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Dr Graham Scotland

Dr Graham Scotland
Dr Graham Scotland

Dr Graham Scotland

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Biography

Graham is a Reader and leads the Assessment of Technologies theme in HERU. He joined HERU in 2004 and has since 2012 held a joint appointment between HERU and the Health Services Research Unit (HSRU). His current research interests span both model- and trial-based economic evaluation, with specific areas of interest including the evaluation of technologies in widespread routine use, the use of patient-level data to inform decision models, and the valuation of outcomes within economic evaluation. Graham graduated from the University of Edinburgh in 1998 with BSc (Hons) in pharmacology, and following this undertook an MSc in Health Services and Public Health Research at the University of Aberdeen. After completing his MSc he worked at the Dugald Baird Centre for Research in Women's Health, University of Aberdeen, where he undertook research into economic aspects of maternal healthcare delivery in developing countries. Since his appointment in HERU he has gained over 10 years’ experience working in the area of health technology assessment. In 2012 he completed a part-time PhD on methods for incorporating broader measures of value into economic evaluation in the area of reproductive healthcare.

Publications

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  • Elective freezing of embryos versus fresh embryo transfer in IVF: a multicentre randomized controlled trial in the UK (E-Freeze)

    Maheshwari, A., Bell, J. L., Bhide, P., Brison, D., Child, T., Chong, H. Y., Cheong, Y., Cole, C., Coomarasamy, A., Cutting, R., Hardy, P., Hamoda, H., Juszczak, E., Khalaf, Y., Kurinczuk, J. J., Lavery, S., Linsell, L., Macklon, N., Mathur, R., Pundir, J., Raine-Fenning, N., Rajkohwa, M., Scotland, G., Stanbury, K., Troup, S., Bhattacharya, S.
    Human reproduction (Oxford, England), vol. 37, no. 3, pp. 476-487
    Contributions to Journals: Articles

  • Pre-hospital and emergency department treatment of convulsive status epilepticus in adults: an evidence synthesis

    Cruickshank, M., Imamura, M., Booth, C., Aucott, L., Counsell, C., Manson, P., Scotland, G., Brazzelli, M.
    Health technology assessment (Winchester, England), vol. 26, no. 20, pp. 1-76
    Contributions to Journals: Articles

  • Non-invasive testing for early detection of neovascular macular degeneration in unaffected second eyes of older adults: EDNA diagnostic accuracy study

    Banister, K., Cook, J. A., Scotland, G., Azuara-Blanco, A., Goulao, B., Heimann, H., Hernández, R. A., Hogg, R. E., Kennedy, C., Sivaprasad, S., Ramsay, C., Chakravarthy, U., EDNA study group
    Health Technology Assessment, vol. 26, no. 8
    Contributions to Journals: Articles

  • Reducing asthma attacks in children using exhaled nitric oxide (RAACENO) as a biomarker to inform treatment strategy: a multicentre, parallel, randomised, controlled, phase 3 trial

    Turner, S., Cotton, S., Wood, J., Bell, V., Raja, E. A., Scott, N. W., Morgan, H., Lawrie, L., Emele, D., Kennedy, C., Scotland, G., Fielding, S., MacLennan, G., Norrie, J., Forrest, M., Gaillard, E. A., de Jongste, J., Pijnenburg, M., Thomas, M., Price, D.
    The Lancet Respiratory Medicine
    Contributions to Journals: Articles

  • Economic evaluation of Medically Assisted Reproduction: an educational overview of methods and applications for healthcare professionals

    Luyten, J., Connolly, M. P., Verbeke, E., Buhler, K., Scotland, G., Lispi, M., Revelli, A., Borget, I., Cedrin-Durnerinm, I., D’hooghe, T. M.
    Best Practice & Research Clinical Obstetrics & Gynaecology
    Contributions to Journals: Articles

  • Management of the first stage of convulsive status epilepticus in adults: a systematic review of current randomised evidence

    Cruickshank, M., Imamura, M., Counsell, C., Aucott, L., Manson, P., Booth, C., Scotland, G., Brazzelli, M.
    Journal of Neurology
    Contributions to Journals: Review articles

  • Biomarkers for assessing acute kidney injury for people who are being considered for admission to critical care: a systematic review and cost-effectiveness analysis

