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Professor Graeme MacLennan
Professor Graeme MacLennan

Professor Graeme MacLennan

Director (CHaRT)

About

Health Services Research Unit
2nd Floor Health Sciences Building
Foresterhill
Aberdeen
AB25 2ZD

ORCiD

Biography

I am currently Professor of Medical Statistics and the Director of the Centre for Health Care Randomised Trials (CHaRT) which is the Clinical Trials Unit embedded within the Health Services Research Unit. My overarching research interest is in designing fair tests of health care treatments and policies, with a specifc interest in evaluating surgical and complex interventions. I'm also interested in improving the design, conduct, and analysis and reporting of clinical trials through the development and application of methodological research to clinical trials from CHaRT. 

My undergrad degree is in Mathematics from the University of Aberdeen, graduating in 1997. After a year training as a Mathematics teacher I joined the Unit in September 1998 as a statistician. I studied part-time for an MSc in Applied Statistics with Sheffield Hallam University, graduating in 2004. In 2008 I was appointed Senior Statistican, and in 2016 was I Interim Programme Director for the Health Care Assessment Programme, until being appointment as CHaRT Director in April 2017.  

Qualifications

  • BSc Mathematics 
    1997 - University of Aberdeen 
  • MSc Applied Statistics 
    2004 - Sheffield Hallam University 
Research

Research Overview

The application of statistical methods to clinical trials. Recent example is JCE paper available here on using instrumental variables in a surgery trial to address non-compliance. Collaborators were Jonathan Cook (Oxford), Tom Palmer (Lancaster), and Richard Emesley (Manchester). 

Research on making trials more efficient, collaborating with Trial Forge. 

Current Research

A complete list of the CHaRT RCT portolio is available by clicking here

Teaching

Teaching Responsibilities

I teach on our MPH course module PU5031: EVIDENCE-BASED HEALTH.

Publications

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  • The Achieving Self-directed Integrated Cancer Aftercare Intervention for Detection of Recurrent and Second Primary Melanoma in Survivors of Melanoma: Pilot Randomized Controlled Trial

    Murchie, P., Constable, L., Hall, S., Brant, W., Allan, J., Johnston, M., Masthoff, J., Lee, A., Treweek, S., Ayansina, D., Proby, C., Rahman, K., Walter, F., Burrows, N., Durrani, A., Maclennan, G.
    JMIR cancer, vol. 8, no. 3, e37539
    Contributions to Journals: Articles

  • Cost utility analysis of shockwave lithotripsy versus ureteroscopic stone treatment in adults

    Kilonzo, M. M., Dasgupta, R., Thomas, R., Aucott, L., MacLennan, S., Lam, T., Anson, K., Cameron, S., Starr, K., Burgess, N., Keeley, F. X., Clark, C. T., N’Dow, J., MacLennan, G., McClinton, S.
    BJU International
    Contributions to Journals: Articles

  • Randomised controlled trial comparing the clinical and cost-effectiveness of various washout policies versus no washout policy in preventing catheter associated complications in adults living with long-term catheters: study protocol for the CATHETER II study

    Abdel-fattah, M., Johnson, D., Constable, L., Thomas, R., Cotton, S., Tripathee, S., Cooper, D., Boran, S., Dimitropoulos, K., Evans, S., Granitsiotis, P., Hashim, H., Kilonzo, M., Larcombe, J., Little, P., MacLennan, S., Murchie, P., Myint, P., N’Dow, J., Norrie, J., Omar, M. I., Paterson, C., Scotland, G., Thiruchelvam, N., MacLennan, G.
    Trials, vol. 23, no. 1, 630
    Contributions to Journals: Articles

  • Male synthetic sling or artificial urinary sphincter (AUS) for men with urodynamic stress incontinenceafter prostate surgery: the MASTER non-inferiority randomised controlled trial

    Constable, L., Abrams, P., Cooper, D., Kilonzo, M., Cotterill, N., Harding, C. K., Drake, M. J., Pardoe, M. N., McDonald, A., Smith, R., Norrie, J., McCormack, K., Ramsay, C., Uren, A., Mundy, T., Glazener, C., MacLennan, G.
    Health Technology Assessment, vol. 26, no. 36
    Contributions to Journals: Articles

