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  • New insights into the role of CYP26 in retinoic acid clearance

    McCaffery, P.
    Expert Opinion on Drug Metabolism and Toxicology
    Contributions to Journals: Articles
    Digital Object Identifier
    https://doi.org/10.1080/17425255.2026.2664480

  • Assessment of clinical and neuroimaging efficacy of treatment targeting tau pathology in mild cognitive impairment and mild to moderate Alzheimer’s disease with hydromethylthionine mesylate using external control data

    Schelter, B. O., Shiells, H., Lo, S., Nazlee, N., Evans, E., Bentham, P., Gauthier, S., Zetterberg, H., Wilcock, G. K., Froelich, L., Burns, A., MacSweeney, E., Ballard, C., Yu, J., Choon, T. S., Asvatourian, V., Muehlemann, N., Priel, J., Kook, K., Sullivan, T., Downie, D., Miller, S., Pringle, C., Storey, J. M., Baddeley, T., Harrington, C. R., Staff, R., Sandu, A., Hull, C., Stefanacci, R., Wischik, C. M., Alzheimer's Disease Neuroimaging Initiative
    The Journal of Prevention of Alzheimer's Disease, vol. 13, no. 6, 100560
    Contributions to Journals: Articles
    Digital Object Identifier
    https://doi.org/10.1016/j.tjpad.2026.100560
    Open Access
    http://aura.abdn.ac.uk/bitstreams/d20e53ba-6471-4ae9-bf44-59d0e2633939/download

  • Rapid detection of fibrinolytic activation in postpartum hemorrhage and acute obstetric coagulopathy using a novel assay

    Ilich, A., Whyte, C. S., Moonla, C., Berkowitz, C., Pawlinski, I., Goraya, S., Lionikiene, A. S., Jenkins, P. V., de Lloyd, L., Bell, S. F., Collis, R. E., Collins, P. W., Mutch, N. J., Key, N. S.
    Blood Advances, vol. 10, no. 7, pp. 2173-2181
    Contributions to Journals: Articles
    Digital Object Identifier
    https://doi.org/10.1182/bloodadvances.2025018775

  • Atypical population pharmacokinetics of hydromethylthionine in patients with Alzheimer's disease explains unexpected phase 3 trial results

    van Maanen, E., Gonçalves, A., Chen, L., Fauchet, F., Cristea, S., Smith, J., Baddeley, T., Shiells, H., Hewitt, F., Schelter, B. O., Wischik, C. M.
    British Journal of Clinical Pharmacology
    Contributions to Journals: Articles
    Digital Object Identifier
    https://doi.org/10.1002/bcp.70539

  • Harvesting more reads from single-cell combinatorial barcoding data with scarecrow

    Morgan, M.
    Bioinformatics
    Contributions to Journals: Articles
    Digital Object Identifier
    https://doi.org/10.1093/bioinformatics/btag182

  • Cap-adjacent 2′-O-ribose methylation of RNA in C. elegans is required for postembryonic growth and germline development in the presence of the decapping exonuclease EOL-1

    Clemens, E., Brivio, S., Al-Khafaji, M. I., Eijlers, P., Kurukulasuriya, M. S., Haussmann, I. U., MacLeod, D., Wenzel, M., Muller, B., Soller, M., Pettitt, J.
    Nucleic Acids Research
    Contributions to Journals: Articles
    Digital Object Identifier
    https://doi.org/10.1093/nar/gkag355

  • A rationally designed novel bi-functional human TNF-α and Janus Kinase targeted soloMER® Drug Conjugate (SDC) with a neutrophil elastase cleavable linker delivering inflammation site-specific release of payload

    Murray, E., Priyanka, S., Martinez Fraile, J., Grygorash, R., Idress, M. S., Brownbridge, L., Glavina, S., Camper, N., Boyd, R., Porter, A., Barelle, C., Ubah, O.
    Journal of Medicinal Chemistry, vol. 69, no. 8, pp. 9664–9679
    Contributions to Journals: Articles
    Digital Object Identifier
    https://doi.org/10.1021/acs.jmedchem.6c00532
    Open Access
    http://aura.abdn.ac.uk/bitstreams/5ebb068d-8223-407e-84ab-23efa4399437/download

  • Routes to expanded carrier screening in the UK: The perspectives of professional stakeholders

    Culley, L., Herbrand, C., Hudson, N., earon, K. F., Borry, P., van Steijvoort, E., Parry, B., Norcross, S., Miedzybrodzka, Z.
    Journal of Community Genetics
    Contributions to Journals: Articles
    Digital Object Identifier
    https://doi.org/10.1007/s12687-026-00882-y