    Brazzelli, M., Aucott, L., Aceves Martins, M., Robertson, C., Jacobsen, E., Imamura, M., Poobalan, A., Manson, P., Scotland, G., Kaye, C., Sawhney, S., Boyers, D.
    Health Technology Assessment, vol. 26, no. 7, pp. 1-286
    Contributions to Journals: Articles

  • Cost-effectiveness and value of information analysis of NephroCheck and NGAL tests compared to standard care for the diagnosis of acute kidney injury

    Jacobsen, E., Sawhney, S., Brazzelli, M., Aucott, L., Scotland, G., Aceves Martins, M., Robertson, C., Imamura, M., Poobalan, A., Manson, P., Kaye, C., Boyers, D.
    BMC Nephrology, vol. 22, 399
    Contributions to Journals: Articles

  • Diagnostic Accuracy of Monitoring Tests of Fellow Eyes in Patients with Unilateral Neovascular Age-Related Macular Degeneration: Early Detection of Neovascular Age-Related Macular Degeneration Study

    Sivaprasad, S., Banister, K., Azuro-Blanco, A., Goulao, B., Cook, J. A., Hogg, R., Scotland, G., Heimann, H., Lotery, A., Ghanchi, F., Gale, R., Menon, G., Downey, L., Hopkins, N., Scanlon, P., Burton, B., Ramsay, C., Chakravarthy, U.
    Ophthalmology, vol. 128, no. 12, pp. 1736-1747
    Contributions to Journals: Articles

  • Assessing couples' preferences for fresh or frozen embryo transfer: a discrete choice experiment

    Abdulrahim, B., Scotland, G., Bhattacharya, S., Maheshwari, A.
    Human reproduction (Oxford, England), vol. 36, no. 11, pp. 2891-2903
    Contributions to Journals: Articles

  • A multicentre open label randomised clinical trial using exhaled nitric oxide in addition to standard care to reduce asthma attacks in children

    Turner, S., Cotton, S., Wood, J., Bell, V., Raja, E. A., Scott, N., Morgan, H., Lawrie, L., Emele, D., Kennedy, C., Scotland, G., Fielding, S., MacLennan, G., Norrie, J., Forrest, M., Gaillard, E. A., Gaillard, E. A., de Jongeste, J., Pijnenburg, M. W., Thomas, M., Price, D.
    Efficacy and Mechanism Evaluation
    Contributions to Journals: Articles

  • Early detection of neovascular age-related macular degeneration: an economic evaluation based on data from the EDNA study

    Hernández, R., Banister, K., Goulao, B., Cook, J., Sivaprasad, S., Hogg, R. E., Azuara-Blanco, A., Heimann, H., Dimitrova, M. P., Gale, R., Porteous, M., Ramsay, C., Chakravarthy, U., Scotland, G.
    British Journal of Ophthalmology
    Contributions to Journals: Articles

  • Cost-effectiveness and value of information analysis of multiple frequency bioimpedance devices for fluid management in people with chronic kidney disease having dialysis

    Jacobsen, E., Cruickshank, M., Cooper, D., Marks, A., Brazzelli, M., Scotland, G.
    Cost Effectiveness and Resource Allocation, vol. 19, 24
    Contributions to Journals: Articles

  • The Help for Hay Fever community pharmacy-based pilot randomised controlled trial for intermittent allergic rhinitis

    Smith, S., Porteous, T., Bond, C., Francis, J., Lee, A. J., Lowrie, R., Scotland, G., Sheikh, A., Thomas, M., Wyke, S., Smith, L.
    npj Primary Care Respiratory Medicine, vol. 30, pp. 23
    Contributions to Journals: Articles

  • Glyceryl trinitrate to reduce the need for manual removal of retained placenta following vaginal delivery: The GOT-IT RCT

    Denison, F. C., Carruthers, K. F., Hudson, J., McPherson, G., Scotland, G., Brook-Smith, S., Clarkson, C., Peace, M., Brewin, J., Chua, G. N., Hallowell, N., Norman, J. E., Lawton, J., Norrie, J.
    Health Technology Assessment, vol. 23, no. 70, pp. 1-72
    Contributions to Journals: Articles

  • Nitroglycerin for treatment of retained placenta: A randomised, placebo-controlled, multicentre, double-blind trial in the UK

