
MRCP, MSc, MD
Reader (Clinical)
- About
-
Room 1:009, Polwarth Building Division of Applied Health Sciences University of Aberdeen Foresterhill Aberdeen AB25 2ZD
Biography
Carl is a clinical reader and honorary consultant in neurology. He graduated in medicine from Cambridge University in 1988, did his early postgraduate medical training in London, Newcastle and Falkirk and then trained in neurology, stroke and epidemiology in Edinburgh. He spent a year in Melbourne where he specialised in movement disorders before taking up his present post in 2001. He is married to Gay, a GP, and has one daughter, Helena. A committed Christian, he would like to have more time to serve in his church and develop his interests in Fairtrade and conservation.
External Memberships
Cochrane Movement Disorders Group editorial board member
UK Parkinson’s Excellence Network regional lead
Latest Publications
Cognitive and Motor Decline in Dementia with Lewy Bodies and Parkinson's Disease Dementia
Movement Disorders Clinical PracticeContributions to Journals: Articles- [ONLINE] DOI: https://doi.org/10.1002/mdc3.13752
- [ONLINE] View publication in Scopus
The evolution of diagnosis from symptom onset to death in progressive supranuclear palsy (PSP) and corticobasal degeneration (CBD) compared to Parkinson's disease (PD)
Journal of NeurologyContributions to Journals: ArticlesAchieving proportionate governance review in Scotland: Threats and solutions
Journal of the Royal College of Physicians of Edinburgh, vol. 53, no. 1, pp. 74-79Contributions to Journals: Comments and Debates- [ONLINE] DOI: https://doi.org/10.1177/14782715231153033
- [ONLINE] View publication in Scopus
Is the assumption of waning of treatment effect applied consistently across NICE technology appraisals?: A case-study focusing on disease-modifying therapies for treatment of multiple sclerosis
International Journal of Technology Assessment in Health Care, vol. 38, no. 1, pp. e83Contributions to Journals: Review articlesThe incidence, baseline predictors and outcomes of dementia in an incident cohort of Parkinson’s disease and controls
Journal of Neurology, vol. 269, pp. 4288–4298Contributions to Journals: Articles
- Research
-
Research Overview
Carl is a consultant neurologist with subspecialty interest in movement disorders. His main research interests are in evidence-based medicine and broader aspects of clinical epidemiology such as incidence and prognostic studies, particularly in relation to Parkinson's disease, other movement disorders and stroke. His team have established several cohorts of parkinsonian patients for long-term follow-up and support a number of non-industry sponsored clinical trials and Cochrane reviews, whilst also trying to promote multidisciplinary neurology research in Aberdeen.
Research Areas
Accepting PhDs
I am currently accepting PhDs in Nutrition and Health.
Please get in touch if you would like to discuss your research ideas further.
Nutrition and Health
Accepting PhDsResearch Specialisms
- Clinical Medicine
Our research specialisms are based on the Higher Education Classification of Subjects (HECoS) which is HESA open data, published under the Creative Commons Attribution 4.0 International licence.
Current Research
The PINE study: a population-based incidence cohort of people with Parkinson's disease and other parkinsonian disorders, along with their carers and controls who are being followed up lifelong to establish long-term prognosis.
The Parkinson's Incidence Cohorts Collaboration: an individual patient data meta-analysis of all population- based incidence cohorts of Parkinson's disease to assess prognosis and allow prognostic modelling.
The Scottish PSP/CBD prevalence cohort: a cohort of people with two related Parkinson's plus disorders, Progressive Supranuclear Palsy and Corticobasal Degeneration as well as Parkinson's disease controls, to assess diagnostic and care pathways and prognosis.
Past Research
Cochrane systematic reviews of randomised trials in stroke care
Prognostic modelling in acute stroke
Incidence of Parkinson's disease and other parkinsonian disorders in North-East Scotland
Prevalence of multiple sclerosis in North-East Scotland and northern isles
Randomised trial of physiotherapy for cervical dystonia
Knowledge Exchange
Member of Parkinson's Excellence Network
Collaborations
Cochrane Collaboration Stroke Review Group, Professors Charles Warlow and Peter Sandercock, University of Edinburgh, UK, 1993-98.
Scottish Audit of Intracranial Vascular Malformations, Professor Rustam Al-Shahi Salman, University of Edinburgh, UK, 2002-2014.
PDMED trial, Professor Carl Clarke, University of Birmingham, UK, 2004-2020.
Clinical trial methods in neurodegenerative diseases, Professor John Zajicek, University of Plymouth, UK, 2009-2014.
PDCOMM trial, Professor Sackley, University of Nottingham, UK, 2016 ongoing.
