We host two registries of patients with Spondyloarthritis and are currently establishing a register of patients with Psoriatic Arthritis.

SIRAS

The Scotland Registry for Ankylosing Spondylitis includes details of patients seen in secondary care in Scotland with a clinical diagnosis of Ankylosing Spondyliitis.  Approximately 2000 patients are included in the registry and those who have provided consent are being followed annually for two years.

BSRBR-AS

The British Society for Rheumatology Biologics Register in Ankylosing Spondylitis (BSRBR-AS) tracks the progress of a cohort of patients with axial spondyloarthritis who are taking biologic therapy, plus a comparison cohort of patients not on these drugs.

This register is a collaboration between the University of Aberdeen and the British Society for Rheumatology. We currently have 84 centres recruiting throughout Great Britain. Study recruitment started in December 2012 and will continue through to December 2017. Follow-up will take place until December 2018.

The Team

  BSRBR-AS Team 2016

Address

BSRBR-AS Co-ordinating centre
Epidemiology Group, University of Aberdeen
Health Sciences Building, Foresterhill
Aberdeen Scotland AB25 2ZD

Email: bsrbr-as@abdn.ac.uk
Telephone: 01224 437141

Healthcare Teams

This study is no longer open for new centres to join. However if you are currently participating in BSRBR-AS then you may access from this page the data management system, which includes eCRF, pharmacovigilance reporting, and current approval documents.

To find out more about Data Collection please click here.

Current Approved Documents 29 June 2017

(post AM10 approval)

Document

Version

Date

Protocol

15.0

19/01/2017

Genetics Informaiton sheet and consent form

7.0

26/08/2014

Genetics kit covering letter

4.0

26/08/2014

Genetics kit reminder letter

5.0

26/08/2014

Participant Baseline Questionnaire

7.0

16/03/2016

Participant information sheet and consent form

8.0

27/07/2016

Pre-clinic infomation sheet

4.0

27/07/2016

Follow up Questionnaire

2.0

15/03/2016

Participant cover letter for partner pregnancy

1.0

05/05/2016

Partner cover letter for partner pregnancy

1.0

05/05/2016

Partner information sheet

1.0

05/05/2016

Partner's pregancy questionnaire

2.0

27/07/2016

Patient diary booklet

2.0

14/10/2013

Pre-clinic covering letter

4.0

08/11/2013

Pre-clinic covering letter with reply slip

1.0

15/10/2013

Follow up questionnaire letter

2.0

24/10/2013

Follow up questionnaire reminder letter

2.0

24/10/2013

For Archived documents please click here.

Patients

The British Society for Rheumatology is currently co-ordinating a study to examine the effectiveness and safety of biologic therapies in the management of Ankylosing Spondylitis (AS). We are recruiting, through clinical centres, AS patients who are starting a new biologic therapy for the first time and a comparator group of patients who are not starting biologic therapy and who have never previously been prescribed such therapy. Currently in the UK the biologic therapies licensed for use in Axial Spondyloarthritis (including AS) are:

Biologic Agent Pharmaceutical company
Humira (Adalimumab) AbbVie
Enbrel (Etanercept) Pfizer
Cimzia (Certolizumab Pegol) UCB
Benepali (Etanercept) Biogen
Simponi (Golimumab) Janssen
Inflectra (Infliximab) Hospira (Pfizer)
Remicade (Infliximab) Janssen
Remsima (Infliximab) Celltrion
Consentyx (Secukinumab) Novartis

 

The following centres are currently open for recruitment. If you are an AS patient who attends one of these centres, you can ask your clinical team if you are eligible to take part.

Centres currently  open for recruitment

Aberdeen Royal Infirmary

Northwick Park Hospital, Harrow

Addenbrooke's Hospital, Cambridge

Nottingham City Hospital

Barnet General Hospital

Peterborough City Hospital

Barnsley District General Hospital

Pinderfields General Hospital, Wakefield

Basingstoke and North Hampshire Hospital

Poole Hospital

Blackpool Victoria Hospital

Queen Alexandra Hospital, Portsmouth

Broadgreen Hospital, Liverpool

Queen's Hospital Burton

Cannock Chase Hospital

Raigmore Hospital, Inverness

Chapel Allerton Hospital, Leeds

Robert Jones & Agnes Hunt Orthopaedic Hospital, Oswestry

City Hospital, Birmingham

Royal Berkshire Hospital, Reading

Coventry University Hospital

Royal Blackburn Hospital

Cumberland Infirmary, Carlisle

Royal Cornwall Hospital

Derriford Hospital, Plymouth

Royal Derby Hospital

Eastbourne District General Hospital

Royal Free Hospital, London

Epsom and St Helier Hospitals

Royal Hallamshire Hospital, Sheffield

Fairfield General Hospital

Royal Lancaster Infirmary

Freeman Hospital, Newcastle

Royal National Hospital of Rheumatic Diseases, Bath

Glasgow Royal Infirmary

Russells Hall Hospital, Dudley

Southern General Hospital, Glasgow

Salisbury District Hospital

Guy's Hospital, London

Scarborough General Hospital

Haywood Hospital, Stoke on Trent

Scunthorpe General Hospital

Homerton Hospital, London

Southampton General Hospital

Hull Royal Infirmary

Southend Hospital

Ipswich Hospital

Southmead Hospital, Bristol

James Cook University Hospital

St Helen's Hospital

Kings College Hospital, London

St Peter's Hospital, Chertsey

King's Mill Hospital,  Sutton-In-Ashfield

Sunderland Royal Hospital

Leicester Royal Infirmary

Torbay Hospital

Leighton Hospital, Crewe

Tunbridge Wells Hospital

Lincoln County Hospital

University Hospital Aintree, Liverpool

Lister Hospital

University Hospital of North Durham

Llandudno Hospital

Warrington Hospital

Luton & Dunstable Hospital

Warwick Hospital

Macclesfield District General

Weston General Hospital

Maidstone Hospital

Whyteman's Brae Hospital, Fife

Manchester Royal Infirmary

Wishaw General Hospital

Minerva Health Centre, Preston

Wrightington Hospital, Wigan

New Cross Hospital, Wolverhampton

Wythenshawe Hospital, Manchester

Ninewells Hospital, Dundee

York Hospital

Norfolk and Norwich University Hospital

Ysbyty Maelor, Wrexham

Northampton General Hospital

 

Newsletters

The coordinating centre produce a quarterly newsletter providing an update on the study, as well as recruitment figures.

 

Contributor list

The full list of persons contributing to the BSRBR-AS can be found here.

BSRBR-PsA

The British Society for Rheumatology Biologics Register in Psoriatic Arthritis is currently being established. It will commence in 2017, be UK-wide and of similar design to BSRBR-AS.