Optimising the responsible use of antibiotics

Optimising the responsible use of antibiotics

PhD Project 

Antibiotic stewardship has been defined in a consensus statement as “coordinated interventions designed to improve and measure the appropriate use of [antibiotic] agents by promoting the selection of the optimal [antibiotic] drug regimen including dosing, duration of therapy, and route of administration”

The potential benefits of antibiotic stewardship programme (ASP) include improved patient outcomes, reduced adverse events including Clostridium difficile infection (CDI), optimization of resource utilization across the continuum of care.

This research aims to accelerate the improvement of evaluation of Stewardship interventions by tracking core outcomes that closely measure the impact of interventions.

Multiple factors drive the selection of these program interventions and associated target outcomes. Before designing the approach to evaluate an intervention, it is critical to identify the outcomes of interest.

Research plan includes conducting Literature review and determining outcomes of ASP, developing a core outcome set using Delphi method and designing an intervention incorporating established COS.

Supervision: Prof C Ramsay, Dr E Duncan, Dr Magdalena Rzewuska