Publications | The Institute of Medical Sciences

Timing matters: early administration of a high-affinity antibody targeting the tau repeat domain prevents aggregation in a mouse tauopathy model

2026 - Accepted/In press

Porter, A.

Alzheimer's Research & Therapy

Contributions to Journals: Articles

Effects of hydromethylthionine mesylate and rivastigmine in a pharmacological mouse model of Alzheimer's disease

2026

Robinson, L., Bray, J., Melis, V., Harrington, C. R., Wischik, C. M., Riedel, G.

Behavioural Pharmacology, pp. 64-69

Contributions to Journals: Articles

Digital Object Identifier: https://doi.org/10.1097/FBP.0000000000000865

Clinical, imaging and blood biomarker outcomes in a Phase 3 clinical trial of tau aggregation inhibitor hydromethylthionine mesylate in mild cognitive impairment and mild to moderate dementia due to Alzheimer’s disease

2026

Wischik, C. M., Stefanacci, R., Bentham, P., Gauthier, S., Zetterberg, H., Wilcock, G. K., Froelich, L., Burns, A., MacSweeney, E., Ballard, C., Yu, J., Choon, T. S., Asvatourian, V., Muehlemann, N., Priel, J., Kook, K., Sullivan, T., Downie, D., Miller, S., Pringle, C., Storey, J. M. D., Baddeley, T., Harrington, C. R., Penny, L. K., Arastoo, M., Staff, R., Sandu, A., Shiells, H., Lo, S., Nazlee, N., Evans, E., Hull, C., Schelter, B. O.

The Journal of Prevention of Alzheimer's Disease, vol. 13, no. 3, 100480

Contributions to Journals: Articles

Online: https://www.sciencedirect.com/science/article/pii/S227458072600004X
Digital Object Identifier: https://doi.org/10.1016/j.tjpad.2026.100480
Open Access: http://aura.abdn.ac.uk/bitstreams/75aac545-e8a2-4266-92e5-bf2b51de39fc/download

The structural basis for the selective antagonism of soluble TNF-alpha by variable new antigen receptors

2026

Ubah, O., Lake, E. W., Ott, K., Priyanka, S., Celeda, S., Gunaratne, G. S., West, J., Shi, K., Moeller, N. H., Porter, A., Aihara, H., Kosoff, D., LeBeau, A. M., Barelle, C.

Nature Communications, vol. 17, 256

Contributions to Journals: Articles

Digital Object Identifier: https://doi.org/10.1038/s41467-025-66967-3
Open Access: http://aura.abdn.ac.uk/bitstreams/57c7ae6d-fc4e-4c8f-aeb1-0b6cf5d97be5/download

Inhibiting disulphide bonding in truncated tau297-391 results in enhanced self-assembly of tau into seed-competent assemblies

2026

Oakley, S. S., Marshall, K. E., Meisl, G., Copsey, A., Maina, M. B., Milton, R., Vorley, T., Storey, J., Harrington, C., Wischik, C., Xue, W., Serpell, L. C.

ACS Chemical Neuroscience, vol. 17, no. 1, pp. 124-138

Contributions to Journals: Articles

Digital Object Identifier: https://doi.org/10.1021/acschemneuro.5c00639
Open Access: http://aura.abdn.ac.uk/bitstreams/9a4ac37d-645d-4169-8d5b-f4f01f76ce49/download

Systematic gait analysis in alpha-synuclein transgenic line 62 mice using the CatWalk

2026

Schwab, K., Robinson, L., Bray, J., Anschuetz, A., Mondesir, M., Magri', M., Harrington, C., Riedel, G.

Behavioural Brain Research, vol. 496, 115819

Contributions to Journals: Articles

Digital Object Identifier: https://doi.org/10.1016/j.bbr.2025.115819
Open Access: http://aura.abdn.ac.uk/bitstreams/7c7b8eee-d670-4e6e-9d18-97a78483d184/download

Association of neighbourhood deprivation with secondary prevention prescribing and all-cause mortality among stroke patients in Scotland: a population-based study

2026

Sterling, K., Turner, M., Langhorne, P., Macleod, M.

Cerebrovascular Diseases, vol. 55, no. 1, pp. 63-71

Contributions to Journals: Articles

Digital Object Identifier: https://doi.org/10.1159/000546261
Open Access: http://aura.abdn.ac.uk/bitstreams/a565bdbc-1c17-4a36-af08-51f3df3524ae/download
Additional Links: View publication in Scopus

Comparison of steroidogenic disruption in adrenal H295R and ovarian KGN and COV434 cell models and the implications to assess female reproductive toxicity

2026

Vazakidou, P., Koopmans, C., Nijmeijer, S., Lecante, L. L., Liu, P., Mazaud Guittot, S., Fowler, P. A. F., Leonards, P. E., van Duursen, M. B.