  • Fundamental limits on symmetry breaking by Turing-like activator-inhibitor mechanisms

    Hiscock, T., Muzatko, D., Daga, B.
    Development, vol. 153, no. 16, dev205067
    Contributions to Journals: Articles
    Digital Object Identifier
    https://doi.org/10.1242/dev.205067

  • Genetic counselling implementation in dilated cardiomyopathy

    Verdonschot, J. A. J., van Spaendonck-Zwarts, K. Y., Hellebrekers, D. M. E. I., Asselbergs, F. W., Behr, E. R., Charron, P., Dawson, D., Garcia-Pavia, P., Haugaa, K. H., Jurcut, R., Kuchynka, P., Lopes, L. R., Mazzanti, A., Metra, M., Monserrat, L., Kaski, J. P., Pantazis, A., Prasad, S. K., Rosano, G., Seferovic, P. M., Sheppard, M. N., Sinagra, G., Tome Esteban, M. T., Heymans, S. R. B., van Tintelen, J. P.
    European Heart Journal
    Contributions to Journals: Articles
    Digital Object Identifier
    https://doi.org/10.1093/eurheartj/ehag159

  • Sodium-glucose transporter 2 inhibition in acute takotsubo syndrome: An appealing hypothesis

    Swoboda, P. P., Dawson, D.
    International Journal of Cardiology, vol. 453, 134430
    Contributions to Journals: Articles
    Digital Object Identifier
    https://doi.org/10.1016/j.ijcard.2026.134430

  • Design and Synthesis of Dualsteric Muscarinic M5 Receptor Ligands Reveal G Protein Bias

    Steinmüller, S. A. M., Flake, A. C., Bermudez, M., Ashdown, P., Hislop, J. N., Decker, M.
    ACS Chemical Neuroscience
    Contributions to Journals: Articles
    Digital Object Identifier
    https://doi.org/10.1021/acschemneuro.6c00039

  • Novel cardiovascular metabolic risk factor mechanisms and therapeutic opportunities

    Evans, P. C., Vilahur, G., Kleinbongard, P., Osto, E., Remme, C. A., Madonna, R., Aksentijevic, D., Sourij, H., Davidson, S. M., Santovito, D., Gindlhuber, J., Weber, C., Linke, W. A., Lutgens, E., Bertrand, L., Dawson, D., Bäck, M., Norata, G. D., Wojta, J., Perrino, C.
    European Heart Journal
    Contributions to Journals: Articles
    Digital Object Identifier
    https://doi.org/10.1093/eurheartj/ehag116

  • Clinical, imaging and blood biomarker outcomes in a Phase 3 clinical trial of tau aggregation inhibitor hydromethylthionine mesylate in mild cognitive impairment and mild to moderate dementia due to Alzheimer’s disease

    Wischik, C. M., Stefanacci, R., Bentham, P., Gauthier, S., Zetterberg, H., Wilcock, G. K., Froelich, L., Burns, A., MacSweeney, E., Ballard, C., Yu, J., Choon, T. S., Asvatourian, V., Muehlemann, N., Priel, J., Kook, K., Sullivan, T., Downie, D., Miller, S., Pringle, C., Storey, J. M. D., Baddeley, T., Harrington, C. R., Penny, L. K., Arastoo, M., Staff, R., Sandu, A., Shiells, H., Lo, S., Nazlee, N., Evans, E., Hull, C., Schelter, B. O.
    The Journal of Prevention of Alzheimer's Disease, vol. 13, no. 3, 100480
    Contributions to Journals: Articles
    Online
    https://www.sciencedirect.com/science/article/pii/S227458072600004X
    Digital Object Identifier
    https://doi.org/10.1016/j.tjpad.2026.100480
    Open Access
    http://aura.abdn.ac.uk/bitstreams/75aac545-e8a2-4266-92e5-bf2b51de39fc/download

  • Baseline characteristics of patients recruited to the mannitol for cerebral oedema after acute intracerebral haemorrhage (MACE-ICH) trial

    Krishnan, K., Grace, E., Woodhouse, L., Roffe, C., Dawson, J., England, T. J., Hewson, D. W., Dineen, R. A., Law, Z. K., Pszczolkowski, S., Wells, K., Buck, A., Craig, J., Havard, D., Macleod, M. J., Werring, D. J., Doubal, F. N., Sprigg, N., Bath, P. M.
    Clinical Neurology and Neurosurgery, vol. 264, 109342
    Contributions to Journals: Articles
    Online
    https://www.sciencedirect.com/science/article/pii/S030384672600034X
    Digital Object Identifier
    https://doi.org/10.1016/j.clineuro.2026.109342

