Professor David St Clair

Professor David St Clair

Chair in Applied Medicine

Overview

Contact Details

Research

Research Overview

Psychiatric Genetics, particularly of schizophrenia.

Publications

Publications 

Currently viewing:
Filter by Publication Type

Page 1 of 8 Results 1 to 25 of 190

  • Genome-wide association study identifies 30 loci associated with bipolar disorder

    Stahl, E. A., Breen, G., Forstner, A. J., McQuillin, A., Ripke, S., Trubetskoy, V., Mattheisen, M., Wang, Y., Coleman, J. R., Gaspar, H. A., de Leeuw, C. A., Steinberg, S., Pavlides, J. M., Trzaskowski, M., Byrne, E. M., Pers, T. H., Holmans, P. A., Richards, A. L., Abbott, L., Agerbo, E., Akil, H., Albani, D., Alliey-Rodriguez, N., Als, T. D., Anjorin, A., Antilla, V., Awasthi, S., Badner, J. A., Bækvad-Hansen, M., Barchas, J. D., Bass, N., Bauer, M., Belliveau, R., Bergen, S. E., Pedersen, C. B., Bøen, E., Boks, M. P., Boocock, J., Budde, M., Bunney, W., Burmeister, M., Bybjerg-Grauholm, J., Byerley, W., Casas, M., Cerrato, F., Cervantes, P., Chambert, K., Charney, A. W., Chen, D., St Clair, D., eQTLGen Consortium, BIOS Consortium, the Bipolar Disorder Working Group of the Psychiatric Genomics Consortium

    Nature Genetics, vol. 51, pp. 793-803

    Contributions to Journals: Articles

  • Consensus paper of the WFSBP Task Force on Genetics: Genetics, epigenetics and gene expression markers of major depressive disorder and antidepressant response

    Fabbri, C., Hosak, L., Mössner, R., Giegling, I., Mandelli, L., Bellivier, F., Claes, S., Collier, D. A., Corrales, A., Delisi, L. E., Gallo, C., Gill, M., Kennedy, J. L., Leboyer, M., Lisoway, A., Maier, W., Marquez, M., Massat, I., Mors, O., Muglia, P., Nöthen, M. M., O’Donovan, M. C., Ospina-Duque, J., Propping, P., Shi, Y., St Clair, D., Thibaut, F., Cichon, S., Mendlewicz, J., Rujescu, D., Serretti, A.

    World Journal of Biological Psychiatry, vol. 18, no. 1, pp. 5-28

    Contributions to Journals: Review articles

  • Genetics of schizophrenia: A consensus paper of the WFSBP Task Force on Genetics

    Giegling, I., Hosak, L., Mössner, R., Serretti, A., Bellivier, F., Claes, S., Collier, D. A., Corrales, A., DeLisi, L. E., Gallo, C., Gill, M., Kennedy, J. L., Leboyer, M., Maier, W., Marquez, M., Massat, I., Mors, O., Muglia, P., Nöthen, M. M., Ospina-Duque, J., Owen, M. J., Propping, P., Shi, Y. Y., St Clair, D., Thibaut, F., Cichon, S., Mendlewicz, J., O'Donovan, M. C., Rujescu, D.

    World Journal of Biological Psychiatry, vol. 18, no. 7, pp. 492-505

    Contributions to Journals: Articles

  • An integrated genetic-epigenetic analysis of schizophrenia: Evidence for co-localization of genetic associations and differential DNA methylation

    Hannon, E., Dempster, E., Viana, J., Burrage, J., Smith, A. R., Macdonald, R., St Clair, D., Mustard, C., Breen, G., Therman, S., Kaprio, J., Toulopoulou, T., Pol, H. E., Bohlken, M. M., Kahn, R. S., Nenadic, I., Hultman, C. M., Murray, R. M., Collier, D. A., Bass, N., Gurling, H., McQuillin, A., Schalkwyk, L., Mill, J.

    Genome Biology, vol. 17, 176

    Contributions to Journals: Articles

  • Balanced translocation linked to psychiatric disorder, glutamate, and cortical structure/function

    Thomson, P. A., Duff, B., Blackwood, D. H., Romaniuk, L., Watson, A., Whalley, H. C., Li, X., Dauvermann, M. R., Moorhead, T. W. J., Bois, C., Ryan, N. M., Redpath, H., Hall, L., Morris, S. W., Van Beek, E. J., Roberts, N., Porteous, D. J., St Clair, D., Whitcher, B., Dunlop, J., Brandon, N. J., Hughes, Z. A., Hall, J., McIntosh, A., Lawrie, S. M.

    npj Schizophrenia, vol. 2, 16024

    Contributions to Journals: Articles

  • Rare loss-of-function variants in SETD1A are associated with schizophrenia and developmental disorders

