Publications | The School of Biological Sciences

Graded calorie restriction causes graded slowing of epigenetic aging in mice

2025 - Accepted/In press

Speakman, J., Chen, E., Moulds, T., Mitchell, S., Guo, W., Yang, X., Adams, P.

Aging Cell

Contributions to Journals: Articles

Digital Object Identifier: https://doi.org/10.1111/acel.70342

Effects of graded calorie restriction: XXII. Impact of long-term graded calorie restriction on tissue partitioning, digestive efficiency, bone health, and coordination in male C57BL/6J mice

2025

Mitchell, S., Heib, L., Green, C. L., Derous, D., Hambly, C., Speakman, J.

The Journals of Gerontology. Series A, Biological Sciences and Medical Sciences, vol. 80, no. 11, glaf168

Contributions to Journals: Articles

Digital Object Identifier: https://doi.org/10.1093/gerona/glaf168
Open Access: http://aura.abdn.ac.uk/bitstreams/3ab5e65f-aea9-4def-a762-cb885acca2bc/download

Predictive equation derived from 6,497 doubly labelled water measurements enables the detection of erroneous self-reported energy intake

2025

Bajunaid, R., Niu, C., Hambly, C., Liu, Z., Yamada, Y., Aleman-Mateo, H., Anderson, L. J., Arab, L., Baddou, I., Bandini, L., Bedu-Addo, K., Blaak, E. E., Bouten, C. V. C., Brage, S., Buchowski, M. S., Butte, N. F., Camps, S. G. J. A., Casper, R., Close, G. L., Cooper, J. A., Cooper, R., Das, S. K., Davies, P. S. W., Dabare, P., Dugas, L. R., Eaton, S., Ekelund, U., Entringer, S., Forrester, T., Fudge, B. W., Gillingham, M., Goris, A. H., Gurven, M., El Hamdouchi, A., Haisma, H. H., Hoffman, D., Hoos, M. B., Hu, S., Joonas, N., Joosen, A. M., Katzmarzyk, P., Kimura, M., Kraus, W. E., Kriengsinyos, W., Kuriyan, R., Kushner, R. F., Lambert, E. V., Lanerolle, P., Larsson, C. L., Leonard, W. R., Lessan, N., Löf, M., Martin, C. K., Matsiko, E., Medin, A. C., Morehen, J. C., Morton, J. P., Must, A., Neuhouser, M. L., Nicklas, T. A., Nyström, C. D., Ojiambo, R. M., Pietiläinen, K. H., Pitsiladis, Y. P., Plange-Rhule, J., Plasqui, G., Prentice, R. L., Racette, S. B., Raichlen, D. A., Ravussin, E., Redman, L. M., Reilly, J. J., Reynolds, R., Roberts, S. B., Samaranayakem, D., Sardinha, L. B., Silva, A. M., Sjödin, A. M., Stamatiou, M., Stice, E., Urlacher, S. S., Van Etten, L. M., van Mil, E. G. A. H., Wilson, G., Yanovski, J. A., Yoshida, T., Zhang, X., Murphy-Alford, A. J., Sinha, S., Loechl, C. U., Luke, A. H., Pontzer, H., Rood, J., Sagayama, H., Schoeller, D. A., Westerterp, K. R., Wong, W. W., Speakman, J. R.

Nature Food, vol. 6, pp. 58-71

Contributions to Journals: Articles

Digital Object Identifier: https://doi.org/10.1038/s43016-024-01089-5
Open Access: http://aura.abdn.ac.uk/bitstreams/ce0bc095-8b09-476f-a7fc-0bf61dcb1a65/download

Improving quality control procedures for the measurement of total daily energy expenditure using the two-point doubly labeled water method

2024

Breit, M. J., Duncan, N. M., Dahle, J. H., Catenacci, V. A., Creasy, S. A., Berman, E. S., Speakman, J. R., Melanson, E. L.

Rapid Communications in Mass Spectrometry, vol. 38, no. 19, e9886

Contributions to Journals: Articles

Online: https://pmc.ncbi.nlm.nih.gov/articles/PMC12084875/
Digital Object Identifier: https://doi.org/10.1002/rcm.9886
Additional Links: View publication in Scopus

Reproduction has immediate effects on female mortality, but no discernible lasting physiological impacts: A test of the disposable soma theory

2024

Mitchell, S. E., Simpson, M., Coulet, L., Gouedard, S., Hambly, C., Morimoto, J., Allison, D. B., Speakman, J. R.

Proceedings of the National Academy of Sciences of the United States of America, vol. 121, no. 42, e2408682121

Contributions to Journals: Articles

Digital Object Identifier: https://doi.org/10.1073/pnas.2408682121
Open Access: http://aura.abdn.ac.uk/bitstreams/77f23679-e0a5-490b-82bb-5e2e7155f0f0/download
Additional Links: View publication in Scopus

Benefits of calorie restriction in mice are mediated via energy imbalance, not absolute energy or protein intake

2024

Smith, D. L., Mitchell, S. E., Johnson, M. S., Gibbs, V. K., Dickinson, S., Henschel, B., Li, R., Kaiser, K. A., Chusyd, D. E., Brown, A. W., Allison, D. B., Speakman, J. R., Nagy, T. R.

GeroScience, vol. 46, pp. 4809–4826

Contributions to Journals: Articles

Digital Object Identifier: https://doi.org/10.1007/s11357-024-01166-4
Open Access: http://aura.abdn.ac.uk/bitstreams/ef4c69c8-cb7d-458d-b8fb-bf535850e3ef/download

On the pathogenesis of obesity: causal models and missing pieces of the puzzle

2024

Magkos, F., Sørensen, T. I., Raubenheimer, D., Dhurandhar, N. V., Loos, R. J., Bosy-Westphal, A., Clemmensen, C., Hjorth, M. F., Allison, D. B., Taubes, G., Ravussin, E., Friedman, M. I., Hall, K. D., Ludwig, D. S., Speakman, J. R., Astrup, A.

Nature Metabolism, vol. 6, no. 10, pp. 1856-1865

Contributions to Journals: Articles

Digital Object Identifier: https://doi.org/10.1038/s42255-024-01106-8
Additional Links: View publication in Scopus

Not feeling the heat?: Effects of dietary protein on satiation and satiety in mice are not due to its impact on body temperature.

2024

Osorio Mendoza, J., Mitchell, S., Hambly, C., Allison, D. B., Speakman, J.

Appetite, vol. 200, 107421

Contributions to Journals: Articles

Digital Object Identifier: https://doi.org/10.1016/j.appet.2024.107421
Open Access: http://aura.abdn.ac.uk/bitstreams/c7e4825a-7182-4cb1-9b94-a26dd88f996f/download

Validity of dietary assessment methods compared with doubly labeled water in children: A systematic review and meta-analysis

2024

Mehranfar, S., Jalilpiran, Y., Jafari, A., Jayedi, A., Shab-bidar, S., Speakman, J. R., Djafarian, K.

Obesity Reviews, vol. 25, no. 9, e13768

Contributions to Journals: Review articles

Digital Object Identifier: https://doi.org/10.1111/obr.13768
Additional Links: View publication in Scopus

Energy expenditure, intake and availability in female soccer players via doubly labelled water: Are we misrepresenting low energy availability?

2024 - E-pub ahead of print

McHaffie, S. J., Langan-Evans, C., Strauss, J. A., Areta, J. L., Rosimus, C., Evans, M., Waghorn, R., Grant, J., Cuthbert, M., Hambly, C., Speakman, J. R., Morton, J. P.

Experimental Physiology

Contributions to Journals: Articles

Digital Object Identifier: https://doi.org/10.1113/EP091589
Additional Links: View publication in Scopus

Daily energy expenditure and water turnover in female netball players from the Netball Super League: A doubly labeled water observation study

2024

Costello, N., Jones, B., Roe, S., Blake, C., Clark, A., Chantler, S., Owen, C., Wilson, L., Wilson, O., Stavropoulos-Kalinoglou, A., Janse van Rensburg, D. C., Hambly, C., Speakman, J. R., Backhouse, S., Whitehead, S.

European Journal of Sport Science, vol. 24, no. 8, pp. 1130-1142

Contributions to Journals: Articles

Digital Object Identifier: https://doi.org/10.1002/ejsc.12160
Open Access: http://aura.abdn.ac.uk/bitstreams/cef55f3c-08f2-49dd-9dce-404ea1265ebb/download
Additional Links: View publication in Scopus

Validity of predictive equations for total energy expenditure against doubly labeled water

2024

Prado-Nóvoa, O., Howard, K. R., Laskaridou, E., Zorrilla-Revilla, G., Reid, G. R., Marinik, E. L., Davy, B. M., Stamatiou, M., Hambly, C., Speakman, J. R., Davy, K. P.

