The HCA programme focuses on the rigorous evaluation of health care interventions.

The underlying philosophy of the programme is the generation of new knowledge through the application of, and interaction between, knowledge synthesis and primary research (particularly randomised controlled trials - RCTs).  The programme is supported by cross cutting methodological research and knowledge synthesis.

Current Project Highlights

  • C-GALL - A randomised controlled trial comparing the clinical effectiveness and cost-effectiveness of laparoscopic cholecystectomy compared with observation/conservative management for preventing recurrent symptoms and complications in adults with uncomplicated symptomatic gallstones
  • DIAMOND: Deep infiltrating endometriosis: management by medical treatment versus early surgery
  • I-TRAC - In-home Tracking of glaucoma: Reliability, Acceptability, and Cost: the I-TRAC Study
  • PURE - The clinical and cost effectiveness of surgical interventions for stones in the lower calyx of the kidney: The PUrE RCT- Percutaneous Nephrolithotomy (PNL), Flexible Ureterorenoscopy (FURS) and Extracorporeal Lithotripsy (ESWL) for lower pole Calyceal Kidney Stones
  • REGAL: Recurrence of Endometriosis: A randomised controlled trial of clinical and cost-effectiveness of Gonadotrophin Releasing Hormone Analogues with add-back hormone replacement therapy versus repeat Laparoscopic surgery
  • SCRIPT: Selective Caries Removal in Posterior Teeth

Completed Project Highlights

  • EDNA - Early Detection of Neovascular Age-related macular degeneration 
  • EuroFIT - Social innovation to improve physical activity and sedentary behaviour through elite European football 
  • PRioRITY II: Prioritising Retention in Randomised Trials
  • InSTAR - Inhaled Steroids in ARDS (Pump Priming Work)
  • RAACENO - Reducing Asthma Attacks in Children using Exhaled Nitric Oxide as a biomarker to inform treatment strategy - a randomised trial 
  • TestES Consortium
  • THISTLE - Improving intrapartum outcomes for mothers and babies in Scotland: a stepped-wedge RCT of an intrapartum emergencies training package in 15 Scottish maternity units