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The Institute of Applied Health Sciences

Professor Sam Philip

Professor Sam Philip
Professor Sam Philip
Professor Sam Philip

MBBS, MD (Univ Kerala), FRCP (Edinburgh), MD (Univ Aberdeen)

Honorary Professor

About
Email Address
s.philip@abdn.ac.uk
Office Address

Grampian Diabetes Research unit, JJR Macleod Centre for Diabetes, Endocrinology and Metabolism, David Anderson Building Aberdeen AB25 2ZP

School/Department
School of Medicine, Medical Sciences and Nutrition
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Biography

He is currently in NHS Grampian as a Consultant Physician in the Department of Diabetes and Endocrinology and as an honorary Professor at the University of Aberdeen. 

Prof Sam Philip graduated from the Mahatma Gandhi University (India). He obtained his postgraduate degree in General (Internal) Medicine from Trivandrum Medical college (M Sivaraman Nair Gold Medal in 1999). Having obtained his MRCP(UK) from the Royal College of Physicians Edinburgh, he started his specialisation in Diabetes and Endocrinology at Aberdeen Royal Infirmary in 2001.

He is the national clinical lead for SCI-Diabetes Scotland national diabetes management system.  He is the clinical lead (North) for Scottish health research register (SHARE) and the Grampian Diabetes Research Unit.

He was clinical research fellow in Biomedical Physics on automated retinopathy detection as part of the 'Ophthalmic Imaging Group' led by Dr John Olson and Prof Peter Sharp and obtained an MD from the University of Aberdeen. He won the Diabetes UK Young Diabetologist Award  2006 and Fould’s trophy (annual congress of the Royal College of Ophthalmologists 2005) for his work.

His clinical interests include insulin pump therapy and is the lead for the adult insulin pump service in Grampian.  He is leading the development of teleconsultation service for diabetes in Orkney and Shetland and use of technology for supporting diabetes care in the isles. He has a strong interest in research with clinical application and has won awards for projects on automated retinopathy detection, integrated screening (National Diabetes MCN Professional conference 2007), inpatient diabetes hypoglycaemia management (Diabetes in Scotland conference 2006, 2010), telemedicine consultation (RSM ehealth conference 2010), hybrid education models for technology.

He was the Training programme director for Diabetes and Endocrinology (North 2014 to 2021).He was the chair of the Scottish Study group for young people with diabetes (2021-2023)

Research

Research Overview

Diabetic Retinopathy, Medical Imaging, Telemedicine, Automation  and use of  information technology in health care.

Research Areas

Applied Health Sciences

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Computing Science

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Biomedical Sciences

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Research Specialisms

  • Diagnostic Imaging
  • Databases
  • Health Informatics
  • Endocrinology
  • Diabetes

Our research specialisms are based on the Higher Education Classification of Subjects (HECoS) which is HESA open data, published under the Creative Commons Attribution 4.0 International licence.

Current Research

Diabetic retinopathy, Diabetes Telemedicine, Diabetes epidemiology, Information technology for Diabetes care,Functional MRI

Collaborations

Scottish Health Research Register 

Curator : Scottish Diabetes Register for  Young people with Diabetes

Funding and Grants

Research Activity

Academic

Principal investigator Can automated analysis of sequential retinal images of people attending diabetic retinopathy screening predict future referral to Ophthalmology? Funded by Chief Scientist Office, Scotland (£224,520) Dec
2012 to Nov 2015

Co-investigator Patterns of weight changes after diagnosis in patients with Type 2 Diabetes and their relationship with metabolic and cardiovascular outcomes. Funded by chief scientist office (£50,000) June 2012 May 2013

Co-investigator The Relationship between Diabetes and Stroke in an NHS Grampian Stroke Population June 2012 May 2013, NHS Grampian Endowments 3,000 Co -Investigator

Co-investigator CZG/2/536 - The value of automated grading of retinopathy to predict 5-year cardiovascular disease risk in people with diabetes in Scotland Funded by chief scientist office

Co-investigator in a (NHS Health Technology Assessment Programme) Improving the value of screening for diabetic macular oedema using surrogate photographic markers (Project No 06/402/49, January 2008- January 2010, £464,949).

Co-investigator in a Chief Scientist Office funded study- ‘The Role of Automated Level-Two Grading within The Diabetic Retinopathy Screening  Collaborative Network’ (CZH/4/316) £183743. A multi-centre study involving NHS Grampian, NHS Tayside, NHS Lothian, NHS Lanarkshire, NHS Greater Glasgow.

