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Professor Graeme MacLennan
Professor Graeme MacLennan

Professor Graeme MacLennan

Director (CHaRT)

About

Health Services Research Unit
2nd Floor Health Sciences Building
Foresterhill
Aberdeen
AB25 2ZD

ORCiD

Biography

I am currently Professor of Medical Statistics and the Director of the Centre for Health Care Randomised Trials (CHaRT) which is the Clinical Trials Unit embedded within the Health Services Research Unit. My overarching research interest is in designing fair tests of health care treatments and policies, with a specifc interest in evaluating surgical and complex interventions. I'm also interested in improving the design, conduct, and analysis and reporting of clinical trials through the development and application of methodological research to clinical trials from CHaRT. 

My undergrad degree is in Mathematics from the University of Aberdeen, graduating in 1997. After a year training as a Mathematics teacher I joined the Unit in September 1998 as a statistician. I studied part-time for an MSc in Applied Statistics with Sheffield Hallam University, graduating in 2004. In 2008 I was appointed Senior Statistican, and in 2016 was I Interim Programme Director for the Health Care Assessment Programme, until being appointment as CHaRT Director in April 2017.  

Qualifications

  • BSc Mathematics 
    1997 - University of Aberdeen 
  • MSc Applied Statistics 
    2004 - Sheffield Hallam University 
Research

Research Overview

The application of statistical methods to clinical trials. Recent example is JCE paper available here on using instrumental variables in a surgery trial to address non-compliance. Collaborators were Jonathan Cook (Oxford), Tom Palmer (Lancaster), and Richard Emesley (Manchester). 

Research on making trials more efficient, collaborating with Trial Forge. 

Current Research

A complete list of the CHaRT RCT portolio is available by clicking here

Teaching

Teaching Responsibilities

I teach on our MPH course module PU5031: EVIDENCE-BASED HEALTH.

Publications

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  • Correction to: Pulpotomy for the Management of Irreversible Pulpitis in Mature Teeth (PIP): a feasibility study (Pilot and Feasibility Studies, (2022), 8, 1, (77), 10.1186/s40814-022-01029-9)

    Clarkson, J. E., Ramsay, C. R., Mannocci, F., Jarad, F., Albadri, S., Ricketts, D., Tait, C., Banerjee, A., Deery, C., Boyers, D., Marshman, Z., Goulao, B., Hamilton, A. R., Banister, K., Bell, R., Brown, L., Conway, D. I., Donaldson, P., Duncan, A., Dunn, K., Fee, P., Forrest, M., Glenny, A. M., Gouick, J., Gupta, E., Jacobsen, E., Kettle, J., MacLennan, G., Macpherson, L., McGuff, T., Mitchell, F., van der Pol, M., Moazzez, R., Roberston, D., Wojewodka, G., Young, L., Lamont, T.
    Pilot and Feasibility Studies, vol. 8, 82
    Contributions to Journals: Comments and Debates

  • Single-incision mini-slings versus standard synthetic mid-urethral slings for surgical treatment of stress urinary incontinence in women: The SIMS RCT

    Abdel-Fattah, M., Cooper, D., Davidson, T., Kilonzo, M., Boyers, D., Bhal, K., McDonald, A., Wardle, J., N'Dow, J., MacLennan, G., Norrie, J.
    Health technology assessment (Winchester, England), vol. 26, no. 47, pp. 1-190
    Contributions to Journals: Articles

  • Photodynamic versus white-light-guided resection of first-diagnosis non-muscle-invasive bladder cancer: PHOTO RCT

    Heer, R., Lewis, R., Duncan, A., Penegar, S., Vadiveloo, T., Clark, E., Yu, G., Mariappan, P., Cresswell, J., McGrath, J., N'Dow, J., Nabi, G., Mostafid, H., Kelly, J., Ramsay, C., Lazarowicz, H., Allan, A., Breckons, M., Campbell, K., Campbell, L., Feber, A., McDonald, A., Norrie, J., Orozco-Leal, G., Rice, S., Tandogdu, Z., Taylor, E., Wilson, L., Vale, L., MacLennan, G., Hall, E.
    Health technology assessment (Winchester, England), vol. 26, no. 40, pp. 1-144
    Contributions to Journals: Articles