  • Cost-effectiveness of primary surgical versus primary medical management in the treatment of patients presenting with advanced glaucoma

    Kernohan, A., Homer, T., Shabaninejad, H., King, A. J., Hudson, J., Fernie, G., Azuara-Blanco, A., Burr, J., Sparrow, J. M., Garway-Heath, D., Barton, K., Norrie, J., Maclennan, G., Vale, L.
    British Journal of Ophthalmology
    Contributions to Journals: Articles

  • Effectiveness and cost-effectiveness of text messages with or without endowment incentives for weight management in men with obesity (Game of Stones): study protocol for a randomised controlled trial

    Macaulay, L., O’Dolan, C., Avenell, A., Carroll, P., Cotton, S., Dombrowski, S., Elders, A., Goulao, B., Gray, C., Harris, F. M., Hunt, K., Kee, F., MacLennan, G., McDonald, M. D., McKinley, M., Skinner, R., Torrens, C., Tod, M., Turner, K., van der Pol, M., Hoddinott, P.
    Trials, vol. 23, no. 1, 582
    Contributions to Journals: Articles

  • Remotely delivered cognitive behavioural and personalised exercise interventions for fatigue severity and impact in inflammatory rheumatic diseases: a multi-centre randomised controlled parallel open-label group trial (LIFT)

    Bachmair, E., Martin, K., Aucott, L., Dhaun, N., Dures, E., Emsley, R., Gray, S. R., Kidd, E., Kumar, V., Lovell, K., MacLennan, G., McNamee, P., Norrie, J., Paul, L., Packham, J., Ralston, S. H., Siebert, S., Wearden, A., LIFT study group, Macfarlane, G., Basu, N.
    The Lancet Rheumatology
    Contributions to Journals: Articles

  • Developing a Diagnostic Multivariable Prediction Model for Urinary Tract Cancer in Patients Referred with Haematuria: results from the IDENTIFY Collaborative Study

    Khadhouri, S., Gallagher, K. M., MacKenzie, K. R., Shah, T. T., Gao, C., Moore, S., Zimmermann, E. F., Edison, E., Jefferies, M., Nambiar, A., Anbarasan, T., Mannas, M. P., Lee, T., Marra, G., Gómez Rivas, J., Marcq, G., Assmus, M. A., Uçar, T., Claps, F., Boltri, M., La Montagna, G., Burnhope, T., Nkwam, N., Austin, T., Boxall, N. E., Downey, A. P., Sukhu, T. A., Antón-Juanilla, M., Rai, S., Chin, Y., Moore, M., Drake, T., Green, J. S., Goulao, B., MacLennan, G., Nielsen, M., McGrath, J. S., Kasivisvanathan, V., Chaudry, A., Sharma, A., Bennett, A., MacKay, A., Gordon, D., Jones, J., Brown, K., Osei-Bonsu, P. K., Smith, P., Ellis, R., Hawkins, R., Khan, S., The IDENTIFY Study Group
    European Urology Focus
    Contributions to Journals: Articles

  • Reducing asthma attacks in children using exhaled nitric oxide (RAACENO) as a biomarker to inform treatment strategy: a multicentre, parallel, randomised, controlled, phase 3 trial

    Turner, S., Cotton, S., Wood, J., Bell, V., Raja, E. A., Scott, N., Morgan, H., Lawrie, L., Emele, D., Kennedy, C., Scotland, G., Fielding, S., MacLennan, G., Norrie, J., Forrest, M., Gaillard, E. A., de Jongste, J. C., Pijnenburg, M. W., Thomas, M., Price, D.
    The Lancet. Respiratory medicine, vol. 10, no. 6, pp. 584-592
    Contributions to Journals: Articles

  • Treatment guided by fractional exhaled nitric oxide in addition to standard care in 6- to 15-year-olds with asthma: the RAACENO RCT

    Turner, S., Cotton, S., Wood, J., Bell, V., Raja, E. A., Scott, N., Morgan, H., Lawrie, L., Emele, D., Kennedy, C., Scotland, G., Fielding, S., MacLennan, G., Norrie, J., Forrest, M., Gaillard, E. A., de Jongeste, J., Pijnenburg, M. W., Thomas, M., Price, D.
    Efficacy and Mechanism Evaluation, vol. 9, no. 4
    Contributions to Journals: Articles
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