Dr James Sinclair
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Dr James Sinclair
Senior Research Fellow
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Page 1 of 2 Results 1 to 10 of 11
Cellular Models of Aggregation-Dependent Template-Directed Proteolysis to Characterize Tau Aggregation Inhibitors for Treatment of Alzheimer's Disease
The Journal of Biological Chemistry, vol. 290, no. 17, pp. 10862-10875Contributions to Journals: ArticlesMaking thiosulfate-disubstituted-amino-optionally substituted-phenyl-imino-optionally substituted-cyclohexadienylidene-N,N-disubstituted-ammoniums comprises carrying out nitrosyl reduction, thiosulfonic acid formation and oxidative coupling
Patents: PatentsNew phenothiazine diaminium compounds are tau protein aggregation inhibitors, useful to treat e.g. Alzheimer's disease, Pick's disease, progressive supranuclear palsy, frontotemporal dementia and frontotemporal lobar degeneration syndromes
Patents: Patents3,7-diamino-10H-phenothiazine salts and their use: WO2007110627
Patents: PatentsMethods of chemical synthesis and purification of diaminophenothiazinium compounds including methylthioninium chloride (MTC): methods of treatment of a tauopathy condition comprising the use of thioninium compounds
Patents: PatentsMethods of synthesis and/or purification of diaminophenothiazinium compounds
Patents: PatentsCo-operative stabilisation of a 15-component nanostructure
Journal of Chemical Research, vol. 2007, no. 5, pp. 287-290Contributions to Journals: Articles- [ONLINE] DOI: https://doi.org/10.3184/030823407X215636
New tetrahydro-1,2,4,5-tetrazinan-3-ones and oxoverdazyl free radicals
Journal of Chemical Research, vol. 8, no. 8, pp. 515-520Contributions to Journals: Articles- [ONLINE] DOI: https://doi.org/10.3184/030823406778256478
- [ONLINE] View publication in Scopus
The first double helical coordination network with shared copper atoms
Journal of Molecular Structure, vol. 784, no. 1-3, pp. 269-271Contributions to Journals: Articles- [ONLINE] DOI: https://doi.org/10.1016/j.molstruc.2005.06.039
- [ONLINE] View publication in Scopus
Methods of chemical synthesis and purification of diaminophenothiazinium compounds including methylthioninium chloride (MTC)
Patents: Patents