Scientific Reports, vol. 14, 15754

Contributions to Journals: Articles

Digital Object Identifier: https://doi.org/10.1038/s41598-024-66767-7
Open Access: http://aura.abdn.ac.uk/bitstreams/8677aacf-430e-459d-afb4-02a86b3dfa99/download
Additional Links: View publication in Scopus

The carbohydrate insulin model is always correct: a point worth reiterating even when commenting on studies that do not concern it

2024

Speakman, J. R., Gao, L., Hu, S.

Obesity, vol. 32, no. 7, pp. 1229-1230

Contributions to Journals: Letters

Digital Object Identifier: https://doi.org/10.1002/oby.24053
Additional Links: View publication in Scopus

Carbon, nitrogen, and sulfur elemental and isotopic variations in mouse hair and bone collagen during short-term graded calorie restriction

2024

Gutierrez, E., Mitchell, S., Hambly, C., Sayle, K. l., Von kriegsheim, A., Speakman, J. r., Britton, K.

iScience, vol. 27, no. 6, 110059

Contributions to Journals: Articles

Digital Object Identifier: https://doi.org/10.1016/j.isci.2024.110059
Open Access: http://aura.abdn.ac.uk/bitstreams/ed1dc7b3-9204-44a7-9301-062fb4d8b983/download

Results of the Second Life Metabolism Travel Awards 2024

2024

Speakman, J. R.

Life metabolism, vol. 3, no. 3, loae007

Contributions to Journals: Articles

Digital Object Identifier: https://doi.org/10.1093/lifemeta/loae007
Open Access: http://aura.abdn.ac.uk/bitstreams/46575609-7de1-4d8c-a37b-6e1e67289425/download

Loss of GPR75 protects against non-alcoholic fatty liver disease and body fat accumulation

2024

Leeson-Payne, A., Iyinikkel, J., Malcolm, C., Lam, B. Y. H., Sommer, N., Dowsett, G. K. C., Blanco Martinez de Morentin, P., Thompson, D., MacKenzie, A., Chianese, R., Kentistou, K. A., Gardner, E. J., Perry, J. R., Grassmann, F., Speakman, J., Rochford, J., Yeo, G. S. H., Murray, F., Heisler, L.

Cell Metabolism, vol. 36, no. 5, pp. 1076-1087

Contributions to Journals: Articles

Digital Object Identifier: https://doi.org/10.1016/j.cmet.2024.03.016
Open Access: http://aura.abdn.ac.uk/bitstreams/a4df5e6e-2e39-4d4b-9f5b-ca50333bb251/download

Turmeric shortens lifespan in houseflies

2024

Laurie, S., Ainslie, L., Mitchell, S., Morimoto, J.

Frontiers in Insect Science, vol. 4, 1376011

Contributions to Journals: Articles

Digital Object Identifier: https://doi.org/10.3389/finsc.2024.1376011
Open Access: http://aura.abdn.ac.uk/bitstreams/2c9bcab3-98c8-43a3-aa96-33b89e11842f/download
Additional Links: View publication in Scopus

Case-study: Energy expenditure of a world class male wheelchair tennis player during training, Grand Slam and British open tournaments measured by doubly labelled water

2024

Ellis, D. G., Speakman, J., Hambly, C., Cockram, A., Morton, J. P., Close, G. L., Donovan, T. F.

International Journal of Sports Science and Coaching, vol. 19, no. 2, pp. 857 - 863

Contributions to Journals: Articles

Digital Object Identifier: https://doi.org/10.1177/17479541231169033
Open Access: http://aura.abdn.ac.uk/bitstreams/b42aa800-6271-4676-92f1-bf6d3b42971f/download
Additional Links: View publication in Scopus

The hedonic overdrive model best explains high-fat diet-induced obesity in C57BL/6 mice

2024

Gao, L., Hu, S., Yang, D., Wang, L., Togo, J., Wu, Y., Li, B., Li, M., Wang, G., Zhang, X., Li, L., Xu, Y., Mazidi, M., Couper, E., Whittington-Davies, A., Niu, C., Speakman, J.

Obesity, vol. 32, no. 4, pp. 733-742

Contributions to Journals: Articles

Digital Object Identifier: https://doi.org/10.1002/oby.23991
Open Access: http://aura.abdn.ac.uk/bitstreams/c26a8d46-7e83-43a7-b8f7-982e046d1006/download

Links between energy budgets, somatic condition, and life history reveal heterogeneous energy management tactics in a group-living mesocarnivore

2024

Bright Ross, J. G., Markham, A., Buesching, C. D., Hambly, C., Speakman, J. R., Macdonald, D. W., Newman, C.

Movement Ecology, vol. 12, 24

Contributions to Journals: Articles

Digital Object Identifier: https://doi.org/10.1186/s40462-024-00453-1
Open Access: http://aura.abdn.ac.uk/bitstreams/32dd1aef-edeb-4883-b315-b34af929bc99/download

Maternal dietary fat during lactation shapes single nucleus transcriptomic profile of postnatal offspring hypothalamus in a sexually dimorphic manner in mice

2024

Huang, Y., Wang, A., Zhou, W., Li, B., Zhang, L., Rudolf, A. M., Jin, Z., Hambly, C., Wang, G., Speakman, J. R.

Nature Communications, vol. 15, 2382

Contributions to Journals: Articles

Digital Object Identifier: https://doi.org/10.1038/s41467-024-46589-x
Open Access: http://aura.abdn.ac.uk/bitstreams/8c5adf29-546c-4892-bc9c-55b9998a8bd6/download
Additional Links: View publication in Scopus

Behavioural variability, physical activity, rumination time, and milk characteristics of dairy cattle in response to regrouping

2024

Marumo, J. L., Lusseau, D., Speakman, J. R., Mackie, M., Byar, A. Y., Cartwright, W., Hambly, C.

Animal , vol. 18, no. 3, 101094

Contributions to Journals: Articles

Digital Object Identifier: https://doi.org/10.1016/j.animal.2024.101094
Open Access: http://aura.abdn.ac.uk/bitstreams/bc17c30d-6f8c-4847-b03b-15fc0f1c74fc/download
Additional Links: View publication in Scopus

Limits to sustained energy intake. XXXIV.: Can the heat dissipation limit (HDL) theory explain reproductive aging?

2024

Grosiak, M., Koteja, P., Hambly, C., Speakman, J. R., Sadowska, E. T.

The Journal of experimental biology, vol. 227, no. 4, jeb246592

Contributions to Journals: Articles

Digital Object Identifier: https://doi.org/10.1242/jeb.246592
Open Access: http://aura.abdn.ac.uk/bitstreams/67195986-6b95-40cf-b2a2-45d34c2a32ca/download

Wearable Sensors Based Human Core Body Temperature Computing Method

2023

Jiang, L., Wang, Y., Li, Y., Tao, B., Sun, F., Speakman, J.

Chapters in Books, Reports and Conference Proceedings: Conference Proceedings

Digital Object Identifier: https://doi.org/10.1109/DASC/PiCom/CBDCom/Cy59711.2023.10361403
Additional Links: View publication in Scopus

Daily energy requirements of male academy soccer players are greater than age-matched non-academy soccer players: A doubly labelled water investigation

2023

Stables, R. G., Hannon, M. P., Jacob, A. D., Topping, O., Costello, N. B., Boddy, L. M., Hambly, C., Speakman, J. R., Sodhi, J. S., Close, G. L., Morton, J. P.

Journal of Sports Sciences, vol. 41, no. 12, pp. 1218-1230

Contributions to Journals: Articles

Digital Object Identifier: https://doi.org/10.1080/02640414.2023.2263707
Open Access: http://aura.abdn.ac.uk/bitstreams/02302ed9-aa69-4acc-84aa-331fd7b1e395/download

Determining energy expenditure in a large seabird using accelerometry

2023

Sutton, G. J., Angel, L. P., Speakman, J. R., Arnould, J. P. Y.

