Dr Stephen Makin

Dr Stephen Makin
Dr Stephen Makin
Dr Stephen Makin


Senior Lecturer (Clinical)

Email Address
Office Address

Centre for Rural Health 
The Centre for Health Science
Old Perth Road

School of Medicine, Medical Sciences and Nutrition


As well as my clinical academic work, I am a geriatrician with my clinical practice at Catihness General Hospital in Wick a small rural hospital in the far north of Scotland. 

After training at the University of Birmingham, and post graduate training in North West England, I moved to Scotland to do a Clinical Research fellow post at the University of Edinburgh. My PhD focused on small vessel disease. Diffuse vascular disease that is very common in older people, and is responsible for vascular dementia, lacunar stroke, gait instablity as well as other co-morbidities. 

I am still interested in stroke but in addition I am now also investigating the  best way to deliever health care to frail elderly patients in remote and rural areas. 

I am always keen to collaborate and welcome enquires from prospective collaborators and research students. 


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  • Clinical Associations and Prognostic Value of MRI-Visible Perivascular Spaces in Patients With Ischemic Stroke or TIA: A Pooled Analysis

    Best, J. G., Ambler, G., Wilson, D., Du, H., Lee, K. J., Lim, J. S., Teo, K. C., Mak, H., Kim, Y. D., Song, T. J., Selcuk Demirelli, D., Nishihara, M., Yoshikawa, M., Kubacka, M., Zietz, A., Al-Shahi Salman, R., Jäger, H. R., Lip, G. Y., Panos, L., Goeldlin, M. B., Slater, L. A., Karayiannis, C. C., Phan, T. G., Bellut, M., Abrigo, J., Cheng, C., Leung, T. W., Chu, W., Chappell, F., Makin, S. D., Van Dam-Nolen, D. H., Kooi, M. E., Köhler, S., Staals, J., Kuchcinski, G., Bordet, R., Dubost, F., Wardlaw, J. M., Soo, Y. O., Fluri, F., Srikanth, V. K., Jung, S., Peters, N., Hara, H., Yakushiji, Y., Necioglu Orken, D., Heo, J. H., Lau, G. K. K., Bae, H. J., Werring, D. J.
    Neurology, vol. 102, no. 1, e207795
    Contributions to Journals: Articles
  • Validated frailty measures using electronic primary care records: a review of diagnostic test accuracy

    Brack, C., Kynn, M., Murchie, P., Makin, S.
    Age and Ageing, vol. 52, no. 11, afad173
    Contributions to Journals: Articles
  • Sex Differences in Poststroke Cognitive Impairment: A Multicenter Study in 2343 Patients With Acute Ischemic Stroke

    Exalto, L. G., Weaver, N. A., Kuijf, H. J., Aben, H. P., Bae, H. J., Best, J. G., Bordet, R., Chen, C. P., Van Der Giessen, R. S., Godefroy, O., Gyanwali, B., Hamilton, O. K., Hilal, S., Huenges Wajer, I. M., Kim, J., Kappelle, L. J., Kim, B. J., Köhler, S., De Kort, P. L., Koudstaal, P. J., Lim, J. S., Makin, S. D., Mok, V. C., Van Oostenbrugge, R. J., Roussel, M., Staals, J., Valdés-Hernández, M. D. C., Venketasubramanian, N., Verhey, F. R., Wardlaw, J. M., Werring, D. J., Xu, X., Van Zandvoort, M. J., Biesbroek, J. M., Chappell, F. M., Biessels, G. J.
    Stroke, vol. 54, no. 9, pp. 2296-2303
    Contributions to Journals: Articles
  • Impact of Cerebral Microbleeds in Stroke Patients with Atrial Fibrillation

