Dr Thomas Baddeley
Senior Research Fellow
- About
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- Telephone Number
- +44 (0)1224 274238
- School/Department
- School of Natural and Computing Sciences
- Research
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Research Overview
The development and use of new analytical methods in the study of small organic molecules undergoing clinical evaluation.
The synthesis and study of novel organic compounds for use as potential drug candiates and excipients.
The study of the physical properties of novel oligosaccharides
- Publications
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Page 2 of 4 Results 11 to 20 of 33
In Vitro Maturation of a Humanized Shark VNAR Domain to Improve Its Biophysical Properties to Facilitate Clinical Development
Frontiers in Immunology, vol. 8, 1361Contributions to Journals: Articles- [ONLINE] DOI: https://doi.org/10.3389/fimmu.2017.01361
- [OPEN ACCESS] http://aura.abdn.ac.uk/bitstream/2164/9601/1/fimmu_08_01361.pdf
Crystal structures of four 1-(aryl)-[1,2,4]triazolo[4,3-a]quinoxaline derivatives
Journal of Molecular Structure, vol. 1128, pp. 579-589Contributions to Journals: Articles- [ONLINE] DOI: https://doi.org/10.1016/j.molstruc.2016.09.021
Complex Disposition of Methylthioninium Redox Forms Determines Efficacy in Tau Aggregation Inhibitor Therapy for Alzheimer's Disease
Journal of Pharmacology and Experimental Therapeutics, vol. 352, no. 1, pp. 110-118Contributions to Journals: Articles- [ONLINE] DOI: https://doi.org/10.1124/jpet.114.219352
Tautomers and polymorphs of pyrazolinone derivatives, generated from reactions of arylhydrazines, ArNHNH2, with 1,3-dicarbonyl compounds
Zeitschrift fur Kristallographie, vol. 228, no. 2, pp. 77-91Contributions to Journals: Articles- [ONLINE] DOI: https://doi.org/10.1524/zkri.2013.1575
- [ONLINE] View publication in Scopus
New phenothiazine diaminium compounds are tau protein aggregation inhibitors, useful to treat e.g. Alzheimer's disease, Pick's disease, progressive supranuclear palsy, frontotemporal dementia and frontotemporal lobar degeneration syndromes
Patents: PatentsVariation in supramolecular arrangements of hydrazones, o-H2NC6H4CMe=NNHC6H4X (X = H, o-, m- and p-NO2), derived from o-aminoacetophenone and phenylhydrazines
Journal of Molecular Structure, vol. 1020, pp. 16-22Contributions to Journals: Articles- [ONLINE] DOI: https://doi.org/10.1016/j.molstruc.2012.04.023
1,3-Diphenyl-4,5-dihydro-1H-pyrazol-5-one
Acta Crystallographica Section E: Structure Reports Online, vol. E68, pp. o1016-o1017Contributions to Journals: Articles- [ONLINE] DOI: https://doi.org/10.1107/S1600536812009567
3,7-diamino-10H-phenothiazine salts and their use: WO2007110627
Patents: Patents(Pyrazinecarbonyl)hydrazone halobenzaldehydes: Supramolecular arrays generated by face to face stacking of ribbons, formed from C-H-O interactions
Zeitschrift fur Kristallographie, vol. 224, no. 10, pp. 506-514Contributions to Journals: Articles- [ONLINE] DOI: https://doi.org/10.1524/zkri.2009.1182
- [ONLINE] View publication in Scopus
2-Hydroxyacetophenone arylhydrazones. Supramolecular arrangements based on C–H · · · O(H), CH · · · O(NO), N–H · · · O(H), N–H · · · O(NO), C–H · · · π or π · · · π interactions
Zeitschrift für Kristallographie, vol. 224, no. 4, pp. 213-224Contributions to Journals: Articles- [ONLINE] DOI: https://doi.org/10.1524/zkri.2009.1121