  • Profound cell wall remodeling in Candida parapsilosis during systemic infection confers simultaneous tolerance to echinocandins and host immunity

    Daneshnia, F., Cai, L., Gunasekaran, D., Gautam, I., Perry, A., Ghahfarokhy, P. M., Ebadati, A., Munoz, J., Padilla, D., Hilmioglu-Polat, S., Mei, S., Floyd, D. J., Schikora-Tamarit, M. ., Funtes, D., Artigués-Lleixà, M., Walker, L., Gonçalves, S. M., Salehi, M., Carvalho, A., Desai, J. V., Perlin, D. S., Munro, C., Hopke, A., Wang, T., Gabaldón, T., Fang, W., Nobile, C. J., Mansour, M. K., Arastehfar, A.
    Microbiology spectrum
    Contributions to Journals: Articles
    Digital Object Identifier
    https://doi.org/10.1128/spectrum.03043-25

  • Timing matters: early administration of a high-affinity antibody targeting the tau repeat domain prevents aggregation in a mouse tauopathy model

    Porter, A.
    Alzheimer's Research & Therapy
    Contributions to Journals: Articles

  • Long-read sequencing reveals increased isoform diversity in key transcription factor effectors of intercellular signalling at the invertebrate-vertebrate transition

    Torres-Aguila, N. P., Salonna, M., Shimeld, S. M., Hoppler, S., Ferrier, D. E.
    BMC Biology, vol. 24, no. 1, 28
    Contributions to Journals: Articles
    Digital Object Identifier
    https://doi.org/10.1186/s12915-026-02522-w
    Additional Links
    View publication in Scopus

  • The Effect of SERM/CB2 Receptor Modulators on Repetitive Behaviours in Juvenile and Young Adult Mice May Have Implications for Tourette Syndrome Treatment

    Gorberg, V., McCaffery, P., Anavi-Goffer, S.
    International Journal of Molecular Sciences, vol. 27, no. 3, 1181
    Contributions to Journals: Articles
    Digital Object Identifier
    https://doi.org/10.3390/ijms27031181
    Additional Links
    View publication in Scopus

  • The structural basis for the selective antagonism of soluble TNF-alpha by variable new antigen receptors

    Ubah, O., Lake, E. W., Ott, K., Priyanka, S., Celeda, S., Gunaratne, G. S., West, J., Shi, K., Moeller, N. H., Porter, A., Aihara, H., Kosoff, D., LeBeau, A. M., Barelle, C.
    Nature Communications, vol. 17, 256
    Contributions to Journals: Articles
    Digital Object Identifier
    https://doi.org/10.1038/s41467-025-66967-3
    Open Access
    http://aura.abdn.ac.uk/bitstreams/57c7ae6d-fc4e-4c8f-aeb1-0b6cf5d97be5/download

  • Inhibiting disulphide bonding in truncated tau297-391 results in enhanced self-assembly of tau into seed-competent assemblies

    Oakley, S. S., Marshall, K. E., Meisl, G., Copsey, A., Maina, M. B., Milton, R., Vorley, T., Storey, J., Harrington, C., Wischik, C., Xue, W., Serpell, L. C.
    ACS Chemical Neuroscience, vol. 17, no. 1, pp. 124-138
    Contributions to Journals: Articles
    Digital Object Identifier
    https://doi.org/10.1021/acschemneuro.5c00639
    Open Access
    http://aura.abdn.ac.uk/bitstreams/9a4ac37d-645d-4169-8d5b-f4f01f76ce49/download

  • Association of neighbourhood deprivation with secondary prevention prescribing and all-cause mortality among stroke patients in Scotland: a population-based study

    Sterling, K., Turner, M., Langhorne, P., Macleod, M.
    Cerebrovascular Diseases, vol. 55, no. 1, pp. 63-71
    Contributions to Journals: Articles
    Digital Object Identifier
    https://doi.org/10.1159/000546261
    Open Access
    http://aura.abdn.ac.uk/bitstreams/3d0b7aba-4f38-4a03-a45a-986a2ba03c86/download
    Additional Links
    View publication in Scopus

  • Comparison of steroidogenic disruption in adrenal H295R and ovarian KGN and COV434 cell models and the implications to assess female reproductive toxicity

    Vazakidou, P., Koopmans, C., Nijmeijer, S., Lecante, L. L., Liu, P., Mazaud Guittot, S., Fowler, P. A. F., Leonards, P. E., van Duursen, M. B.
    Reproductive Toxicology, vol. 139, pp. 109088
    Contributions to Journals: Articles
    Digital Object Identifier
    https://doi.org/10.1016/j.reprotox.2025.109088
    Open Access
    http://aura.abdn.ac.uk/bitstreams/3d396091-3127-40d9-a956-6615758203e9/download