The Journal of experimental biology, vol. 226, no. 23, jeb246922

Contributions to Journals: Articles

Digital Object Identifier: https://doi.org/10.1242/jeb.246922
Open Access: http://aura.abdn.ac.uk/bitstreams/2a9995a7-ba5b-4c5f-9902-e074b2836b93/download

Great tits (Parus major) in a west European temperate forest show little seasonal variation in metabolic energy requirements

2023

Pacioni, C., Sentís, M., Hambly, C., Speakman, J. R., Kerimov, A., Bushuev, A., Lens, L., Strubbe, D.

Journal of Thermal Biology, vol. 118, pp. 103748

Contributions to Journals: Articles

Digital Object Identifier: https://doi.org/10.1016/j.jtherbio.2023.103748

The bioelectrical impedance analysis (BIA) international database: aims, scope, and call for data

2023

Silva, A. M., Campa, F., Stagi, S., Gobbo, L. A., Buffa, R., Toselli, S., Silva, D. A. S., Gonçalves, E. M., Langer, R. D., Guerra-Júnior, G., Machado, D. R. L., Kondo, E., Sagayama, H., Omi, N., Yamada, Y., Yoshida, T., Fukuda, W., Gonzalez, M. C., Orlandi, S. P., Koury, J. C., Moro, T., Paoli, A., Kruger, S., Schutte, A. E., Andreolli, A., Earthman, C. P., Fuchs-Tarlovsky, V., Irurtia, A., Castizo-Olier, J., Mascherini, G., Petri, C., Busert, L. K., Cortina-Borja, M., Bailey, J., Tausanovitch, Z., Lelijveld, N., Ghazzawi, H. A., Amawi, A. T., Tinsley, G., Kangas, S. T., Salpéteur, C., Vázquez-Vázquez, A., Fewtrell, M., Ceolin, C., Sergi, G., Ward, L. C., Heitmann, B. L., da Costa, R. F., Vicente-Rodriguez, G., Cremasco, M. M., Moroni, A., Shepherd, J., Moon, J., Knaan, T., Müller, M. J., Braun, W., García-Almeida, J. M., Palmeira, A. L., Santos, I., Larsen, S. C., Zhang, X., Speakman, J. R., Plank, L. D., Swinburn, B. A., Ssensamba, J. T., Shiose, K., Cyrino, E. S., Bosy-Westphal, A., Heymsfield, S. B., Lukaski, H., Sardinha, L. B., Wells, J. C., Marini, E.

European Journal of Clinical Nutrition, vol. 77, pp. 1143–1150

Contributions to Journals: Articles

Digital Object Identifier: https://doi.org/10.1038/s41430-023-01310-x
Additional Links: AM at UCL Repository

The effects of graded levels of calorie restriction: XX. impact of long term graded calorie restriction on survival and body mass dynamics in male C57BL/6J mice

2023

Mitchell, S. E., Togo, J., Green, C. L., Derous, D., Hambly, C., Speakman, J. R.

The Journals of Gerontology. Series A, Biological Sciences and Medical Sciences, vol. 78, no. 11, pp. 1953-1963

Contributions to Journals: Articles

Digital Object Identifier: https://doi.org/10.1093/gerona/glad152
Open Access: http://aura.abdn.ac.uk/bitstreams/9f24775a-7131-4e02-bf5d-3481c97c1cea/download

Validation of the 2 × 24 h recall method and a 7-d web-based food diary against doubly labelled water in Danish adults

2023

Biltoft-Jensen, A., Ygil, K. H., Knudsen, L., Matthiessen, J., Fagt, S., Trolle, E., Nielsen, T. H., Hansen, D. M., Licht, C. L., Martens, M., Hambly, C., Speakman, J. R., Christensen, T.

British Journal of Nutrition, vol. 130, no. 8, pp. 1444-1457

Contributions to Journals: Articles

Digital Object Identifier: https://doi.org/10.1017/S0007114523000454
Open Access: http://aura.abdn.ac.uk/bitstreams/c05dea0f-bad5-434d-97d5-f77b726dc3e8/download
Additional Links: View publication in Scopus

Models of body weight and fatness regulation

2023

Speakman, J. R., Hall, K. D.

Causes of obesity, 20220231

Contributions to Journals: Review articles

Digital Object Identifier: https://doi.org/10.1098/rstb.2022.0231
Additional Links: View publication in Scopus

Phylogenetic signal in gut microbial community rather than in rodent metabolic traits

2023

Zhang, X., Khakisahneh, S., Liu, W., Zhang, X., Zhai, W., Cheng, J., Speakman, J. R., Wang, D.

National Science Review, vol. 10, no. 10, nwad209

Contributions to Journals: Articles

Digital Object Identifier: https://doi.org/10.1093/nsr/nwad209
Open Access: http://aura.abdn.ac.uk/bitstreams/bb3ac723-75d9-4e38-a5c4-401b3452b695/download

Greater male variability in daily energy expenditure develops through puberty

2023

Halsey, L. G., Careau, V., Ainslie, P. N., Alemán-Mateo, H., Andersen, L. F., Anderson, L. J., Arab, L., Baddou, I., Bandini, L., Bedu-Addo, K., Blaak, E. E., Blanc, S., Bonomi, A. G., Bouten, C. V. C., Bovet, P., Brage, S., Buchowski, M. S., Butte, N., Camps, S. G., Casper, R., Close, G. L., Colbert, L. H., Cooper, J. A., Cooper, R., Dabare, P., Das, S. K., Davies, P. S. W., Deb, S., Nyström, C. D., Dietz, W., Dugas, L. R., Eaton, S., Ekelund, U., Hamdouchi, A. E., Entringer, S., Forrester, T., Fudge, B. W., Gillingham, M., Goris, A. H., Gurven, M., Haisma, H., Hambly, C., Hoffman, D., Hoos, M. B., Hu, S., Joonas, N., Joosen, A., Katzmarzyk, P., Kempen, K. P., Wood, B., IAEA DLW Database Consortium

Biology Letters, vol. 19, no. 9, 20230152

Contributions to Journals: Articles

Digital Object Identifier: https://doi.org/10.1098/rsbl.2023.0152
Open Access: http://aura.abdn.ac.uk/bitstreams/b934dfa9-54ba-4be8-90af-a7ed074b354a/download

Preface: causes of obesity, theories, conjectures and evidence

2023

Allison, D. B., Sørensen, T. I. A., Hall, K. D., Speakman, J. R.

Causes of obesity, 20220200

Contributions to Journals: Editorials

Digital Object Identifier: https://doi.org/10.1098/rstb.2022.0200
Open Access: http://aura.abdn.ac.uk/bitstreams/1cd66405-546f-4424-9c57-8c4bc3fc2b6e/download

A step toward precision gerontology: Lifespan effects of calorie and protein restriction are consistent with predicted impacts on entropy generation

2023

Semerciöz-Oduncuoğlu, A. S., Mitchell, S. E., Özilgen, M., Yilmaz, B., Speakman, J. R.

Proceedings of the National Academy of Sciences of the United States of America, vol. 120, no. 37, e2300624120

Contributions to Journals: Articles

Digital Object Identifier: https://doi.org/10.1073/pnas.2300624120
Open Access: http://aura.abdn.ac.uk/bitstreams/4cc45c53-6979-412e-8ef8-8d05030a220a/download
Additional Links: View publication in Scopus

Quantifying physical activity energy expenditure based on doubly labelled water and basal metabolism calorimetry: what are we actually measuring?

2023

Speakman, J. R., Pontzer, H.

Current Opinion in Clinical Nutrition and Metabolic Care, vol. 26, no. 5, pp. 401-408

Contributions to Journals: Review articles

Digital Object Identifier: https://doi.org/10.1097/MCO.0000000000000937

Unanswered questions about the causes of obesity: Obesity is now a global pandemic, but there is little consensus about the causes.

2023

Speakman, J. R., Sørensen, T. I., Hall, K. D., Allison, D. B.

Science (New York, N.Y.), vol. 381, no. 6661, pp. 944-946

Contributions to Journals: Articles

Digital Object Identifier: https://doi.org/10.1126/science.adg2718
Additional Links: View publication in Scopus

Increased parental effort fails to buffer the cascading effects of warmer seas on common guillemot demographic rates

2023

Wanless, S., Albon, S. D., Daunt, F., Sarzo, B., Newell, M. A., Gunn, C., Speakman, J. R., Harris, M. P.