    Denison, F., Carruthers, K. F., Hudson, J., McPherson, G., Chua, G. N., Peace, M., Brewin, J., Hallowell, N., Scotland, G., Lawton, J., Norrie, J., Norman, J. E., GOT-IT investigator team
    PLoS Medicine, vol. 16, no. 12, 1003001
    Contributions to Journals: Articles

  • Laparoscopic supracervical hysterectomy versus endometrial ablation for women with heavy menstrual bleeding (HEALTH): a parallel-group, open-label, randomised controlled trial

    Cooper, K., Breeman, S., Scott, N. W., Scotland, G., Clark, J., Hawe, J., Hawthorn, R., Phillips, K., MacLennan, G., Wileman, S., McCormack, K., Hernández, R. A., Norrie, J., Bhattacharya, S., HEALTH Study Group
    The Lancet, vol. 394, no. 10207, pp. 1425-1436
    Contributions to Journals: Articles

  • Laparoscopic supracervical hysterectomy compared with second-generation endometrial ablation for heavy menstrual bleeding: the HEALTH RCT

    Cooper, K., Breeman, S., Scott, N. W., Scotland, G. S., Hernández, R. A., Clark, T. J., Hawe, J., Hawthorn, R., Phillips, K., Wileman, S. M., McCormack, K., Norrie, J., Bhattacharya, S.
    Health Technology Assessment, vol. 23, no. 53, pp. 1-107
    Contributions to Journals: Articles

  • Five-Year Outcomes of a Randomized Trial of Treatments for Varicose Veins

    Brittenden, J., Cooper, D., Dimitrova, M., Scotland, G., Cotton, S. C., Elders, A., MacLennan, G., Ramsay, C. R., Norrie, J., Burr, J. M., Campbell, B., Bachoo, P., Chetter, I., Gough, M., Earnshaw, J., Lees, T., Scott, J., Baker, S. A., Tassie, E., Francis, J., Campbell, M. K.
    The New England Journal of Medicine, vol. 381, no. 10, pp. 912-922
    Contributions to Journals: Articles

  • Study protocol: E-freeze-freezing of embryos in assisted conception: A randomised controlled trial evaluating the clinical and cost effectiveness of a policy of freezing embryos followed by thawed frozen embryo transfer compared with a policy of fresh embryo transfer, in women undergoing in vitro fertilisation

    Maheshwari, A., Bhattacharya, S., Bowler, U., Brison, D., Child, T., Cole, C., Coomarasamy, A., Cutting, R., Harbottle, S., Hardy, P., Juszczak, E., Khalaf, Y., Kurinczuk, J. J., Lavery, S., Lewis-Jones, C., Macklon, N., Raine-Fenning, N. J., Rajkohwa, M., Scotland, G., Troup, S.
    Reproductive Health, vol. 16, 81
    Contributions to Journals: Articles

  • Dupilumab for treating adults with moderate to severe atopic dermatitis.

    Hernandez, R. A., Cruickshank, M., Dimitrova, M. P., Cooper, D. J., Aucott, L. S., Fraser, C., Shimonovich, M., Ormerod, A., Scotland, G. S., Brazzelli, M. G.
    Evidence Review Group report in support of NICE STA Programme. London: National Institute for Health and Care Excellence
    Books and Reports: Commissioned Reports

  • Multiple-frequency bioimpedance devices for fluid management in people with chronic kidney disease receiving dialysis: a systematic review and economic evaluation

    Scotland, G., Cruickshank, M., Jacobsen, E., Cooper, D., Fraser, C., Shimonovich, M., Marks, A., Brazzelli, M.
    Health Technology Assessment, vol. 22, no. 1, pp. 1-138
    Contributions to Journals: Literature Reviews

  • HEALTH: laparoscopic supracervical hysterectomy versus second-generation endometrial ablation for the treatment of heavy menstrual bleeding: study protocol for a randomised controlled trial

    Cooper, K., McCormack, K., Breeman, S., Wood, J., Scott, N. W., Clark, J., Hawe, J., Hawthorn, R., Phillips, K., Hyde, A., McDonald, A., Forrest, M., Wileman, S., Scotland, G., Norrie, J., Bhattacharya, S., HEALTH Study Group
    Trials, vol. 19, 63
    Contributions to Journals: Articles