  • A2A Adenosine Receptor Agonists With Last-Step Enzymatic 18F-Labelling Potential (Fluorinase) for Positron Emission Tomography (PET)

    Charalambous, N., Schleidt, C., Liu, R., Heitman, L. H., Dall’Angelo, S., O’Hagan, D., Lowe, P. T.
    European Journal of Organic Chemistry, e202501125
    Contributions to Journals: Articles
    Digital Object Identifier
    https://doi.org/10.1002/ejoc.202501125

  • Hyphal growth determines spatial organization and coexistence in a pathogenic polymicrobial community in a spatially structured environment

    Mancini, L., Saliekh, L., Claydon, R., Kotar, J., Benyei, E. B., Munro, C. A., Shendruk, T. N., Brown, A., Welch, M., Cicuta, P.
    The ISME Journal, vol. 19, no. 1, pp. wraf279
    Contributions to Journals: Articles
    Digital Object Identifier
    https://doi.org/10.1093/ismejo/wraf279
    Open Access
    http://aura.abdn.ac.uk/bitstreams/5a520a70-90d9-4170-a8ba-5fc5c6ab3d5a/download

  • A scoping review of randomised controlled trials of vaccines that recruited care home residents: lessons for future trials

    Subbarayan, S., Smith-Dodd, I., Nicolson, G., Burton, J. K., Vasan, S. S., Shenkin, S. D., Soiza, R., The WATCH Consortium, Treweek, S., Stewart, C., Macleod, M.
    Age and Ageing, vol. 54, no. 12, afaf355
    Contributions to Journals: Articles
    Digital Object Identifier
    https://doi.org/10.1093/ageing/afaf355
    Open Access
    http://aura.abdn.ac.uk/bitstreams/042377b1-a7c0-4f28-b2be-141e5228d177/download

  • Physical Exercise or Cognitive Behavioral Therapy for Takotsubo Cardiomyopathy: A Randomized Controlled Trial

    Gamble, D. T., Ross, J., Khan, H., Cheyne, L., Rudd, A., Srinivasan, J., Horgan, G., Hogg, D., Myint, P. K., Newby, D. E., Williams, C., Gray, S., Dawson, D.
    Circulation. Heart Failure
    Contributions to Journals: Articles
    Digital Object Identifier
    https://doi.org/10.1161/CIRCHEARTFAILURE.125.013229

  • Sex-specific all-cause mortality is associated with adiposity in the Malaysian Elders Longitudinal Research (MELoR) study

    Hashim, N. N. A., Mat, S., Myint, P. K., Delibegovic, M., Kioh, S. H., Bahyah Kamaruzzaman, S., Hairi, N. N., Khoo, S., Chin, A., Tan, M. P.
    Annals of Geriatric Medicine and Research, vol. 29, no. 4, pp. 496-506
    Contributions to Journals: Articles
    Digital Object Identifier
    https://doi.org/10.4235/agmr.24.0167
    Open Access
    http://aura.abdn.ac.uk/bitstreams/43c090f6-d7d1-4fd3-bfad-889af78bbc74/download
    Additional Links
    Pubmed Link
    View publication in Scopus

  • Quantification of plasma tau species containing the proline-rich region as a biomarker in Alzheimer’s disease

    Arastoo, M., Penny, L., Lofthouse, R. A., Hitchcock, A., Moelders, A. R., Szalma, S., Porter, A., Palliyil, S., Harrington, C., Wischik, C.
    Scientific Reports, vol. 15, 41881
    Contributions to Journals: Articles
    Digital Object Identifier
    https://doi.org/10.1038/s41598-025-25864-x
    Open Access
    http://aura.abdn.ac.uk/bitstreams/82867189-e587-4cae-9b66-e8593ec53c83/download
    Additional Links
    View publication in Scopus

  • Bioactivity Profiles of Progressively Ring-Fluorinated Cyclohexyl Motifs in the WKYMVm Peptide as Formylpeptide FPR2 Agonists and in Keto-Piperazines as Antitrypanosome Agents

    He, M., Thomson, C., Thompson, D., Kuodis, V., Smith, T., Dall'Angelo, S., O'hagan, D.
    ChemBioChem, vol. 26, no. 22, e202500384
    Contributions to Journals: Articles
    Digital Object Identifier
    https://doi.org/10.1002/cbic.202500384
    Open Access
    http://aura.abdn.ac.uk/bitstreams/8ec773fe-c496-471e-8896-ac88afe6b52e/download
    Additional Links
    View publication in Scopus