Co-investigator:   Muscle fat compartments and turnover as a determinant of insulin sensitivity: D Dawson (Chief Investigator), M Delibegovic, S Gray, S Philip, P Whitfield, F Thies, G Lobley, British Heart Foundation Project Grant no. PG/15/88/31780, £259,358, 2016-2019

 

Academic trials hosted

Local Principal investigator: Lowering Events in Non-proliferative Retinopathy in Scotland (LENS) NCT03439345

Local Principal investigator: Continuous Glucose Monitoring in Women with Type 1 Diabetes in Pregnancy Trial. UKCRN ID 12637, funded by Juvenile Diabetes Research Foundation Limited (JDRF) Diabetes Research & Wellness Foundation (DRWF) 

Local Principal investigator: Genetics of Diabetes Audit and Research in Tayside and Scotland. NCT02712632 Scottish Diabetes Research Network

Local Principal investigator: REducing With MetfOrmin Vascular Adverse Lesions in Type 1 Diabetes (REMOVAL) NCT01483560 Juvenile Diabetes Research Foundation.

 

Commercial

Principal investigator: A Heart Disease Study of Semaglutide in Patients With Type 2 Diabetes (SOUL) Expected date of closing 2024

Principal investigator: A Research Study to See How Semaglutide Works Compared to Placebo in People with Type 2 Diabetes and Chronic Kidney Disease (FLOW) Expected date of closing 2023

Principal investigator: Effect of Albiglutide, When Added to Standard Blood Glucose Lowering Therapies, on Major Cardiovascular Events in Subjects With Type 2 Diabetes Mellitus: (Harmony) Expected date of closed 2020

Principal investigator: SAGE-Observational study of glycaemic control & QoL in Type 1 diabetes. Sponsor: Sanofi closed 2019

Principal investigator: Exenatide Study of Cardiovascular Event Lowering Trial (EXSCEL): A Trial To Evaluate Cardiovascular Outcomes After Treatment With Exenatide Once Weekly In Patients With Type 2 Diabetes Mellitus NCT01144338, Sponsor: Amylin Pharmaceuticals, LLC.

Principal investigator:A European, Prospective, Controlled, Non-Interventional, Stratified Cluster Randomised Study to Assess the Frequency of Self-Monitoring of Blood Glucose, Quality of Life, and Patient-Reported Outcomes in Subjects with type I or type II Diabetes being Treated with Insulin. Study Number: RD001073 Sponsor Roche Pharmaceuticals

Co-investigator: Liraglutide Effect and Action in Diabetes: Evaluation of
Cardiovascular Outcome Results - A Long Term Evaluation (LEADER®). NCT01179048 Sponsor Novo Nordisk. 

Co-investigator: TECOS: A Randomized, Placebo Controlled Clinical Trial to Evaluate Cardiovascular Outcomes After Treatment With Sitagliptin in Patients With Type 2 Diabetes Mellitus and Inadequate Glycemic Control NCT00790205. Sponsor:Merck 

 

Teaching

Teaching Responsibilities

2008:  Supervisor for Medical student electives/ Intercalation ( BSc (Hons) in Medical Sciences)

2008:  Supporting Diabetes and Endocrinology undergraduate curriculum

2008: Supporting allied professional and postgraduate education

2008- present: Educational supervision of Registrars/ Specialty trainees 

2014 -2021 :Regional Training Programme Director for Diabetes and Endocrinology (North)

2015 -2018: National training programme director for Diabetes and Endocrinology (Scotland)

2008- 2014: Educational supervision of Foundation trainees 

 

Publications

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  • Risk of cardiovascular disease and total mortality in adults with type 1 diabetes: Scottish registry linkage study

    Livingstone, S. J., Looker, H. C., Hothersall, E. J., Wild, S. H., Lindsay, R. S., Chalmers, J., Cleland, S., Leese, G. P., McKnight, J., Morris, A. D., Pearson, D. W. M., Peden, N. R., Petrie, J. R., Philip, S., Sattar, N., Sullivan, F., Colhoun, H. M.
    PLoS Medicine, vol. 9, no. 10, e1001321
    Contributions to Journals: Articles

  • Automated clarity assessment of retinal images using regionally based structural and statistical measures

    Fleming, A. D., Philip, S., Goatman, K. A., Sharp, P. F., Olson, J. A.
    Medical Engineering & Physics, vol. 34, no. 7, pp. 849-859
    Contributions to Journals: Articles