Journal of Animal Ecology, vol. 92, no. 8, pp. 1622-1638

Contributions to Journals: Articles

Digital Object Identifier: https://doi.org/10.1111/1365-2656.13944
Open Access: http://aura.abdn.ac.uk/bitstreams/92952826-e832-446f-b758-561a5495083d/download

GDF15 promotes weight loss by enhancing energy expenditure in muscle

2023

Wang, D., Townsend, L. K., DesOrmeaux, G. J., Frangos, S. M., Batchuluun, B., Dumont, L., Kuhre, R. E., Ahmadi, E., Hu, S., Rebalka, I. A., Gautam, J., Jabile, M. J. T., Pileggi, C. A., Rehal, S., Desjardins, E. M., Tsakiridis, E. E., Lally, J. S., Juracic, E. S., Tupling, A. R., Gerstein, H. C., Paré, G., Tsakiridis, T., Harper, M. E., Hawke, T. J., Speakman, J. R., Blondin, D. P., Holloway, G. P., Jørgensen, S. B., Steinberg, G. R.

Nature, vol. 619, no. 7968, pp. 143-150

Contributions to Journals: Articles

Digital Object Identifier: https://doi.org/10.1038/s41586-023-06249-4
Open Access: http://aura.abdn.ac.uk/bitstreams/66644dc5-efba-470a-a6f1-c4336075bbe2/download
Additional Links: View publication in Scopus

A Summer Heat Wave Reduced Activity, Heart Rate, and Autumn Body Mass in a Cold-Adapted Ungulate

2023

Trondrud, L. M., Pigeon, G., Król, E., Albon, S., Ropstad, E., Kumpula, J., Evans, A. L., Speakman, J. R., Loe, L. E.

Physiological and Biochemical Zoology, vol. 96, no. 4, pp. 247-320

Contributions to Journals: Articles

Digital Object Identifier: https://doi.org/10.1086/725363
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Disentangling the effects of obesity and high-fat diet on glucose homeostasis using a photoperiod induced obesity model implicates ectopic fat deposition as a key factor

2023

Yang, D. B., Gao, L., Liu, X. Y., Xu, Y. C., Hambly, C., Wang, D. H., Speakman, J. R.

Molecular Metabolism, vol. 73, 101724

Contributions to Journals: Articles

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The effects of graded levels of calorie restriction: XIX. Impact of graded calorie restriction on protein expression in the liver

2023

Wang, L., Derous, D., Huang, X., Mitchell, S. E., Douglas, A., Lusseau, D., Wang, Y., Speakman, J. R.

The Journals of Gerontology. Series A, Biological Sciences and Medical Sciences, vol. 78, no. 7, pp. 1125-1134

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Digital Object Identifier: https://doi.org/10.1093/gerona/glad017
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An Observational Case Series Measuring the Energy Expenditure of Elite Tennis Players During Competition and Training by Using Doubly Labeled Water

2023

Ellis, D. G., Speakman, J., Hambly, C., Morton, J. P., Close, G. L., Donovan, T. F.

International journal of sports physiology and performance, vol. 18, no. 5, pp. 547-552

Contributions to Journals: Articles

Digital Object Identifier: https://doi.org/10.1123/ijspp.2022-0297

Total daily energy expenditure has declined over the past three decades due to declining basal expenditure, not reduced activity expenditure

2023

Speakman, J. R., de Jong, J. M. A., Sinha, S., Westerterp, K. R., Yamada, Y., Sagayama, H., Ainslie, P. N., Anderson, L. J., Arab, L., Bedu-Addo, K., Blanc, S., Bonomi, A. G., Bovet, P., Brage, S., Buchowski, M. S., Butte, N. F., Camps, S. G. J. A., Cooper, J. A., Cooper, R., Das, S. K., Davies, P. S. W., Dugas, L. R., Ekelund, U., Entringer, S., Forrester, T., Fudge, B. W., Gillingham, M., Ghosh, S., Goris, A. H., Gurven, M., Halsey, L. G., Hambly, C., Haisma, H. H., Hoffman, D., Hu, S., Joosen, A. M., Kaplan, J. L., Katzmarzyk, P., Kraus, W. E., Kushner, R. F., Leonard, W. R., Löf, M., Martin, C. K., Matsiko, E., Medin, A. C., Meijer, E. P., Neuhouser, M. L., Nicklas, T. A., Ojiambo, R. M., Pietiläinen, K. H., Plange-Rhule, J., Plasqui, G., Prentice, R. L., Racette, S. B., Raichlen, D. A., Ravussin, E., Redman, L. M., Roberts, S. B., Rudolph, M. C., Sardinha, L. B., Schuit, A. J., Silva, A. M., Stice, E., Urlacher, S. S., Valenti, G., Van Etten, L. M., Van Mil, E. A., Wood, B. M., Yanovski, J. A., Yoshida, T., Zhang, X., Murphy-Alford, A. J., Loechl, C. U., Kurpad, A., Luke, A. H., Pontzer, H., Rodeheffer, M. S., Rood, J., Schoeller, D. A., Wong, W. W.

Nature Metabolism, vol. 5, no. 4, pp. 579-588

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Digital Object Identifier: https://doi.org/10.1038/s42255-023-00782-2
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Fur removal promotes an earlier expression of involution-related genes in mammary gland of lactating mice

2023

Krol, E., Turner, F., Derous, D., Mitchell, S. E., Martin, S., Douglas, A., Speakman, J.

Journal of Comparative Physiology. B, Biochemical, Systemic, and Environmental Physiology, pp. 171-192

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Digital Object Identifier: https://doi.org/10.1007/s00360-023-01474-9
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High dietary protein and fat contents exacerbate hepatic senescence and SASP in mice

2023

Nehme, J., Yang, D., Altulea, A., Varela-Eirin, M., Wang, L., Hu, S., Wu, Y., Togo, J., Niu, C., Speakman, J. R., Demaria, M.

FEBS Journal, vol. 290, no. 5, pp. 1340-1347

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Digital Object Identifier: https://doi.org/10.1111/febs.16292
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Large scale phenotype imputation and in vivo functional validation implicate ADAMTS14 as an adiposity gene

2023

Kentistou, K. A., Luan, J., Wittemans, L. B. L., Hambly, C., Klaric, L., Kutalik, Z., Speakman, J. R., Wareham, N. J., Kendall, T. J., Langenberg, C., Wilson, J. F., Joshi, P. K., Morton, N. M.

Nature Communications, vol. 14, 307

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Digital Object Identifier: https://doi.org/10.1038/s41467-022-35563-0
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The energy balance model of obesity: beyond calories in, calories out

2023

Hall, K. D., Farooqi, I. S., Friedman, J. M., Klein, S., Loos, R. J., Mangelsdorf, D. J., O'Rahilly, S., Ravussin, E., Redman, L. M., Ryan, D. H., Speakman, J. R., Tobias, D. K.

American Journal of Clinical Nutrition, vol. 115, no. 5, pp. 1243-1254

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Digital Object Identifier: https://doi.org/10.1093/ajcn/nqac031
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Variation in human water turnover associated with environmental and lifestyle factors

2022

Yamada, Y., Zhang, X., Henderson, M. E. T., Sagayama, H., Pontzer, H., Watanabe, D., Yoshida, T., Kimura, M., Ainslie, P. N., Andersen, L. F., Anderson, L. J., Arab, L., Baddou, I., Bedu-Addo, K., Blaak, E. E., Blanc, S., Bonomi, A. G., Bouten, C. V. C., Bovet, P., Buchowski, M. S., Butte, N. F., Camps, S. G., Close, G. L., Cooper, J. A., Cooper, R., Das, S. K., Dugas, L. R., Eaton, S., Ekelund, U., Entringer, S., Forrester, T., Fudge, B. W., Goris, A. H., Gurven, M., Halsey, L. G., Hambly, C., El Hamdouchi, A., Hoos, M. B., Hu, S., Joonas, N., Joosen, A. M., Katzmarzyk, P., Kempen, K. P., Kraus, W. E., Kriengsinyos, W., Kushner, R. F., Lambert, E. V., Leonard, W. R., Lessan, N., Speakman, J. R., International Atomic Energy Agency (IAEA) Doubly Labeled Water (DLW) Database Consortium

Science, vol. 378, no. 6622, pp. 909-915

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Digital Object Identifier: https://doi.org/10.1126/science.abm8668
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Focus on diet and exercise

2022

Speakman, J., Johnstone, A., Moholdt, T., Panda, S., Klein, S., Parker, B. L., Goodyear, L.

Contributions to Journals

Digital Object Identifier: https://doi.org/10.1016/j.cmet.2022.09.011

Higher than predicted resting energy expenditure and lower physical activity in healthy underweight Chinese adults

2022

Hu, S., Zhang, X., Stamatiou, M., Hambly, C., Huang, Y., Ma, J., Li, Y., Speakman, J. R.