  • Clinical care of family members of patients with dilated cardiomyopathy: a Clinical Consensus Statement of the Heart Failure Association of the ESC, the ESC Working Group on Myocardial & Pericardial Diseases, and the ESC Council on Cardiovascular Genomics

    Verdonschot, J. A. J., Kaski, J. P., Asselbergs, F. W., Behr, E. R., Charron, P., Dawson, D., Haugaa, K. H., Kuchynka, P., Lopes, L. R., Mazzanti, A., Monserrat, L., Pantazis, A., Prasad, S. K., Schunkert, H., Seferovic, P. M., Sheppard, M. N., Sinagra, G., van Tintelen, J. P., Tome Esteban, M. T., Heymans, S. R. B., Pavia, P. G.
    European Heart Journal, vol. 46, no. 43, pp. 4569–4582
    Contributions to Journals: Articles
    Digital Object Identifier
    https://doi.org/10.1093/eurheartj/ehaf571
    Open Access
    http://aura.abdn.ac.uk/bitstreams/97db50b1-0f34-4d36-b197-baad9b1eba12/download

  • Authors' response to letter to the editor by Aierken et al. regarding "Sex differences in myocardial infarction care and outcomes a longitudinal Scottish National Data-Linkage Study"

    Pana, T. A., Mamas, M. A., Dawson, D. K.
    European Journal of Preventive Cardiology
    Contributions to Journals: Comments and Debates
    Digital Object Identifier
    https://doi.org/10.1093/eurjpc/zwaf710

  • Discrimination of haematoma and peri-haematoma regions of sub-acute intracerebral haemorrhage using Field-Cycling Imaging at field strengths below 0.2 T

    Senn, N., Mallikourti, V., Ross, J., Levi, R., Oren, N., Broche, L., Waiter, G., Macleod, M.
    UK Stroke Forum, pp. 40
    Contributions to Journals: Abstracts
    Digital Object Identifier
    https://doi.org/10.1177/17474930251379781

  • Stroke Diagnosis from Field-Cycling Imaging using Machine Learning

    Ali-Gombe, A., Senn, N., Broche, L., Mallikourti, V., Ross, J., Waiter, G., Macleod, M.
    UK Stroke Forum, pp. 41
    Contributions to Journals: Abstracts
    Digital Object Identifier
    https://doi.org/10.1177/17474930251379781

  • The protein-protein interaction between two spliced leader trans-splicing factors is mediated by two interlinked α-helical domains

    Eijlers, P., Pettitt, J., Müller, B.
    microPublication Biology, vol. 2025, 001705
    Contributions to Journals: Articles
    Online
    https://www.micropublication.org/journals/biology/micropub-biology-001705
    Digital Object Identifier
    https://doi.org/10.17912/MICROPUB.BIOLOGY.001705
    Open Access
    http://aura.abdn.ac.uk/bitstreams/974aedf5-e5ad-458c-abc2-9877796780d1/download

  • Epigenetic and Structural Brain Aging and Their Associations With Major Depressive Disorder

    Xu, E. Y., Green, C., McCartney, D. L., Han, L. K., Evans, K. L., Walker, R. M., Gadd, D. A., Steele, D., Waiter, G., Campbell, A., Lawrie, S. M., Cole, J. H., McIntosh, A. M., Shen, X., Whalley, H. C.
    Biological Psychiatry Global Open Science, vol. 5, no. 6, pp. 100577
    Contributions to Journals: Articles
    Digital Object Identifier
    https://doi.org/10.1016/j.bpsgos.2025.100577
    Open Access
    http://aura.abdn.ac.uk/bitstreams/5cf54a64-3fd3-4f73-8068-6206821ca431/download
    Additional Links
    View publication in Scopus

  • Future development of arrhythmogenic risk scores in patients with heart failure and inherited dilated cardiomyopathy. A scientific statement of the Heart Failure Association of the ESC

    Gigli, M., Verdonschot, J. A. J., Garcia-Pavia, P., Stolfo, D., Monserrat, L., Prasad, S., Mazzanti, A., Asselbergs, F. W., Bauce, B., Charron, P., Dawson, D., Halliday, B. P., Mestroni, L., Seferovic, P., Tayal, U., Esteban, M. T. T., Van Tintelen, P., Heymans, S., Pantazis, A., Metra, M., Sinagra, G.
    European Journal of Heart Failure, vol. 27, no. 11, pp. 2229-2243
    Contributions to Journals: Articles
    Digital Object Identifier
    https://doi.org/10.1002/ejhf.70042
    Additional Links
    View publication in Scopus
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