  • Diabetic retinopathy at diagnosis of type 2 diabetes in Scotland

    Looker, H. C., Nyangoma, S. O., Cromie, D., Olson, J. A., Leese, G. P., Black, M., Doig, J., Lee, N., Lindsay, R. S., McKnight, J. A., Morris, A. D., Philip, S., Sattar, N., Wild, S. H., Colhoun, H. M., Scottish Diabetic Retinopathy Screening Collaborative
    Diabetologia, vol. 55, no. 9, pp. 2335-2342
    Contributions to Journals: Articles

  • External quality assurance for image grading in the Scottish Diabetic Retinopathy Screening Programme

    Goatman, K. A., Philip, S., Fleming, A. D., Harvey, R. D., Swa, K. K., Styles, C., Black, M., Sell, G., Lee, N., Sharp, P. F., Olson, J. A.
    Diabetic Medicine, vol. 29, no. 6, pp. 776-783
    Contributions to Journals: Articles

  • Response to ‘Improved Automated Screening of Diabetic Retinopathy’ by Carlos M. Oliveira et al.

    Fleming, A. D., Olson, J. A., Sharp, P. F., Goatman, K. A., Philip, S.
    Ophthalmologica, vol. 227, no. 3, pp. 173; author reply 174
    Contributions to Journals: Letters

  • Do men develop type 2 diabetes at lower body mass indices than women?

    Logue, J., Walker, J. J., Colhoun, H. M., Leese, G. P., Lindsay, R. S., McKnight, J. A., Morris, A. D., Pearson, D. W., Petrie, J. R., Philip, S., Wild, S. H., Sattar, N., Scottish Diabetes Research Network (SDRN) Epidemiology group
    Diabetologia, vol. 54, no. 12, pp. 3003-3006
    Contributions to Journals: Articles

  • Prospective observational study of referrals to hospital diabetes specialist care team (2004-2008) at a tertiary care centre

    Muller, K., Ghouri, N., Walker, L., Philip, S.
    British Journal of Diabetes and Vascular Disease, vol. 11, no. 6, pp. 298-303
    Contributions to Journals: Articles

  • The evidence for automated grading in diabetic retinopathy screening

    Fleming, A. D., Philip, S., Goatman, K. A., Prescott, G. J., Sharp, P. F., Olson, J. A.
    Current Diabetes Reviews, vol. 7, no. 4, pp. 246-252
    Contributions to Journals: Articles

  • Effect of socioeconomic status on mortality among people with type 2 diabetes: a study from the Scottish Diabetes Research Network Epidemiology Group

    Walker, J. J., Livingstone, S. J., Colhoun, H. M., Lindsay, R. S., Mcknight, J. A., Morris, A. D., Petrie, J. R., Philip, S., Sattar, N., Wild, S. H., Scottish Diabet Res Network
    Diabetes Care, vol. 34, no. 5, pp. 1127-1132
    Contributions to Journals: Articles

  • Detection of new vessels on the optic disc using retinal photographs

    Goatman, K. A., Fleming, A. D., Philip, S., Williams, G. J., Olson, J. A., Sharp, P. F.
    IEEE Transactions on Medical Imaging, vol. 30, no. 4, pp. 972-979
    Contributions to Journals: Articles

  • Achieved levels of HbA1c and likelihood of hospital admission in people with type 1 diabetes in the Scottish population: a study from the Scottish Diabetes Research Network Epidemiology Group

    Govan, L., Wu, O., Briggs, A., Colhoun, H. M., Fischbacher, C. M., Leese, G. P., McKnight, J. A., Philip, S., Sattar, N., Wild, S. H., Lindsay, R. S., Scottish Diabetes Research Network (SDRN) Epidemiology group
    Diabetes Care, vol. 34, no. 9, pp. 1992-1997
    Contributions to Journals: Articles

  • Diabetes mellitus and other metabolic disorders

    Currie, G. P., Douglas, G., Cactus, C., Philip, S.
    The Flesh and Bones of Medicine. Currie, G. (ed.). Mosby/Elsevier,, pp. 194-208, 15 pages
    Chapters in Books, Reports and Conference Proceedings: Chapters

  • Newer agents for blood glucose control in type 2 diabetes: systematic review and economic evaluation

