Our work covers a number of related research topics that span from discovery science to translational projects, aiming for first-in-man studies. These include

  • Identifying the native stem/stromal cells that maintain and repair joints
  • Understanding the origins of the stem/stromal cells in the joint
  • Understanding how the native stem/stromal cells contribute to joint pathophysiology in osteoarthritis and in inflammatory arthritis
  • Understanding the molecular factors that regulate joint stem/stromal cells in health and arthritis in order to identify new therapeutic targets
  • Developing novel therapeutic strategies to target stem/stromal cells in the joint

Our research is also part of consortia aiming to

  • Develop novel tissue engineering products for cartilage and bone repair
  • Discover biomarkers of identity and potency of cell preparations