Professor Graeme MacLennan
Health Services Research Unit
2nd Floor Health Sciences Building
I am currently Professor of Medical Statistics and the Director of the Centre for Health Care Randomised Trials (CHaRT) which is the Clinical Trials Unit embedded within the Health Services Research Unit. My overarching research interest is in designing fair tests of health care treatments and policies, with a specifc interest in evaluating surgical and complex interventions. I'm also interested in improving the design, conduct, and analysis and reporting of clinical trials through the development and application of methodological research to clinical trials from CHaRT.
My undergrad degree is in Mathematics from the University of Aberdeen, graduating in 1997. After a year training as a Mathematics teacher I joined the Unit in September 1998 as a statistician. I studied part-time for an MSc in Applied Statistics with Sheffield Hallam University, graduating in 2004. In 2008 I was appointed Senior Statistican, and in 2016 was I Interim Programme Director for the Health Care Assessment Programme, until being appointment as CHaRT Director in April 2017.
- BSc Mathematics1997 - University of Aberdeen
- MSc Applied Statistics2004 - Sheffield Hallam University
The application of statistical methods to clinical trials. Recent example is JCE paper available here on using instrumental variables in a surgery trial to address non-compliance. Collaborators were Jonathan Cook (Oxford), Tom Palmer (Lancaster), and Richard Emesley (Manchester).
Research on making trials more efficient, collaborating with Trial Forge.
A complete list of the CHaRT RCT portolio is available by clicking here
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A multicentre open label randomised clinical trial using exhaled nitric oxide in addition to standard care to reduce asthma attacks in childrenEfficacy and Mechanism EvaluationContributions to Journals: Articles
The IDENTIFY Study: The Investigation and Detection of Urological Neoplasia in Patients Referred with Suspected Urinary Tract Cancer; A multicentre observational studyBJU International, vol. 128, no. 4, pp. 440-450Contributions to Journals: Articles
Why trials lose participants: a multi-trial investigation of participants’ perspectives using the theoretical domains frameworkJournal of Clinical Epidemiology, vol. 137, pp. P1-13Contributions to Journals: Articles
Selective Caries Removal in Permanent Teeth (SCRiPT) for the treatment of deep carious lesions: a randomised controlled clinical trial in primary careBMC Oral Health, vol. 21, 336Contributions to Journals: Articles
Have you had bleeding from your gums?: Self-report to Identify giNGival inflammation (The SING diagnostic accuracy and diagnostic model development study)Journal of Journal of Clinical Periodontology, vol. 48, no. 7, pp. 919-928Contributions to Journals: Articles
Shockwave Lithotripsy Versus Ureteroscopic Treatment as Therapeutic Interventions for Stones of the Ureter (TISU): A Multicentre Randomised Controlled Non-inferiority TrialEuropean Urology, vol. 80, no. 1, pp. 46-54Contributions to Journals: Articles
The arabin pessary to prevent preterm birth in women with a twin pregnancy and a short cervix: The STOPPIT 2 RCTNIHR Health Technology Assessment programme. 94 pagesBooks and Reports: Other Reports
Outcomes of a non-inferiority randomised controlled trial of surgery for men with urodynamic stress incontinence after prostate surgery (MASTER)European Urology, vol. 79, no. 6, pp. 812-823Contributions to Journals: Articles
Tibial nerve stimulation compared with sham to reduce incontinence in care home residents: ELECTRIC RCTHealth technology assessment (Winchester, England), vol. 25, no. 41, pp. 1-109Contributions to Journals: Articles
Primary trabeculectomy for advanced glaucoma: pragmatic multicentre randomised controlled trial (TAGS)BMJ, vol. 373, n1014Contributions to Journals: Articles