    Soo, Y., Zietz, A., Yiu, B., Mok, V. C. T., Polymeris, A. A., Seiffge, D., Ambler, G., Wilson, D., Leung, T. W. H., Tsang, S. F., Chu, W., Abrigo, J., Cheng, C., Lee, K., Lim, J., Shiozawa, M., Koga, M., Chabriat, H., Hennerici, M., Wong, Y. K., Mak, H., Collet, R., Inamura, S., Yoshifuji, K., Arsava, E. M., Horstmann, S., Purrucker, J., Lam, B. Y. K., Wong, A., Kim, Y. D., Song, T., Lemmens, R., Eppinger, S., Gattringer, T., Uysal, E., Demirelli, D. S., Bornstein, N. M., Assayag, E. B., Hallevi, H., Molad, J., Nishihara, M., Tanaka, J., Coutts, S. B., Kappelle, L. J., Al-Shahi Salman, R., Jager, R., Lip, G. Y. H., Goeldlin, M. B., Panos, L. D., Mas, J., Legrand, L., Karayiannis, C., Phan, T., Bellut, M., Chappell, F., Makin, S., Hayden, D., Williams, D., van Dam-Nolen, D. H. K., Nederkoorn, P. J., Barbato, C., Browning, S., Wiegertjes, K., Tuladhar, A. M., Mendyk, A., Köhler, S., van Oostenburgge, R., Zhou, Y., Xu, C., Hilal, S., Gyanwali, B., Chen, C., Lou, M., Staals, J., Bordet, R., Kandiah, N., de Leeuw, F., Simister, R., Hendrikse, J., Wardlaw, J., Kelly, P., Fluri, F., Srikanth, V., Calvet, D., Jung, S., Kwa Vincent, I. H., Smith, E. E., Hara, H., Yakushiji, Y., Orken, D. N., Fazekas, F., Thijs, V., Heo, J., Veltkamp, R., Ay, H., Imaizumi, T., Lau, K. K., Jouvent, E., Toyoda, K., Yoshimura, S., Bae, H., Martí-Fàbregas, J., Prats-Sánchez, L., Lyrer, P., Best, J., Werring, D., Engelter, S. T., Peters, N., Network, t. M. I. C.
    Annals of Neurology, vol. 94, no. 1, pp. 61-74
    Contributions to Journals: Articles
  • Development of a UK core dataset for geriatric medicine research:: a position statement and results from a Delphi consensus process

    Welch, C., Wilson, D., Sayer, A. A., Witham, M. D., Jackson, T. A., Rajkumar, R., Dhesi, J., Lochlainn, M. N., Aspray, T., Dodds, R., Frith, J., Richardson, S., Tullo, E., Yarnall, A., Walker, R., Cunningham, E., Prynn, J., Patel, H., Tiwari, D., Makin, S., Myint, P., Henderson, E., Keevil, V., Walesby, K., Allan, L., Masoli, J., Quinn, T., Clegg, A. P., Hale, M., Conroy, S., Taylor, J., Gladman, J., Gordon, A., Harwood, R., Cox, N., Roberts, H., UK Geriatric Medicine Core Dataset Extended Working Group
    BMC Geriatrics, vol. 23, 168
    Contributions to Journals: Articles
  • Predicting incident dementia in cerebral small vessel disease: comparison of machine learning and traditional statistical models

    Li, R., Harshfield, E. L., Bell, S., Burkhart, M., Tuladhar, A. M., Hilal, S., Tozer, D. J., Chappell, F. M., Makin, S. D., Lo, J. W., Wardlaw, J. M., de Leeuw, F. E., Chen, C., Kourtzi, Z., Markus, H. S.
    Cerebral Circulation - Cognition and Behavior, vol. 5, 100179
    Contributions to Journals: Articles

    Makin, S., Brack, C., Kynn, M., Murchie, P.
    Age and Ageing, vol. 51, no. SUPPL 2, 1013
    Contributions to Journals: Abstracts
  • Network impact score is an independent predictor of post-stroke cognitive impairment: a multicenter cohort study in 2341 patients with acute ischemic stroke.

    Weaver, N. A., Aben, H. P., Kuijf, H. J., Abrigo, J., Bae, H., Barbay, M., Best, J. G., Bordet, R., Chappell, F. M., Chen, C. P., Dondaine, T., van der Giessen, R. S., Godefroy, O., Gyanwali, B., Hamilton, O. K., Hilal, S., Huenges Wajer, I. M., Kang, Y., Kappelle, L. J., Kim, B. J., Köhler, S., de Kor, P. L., Koudstaal, P. J., Kuchcinski, G., Lam, B. Y., Lee, B., Lee, K., Lim, J., Lopes, R., Makin, S., Mendyk, A., Mok, V. C., Oh, M. S., Van Oostenbrugge, R. J., Roussel, M., Shi, L., Staals, J., Valdés Hernández, M. D. C., Venketasubramanian, N., Verhey, F. R., Wardlaw, J. M., Werring, D. J., Xin, X., Yu, K., van Zandvoort, M. J., Zhao, L., Biessels, G. J., Biesbroek, J.
    NeuroImage: Clinical, vol. 34, 103018
    Contributions to Journals: Articles
  • Impact of Small Vessel Disease Progression on Long-term Cognitive and Functional Changes after Stroke

    Clancy, U., Makin, S. D., McHutchison, C. A., Cvoro, V., Chappell, F. M., Hernández, M. D. C., Sakka, E., Doubal, F., Wardlaw, J. M.
    Neurology, vol. 98, no. 14, pp. E1459-E1469
    Contributions to Journals: Articles
  • Tracer kinetic assessment of blood–brain barrier leakage and blood volume in cerebral small vessel disease: Associations with disease burden and vascular risk factors

    Stringer, M. S., Heye, A. K., Armitage, P. A., Chappell, F., Valdés Hernández, M. d. C., Makin, S. D., Sakka, E., Thrippleton, M. J., Wardlaw, J. M.
    NeuroImage: Clinical, vol. 32, 102883
    Contributions to Journals: Articles
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