  • A pragmatic group sequential, placebo-controlled, randomised trial to determine the effectiveness of glyceryl trinitrate for retained placenta (GOT-IT): a study protocol

    Denison, F. C., Norrie, J., Lawton, J., Norman, J. E., Scotland, G., McPherson, G. C., McDonald, A., Forrest, M., Hudson, J., Brewin, J., Peace, M., Clarkson, C., Brook-Smith, S., Morrow, S., Hallowell, N., Hodges, L., Carruthers, K. F.
    BMJ Open, vol. 7, e017134
    Contributions to Journals: Articles

  • Why do health economists promote technology adoption rather than the search for efficiency? A proposal for a change in our approach to economic evaluation in health care

    Scotland, G., Stirling, B.
    Medical Decision Making, vol. 37, no. 2, pp. 139-147
    Contributions to Journals: Articles

  • Early lens extraction with intraocular lens implantation for the treatment of primary angle closure glaucoma: An economic evaluation based on data from the EAGLE trial

    Javanbakht, M., Azuara-Blanco, A., Burr, J. M., Ramsay, C., Cooper, D., Cochran, C., Norrie, J., Scotland, G.
    BMJ Open, vol. 7, no. 1, e013254
    Contributions to Journals: Articles

  • Effectiveness of early lens extraction for the treatment of primary angle-closure glaucoma (EAGLE): a randomised controlled trial

    Azuara-Blanco, A., Burr, J., Ramsay, C., Cooper, D., Foster, P. J., Friedman, D. S., Scotland, G., Javanbakht, M., Cochran, C., Norrie, J., Eagle Study Group
    The Lancet, vol. 388, no. 10052, pp. 1389-1397
    Contributions to Journals: Articles

  • Modelling the cost-effectiveness of adopting risk stratified approaches to extended screening intervals in the national diabetic retinopathy screening programme in Scotland

    Scotland, G., McKeigue, P., Philip, S., Leese, G. P., Olson, J. A., Looker, H. C., Colhoun, H. M., Javanbakht, M.
    Diabetic Medicine, vol. 33, no. 7, pp. 886-895
    Contributions to Journals: Articles

  • Is self-monitoring an effective option for people receiving long-term vitamin K antagonist therapy? A systematic review and economic evaluation

    Sharma, P., Scotland, G., Cruickshank, M., Tassie, E., Fraser, C., Burton, C. D., Croal, B., Ramsay, C. R., Brazzelli, M. G.
    BMJ Open, vol. 5, no. 6, e007758
    Contributions to Journals: Articles

  • Assessment of diagnostic tests and the impact on decision making: self-monitoring of oral anticoagulation therapy: Oral presentation

    Sharma, P., Scotland, G. S., Cruickshank, M., Tassie, E., Fraser, C. M., Burton, C. D., Croal, B. L., Ramsay, C. R., Brazzelli, M. G.
    Contributions to Conferences: Other Contributions

  • The clinical effectiveness and cost-effectiveness of point-of-care tests (CoaguChek system, INRatio2 PT/INR monitor and ProTime Microcoagulation system) for the self-monitoring of the coagulation status of people receiving long-term vitamin K antagonist therapy, compared with standard UK practice: systematic review and economic evaluation

    Sharma, P., Scotland, G. S., Cruickshank, M., Tassie, E., Fraser, C., Burton, C. D., Croal, B., Ramsay, C. R., Brazzelli, M.
    Health Technology Assessment, vol. 19, no. 48, pp. 1-172
    Contributions to Journals: Articles

  • Clinical effectiveness and cost-effectiveness of foam sclerotherapy, endovenous laser ablation and surgery for varicose veins: results from the Comparison of LAser, Surgery and foam Sclerotherapy (CLASS) randomised controlled trial

    Brittenden, J., Cotton, S. C., Elders, A., Tassie, E., Scotland, G., Ramsay, C. R., Norrie, J., Burr, J., Francis, J., Wileman, S., Campbell, B., Bachoo, P., Chetter, I., Gough, M., Earnshaw, J., Lees, T., Scott, J., Baker, S. A., MacLennan, G., Prior, M., Bolsover, D., Campbell, M. K.
    Health Technology Assessment, vol. 19, no. 27, pp. 1-342
    Contributions to Journals: Articles