NICE technology appraisals for multiple sclerosis, Universities of Warwick and Exeter, UK, 2016 ongoing
Parkinson's Incidence Cohorts Collaboration, Professor Tysnes, Dr Guido Alves, Professor Lars Forsgren, Dr Caroline Williams-Gray, Dr Alison Yarnall, Universities of Stavanger (Norway), Umea (Sweden), Cambridge (UK) and Newcastle (UK), 2018 ongoing
PD Connect exercise trial, Julie Jones, Robert Gordon University, Aberdeen, UK, 2019 ongoing
Supervision
Dr Kate Taylor (MD), 2002-06, Incidence and prognosis of parkinsonism in north-east Scotland: a pilot study.
Clare Harris (MSc), 2006-08, PINE participants attitudes to brain donation.
Dr Robert Caslake (PhD), 2006-11, Incidence and short-term porgnosis of Parkinson's disease andother parkinsonian disorders in north-east Scotland.
Dr Elizabeth Visser (MD), 2009-13, Prevalence of multiple sclerosis in northern Scotland.
Dr David McGhee (PhD), 2009-13, Improving clinical trial design in neurodegenerative diseases.
Dr Angus Macleod (PhD), 2012-15, Predicting mortality and dependency in Parkinson's disease.
Dr Diane Swallow (PhD), 2016-21, Assessing diagnostic pathways in progressive supranuclear palsy and corticobasal degeneration.
Funding and Grants
Research funding has been obtained from:
Parkinson’s UK, Scottish Chief Scientist Office, BMA Doris Hillier award, RS Macdonald Trust, BUPA Foundation, NHS Grampian endowments, Dystonia Society, National Institute for Health Research.
- Teaching
-
Teaching Responsibilities
Lectures and clinical teaching of neurology for medical and dental students.
Supervising medical student elective and MSc projects
Non-course Teaching Responsibilities
Regent to medical students
- Publications
-
Page 1 of 18 Results 1 to 10 of 180
Cognitive and Motor Decline in Dementia with Lewy Bodies and Parkinson's Disease Dementia
Movement Disorders Clinical PracticeContributions to Journals: Articles- [ONLINE] DOI: https://doi.org/10.1002/mdc3.13752
- [ONLINE] View publication in Scopus
The evolution of diagnosis from symptom onset to death in progressive supranuclear palsy (PSP) and corticobasal degeneration (CBD) compared to Parkinson's disease (PD)
Journal of NeurologyContributions to Journals: ArticlesAchieving proportionate governance review in Scotland: Threats and solutions
Journal of the Royal College of Physicians of Edinburgh, vol. 53, no. 1, pp. 74-79Contributions to Journals: Comments and Debates- [ONLINE] DOI: https://doi.org/10.1177/14782715231153033
- [ONLINE] View publication in Scopus
Is the assumption of waning of treatment effect applied consistently across NICE technology appraisals?: A case-study focusing on disease-modifying therapies for treatment of multiple sclerosis
International Journal of Technology Assessment in Health Care, vol. 38, no. 1, pp. e83Contributions to Journals: Review articlesThe incidence, baseline predictors and outcomes of dementia in an incident cohort of Parkinson’s disease and controls
Journal of Neurology, vol. 269, pp. 4288–4298Contributions to Journals: ArticlesSystematic review of prevalence studies of progressive supranuclear palsy and corticobasal syndrome
Movement Disorders Clinical Practice, vol. 9, no. 5, pp. 604-613Contributions to Journals: ArticlesManagement of the first stage of convulsive status epilepticus in adults: a systematic review of current randomised evidence
Journal of Neurology, vol. 269, no. 7, pp. 3420-3429Contributions to Journals: Review articlesPrevalence of progressive supranuclear palsy and corticobasal syndrome in Scotland
Neuroepidemiology, vol. 56, no. 4, pp. 291–297Contributions to Journals: ArticlesGBA and APOE Impact Cognitive Decline in Parkinson's Disease: A 10-Year Population-Based Study
Movement Disorders, vol. 37, no. 5, pp. 1016-1027Contributions to Journals: Articles- [ONLINE] DOI: https://doi.org/10.1002/mds.28932
- [OPEN ACCESS] http://aura.abdn.ac.uk/bitstream/2164/18036/1/Szwedo_etal_MD_GBA_And_APOE_VoR.pdf
- [ONLINE] View publication in Scopus
Pre-hospital and emergency department treatment of convulsive status epilepticus in adults: an evidence synthesis
Health technology assessment (Winchester, England), vol. 26, no. 20, pp. 1-76Contributions to Journals: Articles