Cell Metabolism, vol. 34, no. 10, pp. 1413-1415

Contributions to Journals: Letters

Digital Object Identifier: https://doi.org/10.1016/j.cmet.2022.05.012

Variability in energy expenditure is much greater in males than females

2022

Halsey, L. G., Careau, V., Pontzer, H., Ainslie, P. N., Andersen, L. F., Anderson, L. J., Arab, L., Baddou, I., Bedu-Addo, K., Blaak, E. E., Blanc, S., Bonomi, A. G., Bouten, C. V. C., Bovet, P., Buchowski, M. S., Butte, N. F., Camps, S. G. J. A., Close, G. L., Cooper, J. A., Das, S. K., Cooper, R., Dugas, L. R., Ekelund, U., Entringer, S., Forrester, T., Fudge, B. W., Goris, A. H., Gurven, M., Hambly, C., Hamdouchi, A. E., Hoos, M. B., Hu, S., Joonas, N., Joosen, A. M., Katzmarzyk, P., Kempen, K. P., Kimura, M., Kraus, W. E., Kushner, R. F., Lambert, E. V., Leonard, W. R., Lessan, N., Martin, C. K., Medin, A. C., Meijer, E. P., Morehen, J. C., Morton, J. P., Neuhouser, M. L., Nicklas, T. A., Ojiambo, R. M., Pietiläinen, K. H., Pitsiladis, Y. P., Plange-Rhule, J., Plasqui, G., Prentice, R. L., Rabinovich, R. A., Racette, S. B., Raichlen, D. A., Ravussin, E., Reynolds, R. M., Roberts, S. B., Schuit, A. J., Sjödin, A. M., Stice, E., Urlacher, S. S., Valenti, G., Van Etten, L. M., Van Mil, E. A., Wilson, G., Wood, B. M., Yanovski, J., Yoshida, T., Zhang, X., Murphy-Alford, A. J., Loechl, C. U., Luke, A. H., Rood, J., Sagayama, H., Schoeller, D. A., Westerterp, K. R., Wong, W. W., Yamada, Y., Speakman, J. R.

Journal of Human Evolution, vol. 171, 103229

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Digital Object Identifier: https://doi.org/10.1016/j.jhevol.2022.103229
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Effects of ambient temperatures between 5 and 35 °C on energy balance, body mass and body composition in mice

2022

Zhao, Z., Yang, R., Li, M., Bao, M., Huo, D., Cao, J., Speakman, J. R.

Molecular Metabolism, vol. 64, 101551

Contributions to Journals: Review articles

Digital Object Identifier: https://doi.org/10.1016/j.molmet.2022.101551
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The effects of graded levels of calorie restriction XVIII: tissue specific changes in cell size and number in response to calorie restriction

2022

Phillips, D., Mathers, H., Mitchell, S. E., Speakman, J. R.

The Journals of Gerontology. Series A, Biological Sciences and Medical Sciences, vol. 77, no. 10, pp. 1994-2001

Contributions to Journals: Articles

Digital Object Identifier: https://doi.org/10.1093/gerona/glac110
Open Access: http://aura.abdn.ac.uk/bitstreams/2ba7f3d5-2dca-4eec-b966-032d5c35a9f7/download

Human total, basal and activity energy expenditures are independent of ambient environmental temperature

2022

Zhang, X., Yamada, Y., Sagayama, H., Ainslie, P. N., Blaak, E. E., Buchowski, M. S., Close, G. L., Cooper, J. A., Das, S. K., Dugas, L. R., Gurven, M., El Hamdouchi, A., Hu, S., Joonas, N., Katzmarzyk, P., Kraus, W. E., Kushner, R. F., Leonard, W. R., Martin, C. K., Meijer, E. P., Neuhouser, M. L., Ojiambo, R. M., Pitsiladis, Y. P., Plasqui, G., Prentice, R. L., Racette, S. B., Ravussin, E., Redman, L. M., Reynolds, R. M., Roberts, S. B., Sardinha, L. B., Silva, A. M., Stice, E., Urlacher, S. S., Van Mil, E. A., Wood, B. M., Murphy-Alford, A. J., Loechl, C., Luke, A. H., Rood, J., Schoeller, D. A., Westerterp, K. R., Wong, W. W., Pontzer, H., Speakman, J. R., IAEA DLW Database Consortium

iScience, vol. 25, no. 8, 104682

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Obesity: an evolutionary context

2022

Speakman, J. R., Elmquist, J. K.

Life metabolism, vol. 1, no. 1, pp. 10-24

Contributions to Journals: Review articles

Digital Object Identifier: https://doi.org/10.1093/lifemeta/loac002
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The usage of different types of food outlets was not significantly associated with body mass index during the third COVID-19 national lockdown in the United Kingdom

2022

Albalawi, A., Hambly, C., Speakman, J. R.

Obesity Science & Practice, vol. 8, no. 4, pp. 411-422

Contributions to Journals: Articles

Digital Object Identifier: https://doi.org/10.1002/osp4.579
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Reply to G Taubes, MI Friedman, and V Torres-Carot et al.

2022

Hall, K. D., Farooqi, I. S., Friedman, J. M., Klein, S., Loos, R. J., Mangelsdorf, D. J., O’Rahilly, S., Ravussin, E., Redman, L. M., Ryan, D. H., Speakman, J. R., Tobias, D. K.

American Journal of Clinical Nutrition, vol. 116, no. 2, pp. 614-615

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Digital Object Identifier: https://doi.org/10.1093/ajcn/nqac163
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Interspecific coprophagia by wild red foxes: DNA metabarcoding reveals a potentially widespread form of commensalism among animals

2022

Navarro Waggershauser, C., Taberlet, P., Coissac, E., Kortland, K., Hambly, C., Lambin, X.

Ecology and Evolution, vol. 12, no. 7, e9029

Contributions to Journals: Articles

Digital Object Identifier: https://doi.org/10.1002/ece3.9029
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Consumption of takeaway and delivery meals is associated with increased BMI and percent fat among UK Biobank participants

2022

Speakman, J., Albalawi, A. A. A., Hambly, C.

The American Journal of Clinical Nutrition, vol. 116, no. 1, pp. 173-188

Contributions to Journals: Articles

Digital Object Identifier: https://doi.org/10.1093/ajcn/nqac078
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Accelerating animal energetics: high dive costs in a small seabird disrupt the dynamic body acceleration-energy expenditure relationship

2022

Ste-Marie, E., Grémillet, D., Fort, J., Patterson, A., Brisson-Curadeau, �., Clairbaux, M., Perret, S., Speakman, J. R., Elliott, K. H.

Journal of Experimental Biology, vol. 225, no. 12, jeb243252

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Digital Object Identifier: https://doi.org/10.1242/jeb.243252
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Energetics and Water Flux in the Subterranean Rodent Family Bathyergidae

2022

Hart, D. W., Bennett, N. C., Oosthuizen, M. K., Waterman, J. M., Hambly, C., Scantlebury, D. M.

Frontiers in Ecology and Evolution, vol. 10, 867350

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Digital Object Identifier: https://doi.org/10.3389/fevo.2022.867350
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Inhibitors of dihydroorotate dehydrogenase cooperate with molnupiravir and N4-hydroxycytidine to suppress SARS-CoV-2 replication

2022

Stegmann, K. M., Dickmanns, A., Heinen, N., Blaurock, C., Karrasch, T., Breithaupt, A., Klopfleisch, R., Uhlig, N., Eberlein, V., Issmail, L., Herrmann, S. T., Schreieck, A., Peelen, E., Kohlhof, H., Sadeghi, B., Riek, A., Speakman, J. R., Groß, U., Görlich, D., Vitt, D., Müller, T., Grunwald, T., Pfaender, S., Balkema-Buschmann, A., Dobbelstein, M.

iScience, vol. 25, no. 5, 104293

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Calorie restriction and calorie dilution have different impacts on body fat, metabolism, behavior, and hypothalamic gene expression

2022

Liu, X., Jin, Z., Summers, S., Derous, D., Li, M., Li, B., Li, L., Speakman, J.

Cell Reports, vol. 39, no. 7

Contributions to Journals: Articles

Digital Object Identifier: https://doi.org/10.1016/j.celrep.2022.110835
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Energy Expenditure of Female International Standard Soccer Players: A Doubly Labeled Water Investigation

2022

Morehen, J. C., Rosimus, C., Cavanagh, B. P., Hambly, C., Speakman, J. R., Elliott-Sale, K. J., Hannon, M. P., Morton, J. P.