Reproductive Toxicology, vol. 139, pp. 109088

Contributions to Journals: Articles

Digital Object Identifier: https://doi.org/10.1016/j.reprotox.2025.109088
Open Access: http://aura.abdn.ac.uk/bitstreams/3d396091-3127-40d9-a956-6615758203e9/download

Investigation into ligand selectivity and bias at the formyl peptide receptor family

2026

Jack, C. E., Thomson, C. M., Dall’Angelo, S., Thompson, D., Hislop, J. N.

Journal of Pharmacology and Experimental Therapeutics, vol. 393, no. 1, 103764

Contributions to Journals: Articles

Digital Object Identifier: https://doi.org/10.1016/j.jpet.2025.103764
Open Access: http://aura.abdn.ac.uk/bitstreams/99b140b9-fc97-45f5-928b-83c065c6adc5/download

A2A Adenosine Receptor Agonists With Last-Step Enzymatic 18F-Labelling Potential (Fluorinase) for Positron Emission Tomography (PET)

2025 - E-pub ahead of print

Charalambous, N., Schleidt, C., Liu, R., Heitman, L. H., Dall’Angelo, S., O’Hagan, D., Lowe, P. T.

European Journal of Organic Chemistry, e202501125

Contributions to Journals: Articles

Digital Object Identifier: https://doi.org/10.1002/ejoc.202501125

Effect of the Icelandic Mutation APP^A673T in the Murine APP Gene on Phenotype of Line 66 Tau Mice

2025

Anschuetz, A., Robinson, L., Mondesir, M., Melis, V., Platt, B., Harrington, C. R., Riedel, G., Schwab, K.

Biomolecules, vol. 16, no. 1, 28

Contributions to Journals: Articles

Digital Object Identifier: https://doi.org/10.3390/biom16010028
Additional Links: View publication in Scopus

Characterising interleukin-27 (IL-27) responses in human blood derived macrophage cells

2026

Helps, T., Baker, C., Wilson, H. M., Arthur, S., Murray, G. I., McLean, M. H.

Cytokine, vol. 198, 157097

Contributions to Journals: Articles

Online: https://www.sciencedirect.com/science/article/pii/S1043466625002443
Digital Object Identifier: https://doi.org/10.1016/j.cyto.2025.157097
Open Access: http://aura.abdn.ac.uk/bitstreams/3e7fe931-d2d8-4471-9b22-612503b2102a/download

Fast zero-shot deep learning-based denoising method for low-field MR images

2025 - E-pub ahead of print

Ayde, R., Zihlmann, G., Salameh, N., Sarracanie, M.

Magnetic Resonance Materials in Physics, Biology and Medicine

Contributions to Journals: Articles

Digital Object Identifier: https://doi.org/10.1007/s10334-025-01311-w
Open Access: http://aura.abdn.ac.uk/bitstreams/4c9541fb-5108-42f8-a502-523af1f96d7d/download
Additional Links: View publication in Scopus

Hyphal growth determines spatial organization and coexistence in a pathogenic polymicrobial community in a spatially structured environment

2025

Mancini, L., Saliekh, L., Claydon, R., Kotar, J., Benyei, E. B., Munro, C. A., Shendruk, T. N., Brown, A., Welch, M., Cicuta, P.

The ISME Journal, vol. 19, no. 1, pp. wraf279

Contributions to Journals: Articles

Digital Object Identifier: https://doi.org/10.1093/ismejo/wraf279
Open Access: http://aura.abdn.ac.uk/bitstreams/5a520a70-90d9-4170-a8ba-5fc5c6ab3d5a/download

A scoping review of randomised controlled trials of vaccines that recruited care home residents: lessons for future trials

2025

Subbarayan, S., Smith-Dodd, I., Nicolson, G., Burton, J. K., Vasan, S. S., Shenkin, S. D., Soiza, R., The WATCH Consortium, Treweek, S., Stewart, C., Macleod, M.

Age and Ageing, vol. 54, no. 12, afaf355

Contributions to Journals: Articles

Digital Object Identifier: https://doi.org/10.1093/ageing/afaf355
Open Access: http://aura.abdn.ac.uk/bitstreams/042377b1-a7c0-4f28-b2be-141e5228d177/download

Profound cell wall remodeling in Candida parapsilosis during systemic infection confers simultaneous tolerance to echinocandins and host immunity

2025 - Accepted/In press

Daneshnia, F., Cai, L., Gunasekaran, D., Gautam, I., Perry, A., Ghahfarokhy, P. M., Ebadati, A., Munoz, J., Padilla, D., Hilmioglu-Polat, S., Mei, S., Floyd, D. J., Schikora-Tamarit, M. �., Funtes, D., Artigués-Lleixà, M., Walker, L., Gonçalves, S. M., Salehi, M., Carvalho, A., Desai, J. V., Perlin, D. S., Munro, C., Hopke, A., Wang, T., Gabaldón, T., Fang, W., Nobile, C. J., Mansour, M. K., Arastehfar, A.