    Singh, T., Kurki, M. I., Curtis, D., Purcell, S. M., Crooks, L., McRae, J., Suvisaari, J., Chheda, H., Blackwood, D., Breen, G., Pietilinen, O., Gerety, S. S., Ayub, M., Blyth, M., Cole, T., Collier, D., Coomber, E. L., Craddock, N., Daly, M. J., Danesh, J., DiForti, M., Foster, A., Freimer, N. B., Geschwind, D., Johnstone, M., Joss, S., Kirov, G., Körkkö, J., Kuismin, O., Holmans, P., Hultman, C. M., Iyegbe, C., Lönnqvist, J., Mnnikkö, M., McCarroll, S. A., McGuffin, P., McIntosh, A. M., McQuillin, A., Moilanen, J. S., Moore, C., Murray, R. M., Newbury-Ecob, R., Ouwehand, W., Paunio, T., Prigmore, E., Rees, E., Roberts, D., Sambrook, J., Sklar, P., St Clair, D., Veijola, J., Walters, J. T., Williams, H., Sullivan, P. F., Hurles, M. E., O'Donovan, M. C., Palotie, A., Owen, M. J., Barrett, J. C.

    Nature Neuroscience, vol. 19, no. 4, pp. 571-577

    Contributions to Journals: Articles

  • Genetic influences on schizophrenia and subcortical brain volumes: large-scale proof of concept

    Franke, B., Stein, J. L., Ripke, S., Anttila, V., Hibar, D. P., van Hulzen, K. J. E., Arias-Vasquez, A., Smoller, J. W., Nichols, T. E., Neale, M. C., McIntosh, A. M., Lee, P., McMahon, F. J., Meyer-Lindenberg, A., Mattheisen, M., Andreassen, O. A., Gruber, O., Sachdev, P. S., Roiz-Santianez, R., Saykin, A. J., Ehrlich, S., Mather, K. A., Turner, J. A., Wright, M. J., O'Donovan, M. C., Thompson, P. M., Neale, B. M., Medland, S. E., Sullivan, P. F., Psychiat Genomics Consortium, ENIGMA Consortium, St Clair, D. M., Pike, G. B.

    Nature Neuroscience, vol. 19, no. 3, pp. 420-431

    Contributions to Journals: Articles

  • Expression analysis in a rat psychosis model identifies novel candidate genes validated in a large case-control sample of schizophrenia

    Ingason, A., Giegling, I., Hartmann, A. M., Genius, J., Konte, B., Friedl, M., Ripke, S., Sullivan, P. F., St Clair, D., Collier, D. A., O'Donovan, M. C., Mirnics, K., Rujescu, D.

    Translational Psychiatry, vol. 5, e656

    Contributions to Journals: Articles

  • Bridging the translational divide: Identical cognitive touchscreen testing in mice and humans carrying mutations in a disease-relevant homologous gene

    Nithianantharajah, J., McKechanie, A. G., Stewart, T. J., Johnstone, M., Blackwood, D. H., St Clair, D., Grant, S. G., Bussey, T. J., Saksida, L. M.

    Scientific Reports, vol. 5, 14613

    Contributions to Journals: Articles

  • The UK10K project identifies rare variants in health and disease

    Walter, K., Min, J. L., Huang, J., Crooks, L., Memari, Y., McCarthy, S., Perry, J. R., Xu, C., Futema, M., Lawson, D., Iotchkova, V., Schiffels, S., Hendricks, A. E., Danecek, P., Li, R., Floyd, J., Wain, L. V., Barroso, I., Humphries, S. E., Hurles, M. E., Zeggini, E., Barrett, J. C., Plagnol, V., Richards, J. B., Greenwood, C. M., Timpson, N. J., Durbin, R., Bala, S., Clapham, P., Coates, G., Cox, T., Daly, A., Du, Y., Edkins, S., Ellis, P., Flicek, P., Guo, X., Guo, X., Huang, L., Jackson, D. K., Joyce, C., Keane, T., Kolb-Kokocinski, A., Langford, C., Li, Y., Liang, J., Lin, H., Liu, R., Breen, G., St Clair, D., UK10K Consortium

    Nature, vol. 526, no. 7571, pp. 82-89

    Contributions to Journals: Articles

  • Copy Number Variations in DISC1 and DISC1-Interacting Partners in Major Mental Illness

    Johnstone, M., Maclean, A., Heyrman, L., Lenaerts, A., Nordin, A., Nilsson, L., De Rijk, P., Goossens, D., Adolfsson, R., St Clair, D. M., Hall, J., Lawrie, S. M., McIntosh, A. M., Del-Favero, J., Blackwood, D. H. R., Pickard, B. S.

    Journal of Neuropsychiatry and Clinical Neurosciences, vol. 1, no. 3, pp. 175-190

    Contributions to Journals: Articles

  • Prenatal Nutritional Deficiency Reprogrammed Postnatal Gene Expression in Mammal Brains: Implications for Schizophrenia

    Xu, J., He, G., Zhu, J., Zhou, X., Clair, D. S., Wang, T., Xiang, Y., Zhao, Q., Xing, Q., Liu, Y., Wang, L., Li, Q., He, L., Zhao, X.

    International Journal of Neuropsychopharmacology, vol. 18, no. 4, pyu054

    Contributions to Journals: Articles

  • No Association Between NRG1 and ErbB4 Genes and Psychopathological Symptoms of Schizophrenia

    Tosato, S., Zanoni, M., Bonetto, C., Tozzi, F., Francks, C., Ira, E., Tomassi, S., Bertani, M., Rujescu, D., Giegling, I., St Clair, D., Tansella, M., Ruggeri, M., Muglia, P.