Medicine and Science in Sports and Exercise, vol. 54, no. 5, pp. 769-779

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Online: https://e-space.mmu.ac.uk/631457/
Digital Object Identifier: https://doi.org/10.1249/MSS.0000000000002850
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Higher metabolic plasticity in temperate compared to tropical lizards suggests increased resilience to climate change

2022

Sun, B., Williams, C. M., Li, T., Speakman, J. R., Jin, Z., Lu, H., Luo, L., Du, W.

Ecological Monographs, vol. 92, no. 2, e1512

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Digital Object Identifier: https://doi.org/10.1002/ecm.1512
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Effects of dietary macronutrients on the hepatic transcriptome and serum metabolome in mice

2022

Wu, Y., Green, C. L., Wang, G., Yang, D., Li, L., Li, B., Wang, L., Li, M., Li, J., Xu, Y., Zhang, X., Niu, C., Hu, S., Togo, J., Mazidi, M., Derous, D., Douglas, A., Speakman, J.

Aging Cell, vol. 21, no. 4, e13585

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Effect of disrupted episodic memory on food consumption: no impact of neuronal loss of endophilin A1 on food intake and energy balance

2022

Togo, J., Yang, Y., Hu, S., Liu, J. J., Speakman, J. R.

Journal of genetics and genomics, vol. 49, no. 4, pp. 329-337

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Digital Object Identifier: https://doi.org/10.1016/j.jgg.2022.01.005
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Social associations in lactating dairy cows housed in a robotic milking system

2022

Marumo, J. L., Fisher, D. N., Lusseau, D., Mackie, M., Speakman, J. R., Hambly, C.

Applied Animal Behaviour Science, vol. 249, 105589

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Digital Object Identifier: https://doi.org/10.1016/j.applanim.2022.105589
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Increased Variation in Body Weight and Food Intake Is Related to Increased Dietary Fat but Not Increased Carbohydrate or Protein in Mice

2022

Wu, Y., Hu, S., Yang, D., Li, L., Li, B., Wang, L., Li, M., Wang, G., Li, J., Xu, Y., Zhang, X., Niu, C., Speakman, J. R.

Frontiers in Nutrition, vol. 9, 835536

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Digital Object Identifier: https://doi.org/10.3389/fnut.2022.1049766
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Body temperature is a more important modulator of lifespan than metabolic rate in two small mammals

2022

Zhao, Z., Cao, J., Niu, C., Bao, M., Xu, J., Huo, D., Liao, S., Liu, W., Speakman, J. R.

Nature Metabolism, vol. 4, no. 3, pp. 320-326

Contributions to Journals: Articles

Digital Object Identifier: https://doi.org/10.1038/s42255-022-00545-5
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Setting Ambient Temperature Conditions to Optimize Translation of Molecular Work from the Mouse to Human: The “Goldilocks Solution”

2022

Li, M., Speakman, J. R.

Brown Adipose Tissue. Guertin, D. A., Wolfrum, C. (eds.). 1st edition. HUMANA PRESS INC, pp. 235-250, 16 pages

Chapters in Books, Reports and Conference Proceedings: Chapters

Digital Object Identifier: https://doi.org/10.1007/978-1-0716-2087-8_15
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A Mesocosm Experiment in Ecological Physiology: The Modulation of Energy Budget in a Hibernating Marsupial under Chronic Caloric Restriction

2022

Nespolo, R. F., Fonturbel, F. E., Mejias, C., Contreras, R., Gutierrez, P., Oda, E., Sabat, P., Hambly, C., Speakman, J. R., Bozinovic, F.

Physiological and Biochemical Zoology, vol. 95, no. 1, pp. 66-81

Contributions to Journals: Articles

Digital Object Identifier: https://doi.org/10.1086/717760

A single nucleotide mutation in the dual-oxidase 2 (DUOX2) gene causes some of the panda's unique metabolic phenotypes

2022

Rudolf, A. M., Wu, Q., Li, L., Wang, J., Huang, Y., Togo, J., Liechti, C., Li, M., Niu, C., Nie, Y., Wei, F., Speakman, J. R.

National Science Review, vol. 9, no. 2, nwab125

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Digital Object Identifier: https://doi.org/10.1093/nsr/nwab125
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Influence of environmental factors and parity on milk yield dynamics in barn-housed dairy cattle

2022

Marumo, J. L., Lusseau, D., Speakman, J. R., Mackie, M., Hambly, C.

Journal of Dairy Science, vol. 105, no. 2, pp. 1225-1241

Contributions to Journals: Articles

Digital Object Identifier: https://doi.org/10.3168/jds.2021-20698
Open Access: http://aura.abdn.ac.uk/bitstreams/65a1d21e-7872-452d-898a-5764b8554857/download
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The roles of different macronutrients in regulation of appetite, energy intake and adiposity

2022

Speakman, J. R.

Current Opinion in Endocrine and Metabolic Research, vol. 22, 100297

Contributions to Journals: Review articles

Digital Object Identifier: https://doi.org/10.1016/j.coemr.2021.100297
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Total energy expenditure is repeatable in adults but not associated with short-term changes in body composition

2022

Rimbach, R., Yamada, Y., Sagayama, H., Ainslie, P. N., Anderson, L. F., Anderson, L. J., Arab, L., Baddou, I., Bedu-Addo, K., Blaak, E. E., Blanc, S., Bonomi, A. G., Bouten, C. V., Bovet, P., Buchowski, M. S., Butte, N. F., Camps, S. G., Close, G. L., Cooper, J. A., Das, S. K., Dugas, L. R., Ekelund, U., Entringer, S., Forrester, T., Fudge, B. W., Goris, A. H., Gurven, M., Hambly, C., El Hamdouchi, A., Hoos, M. B., Hu, S., Joonas, N., Joosen, A. M., Katzmarzyk, P., Kempen, K. P., Kimura, M., Kraus, W. E., Kushner, R. F., Lambert, E. V., Leonard, W. R., Lessan, N., Martin, C. K., Medin, A. C., Meijer, E. P., Morehen, J. C., Morton, J. P., Neuhouser, M. L., Nicklas, T. A., Ojiambo, R. M., Pietiläinen, K. H., Speakman, J., The IAEA DLW Database Consortium, Pitsiladis, Y. P., Plange-Rhule, J., Plasqui, G., Prentice, R. L., Rabinovich, R. A., Racette, S. B., Raichlen, D. A., Ravussin, E., Reynolds, R. M., Roberts, S. B., Schuit, A. J., Sjodin, A. M., Stice, E., Urlacher, S. S., Valenti, G., Van Etten, L. M., Van Mil, E. A., Wells, J. C., Wilson, G., Wood, B. M., Yanovski, J., Yoshida, T., Zhang, X., Murphy-Alford, A. J., Loechl, C. U., Luke, A., Rood, J., Schoeller, D. A., Westerterp, K. R., Wong, W. W., Pontzer, H.

Nature Communications, vol. 13, no. 1, 99

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Digital Object Identifier: https://doi.org/10.1038/s41467-021-27246-z
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Energy Expenditure of a Male and Female Tennis Player during Association of Tennis Professionals/Women's Tennis Association and Grand Slam Events Measured by Doubly Labeled Water

2021

Ellis, D. G., Speakman, J., Hambly, C., Morton, J. P., Close, G. L., Lewindon, D., Donovan, T. F.

Medicine and Science in Sports and Exercise, vol. 53, no. 12, pp. 2628-2634

Contributions to Journals: Articles

Digital Object Identifier: https://doi.org/10.1249/MSS.0000000000002745
Additional Links: View publication in Scopus; Link to AM in Liverpool John Moores repository

Brown adipose tissue is the key depot for glucose clearance in microbiota depleted mice

2021

Li, M., Li, L., Li, B., Hambly, C., Wang, G., Wu, Y., Jin, Z., Wang, A., Niu, C., Wolfrum, C., Speakman, J. R.