Microbiology spectrum

Contributions to Journals: Articles

Physical Exercise or Cognitive Behavioral Therapy for Takotsubo Cardiomyopathy: A Randomized Controlled Trial

2025 - E-pub ahead of print

Gamble, D. T., Ross, J., Khan, M., Cheyne, L., Rudd, A., Srinivasan, J., Horgan, G., Hogg, D., Myint, P. K., Newby, D. E., Williams, C., Gray, S., Dawson, D.

Circulation. Heart Failure

Contributions to Journals: Articles

Digital Object Identifier: https://doi.org/10.1161/CIRCHEARTFAILURE.125.013229

A comparison of T1ρ with native T1 and T2 mapping for detecting oedema in Takotsubo cardiomyopathy

2025

Balode, L., Kelly, R., Higgins, D. M., Gamble, D., Dawson, D., Ross, P. J.

Journal of Cardiovascular Magnetic Resonance, vol. 27, no. 2, 101965

Contributions to Journals: Articles

Digital Object Identifier: https://doi.org/10.1016/j.jocmr.2025.101965
Open Access: http://aura.abdn.ac.uk/bitstreams/8662aa31-2b20-41af-b517-a4bd49e782d3/download

Exploring the roles of conserved context-dependent cis-regulatory elements (ccdCREs) in multicellularity, human health and disease

2025

McEwan, A. R., Rattray, A., Hutchings, G., Hay, E. A., Murgatroyd, C., MacKenzie, A.

FEBS Journal, vol. 292, no. 23, pp. 6163-6181

Contributions to Journals: Articles

Digital Object Identifier: https://doi.org/10.1111/febs.70174
Open Access: http://aura.abdn.ac.uk/bitstreams/2c996e73-a60d-4020-a024-0fe503ad3ce7/download

Generation of a Ym1 Deficient Mouse utilising CRISPR-Cas9 in CB6 Embryos

2025

Parkinson, J. E., Baldwin, G. E., Papotto, P. H., Humphreys, N. E., Day, A. J., Adamson, A. D., Allen, J. E., Sutherland, T.

Transgenic Research, vol. 34, 44

Contributions to Journals: Articles

Digital Object Identifier: https://doi.org/10.1007/s11248-025-00455-8
Open Access: http://aura.abdn.ac.uk/bitstreams/37246ce9-2c1d-4057-baf6-147a283e5f0f/download

How many people have a Huntington's Disease expansion: A population-based prevalence study in Northern Scotland

2025

Cruickshank, H., Miedzybrodzka, Z.

Neuroepidemiology, vol. 59, no. 6, pp. 633–640

Contributions to Journals: Articles

Digital Object Identifier: https://doi.org/10.1159/000542739
Open Access: http://aura.abdn.ac.uk/bitstreams/721bd4a1-3c4f-4c63-8ab7-5efedaa20752/download
Additional Links: View publication in Scopus

In vitro evolution of caspofungin resistance in Candidozyma auris via FKS1 hotspot I mutations results in moderate fitness trade-offs but no reduction in virulence

2025

Ross, Z. K., Alsayegh, S., Zhao, Y., McPherson, S., Munro, C. A., Lorenz, A.

Microbiological Research, vol. 301, 128322

Contributions to Journals: Articles

Digital Object Identifier: https://doi.org/10.1016/j.micres.2025.128322
Open Access: http://aura.abdn.ac.uk/bitstreams/f8d4ecd9-392c-46b5-8bb1-72a2940e5a3b/download

Sex-specific all-cause mortality is associated with adiposity in the Malaysian Elders Longitudinal Research (MELoR) study

2025

Hashim, N. N. A., Mat, S., Myint, P. K., Delibegovic, M., Kioh, S. H., Bahyah Kamaruzzaman, S., Hairi, N. N., Khoo, S., Chin, A., Tan, M. P.

Annals of Geriatric Medicine and Research, vol. 29, no. 4, pp. 496-506

Contributions to Journals: Articles

Digital Object Identifier: https://doi.org/10.4235/agmr.24.0167
Open Access: http://aura.abdn.ac.uk/bitstreams/43c090f6-d7d1-4fd3-bfad-889af78bbc74/download
Additional Links: Pubmed Link; View publication in Scopus

Quantification of plasma tau species containing the proline-rich region as a biomarker in Alzheimer’s disease

2025

Arastoo, M., Penny, L., Lofthouse, R. A., Hitchcock, A., Moelders, A. R., Szalma, S., Porter, A., Palliyil, S., Harrington, C., Wischik, C.