  • The Achieving Self-directed Integrated Cancer Aftercare Intervention for Detection of Recurrent and Second Primary Melanoma in Survivors of Melanoma: Pilot Randomized Controlled Trial

    Murchie, P., Constable, L., Hall, S., Brant, W., Allan, J., Johnston, M., Masthoff, J., Lee, A., Treweek, S., Ayansina, D., Proby, C., Rahman, K., Walter, F., Burrows, N., Durrani, A., Maclennan, G.
    JMIR cancer, vol. 8, no. 3, e37539
    Contributions to Journals: Articles

  • PROSPECT: 4- and 6-year follow-up of a randomised trial of surgery for vaginal prolapse

    Reid, F. M., Aucott, L., Glazener, C. M., Elders, A., Hemming, C., Cooper, K. G., Freeman, R. M., Smith, A. R., Hagen, S., Kilonzo, M., Boyers, D., MacLennan, G., Norrie, J., Breeman, S., [for the PROSPECT study group]
    International Urogynecology Journal
    Contributions to Journals: Articles

  • Cost utility analysis of shockwave lithotripsy versus ureteroscopic stone treatment in adults

    Kilonzo, M. M., Dasgupta, R., Thomas, R., Aucott, L., MacLennan, S., Lam, T., Anson, K., Cameron, S., Starr, K., Burgess, N., Keeley, F. X., Clark, C. T., N’Dow, J., MacLennan, G., McClinton, S.
    BJU International
    Contributions to Journals: Articles

  • Randomised controlled trial comparing the clinical and cost-effectiveness of various washout policies versus no washout policy in preventing catheter associated complications in adults living with long-term catheters: study protocol for the CATHETER II study

    Abdel-fattah, M., Johnson, D., Constable, L., Thomas, R., Cotton, S., Tripathee, S., Cooper, D., Boran, S., Dimitropoulos, K., Evans, S., Granitsiotis, P., Hashim, H., Kilonzo, M., Larcombe, J., Little, P., MacLennan, S., Murchie, P., Myint, P., N’Dow, J., Norrie, J., Omar, M. I., Paterson, C., Scotland, G., Thiruchelvam, N., MacLennan, G.
    Trials, vol. 23, no. 1, 630
    Contributions to Journals: Articles

  • Male synthetic sling or artificial urinary sphincter (AUS) for men with urodynamic stress incontinenceafter prostate surgery: the MASTER non-inferiority randomised controlled trial

    Constable, L., Abrams, P., Cooper, D., Kilonzo, M., Cotterill, N., Harding, C. K., Drake, M. J., Pardoe, M. N., McDonald, A., Smith, R., Norrie, J., McCormack, K., Ramsay, C., Uren, A., Mundy, T., Glazener, C., MacLennan, G.
    Health Technology Assessment, vol. 26, no. 36
    Contributions to Journals: Articles

  • Remotely delivered cognitive behavioural and personalised exercise interventions for fatigue severity and impact in inflammatory rheumatic diseases: a multi-centre randomised controlled parallel open-label group trial (LIFT)

    Bachmair, E., Martin, K., Aucott, L., Dhaun, N., Dures, E., Emsley, R., Gray, S. R., Kidd, E., Kumar, V., Lovell, K., MacLennan, G., McNamee, P., Norrie, J., Paul, L., Packham, J., Ralston, S. H., Siebert, S., Wearden, A., LIFT study group, Macfarlane, G., Basu, N.
    The Lancet Rheumatology, vol. 4, no. 8, pp. e534-e545
    Contributions to Journals: Articles

  • Cost-effectiveness of primary surgical versus primary medical management in the treatment of patients presenting with advanced glaucoma

    Kernohan, A., Homer, T., Shabaninejad, H., King, A. J., Hudson, J., Fernie, G., Azuara-Blanco, A., Burr, J., Sparrow, J. M., Garway-Heath, D., Barton, K., Norrie, J., Maclennan, G., Vale, L.
    British Journal of Ophthalmology
    Contributions to Journals: Articles
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