versus hysterectomy for the treatment of dysfunctional uterine bleeding: outcome at four years

    Grant, A., Bhattacharya, S., Mollison, J., McIntosh, E., Abramovich, D. R., Alexander, D. A., Buckingham, K., Cunningham, S., Kitchener, H. C., Parkin, D. E., Pinion, S. B., Atherton-Naji, A., Russell, I. T., Cameron, I., Aberdeen Endometrial Ablation Trials Group
    British Journal of Obstetrics and Gynaecology, vol. 106, pp. 360-366
    Contributions to Journals: Articles
  • Evidence based management of infertility

    Bhattacharya, S.
    BMUS Bulletin, vol. 7, no. Bulletin, pp. 28-32
    Contributions to Journals: Articles
  • Admission-discharge policies for hysteroscopic surgery: a randomised comparison of same day with in-patient admission

    Bhattacharya, S., Cameron, I., Mollison, J. A., Parkin, D., Abramovich, D., Kitchener, H.
    European Journal of Obstetrics & Gynecology and Reproductive Biology, vol. 76, no. 1, pp. 81-84
    Contributions to Journals: Articles
  • A pragmatic randomised comparison of transcervical resection of the endometrium versus endometrial laser ablation for the treatment of menorrhagia

    Bhattacharya, S., Cameron, I. M., Parkin, D., Abramovich, D., Mollison, J. A., Pinion, S., Alexander, D., Grant, A. M., Kitchener, H.
    British Journal of Obstetrics and Gynaecology, vol. 104, no. 5, pp. 601-607
    Contributions to Journals: Articles
  • Factors affecting the outcome of in-vitro fertilisation treatment

    Bhattacharya, S., Templeton, A.
    British Journal of Hospital Medicine, vol. 58, no. 6, pp. 265-267
    Contributions to Journals: Articles
  • Factors affecting the outcome of in-vitro fertilization treatment

    Bhattacharya, S., Templeton, A.
    British Journal of Hospital Medicine, vol. 58, no. 6, pp. 265-267
    Contributions to Journals: Articles
  • How effective is patient controlled analgesia? A randomised comparison of two protocols for pain relief during oocyte recovery

    Bhattacharya, S., Knox, F., Hamilton, M., Templeton, A.
    Human Reproduction, vol. 12, no. 7, pp. 1440-1442
    Contributions to Journals: Articles
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