Scientific Reports, vol. 15, 41881

Contributions to Journals: Articles

Digital Object Identifier: https://doi.org/10.1038/s41598-025-25864-x
Open Access: http://aura.abdn.ac.uk/bitstreams/82867189-e587-4cae-9b66-e8593ec53c83/download
Additional Links: View publication in Scopus

Bioactivity Profiles of Progressively Ring-Fluorinated Cyclohexyl Motifs in the WKYMVm Peptide as Formylpeptide FPR2 Agonists and in Keto-Piperazines as Antitrypanosome Agents

2025

He, M., Thomson, C., Thompson, D., Kuodis, V., Smith, T., Dall'Angelo, S., O'hagan, D.

ChemBioChem, vol. 26, no. 22, e202500384

Contributions to Journals: Articles

Digital Object Identifier: https://doi.org/10.1002/cbic.202500384
Open Access: http://aura.abdn.ac.uk/bitstreams/8ec773fe-c496-471e-8896-ac88afe6b52e/download
Additional Links: View publication in Scopus

Clinical care of family members of patients with dilated cardiomyopathy: a Clinical Consensus Statement of the Heart Failure Association of the ESC, the ESC Working Group on Myocardial & Pericardial Diseases, and the ESC Council on Cardiovascular Genomics

2025

Verdonschot, J., Kaski, J. P., Asselbergs, F. W., Behr, E., Charron, P., Dawson, D., Haugaa, K., Kuchynka, P., Lopes, L., Mazzanti, A., Monserrat, L., Pantazis, A., Prasad, S. K., Schunkert, H., Seferovic, P., Sheppard, M. N., Sinagra, G., van Tintelen, P., Tome Esteban, M. T., Heymans, S., Pavia, P. G.

European Heart Journal, vol. 46, no. 43, pp. 4569–4582

Contributions to Journals: Articles

Digital Object Identifier: https://doi.org/10.1093/eurheartj/ehaf571
Open Access: http://aura.abdn.ac.uk/bitstreams/97db50b1-0f34-4d36-b197-baad9b1eba12/download

Discrimination of haematoma and peri-haematoma regions of sub-acute intracerebral haemorrhage using Field-Cycling Imaging at field strengths below 0.2 T

2025

Senn, N., Mallikourti, V., Ross, J., Levi, R., Oren, N., Broche, L., Waiter, G., Macleod, M.

Chapters in Books, Reports and Conference Proceedings: Conference Proceedings

Digital Object Identifier: https://doi.org/10.1177/17474930251379781

Stroke Diagnosis from Field-Cycling Imaging using Machine Learning

2025

Ali-Gombe, A., Senn, N., Broche, L., Mallikourti, V., Ross, J., Waiter, G., Macleod, M.

Chapters in Books, Reports and Conference Proceedings: Conference Proceedings

Digital Object Identifier: https://doi.org/10.1177/17474930251379781

Epigenetic and Structural Brain Aging and Their Associations With Major Depressive Disorder

2025

Xu, E. Y., Green, C., McCartney, D. L., Han, L. K., Evans, K. L., Walker, R. M., Gadd, D. A., Steele, D., Waiter, G., Campbell, A., Lawrie, S. M., Cole, J. H., McIntosh, A. M., Shen, X., Whalley, H. C.

Biological Psychiatry Global Open Science, vol. 5, no. 6, pp. 100577

Contributions to Journals: Articles

Digital Object Identifier: https://doi.org/10.1016/j.bpsgos.2025.100577
Open Access: http://aura.abdn.ac.uk/bitstreams/5cf54a64-3fd3-4f73-8068-6206821ca431/download
Additional Links: View publication in Scopus

Identification of a regulatory sequence within the third intracellular loop that governs β-arrestin binding to the muscarinic M5 receptor

2025

Steinmüller, S., Thompson, K., Alenfelder, J., Drube, J., Hoffmann, C., Kostenis, E., Thompson, D., Hislop, J.

Cellular Signalling, vol. 135, 112004

Contributions to Journals: Articles

Digital Object Identifier: https://doi.org/10.1016/j.cellsig.2025.112004
Open Access: http://aura.abdn.ac.uk/bitstreams/5ff1ddbd-0e5e-474f-8030-000c61ab9e08/download

Retrospective use of the Pragmatic-Explanatory Continuum Indicator Summary-2 trial design tool to assess design choices in randomized controlled trials: an empirical review

2025

Willis, A., Shiely, F., Howie, A., Treweek, S., Taljaard, M., Loudon, K., Murphy, E., Bhakoo, A., Yazdani, Y., Ward, F., Janiaud, P., Haren, A., Yining Liang, A., Robinson, C., Deng, D., Hemkens, L., O'Sullivan Greene, E., Slattery, L., Zwarenstein, M.