  • Patient-reported improvements in health are maintained 2 years after completing a short course of cognitive behaviour therapy, exercise or both treatments for chronic widespread pain: Long-term results from the MUSICIAN randomised controlled trial

    Beasley, M., Prescott, G. J., Scotland, G., McBeth, J., Lovell, K., Keeley, P., Hannaford, P. C., Symmons, D. P. M., Macdonald, R., Macfarlane, G. J.
    RMD Open, vol. 1, no. 1, e000026
    Contributions to Journals: Articles

  • Cost-effectiveness of ultrasound-guided foam sclerotherapy, endovenous laser ablation or surgery as treatment for primary varicose veins from the randomized CLASS trial

    Tassie, E., Scotland, G., Brittenden, J., Cotton, S. C., Elders, A., Campbell, M. K., Campbell, B., Gough, M., Burr, J. M., Ramsay, C. R., CLASS Study Team
    British Journal of Surgery, vol. 101, no. 12, pp. 1532-1540
    Contributions to Journals: Articles

  • A randomized trial comparing treatments for varicose veins

    Brittenden, J., Cotton, S. C., Elders, A., Ramsay, C. R., Norrie, J., Burr, J., Campbell, B., Bachoo, P., Chetter, I., Gough, M., Earnshaw, J., Lees, T., Scott, J., Baker, S. A., Francis, J., Tassie, E., Scotland, G., Wileman, S., Campbell, M. K.
    The New England Journal of Medicine, vol. 371, no. 13, pp. 1218-1227
    Contributions to Journals: Articles

  • Improving the cost-effectiveness of photographic screening for diabetic macular oedema: a prospective, multi-centre, UK study

    Prescott, G., Sharp, P., Goatman, K., Scotland, G., Fleming, A., Philip, S., Staff, R., Santiago, C., Borooah, S., Broadbent, D., Chong, V., Dodson, P., Harding, S., Leese, G., Megaw, R., Styles, C., Swa, K., Wharton, H., Olson, J.
    British Journal of Ophthalmology, vol. 98, no. 8, pp. 1042-1049
    Contributions to Journals: Articles

  • An assessment of the cost-effectiveness of magnetic resonance, including diffusion-weighted imaging in patients with transient ischaemic attack and minor stroke: a systematic review, meta-analysis and economic evaluation

    Wardlaw, J., Brazzelli, M., Miranda, H., Chappell, F., McNamee, P., Scotland, G. S., Quayyum, Z., Martin, D., Shuler, K., Sandercock, P., Dennis, M.
    Health Technology Assessment, vol. 18, no. 27, pp. 1-368, v-xxvi
    Contributions to Journals: Articles

  • Long-Term Results from a Randomised Controlled Trial (RCT) Of Telephone Delivered Cognitive Behaviour Therapy (TCBT) And Exercise In The Management Of Chronic Widespread Pain (CWP), And Predictors Of Treatment-Effectiveness

    Beasley, M., Prescott, G. J., Scotland, G. S., McBeth, J., Keeley, P., Lovell, K., Hannaford, P. C., McNamee, P., Symmons, D., Woby, S., Macfarlane, G.
    British Pain Society Annual Scientific Meeting 2014
    Contributions to Conferences: Abstracts

  • Association between maternal body mass index during pregnancy, short-term morbidity and increased health service costs: a population based study

    Denison, F., Norwood, P., Bhattacharya, S., Duffy, A., Mahmood, T., Morris, C., Raja, E., Norman, J., Lee, A., Scotland, G.
    BJOG-An International Journal of Obstetrics and Gynaecology, vol. 121, no. 1, pp. 72-82
    Contributions to Journals: Articles

  • Cost of fertility treatment and live birth outcome in women of different ages and BMI

    Pandey, S., McLernon, D. J., Scotland, G., Mollison, J., Wordsworth, S., Bhattacharya, S.
    Human Reproduction, vol. 29, no. 10, pp. 2199-2211
    Contributions to Journals: Articles

  • Improving the economic value of photographic screening for optical coherence tomography-detectable macular oedema: a prospective, multicentre, UK study

    Olson, J., Sharp, P., Goatman, K., Prescott, G., Scotland, G., Fleming, A., Philip, S., Santiago, C., Borooah, S., Broadbent, D., Chong, V., Dodson, P., Harding, S., Leese, G., Styles, C., Swa, K., Wharton, H.
    Health Technology Assessment, vol. 17, no. 51, pp. 1-141
    Contributions to Journals: Articles