    NeuroMolecular Medicine, vol. 16, no. 4, pp. 742-751

    Contributions to Journals: Articles

  • Common genetic variants on 1p13.2 associate with risk of autism

    Xia, K., Guo, H., Xun, G., Zuo, L., Peng, Y., He, Y., Xiong, Z., Sun, L., Pan, Q., Long, Z., Zou, X., Lu, L., Liu, Y., Tian, D., Long, L., Liu, Y., Peng, H., Luo, X., Su, W., Liang, D., Dai, H., Yan, X., Feng, Y., Tang, B., Miedzybrodzka, Z., Xia, J., Zhang, Z., Luo, X., Zhang, X., St Clair, D., Zhao, J., Zhang, F.

    Molecular Psychiatry, vol. 19, no. 11, pp. 1212-1219

    Contributions to Journals: Articles

  • Biological insights from 108 schizophrenia-associated genetic loci

    Ripke, S., Neale, B. M., Corvin, A., Walters, J. T., Farh, K. H., Holmans, P. A., Lee, P., Bulik-Sullivan, B., Collier, D. A., Huang, H., Pers, T. H., Agartz, I., Agerbo, E., Albus, M., Alexander, M., Amin, F., Bacanu, S. A., Begemann, M., Belliveau, R. A., Bene, J., Bergen, S. E., Bevilacqua, E., Bigdeli, T. B., Black, D. W., Bruggeman, R., Buccola, N. G., Buckner, R. L., Byerley, W., Cahn, W., Cai, G., Campion, D., Cantor, R. M., Carr, V. J., Carrera, N., Catts, S. V., Chambert, K. D., Chan, R. C., Chen, R. Y., Chen, E. Y., Cheng, W., Cheung, E. F., Chong, S. A., Cloninger, C. R., Cohen, D., Cohen, N., Cormican, P., Craddock, N., Crowley, J. J., Curtis, D., St Clair, D., Schizophrenia Working Group of the Psychiatric Genomics Consortium

    Nature, vol. 511, no. 7510, pp. 421-427

    Contributions to Journals: Articles

  • Modeling a genetic risk for schizophrenia in iPSCs and Mice reveals neural stem cell deficits associated with adherens junctions and polarity

    Yoon, K. J., Nguyen, H. N., Ursini, G., Zhang, F., Kim, N. S., Wen, Z., Makri, G., Nauen, D., Shin, J. H., Park, Y., Chung, R., Pekle, E., Zhang, C., Towe, M., Hussaini, S. M. Q., Lee, Y., Rujescu, D., St. Clair, D., Kleinman, J. E., Hyde, T. M., Krauss, G., Christian, K. M., Rapoport, J. L., Weinberger, D. R., Song, H., Ming, G. L.

    Cell Stem Cell, vol. 15, no. 1, pp. 79-91

    Contributions to Journals: Articles

  • An inherited duplication at the gene p21 protein-activated Kinase 7 (PAK7) is a risk factor for psychosis

    Morris, D. W., Pearson, R. D., Cormican, P., Kenny, E. M., O'Dushlaine, C. T., Perreault, L. P. L., Giannoulatou, E., Tropea, D., Maher, B. S., Wormley, B., Kelleher, E., Fahey, C., Molinos, I., Bellini, S., Pirinen, M., Strange, A., Freeman, C., Thiselton, D. L., Elves, R. L., Regan, R., Ennis, S., Dinan, T. G., McDonald, C., Murphy, K. C., O'Callaghan, E., Waddington, J. L., Walsh, D., O'Donovan, M., Grozeva, D., Craddock, N., Stone, J., Scolnick, E., Purcell, S., Sklar, P., Coe, B., Eichler, E. E., Ophoff, R., Buizer, J., Szatkiewicz, J., Hultman, C., Sullivan, P., Gurling, H., Mcquillin, A., St Clair, D., Rees, E., Kirov, G., Walters, J., Blackwood, D., Johnstone, M., Donohoe, G., The International Schizophrenia Consortium (ISC), SGENE+ Consortium, O'Neill, F. A., The Wellcome Trust Case Control Consortium 2 (WTCCC2), Kendler, K. S., Gill, M., Riley, B. P., Spencer, C. C. A., Corvin, A.

    Human Molecular Genetics, vol. 23, no. 12, pp. 3316-3326

    Contributions to Journals: Articles

  • Recurrent deletions of ULK4 in schizophrenia: a gene crucial for neuritogenesis and neuronal motility

    Lang, B., Pu, J., Hunter, I., Liu, M., Martin-Granados, C., Reilly, T. J., Gao, G., Guan, Z., Li, W., Shi, Y., He, G., He, L., Stefansson, H., St Clair, D., Blackwood, D. H., McCaig, C. D., Shen, S.

    Journal of Cell Science, vol. 127, no. 3, pp. 630-640

    Contributions to Journals: Articles

Show 10 | 25 | 50 | 100 results per page