Journal of Clinical Epidemiology, vol. 187, 111959

Contributions to Journals: Articles

Digital Object Identifier: https://doi.org/10.1016/j.jclinepi.2025.111959
Open Access: http://aura.abdn.ac.uk/bitstreams/fbb883b9-9c9c-4075-a8f1-6995fa3f38e4/download

Transdiagnostic Alterations in White Matter Microstructure Associated with Suicidal Thoughts and Behaviours in the ENIGMA Suicidal Thoughts and Behaviours Consortium

2025

Van Velzen, L. S., Colic, L., Ceja, Z., Dauvermann, M. R., Villa, L. M., Savage, H. S., Toenders, Y. J., Dehestani, N., Zhu, A. H., Campos, A. I., Salminen, L. E., Alda, M., Agartz, I., Alexander, N., Ayesa-Arriola, R., Ballard, E. D., Banaj, N., Barkhau, C., Başgöze, Z., Bauer, J., Benedetti, F., Berger, K., Besteher, B., Brosch, K., Canal-Rivero, M., Cervenka, S., Colle, R., Connolly, C. G., Corruble, E., Courtet, P., Couvy-Duchesne, B., Crespo-Facorro, B., Cullen, K. R., Dannlowski, U., Deverdun, J., Diaz-Zuluaga, A. M., Dietze, L. M. F., Evans, J. W., Fani, N., Flinkenflügel, K., Friedman, N. P., Gotlib, I. H., Groenewold, N. A., Grotegerd, D., Hajek, T., Hatoum, A. S., Hermesdorf, M., Hickie, I. B., Hirano, Y., Ho, T. C., Ikemizu, Y., Iorfino, F., Ipser, J., Isobe, Y., Jackowski, A. P., Jollant, F., Kircher, T., Klug, M., Koopowitz, S., Kraus, A., Krug, A., le Bars, E., Leehr, E. J., Li, M., Lippard, E. T. C., Lopez-Jaramillo, C., Maximov, I. I., McIntosh, A. M., McLaughlin, K. A., McWhinney, S. R., Meinert, S., Melloni, E., Mitchell, P. B., Mwangi, B., Nenadić, I., Nerland, S., Olié, E., Ortiz-García de la Foz, V., Pan, P. M., Pereira, F., Piras, F., Piras, F., Poletti, S., Reineberg, A. E., Roberts, G., Romero-García, R., Sacchet, M. D., Salum, G. A., Sandu-Giuraniuc, A., Sellgren, C. M., Shimizu, E., Smolker, H., Soares, J. C., Douglas Steele, J., Stein, F., Stein, D. J., Straube, B., Teutenberg, L., Thomas-Odenthal, F., Usemann, P., Valabregue, R., Valencia-Echeverry, J., Wagner, G., Waiter, G., Walter, M., Whalley, H. C., Wu, M., Yang, T. T., Zarate, C. A., Zugman, A., Zunta-Soares, G., van Heeringen, K., van Rooij, S. J. H., van der Wee, N., van der Werff, S., Thompson, P. M., Blumberg, H. P., van Harmelen, A., Rentería, M. E., Jahanshad, N., ENIGMA Consortium, Schmaal, L.

Translational Psychiatry, vol. 15, 429

Contributions to Journals: Articles

Digital Object Identifier: https://doi.org/10.1038/s41398-025-03602-1
Open Access: http://aura.abdn.ac.uk/bitstreams/bb0db951-f19d-40b9-8404-d3785f630f7e/download

The protein-protein interaction between two spliced leader trans-splicing factors is mediated by two interlinked α-helical domains

2025

Eijlers, P., Pettitt, J., Müller, B.

microPublication Biology, 001705

Contributions to Journals: Articles

Online: https://www.micropublication.org/journals/biology/micropub-biology-001705
Digital Object Identifier: https://doi.org/10.17912/MICROPUB.BIOLOGY.001705

Takotsubo syndrome: cognitive behavioural therapy, physical training, and brain function recovery in the BREAKOUT trial

2025

Khan, H., Gamble, D., Rudd, A., Dospinescu, C., Creaney, C., Horgan, G., Holme, A. L., Wilson, H., Newby, D. E., Gray, S., Krishnadas, R., Williams, C., Waiter, G., Dawson, D.

European Heart Journal, vol. 46, no. 40, pp. 4127-4129

Contributions to Journals: Articles

Digital Object Identifier: https://doi.org/10.1093/eurheartj/ehaf441
Open Access: http://aura.abdn.ac.uk/bitstreams/0886a4e1-0de4-43e3-9fbe-bbdedce5ab4e/download

Blood Biomarkers from Research Use to Clinical Practice: What Must Be Done? A Report from the EU/US CTAD Task Force

2025

Angioni, D., Delrieu, J., Hansson, O., Fillit, H., Aisen, P., Cummings, J., Sims, J. R., Braunstein, J. B., Sabbagh, M., Bittner, T., Pontecorvo, M., Bozeat, S., Dage, J. L., Largent, E., Mattke, S., Correa, O., Gutierrez Robledo, L. M., Baldivieso, V., Willis, D. R., Atri, A., Bateman, R. J., Ousset, P. J., Vellas, B., Weiner, M., EU/US/CTAD Task Force, Penny, L., Harrington, C.

