Dr Daria Antipova (MD, MSc)

Title of PhD Project: Designing a pre-hospital scoring system for the prediction of haemorrhagic and ischaemic stroke

Dates: April 2017 to March 2020

Description:

Stroke is one of the major causes of death and disability in adults worldwide. Once a stroke patient arrives at hospital they have a CT scan of their brain to determine whether the stroke is caused by a blocked artery or bleeding to guide the definitive treatment. Stroke patients might benefit greatly if they were treated before getting to hospital, particularly in rural areas where transit times are long.

The aim of our research is to develop a new type of scoring system to predict stroke type. Stroke patients admitted to Raigmore Hospital (Inverness) will be recruited.  Their brains will be scanned quickly using an ultrasound machine.  They will also be scanned as normal in line with standard hospital practice. A scoring system will be based upon what we see with ultrasound, together with other important demographic and clinical data. The end result could potentially be improved survival, reduced morbidity and consequent reduced health service and social costs.

Supervisory team:

Professor Philip Wilson, Director of Centre for Rural Health

Dr Leila Eadie, Research Fellow, Centre for Rural Health

Dr Ashish Stephen MacAden, Consultant in Rehabilitation Medicine and Stroke, Raigmore Hospital, NHS Highland


Additional Short Study:

Study title

Rapid assessment using transcranial ultrasound: pilot study with novice users

Dates

May – July 2019

Overview and aims

Responding to stroke in remote and rural areas is difficult. It can take a long time for an ambulance to reach patients and then transport them back to hospital to work out whether strokes are being caused by bleeding or by blood clots blocking the arteries.  Acting quickly is very important as the longer the patient waits for assessment and treatment, the poorer their outcome will be.

 

The most common methods of looking for signs of occluded vessel or bleeding in the brain use large scanners which are bulky and not readily portable. Ultrasound scanners can be very portable and can therefore be used in ambulances and other situations outside of a hospital.

 

This study contributes to the ongoing project ‘Designing a prehospital scoring system for the prediction of haemorrhagic stroke and ischaemic stroke’ (https://www.abdn.ac.uk/iahs/research/crh/projects/daria-antipova-phd-1257.php).

It is looking at the practicality and effectiveness of brief training provided for novice transcranial ultrasound users to ensure that they are able to acquire a pre-specified set of images and video clips of satisfactory quality which could then be transferred for expert interpretation and decision making.

 

We are aiming to recruit a maximum of 15 volunteers among qualified clinicians or students of Nursing or Medicine. Participants will receive three-hour training  on transcranial grey-scale and colour-coded duplex sonography to visualise cerebral landmarks and major cerebral blood vessels. This will involve transcranial ultrasound scanning of healthy volunteers through the temporal bone windows.

 

If the training programme is successful, it could be used in the future to provide training for a wider audience of GPs working in remote and rural areas, community physicians and ambulance paramedics. This could also help ensure speedier and more effective prehospital treatment.

 

Funding

This study is run and funded by the University of Aberdeen.

 

Contact

Daria Antipova on 01463 255902 or email daria.antipova@abdn.ac.uk