  • 'Help for Hay Fever', a goal-focused intervention for people with intermittent allergic rhinitis, delivered in Scottish community pharmacies: study protocol for a pilot cluster randomized controlled trial

    Porteous, T., Wyke, S., Smith, S., Bond, C., Francis, J., Lee, A. J., Lowrie, R., Scotland, G., Sheikh, A., Thomas, M., Smith, L.
    Trials, vol. 14, 217
    Contributions to Journals: Articles

  • Long-Term Effects of Cognitive Behaviour Therapy and Exercise for Chronic Widespread Pain

    Beasley, M., Prescott, G., McBeth, J., Scotland, G., Lovell, K., Keeley, P., Hannaford, P., McNamee, P., Symmons, D. P. M., Woby, S., Gkazinou, C., Macfarlane, G. J.
    Annals of the Rheumatic Diseases, vol. 72, pp. 1057
    Contributions to Journals: Abstracts

  • Long-term effects of cognitive behaviour therapy and exercise for chronic widespread pain

    Beasley, M., Prescott, G., McBeth, J., Scotland, G., Lovell, K., Keeley, P., Hannaford, P., McNamee, P., Symmons, D. P. M., Woby, S., Gkazinou, C., Macfarlane, G. J.
    Annals of the Rheumatic Diseases, vol. 72, no. Suppl3, pp. 131
    Contributions to Journals: Abstracts

  • The diagnostic accuracy and cost-effectiveness of magnetic resonance spectroscopy and enhanced magnetic resonance imaging techniques in aiding the localisation of prostate abnormalities for biopsy: a systematic review and economic evaluation

    Mowatt, G., Scotland, G., Boachie, C., Cruickshank, M., Ford, J. A., Fraser, C., Kurban, L., Lam, T. B., Padhani, A. R., Royle, J., Scheenen, T. W., Tassie, E.
    Health Technology Assessment, vol. 17, no. 20, pp. 1-281
    Contributions to Journals: Articles

  • Non-pharmacological interventions to reduce the risk of diabetes in people with impaired glucose regulation: a systematic review and economic evaluation

    Gillett, M., Royle, P., Snaith, A., Scotland, G., Poobalan, A., Imamura, M., Black, C., Boroujerdi, M., Jick, S., Wyness, L., McNamee, P., Brennan, A., Waugh, N.
    Health Technology Assessment, vol. 16, no. 33, pp. 1-235
    Contributions to Journals: Articles

  • Denosumab per la prevenzione delle fratture osteoporotiche in donne in post-menopausa valutazione di tecnologia singola presso il nice

    Scotland, G., Waugh, N., Royle, P., Mcnamee, P., Henderson, R., Hollick, R.
    PharmacoEconomics - Italian Research Articles, vol. 14, no. 2, pp. 131-142
    Contributions to Journals: Articles

  • Cognitive behavior therapy, exercise, or both for treating chronic widespread pain

    McBeth, J., Prescott, G., Scotland, G., Lovell, K., Keeley, P., Hannaford, P., McNamee, P., Symmons, D. P. M., Woby, S., Gkazinou, C., Beasley, M., Macfarlane, G. J.
    JAMA Internal Medicine, vol. 172, no. 1, pp. 48-57
    Contributions to Journals: Articles

  • Denosumab for the prevention of osteoporotic fractures in post-menopausal women: A NICE single technology appraisal

    Scotland, G., Waugh, N., Royle, P., McNamee, P., Henderson, R., Hollick, R.
    Pharmacoeconomics, vol. 29, no. 11, pp. 951-961
    Contributions to Journals: Articles

  • Minimising twins in in vitro fertilisation: a modelling study assessing the costs, consequences and cost-utility of elective single versus double embryo transfer over a 20-year time horizon

    Scotland, G. S., McLernon, D., Kurinczuk, J. J., McNamee, P., Harrild, K., Lyall, H., Rajkhowa, M., Hamilton, M., Bhattacharya, S.
    BJOG-An International Journal of Obstetrics and Gynaecology, vol. 118, no. 9, pp. 1073-1083
    Contributions to Journals: Articles
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