Journal of Prevention of Alzheimer's Disease, vol. 9, no. 4, pp. 569-579

Contributions to Journals: Articles

Digital Object Identifier: https://doi.org/10.14283/jpad.2022.85
Open Access: http://aura.abdn.ac.uk/bitstreams/2bf41f9a-60f5-4b5b-b98f-671d243fb570/download
Additional Links: View publication in Scopus; https://abdn.elsevierpure.com/en/publications/46864cff-6f39-49e4-97f5-7b93c5ec7414

PTP1B deficiency in myeloid cells increases susceptibility to Candida albicans systemic infection by modulating antifungal immunity

2025

Allen, B., Dambuza, I. M., Berry, S., Reid, D. M., McVey, S. M., Mesiarikova, M., John, L., Davie, M., Baker, C. P., Arthur, J. S. C., Delibegovic, M., Brown, G. D., Wilson, H.

mBio, vol. 16, no. 10, e01516-25

Contributions to Journals: Articles

Digital Object Identifier: https://doi.org/10.1128/mbio.01516-25
Open Access: http://aura.abdn.ac.uk/bitstreams/5e6687cb-f0ab-4820-8650-11a6d0348159/download
Additional Links: https://abdn.elsevierpure.com/en/publications/41d1cdee-8f38-47d4-a0c3-9d7c736c3e40

The Influence of Birth Weight, Socio-Economic Status, and Adult Health on Brain Volumes during Ageing

2025

McNeil, C., Habota, T., Sandu-Giuraniuc, A., Waiter, G., Whalley, H. C., Murray, A. D., Murray, A. D.

Neuroepidemiology, vol. 59, no. 5, pp. 489-497

Contributions to Journals: Articles

Digital Object Identifier: https://doi.org/10.1159/000541918
Open Access: http://aura.abdn.ac.uk/bitstreams/1cfd09f7-6051-4157-a038-d35e9bf88b3c/download
Additional Links: https://abdn.elsevierpure.com/en/publications/aed6ec47-5772-4c0c-8e5d-1e0ed9ddf4c9

Feasibility of self-navigated motion resolved 3D lung MRI on a non-commercial 100 mT system

2025

Senn, N., Zihlmann, G., Sarracanie, M., Salameh, N.

Chapters in Books, Reports and Conference Proceedings: Conference Proceedings

Digital Object Identifier: https://doi.org/10.1007/s10334-025-01278-8

Divergent Morphologies and Common Signaling Features of Active and Inactive Oncogenic RHOA Mutants in Yeast

2025

Wang, C., Ohnuki, S., Savchenko, A., Aburatani, H., Yoshida, S., Hatakeyama, R., Ohya, Y.

Cells, vol. 14, no. 18, 1439

Contributions to Journals: Articles

Digital Object Identifier: https://doi.org/10.3390/cells14181439
Open Access: http://aura.abdn.ac.uk/bitstreams/0e41af28-6012-4082-9628-d7a8a7299804/download

Gut microbiota-derived short-chain fatty acids and their role in human health and disease

2025

Mukhopadhya, I., Louis, P.

Nature Reviews Microbiology, vol. 23, pp. 635-651

Contributions to Journals: Review articles

Digital Object Identifier: https://doi.org/10.1038/s41579-025-01183-w
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Monoterpenoid fluorophthalimide IMiDs that lack human cereblon binding: synthesis and anti-proliferative, anti-angiogenic and anti-inflammatory activities

2025

Luo, W., Garchitorena, K. M., Tweedie, D., Chau, C. H., Patel, C. N., Siegler, M. A., Vargesson, N., Hwang, I., Kim, S., Kim, D. S., Figg, W. D., Greig, N. H.

Biochemical and Biophysical Research Communications, vol. 779, 152428

Contributions to Journals: Articles

Digital Object Identifier: https://doi.org/10.1016/j.bbrc.2025.152428
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A key region of Tau that is able to drive assembly and modulate inhibition by Hydromethylthionine

2025

Al-Hilaly, Y. K., Rickard, J. E., Simpson, M., Storey, J. M., Harrington, C. R., Wischik, C. M., Serpell, L. C.

Journal of Molecular Biology, vol. 437, no. 17, 169231

Contributions to Journals: Articles

Digital Object Identifier: https://doi.org/10.1016/j.jmb.2025.169231
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Cell death is a conserved innate disease response of brown algae against the oomycete Eurychasma dicksonii

2025

Gachon, C. M. M., Müller, D. G., Strittmatter, M., Murua Andrade, P. F., Beckmann, M. J., Tsirigoti, A., Wawra, S., Katsaros, C. I., van West, P., Kuepper, F.

iScience, vol. 28, no. 9, 113195

Contributions to Journals: Articles

Digital Object Identifier: https://doi.org/10.1016/j.isci.2025.113195
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Insight into meiotic DNA end resection: Mechanisms and regulation

2025

Kim, S., Alnaser, H. F., Keeney, S., Murakami, H.

