Clinical, imaging and blood biomarker outcomes in a Phase 3 clinical trial of tau aggregation inhibitor hydromethylthionine mesylate in mild cognitive impairment and mild to moderate dementia due to Alzheimer’s disease
Wischik, C. M., Stefanacci, R., Bentham, P., Gauthier, S., Zetterberg, H., Wilcock, G. K., Froelich, L., Burns, A., MacSweeney, E., Ballard, C., Yu, J., Choon, T. S., Asvatourian, V., Muehlemann, N., Priel, J., Kook, K., Sullivan, T., Downie, D., Miller, S., Pringle, C., Storey, J. M. D., Baddeley, T., Harrington, C. R., Penny, L. K., Arastoo, M., Staff, R., Sandu, A., Shiells, H., Lo, S., Nazlee, N., Evans, E., Hull, C., Schelter, B. O.
The Journal of Prevention of Alzheimer's Disease, vol. 13, no. 3, 100480
The structural basis for the selective antagonism of soluble TNF-alpha by variable new antigen receptors
Ubah, O., Lake, E. W., Ott, K., Priyanka, S., Celeda, S., Gunaratne, G. S., West, J., Shi, K., Moeller, N. H., Porter, A., Aihara, H., Kosoff, D., LeBeau, A. M., Barelle, C.
Inhibiting disulphide bonding in truncated tau297-391 results in enhanced self-assembly of tau into seed-competent assemblies
Oakley, S. S., Marshall, K. E., Meisl, G., Copsey, A., Maina, M. B., Milton, R., Vorley, T., Storey, J., Harrington, C., Wischik, C., Xue, W., Serpell, L. C.
ACS Chemical Neuroscience, vol. 17, no. 1, pp. 124-138
Comparison of steroidogenic disruption in adrenal H295R and ovarian KGN and COV434 cell models and the implications to assess female reproductive toxicity
Vazakidou, P., Koopmans, C., Nijmeijer, S., Lecante, L. L., Liu, P., Mazaud Guittot, S., Fowler, P. A. F., Leonards, P. E., van Duursen, M. B.
A scoping review of randomised controlled trials of vaccines that recruited care home residents: lessons for future trials
Subbarayan, S., Smith-Dodd, I., Nicolson, G., Burton, J. K., Vasan, S. S., Shenkin, S. D., Soiza, R., The WATCH Consortium, Treweek, S., Stewart, C., Macleod, M.