Nature Communications, vol. 12, no. 1, 4725

Contributions to Journals: Articles

Digital Object Identifier: https://doi.org/10.1038/s41467-021-24659-8
Open Access: http://aura.abdn.ac.uk/bitstreams/1c4edfd3-371d-4f4a-b7ff-44f8234007a1/download
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Physical activity and fat-free mass during growth and in later life

2021

Westerterp, K. R., Yamada, Y., Sagayama, H., Ainslie, P. N., Andersen, L. F., Anderson, L. J., Arab, L., Baddou, I., Bedu-Addo, K., Blaak, E. E., Blanc, S., Bonomi, A. G., Bouten, C. V., Bovet, P., Buchowski, M. S., Butte, N. F., Camps, S. G., Close, G. L., Cooper, J. A., Das, S. K., Cooper, R., Dugas, L. R., Ekelund, U., Entringer, S., Forrester, T., Fudge, B. W., Goris, A. H., Gurven, M., Hambly, C., El Hamdouchi, A. E., Hoos, M. B., Hu, S., Joonas, N., Joosen, A. M., Katzmarzyk, P., Kempen, K. P., Kimura, M., Kraus, W. E., Kushner, R. F., Lambert, E. V., Leonard, W. R., Lessan, N., Martin, C. K., Medin, A. C., Meijer, E. P., Morehen, J. C., Morton, J. P., Neuhouser, M. L., Zhang, X., Speakman, J. R., International Atomic Energy Agency Doubly Labeled Water database group

American Journal of Clinical Nutrition, vol. 114, no. 5, pp. 1583-1589

Contributions to Journals: Articles

Digital Object Identifier: https://doi.org/10.1093/ajcn/nqab260
Open Access: http://aura.abdn.ac.uk/bitstreams/5b684abe-56ae-4f22-ad23-d3b058e5436d/download
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Energy compensation and adiposity in humans

2021

Careau, V., Halsey, L. G., Pontzer, H., Ainslie, P. N., Andersen, L. F., Anderson, L. J., Arab, L., Baddou, I., Bedu-Addo, K., Blaak, E. E., Blanc, S., Bonomi, A. G., Bouten, C. V. C., Buchowski, M. S., Butte, N. F., Camps, S. G. J. A., Close, G. L., Cooper, J. A., Das, S. K., Cooper, R., Dugas, L. R., Eaton, S. D., Ekelund, U., Entringer, S., Forrester, T., Fudge, B. W., Goris, A. H., Gurven, M., Hambly, C., El Hamdouchi, A., Hoos, M. B., Hu, S., Joonas, N., Joosen, A. M., Katzmarzyk, P., Kempen, K. P., Kimura, M., Kraus, W. E., Kushner, R. F., Lambert, E., Leonard, W. R., Lessan, N., Martin, C. K., Medin, A. C., Meijer, E. P., Morehen, J. C., Morton, J. P., Neuhouser, M. L., Nicklas, T. A., Ojiambo, R. M., Pietilainen, K. H., Pitsiladis, Y. P., Plange-Rhule, J., Plasqui, G., Prentice, R. L., Rabinovich, R. A., Racette, S. B., Raichlen, D. A., Ravussin, E., Reilly, J. J., Reynolds, R. M., Roberts, S. B., Schuit, A. J., Sjodin, A. M., Stice, E., Urlacher, S. S., Valenti, G., Van Etten, L. M., Van Mil, E. A., Wells, J. C. K., Wilson, G., Wood, B. M., Yanovski, J., Yoshida, T., Zhang, X., Murphy-Alford, A. J., Loechl, C. U., Luke, A. H., Rood, J., Sagayama, H., Schoeller, D. A., Wong, W. W., Yamada, Y., Speakman, J. R.

Current Biology, vol. 31, no. 20, pp. 4659-4666

Contributions to Journals: Articles

Digital Object Identifier: https://doi.org/10.1016/j.cub.2021.08.016
Open Access: http://aura.abdn.ac.uk/bitstreams/3d6b99be-948d-454c-8231-159582d04e41/download

Determinants of heart rate in Svalbard reindeer reveal mechanisms of seasonal energy management

2021

Trondrud, L. M., Pigeon, G., Albon, S., Arnold, W., Evans, A. L., Irvine, R. J., Król, E., Ropstad, E., Stien, A., Veiberg, V., Speakman, J. R., Loe, L. E.

Philosophical Transactions of the Royal Society B: Biological Sciences, vol. 376, no. 1831, 20200215

Contributions to Journals: Articles

Digital Object Identifier: https://doi.org/10.1098/rstb.2020.0215
Open Access: http://aura.abdn.ac.uk/bitstreams/c2f286b1-799c-47b3-a430-452b10df9002/download
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Daily energy expenditure through the human life course

2021

Pontzer, H., Yamada, Y., Sagayama, H., Ainslie, P. N., Andersen, L. F., Anderson, L. J., Arab, L., Baddou, I., Bedu-Addo, K., Blaak, E. E., Blanc, S., Bonomi, A. G., Bouten, C. V., Bovet, P., Buchowski, M. S., Butte, N. F., Camps, S. G., Close, G. L., Cooper, J. A., Cooper, R., Das, S. K., Dugas, L. R., Ekelund, U., Entringer, S., Forrester, T., Fudge, B. W., Goris, A. H., Gurven, M., Hambly, C., El Hamdouchi, A., Hoos, M. B., Hu, S., Joonas, N., Joosen, A. M., Katzmarzyk, P., Kempen, K. P., Kimura, M., Kraus, W. E., Kushner, R. F., Lambert, E. V., Leonard, W. R., Lessan, N., Martin, C., Medin, A. C., Meijer, E. P., Morehen, J. C., Morton, J. P., Neuhouser, M. L., Zhang, X., Speakman, J. R., IAEA DLW Database Consortium, Luke, A. H., Rood, J., Schoeller, D. A., Westerterp, K. R., Wong, W. W.

Science, vol. 373, no. 6556, pp. 808-812

Contributions to Journals: Articles

Digital Object Identifier: https://doi.org/10.1126/science.abe5017
Additional Links: View publication in Scopus; Accepted Manuscript in UCL repository

The effects of graded calorie restriction XVII: Multitissue metabolomics reveals synthesis of carnitine and NAD, and tRNA charging as key pathways

2021

García-Flores, L. A., Green, C. L., Mitchell, S. E., Promislow, D. E., Lusseau, D., Douglas, A., Speakman, J. R.

Proceedings of the National Academy of Sciences of the United States of America, vol. 118, no. 31, e2101977118

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Digital Object Identifier: https://doi.org/10.1073/pnas.2101977118
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Surviving winter on the Qinghai-Tibetan Plateau: Pikas suppress energy demands and exploit yak feces to survive winter

2021

Speakman, J. R., Chi, Q., Ołdakowski, �., Fu, H., Fletcher, Q. E., Hambly, C., Togo, J., Liu, X., Piertney, S. B., Wang, X., Zhang, L., Redman, P., Wang, L., Tang, G., Li, Y., Cui, J., Thomson, P. J., Wang, Z., Glover, P., Robertson, O. C., Zhang, Y., Wang, D.

Proceedings of the National Academy of Sciences of the United States of America, vol. 118, no. 30, e2100707118

Contributions to Journals: Articles

Digital Object Identifier: https://doi.org/10.1073/pnas.2100707118
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Fat storage influences fasting endurance more than body size in an ungulate

2021

Trondrud, L. M., Pigeon, G., Król, E., Albon, S., Evans, A. L., Arnold, W., Hambly, C., Irvine, R. J., Ropstad, E., Stien, A., Veiberg, V., Speakman, J. R., Loe, L. E.

Functional Ecology, vol. 35, no. 7, pp. 1470-1480

Contributions to Journals: Articles

Digital Object Identifier: https://doi.org/10.1111/1365-2435.13816
Open Access: http://aura.abdn.ac.uk/bitstreams/f2e176ed-9303-4289-81f8-c89011d8f5cf/download

The impact of the novel coronavirus movement restrictions in the United Kingdom on food outlet usage and body mass index

2021

Albalawi, A., Hambly, C., Speakman, J. R.

Obesity Science & Practice, vol. 7, no. 3, pp. 302-306

Contributions to Journals: Articles

Digital Object Identifier: https://doi.org/10.1002/osp4.477
Open Access: http://aura.abdn.ac.uk/bitstreams/9345c289-7454-467f-9c0a-5fa6defa2716/download

Depletion of the gut microbiota differentially affects the impact of whey protein on high-fat diet-induced obesity and intestinal permeability

2021

Boscaini, S., Cabrera-Rubio, R., Golubeva, A., Nychyk, O., Fülling, C., Speakman, J. R., Cotter, P. D., Cryan, J. F., Nilaweera, K. N.