DNA Repair, vol. 153, 103886

Contributions to Journals: Articles

Online: https://www.sciencedirect.com/science/article/pii/S1568786425000825
Digital Object Identifier: https://doi.org/10.1016/j.dnarep.2025.103886
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Phenotypic Pharmacology of Novel Complex I Inhibitors Eliciting Tissue Repair Concurrent to Control of Inflammation

2025

Patel, L., Garcia-Raposo, F., Moore, B., Wood, J., Morley, L., Loczenski, D., Smith, S. A., Nath, P., Holliday, N., Williams, S., Greig, I. R., Vink, P., Foster, M. L.

Journal of Pharmacology and Experimental Therapeutics, vol. 392, no. 9, 103661

Contributions to Journals: Articles

Digital Object Identifier: https://doi.org/10.1016/j.jpet.2025.103661
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Proteomic and non-proteomic changes of presynaptic proteins in animal models of Alzheimer’s disease: A meta-analysis 2015-2023

2025

Anschuetz, A., Schwab, K., Harrington, C., Wischik, C., Riedel, G.

Journal of Alzheimer's Disease, vol. 107, no. 2, pp. 452-476

Contributions to Journals: Articles

Digital Object Identifier: https://doi.org/10.1177/13872877251362212
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Hydroxysteroid 17-beta dehydrogenase 13 (Hsd17b13) knockdown attenuates liver steatosis in high-fat diet obese mice

2025

Mahmood, S., Morrice, N., Thompson, D., Milanizadeh, S., Wilson, S., Whitfield, P. D., McIlroy, G. D., Rochford, J., Mody, N.

Experimental Physiology, vol. 110, no. 8, pp. 1071-1086

Contributions to Journals: Articles

Digital Object Identifier: https://doi.org/10.1113/EP092535
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Role of 18F-florzolotau PET in diagnostic and therapeutic decision-making for cognitive impairment

2025

Wang, J., Wang, Z., Chen, S., Wang, R., Chen, K., Lu, J., Xin, J., Huang, Y., Wang, M., Xie, F., Cheng, W., Yen, T., Wischik, C. M., Cui, M., Zuo, C., Zhao, Q., Wang, Y., Yu, J.

Alzheimer's & dementia : the journal of the Alzheimer's Association, vol. 21, no. 8, e70563

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Digital Object Identifier: https://doi.org/10.1002/alz.70563
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Dysregulated Alternative Splicing in Breast Cancer Subtypes of RIF1 and Other Transcripts

2025

Parker, E., Akintche, L., Pyatnitskaya, A., Hiraga, S., Donaldson, A. D.

International Journal of Molecular Sciences, vol. 26, no. 15, 7308

Contributions to Journals: Articles

Digital Object Identifier: https://doi.org/10.3390/ijms26157308
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Mannitol for cerebral oedema after acute intracerebral haemorrhage (MACE-ICH): protocol for a prospective, randomised, open-label, blinded-endpoint phase IIb trial

2025

Krishnan, K., Grace, E., Woodhouse, L., Roffe, C., Dawson, J., England, T. J., Hewson, D. W., Dineen, R. A., Law, Z. K., Pszczolkowski, S., Wells, K., Buck, A., Craig, J., Havard, D., Macleod, M. J., Werring, D. J., Doubal, F., Sprigg, N., Bath, P.

BMJ Open, vol. 15, no. 7, e103776

Contributions to Journals: Articles

Digital Object Identifier: https://doi.org/10.1136/bmjopen-2025-103776
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Additional Links: View publication in Scopus

Timing matters: early administration of a high-affinity antibody targeting the tau repeat domain prevents aggregation in a mouse tauopathy model

Effects of hydromethylthionine mesylate and rivastigmine in a pharmacological mouse model of Alzheimer's disease

Clinical, imaging and blood biomarker outcomes in a Phase 3 clinical trial of tau aggregation inhibitor hydromethylthionine mesylate in mild cognitive impairment and mild to moderate dementia due to Alzheimer’s disease

The structural basis for the selective antagonism of soluble TNF-alpha by variable new antigen receptors

Inhibiting disulphide bonding in truncated tau297-391 results in enhanced self-assembly of tau into seed-competent assemblies

Systematic gait analysis in alpha-synuclein transgenic line 62 mice using the CatWalk

Association of neighbourhood deprivation with secondary prevention prescribing and all-cause mortality among stroke patients in Scotland: a population-based study

Comparison of steroidogenic disruption in adrenal H295R and ovarian KGN and COV434 cell models and the implications to assess female reproductive toxicity

Investigation into ligand selectivity and bias at the formyl peptide receptor family

A2A Adenosine Receptor Agonists With Last-Step Enzymatic 18F-Labelling Potential (Fluorinase) for Positron Emission Tomography (PET)

