Professor Claude Wischik
Chair in Mental Health (Clin)
- About
-
- Email Address
- c.m.wischik@abdn.ac.uk
- Office Address
TauRx Therapeutics Ltd
1st Floor, Sir Moir Lockhead Building
395 King Street
Aberdeen
AB24 5RP
United Kingdom
- School/Department
- School of Medicine, Medical Sciences and Nutrition
- Research
-
Research Overview
Molecular Neuropathology of Alzheimer's Disease, and in particular the therapeutic intervention of tau pathology
- Publications
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Page 1 of 12 Results 1 to 10 of 111
Inhibiting disulphide bonding in truncated tau297-391 results in enhanced self-assembly of tau into seed-competent assemblies
ACS Chemical Neuroscience, vol. 17, no. 1, pp. 124-138Contributions to Journals: ArticlesEffects of hydromethylthionine mesylate and rivastigmine in a pharmacological mouse model of Alzheimer's disease
Behavioural Pharmacology, pp. 64-69Contributions to Journals: Articles- [ONLINE] DOI: https://doi.org/10.1097/FBP.0000000000000865
Quantification of plasma tau species containing the proline-rich region as a biomarker in Alzheimer’s disease
Scientific Reports, vol. 15, 41881Contributions to Journals: Articles- [ONLINE] DOI: https://doi.org/10.1038/s41598-025-25864-x
- [OPEN ACCESS] http://aura.abdn.ac.uk/bitstreams/82867189-e587-4cae-9b66-e8593ec53c83/download
- [ONLINE] View publication in Scopus
A key region of Tau that is able to drive assembly and modulate inhibition by Hydromethylthionine
Journal of Molecular Biology, vol. 437, no. 17, 169231Contributions to Journals: Articles- [ONLINE] DOI: https://doi.org/10.1016/j.jmb.2025.169231
- [OPEN ACCESS] http://aura.abdn.ac.uk/bitstreams/7a09658e-98e2-46e0-b61c-ea4a48f823ab/download
- [ONLINE] View publication in Scopus
Proteomic and non-proteomic changes of presynaptic proteins in animal models of Alzheimer’s disease: A meta-analysis 2015-2023
Journal of Alzheimer's Disease, vol. 107, no. 2, pp. 452-476Contributions to Journals: ArticlesRole of 18F-florzolotau PET in diagnostic and therapeutic decision-making for cognitive impairment
Alzheimer's & dementia : the journal of the Alzheimer's Association, vol. 21, no. 8, e70563Contributions to Journals: Articles- [ONLINE] DOI: https://doi.org/10.1002/alz.70563
- [OPEN ACCESS] http://aura.abdn.ac.uk/bitstreams/019992bc-c02d-48ce-afa4-a00b14c06599/download
FDG-PET Image Classification in Alzheimer’s Disease: from Traditional Visual Analysis to Advanced Transfer Learning
Nuclear Medicine and Molecular Imaging, vol. 59, pp. 201-208Contributions to Journals: Articles- [ONLINE] https://pubmed.ncbi.nlm.nih.gov/40385367/
- [ONLINE] DOI: https://doi.org/10.1007/s13139-025-00908-2
Hydromethylthionine sustains truncated tau-dependent inflammation-lowering effects in mouse brain
FEBS Journal, vol. 292, no. 10, pp. 2602-2623Contributions to Journals: Articles- [ONLINE] DOI: https://doi.org/10.1111/febs.70021
- [OPEN ACCESS] http://aura.abdn.ac.uk/bitstreams/372a1f89-dc2a-4be5-a64e-19083dc6d8d6/download
- [ONLINE] View publication in Scopus
Inhibiting disulphide bonding in truncated tau297-391 results in enhanced self-assembly of tau into seed-competent assemblies
Working Papers: Preprint Papers- [ONLINE] DOI: https://doi.org/10.1101/2025.02.05.636249
Obtaining personalized predictions from a randomized controlled trial on Alzheimer’s disease
Scientific Reports, vol. 15, 1671Contributions to Journals: Articles