Physiological reports, vol. 9, no. 11, e14867

Contributions to Journals: Articles

Digital Object Identifier: https://doi.org/10.14814/phy2.14867
Open Access: http://aura.abdn.ac.uk/bitstreams/61d3b4f0-c1bb-405f-b4d5-aa7c145ecdb4/download
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Adaptive immune response and resting metabolism are unaffected by manipulation of flight intensity, but negatively related to each other

2021

Bryła, A., Bury, A., Niedojadło, J., Speakman, J. R., Sadowska, E. T., Cichoń, M., Bauchinger, U.

Journal of Avian Biology, vol. 52, no. 5, e02764

Contributions to Journals: Articles

Digital Object Identifier: https://doi.org/10.1111/jav.02764

The Assessment of Daily Energy Expenditure of Commercial Saturation Divers Using Doubly Labelled Water

2021

Deb, S. K., Dolan, E., Hambly, C., Speakman, J. R., Eftedal, O., Zariwala, M. G., Eftedal, I.

Frontiers in Physiology, vol. 12, 687605

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Digital Object Identifier: https://doi.org/10.3389/fphys.2021.687605
Open Access: http://aura.abdn.ac.uk/bitstreams/5f2d280b-f0a1-483f-b84d-e3a32f0e6267/download

Protein quality and quantity influence the effect of dietary fat on weight gain and tissue partitioning via host-microbiota changes

2021

Nychyk, O., Barton, W., Rudolf, A. M., Boscaini, S., Walsh, A., Bastiaanssen, T. F., Giblin, L., Cormican, P., Chen, L., Piotrowicz, Y., Derous, D., Fanning, �., Yin, X., Grant, J., Melgar, S., Brennan, L., Mitchell, S. E., Cryan, J. F., Wang, J., Cotter, P. D., Speakman, J. R., Nilaweera, K. N.

Cell Reports, vol. 35, no. 6, 109093

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Digital Object Identifier: https://doi.org/10.1016/j.celrep.2021.109093
Open Access: http://aura.abdn.ac.uk/bitstreams/abc30b6b-92fe-4ecd-8dbf-bd0ac8c8b965/download

Carbohydrates, insulin, and obesity

2021

Speakman, J. R., Hall, K. D.

Science, vol. 372, no. 6542, pp. 577-578

Contributions to Journals: Comments and Debates

Digital Object Identifier: https://doi.org/10.1126/science.aav0448

Very-low-protein diets lead to reduced food intake and weight loss, linked to inhibition of hypothalamic mTOR signaling, in mice

2021

Wu, Y., Li, B., Li, L., Mitchell, S. E., Green, C. L., D'Agostino, G., Wang, G., Wang, L., Li, M., Li, J., Niu, C., Jin, Z., Wang, A., Zheng, Y., Douglas, A., Speakman, J. R.

Cell Metabolism, vol. 33, no. 5, pp. P888-904.E6

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Digital Object Identifier: https://doi.org/10.1016/j.cmet.2021.01.017

Comparison of total and activity energy expenditure estimates from physical activity questionnaires and doubly labelled water: a systematic review and meta-analysis

2021

Sharifzadeh, M., Bagheri, M., Speakman, J. R., Djafarian, K.

British Journal of Nutrition, vol. 125, no. 9, pp. 983–997

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Digital Object Identifier: https://doi.org/10.1017/S0007114520003049
Open Access: http://aura.abdn.ac.uk/bitstreams/78de7a2f-d02c-4c4b-b936-204f4bdacb71/download; http://aura.abdn.ac.uk/bitstreams/f5c61df8-fe43-4db7-8053-f96330f55a14/download
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Validating accelerometry-derived proxies of energy expenditure using the doubly-labelled water method in the smallest penguin species

2021

Sutton, G. J., Botha, J. A., Speakman, J. R., Arnould, J. P. Y.

Open Biology, vol. 10, no. 4, bio055475

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Digital Object Identifier: https://doi.org/10.1242/bio.055475
Open Access: http://aura.abdn.ac.uk/bitstreams/986b9af7-a8af-4e35-bf6f-a6753c085ae7/download
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The effects of graded levels of calorie restriction: XVI. Metabolomic changes in the cerebellum indicate activation of hypothalamocerebellar connections driven by hunger responses

2021

Green, C. L., Mitchell, S. E., Derous, D., García-Flores, L. A., Wang, Y., Chen, L., Han, J. J., Promislow, D. E. L., Lusseau, D., Douglas, A., Speakman, J. R.

The Journals of Gerontology. Series A, Biological Sciences and Medical Sciences, vol. 76, no. 4, pp. 601-610

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Online: https://osf.io/4wfpa/
Digital Object Identifier: https://doi.org/10.1093/gerona/glaa261
Open Access: http://aura.abdn.ac.uk/bitstreams/4680af64-f09f-4825-aaad-9a210cff7162/download

Beneficial impact of exercise on bone mass in individuals under calorie restriction: a systematic review and Meta-analysis of randomized clinical trials

2021

Yarizadeh, H., Asadi, S., Baharlooi, H., Setayesh, L., Kakavandi, N. R., Hambly, C., Djafarian, K., Mirzaei, K.

Critical reviews in food science and nutrition, vol. 61, no. 4, pp. 553-565

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Digital Object Identifier: https://doi.org/10.1080/10408398.2020.1739620
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A standard calculation methodology for human doubly labeled water studies

2021

Speakman, J. R., Yamada, Y., Sagayama, H., Berman, E. S. F., Ainslie, P. N., Andersen, L. F., Anderson, L. J., Arab, L., Baddou, I., Bedu-Addo, K., Blaak, E. E., Blanc, S., Bonomi, A. G., Bouten, C. V. C., Bovet, P., Buchowski, M. S., Butte, N. F., Camps, S. G. J. A., Close, G. L., Cooper, J. A., Creasy, S. A., Das, S. K., Cooper, R., Dugas, L. R., Ebbeling, C. B., Ekelund, U., Entringer, S., Forrester, T., Fudge, B. W., Goris, A. H., Gurven, M., Hambly, C., El Hamdouchi, A., Hoos, M. B., Hu, S., Joonas, N., Joosen, A. M., Katzmarzyk, P., Kempen, K. P., Kimura, M., Kraus, W. E., Kushner, R. F., Lambert, E. V., Leonard, W. R., Lessan, N., Ludwig, D. S., Martin, C. K., Medin, A. C., Meijer, E. P., Morehen, J. C., Morton, J. P., Neuhouser, M. L., Nicklas, T. A., Ojiambo, R. M., Pietiläinen, K. H., Pitsiladis, Y. P., Plange-Rhule, J., Plasqui, G., Prentice, R. L., Rabinovich, R. A., Racette, S. B., Raichlen, D. A., Ravussin, E., Reynolds, R. M., Roberts, S. B., Schuit, A. J., Sjödin, A. M., Stice, E., Urlacher, S. S., Valenti, G., Van Etten, L. M., Van Mil, E. A., Wells, J. C., Wilson, G., Wood, B. M., Yanovski, J., Yoshida, T., Zhang, X., Murphy-Alford, A. J., Loechl, C. U., Melanson, E. L., Luke, A. H., Pontzer, H., Rood, J., Schoeller, D. A., Westerterp, K. R., Wong, W. W., IAEA DLW database group

Cell reports. Medicine, vol. 2, no. 2, 100203

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Digital Object Identifier: https://doi.org/10.1016/j.xcrm.2021.100203
Open Access: http://aura.abdn.ac.uk/bitstreams/30a0fce3-be76-42c7-bde7-278f04fb43a5/download
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Daily energy expenditure and water turnover in two breeds of laying hens kept in floor housing

2021

Riek, A., Petow, S., Speakman, J. R., Schrader, L.

Animal , vol. 15, no. 1, 100047

Contributions to Journals: Articles

Digital Object Identifier: https://doi.org/10.1016/j.animal.2020.100047
Open Access: http://aura.abdn.ac.uk/bitstreams/ab7e32c9-f6c6-422d-b6d0-26df1ba0e778/download

Effects of dietary macronutrients and body composition on glucose homeostasis in mice

2021

Hu, S., Togo, J., Wang, L., Wu, Y., Yang, D., Xu, Y., Li, L., Li, B., Li, M., Li, J., Wang, G., Zhang, X., Niu, C., Mazidi, M., Douglas, A., Speakman, J. R.

National Science Review, vol. 8, no. 1, nwaa177

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Digital Object Identifier: https://doi.org/10.1093/nsr/nwaa177
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