Effect of the Icelandic Mutation APPA673T in the Murine APP Gene on Phenotype of Line 66 Tau Mice

Characterising interleukin-27 (IL-27) responses in human blood derived macrophage cells

Fast zero-shot deep learning-based denoising method for low-field MR images

Hyphal growth determines spatial organization and coexistence in a pathogenic polymicrobial community in a spatially structured environment

A scoping review of randomised controlled trials of vaccines that recruited care home residents: lessons for future trials

Profound cell wall remodeling in Candida parapsilosis during systemic infection confers simultaneous tolerance to echinocandins and host immunity

Physical Exercise or Cognitive Behavioral Therapy for Takotsubo Cardiomyopathy: A Randomized Controlled Trial

A comparison of T1ρ with native T1 and T2 mapping for detecting oedema in Takotsubo cardiomyopathy

Exploring the roles of conserved context-dependent cis-regulatory elements (ccdCREs) in multicellularity, human health and disease

Generation of a Ym1 Deficient Mouse utilising CRISPR-Cas9 in CB6 Embryos

How many people have a Huntington's Disease expansion: A population-based prevalence study in Northern Scotland

In vitro evolution of caspofungin resistance in Candidozyma auris via FKS1 hotspot I mutations results in moderate fitness trade-offs but no reduction in virulence

Sex-specific all-cause mortality is associated with adiposity in the Malaysian Elders Longitudinal Research (MELoR) study

Quantification of plasma tau species containing the proline-rich region as a biomarker in Alzheimer’s disease

Bioactivity Profiles of Progressively Ring-Fluorinated Cyclohexyl Motifs in the WKYMVm Peptide as Formylpeptide FPR2 Agonists and in Keto-Piperazines as Antitrypanosome Agents

Clinical care of family members of patients with dilated cardiomyopathy: a Clinical Consensus Statement of the Heart Failure Association of the ESC, the ESC Working Group on Myocardial & Pericardial Diseases, and the ESC Council on Cardiovascular Genomics

Discrimination of haematoma and peri-haematoma regions of sub-acute intracerebral haemorrhage using Field-Cycling Imaging at field strengths below 0.2 T

Stroke Diagnosis from Field-Cycling Imaging using Machine Learning

Epigenetic and Structural Brain Aging and Their Associations With Major Depressive Disorder

Identification of a regulatory sequence within the third intracellular loop that governs β-arrestin binding to the muscarinic M5 receptor

Retrospective use of the Pragmatic-Explanatory Continuum Indicator Summary-2 trial design tool to assess design choices in randomized controlled trials: an empirical review

Transdiagnostic Alterations in White Matter Microstructure Associated with Suicidal Thoughts and Behaviours in the ENIGMA Suicidal Thoughts and Behaviours Consortium

The protein-protein interaction between two spliced leader trans-splicing factors is mediated by two interlinked α-helical domains

Takotsubo syndrome: cognitive behavioural therapy, physical training, and brain function recovery in the BREAKOUT trial

Blood Biomarkers from Research Use to Clinical Practice: What Must Be Done? A Report from the EU/US CTAD Task Force

PTP1B deficiency in myeloid cells increases susceptibility to Candida albicans systemic infection by modulating antifungal immunity

The Influence of Birth Weight, Socio-Economic Status, and Adult Health on Brain Volumes during Ageing

Feasibility of self-navigated motion resolved 3D lung MRI on a non-commercial 100 mT system

Divergent Morphologies and Common Signaling Features of Active and Inactive Oncogenic RHOA Mutants in Yeast

Gut microbiota-derived short-chain fatty acids and their role in human health and disease

Monoterpenoid fluorophthalimide IMiDs that lack human cereblon binding: synthesis and anti-proliferative, anti-angiogenic and anti-inflammatory activities

A key region of Tau that is able to drive assembly and modulate inhibition by Hydromethylthionine

Cell death is a conserved innate disease response of brown algae against the oomycete Eurychasma dicksonii

Insight into meiotic DNA end resection: Mechanisms and regulation

Phenotypic Pharmacology of Novel Complex I Inhibitors Eliciting Tissue Repair Concurrent to Control of Inflammation

Proteomic and non-proteomic changes of presynaptic proteins in animal models of Alzheimer’s disease: A meta-analysis 2015-2023

Hydroxysteroid 17-beta dehydrogenase 13 (Hsd17b13) knockdown attenuates liver steatosis in high-fat diet obese mice

Role of 18F-florzolotau PET in diagnostic and therapeutic decision-making for cognitive impairment

Dysregulated Alternative Splicing in Breast Cancer Subtypes of RIF1 and Other Transcripts

Mannitol for cerebral oedema after acute intracerebral haemorrhage (MACE-ICH): protocol for a prospective, randomised, open-label, blinded-endpoint phase IIb trial

Effect of the Icelandic Mutation APP^A673T in the Murine APP Gene on Phenotype of Line 66 Tau Mice