    Waugh, N. R., Cummins, E., Royle, P. L., Clar, C., Marien, M., Richter, B., Philip, S.
    Health Technology Assessment, vol. 14, no. 36, pp. 1-248
    Contributions to Journals: Articles

  • The role of haemorrhage and exudate detection in automated grading of diabetic retinopathy

    Fleming, A. D., Goatman, K. A., Philip, S., Williams, G. J., Prescott, G. J., Scotland, G. S., McNamee, P., Leese, G. P., Wykes, W. N., Sharp, P. F., Olson, J. A., Scottish Diabetic Retinopathy Clinical Research Network
    British Journal of Ophthalmology, vol. 94, no. 6, pp. 706-711
    Contributions to Journals: Articles

  • Radioiodine therapy (RAI) for Graves' disease (GD) and the effect on ophthalmopathy: a systematic review

    Acharya, S. H., Avenell, A., Philip, S., Burr, J., Bevan, J. S., Abraham, P.
    Clinical Endocrinology, vol. 69, no. 6, pp. 943-950
    Contributions to Journals: Articles

  • Evaluation of a system for automatic detection of diabetic retinopathy from color fundus photographs in a large population of patients with diabetes: Response to Abramhoff et al

    Olson, J. A., Sharp, P. F., Fleming, A., Philip, S., Philip, S.
    Diabetes Care, vol. 31, no. 8, pp. e63; author reply e64
    Contributions to Journals: Letters

  • Glycaemic control and body mass index in late-adolescents and young adults with type 1 diabetes mellitus: a population-based study

    Acharya, S. H., Philip, S., Viswanath, A. K., Boroujerdi, M., Waugh, N. R., Pearson, D. W. M.
    Diabetic Medicine, vol. 25, no. 3, pp. 360-364
    Contributions to Journals: Articles

  • Cost-effectiveness of implementing automated grading within the national screening programme for diabetic retinopathy in Scotland

    Scotland, G. S., McNamee, P., Philip, S., Fleming, A. D., Goatman, K. A., Prescott, G. J., Fonseca, S., Sharp, P. F., Olson, J. A.
    British Journal of Ophthalmology, vol. 91, no. 11, pp. 1518-1523
    Contributions to Journals: Articles

  • The efficacy of “disease/no disease” grading for diabetic retinopathy in a systematic screening programme

    Philip, S., Fleming, A. D., Goatman, K. A., Fonseca, S., McNamee, P., Scotland, G. S., Prescott, G. J., Sharp, P. F., Olson, J. A.
    British Journal of Ophthalmology, vol. 91, no. 11, pp. 1512-1517
    Contributions to Journals: Articles

  • Is annual surveillance of all treated hypothyroid patients necessary?

    Viswanath, A. K., Avenell, A., Philip, S., Acharya, S. H., Maclennan, G., Dalziel, K., Pereira, O., Copland, S. A., Bevan, J. S., Abraham, P.
    BMC Endocrine Disorders, vol. 7, 4
    Contributions to Journals: Articles

  • Automatic detection of retinal anatomy to assist diabetic retinopathy screening

    Fleming, A. D., Goatman, K. A., Philip, S., Olson, J. A., Sharp, P. F.
    Physics in Medicine and Biology, vol. 52, no. 2, pp. 331-345
    Contributions to Journals: Articles

  • Diagnosing diabetes mellitus: Contemporary use of the oral glucose tolerance test in a regional diabetes centre

    Viswanath, A. K., Pereira, O., Philip, S., McHardy, K. C.
    Practical Diabetes International, vol. 23, no. 7, pp. 287-290
    Contributions to Journals: Articles

  • Automated image quality assessment is an essential step for automating diabetic retinopathy detection

    Philip, S., Fleming, A. D., Goatman, K. A., Sharp, P. F., Olson, J.
    Diabetes, vol. 55, no. Supplement 1, pp. A513-A513
    Contributions to Journals: Articles

  • Automated assessment of diabetic retinal image quality based on clarity and field definition

    Fleming, A. D., Philip, S., Goatman, K. A., Olson, J. A., Sharp, P. F.
    Investigative Ophthalmology & Visual Science, vol. 47, no. 3, pp. 1120-1125
    Contributions to Journals: Articles

  • Automated microaneurysm detection using local contrast normalization and local vessel detection

    Fleming, A. D., Goatman, K. A., Olson, J. A., Sharp, P. F., Philip, S.
    IEEE Transactions on Medical Imaging, vol. 25, no. 9, pp. 1223-1232
    Contributions to Journals: Articles
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