Dr Elaina Collie-Duguid

Dr Elaina Collie-Duguid
Dr Elaina Collie-Duguid
Dr Elaina Collie-Duguid

BSc (Hons) (First Class, Brisbane, Australia, 1990), PhD (Aberdeen, 1997)

Manager, Centre for Genome Enabled Biology & Medicine

About
Email Address
e.collie-duguid@abdn.ac.uk
Telephone Number
+44 (0)1224 437958
Office Address

School of Medicine, Medical Sciences and Nutrition. Room 4.015. Polwarth Bulding. Foresterhill. Aberdeen. AB25 2ZD

and

Centre for Genome Enabled Biology and Medicine. Room G17. 23 St Machar Drive. Old Aberdeen. Aberdeen. AB24 3RY.

 

School/Department
School of Medicine, Medical Sciences and Nutrition

Biography

Elaina Collie-Duguid was awarded a first class BSc (Hons) degree in molecular biology from the University of Queensland, Brisbane, Australia in 1990. Her time as a research assistant at the Centre for Molecular Biology and Biotechnology (currently The Institute of Molecular Bioscience), University of Queensland, was followed by a period of international travel, culminating in a move to Aberdeen in 1993 to begin a PhD in molecular and cellular biology at the Rowett Research Institute. In 1996, Dr Collie-Duguid took up post as a post-doctoral scientist in the Department of Medicine and Therapeutics at the University of Aberdeen and she now heads a Cancer Medicine research group with a particular focus on breast cancer within the Cancer Biomedicine programme.

Dr Collie-Duguid manages the Centre for Genome Enabled Biology and Medicine (CGEBM) at the University of Aberdeen. CGEBM provides strategic direction and coordinated management of the University of Aberdeen’s genomics facilities and facilitates genomics enabled interdisciplinary research by provision of specialised expertise, infrastructure, training, a focal point for collaboration and information exchange and genomics services to the research community. CGEBM provides specialist services in next generation sequencing (NGS), microarrays, bioinformatics and biostatistics. CGEBM helps to drive genome focused research forward by developing and exploiting modern genomic technologies to accelerate discovery of novel approaches to improve human health, the environment and agriculture within the diverse programmes of applied translational, clinical, biomedical and biological research at the University of Aberdeen.

 

 

External Memberships

Scientific Member of the Experimental and Translational Medicine Research Committee of the Chief Scientist Office, 2009-2014

Scientific Member of the Biomedical and Therapeutics Research Committee of the Chief Scientist Office, 2005-2009.

Research

Research Overview

Dr Collie-Duguid's research interest is to understand the molecular and cellular mechanisms controlling tumorigenesis, survival of cancer patients and chemoresistance in solid tumours, with a particular focus on breast cancers.  Biomarker discovery for prediction of clinical outcomes, including response to therapy; and novel drug target identification for drug development are key elements of her translational research programme. Dr Collie-Duguid has an interest in using genomic tools to understand human disease and important biological processes.

Teaching

Teaching Responsibilities

Dr Collie-Duguid teaches on level 5 courses MB5021 Bioinformatics, MT5003 Drug Metabolism and Toxicology, and MT5515 Research Methods, level 4 PA4302 Molecular Toxicology, level 3 PA3802 Mechanisms of Disease and Principles of Chemotherapy and Intercalated BSc MB ChB teaching in Genetic variation and Bioinformatics, and provides research project supervision to level 5 MSc students in the field of genomics.  

Publications

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  • Jaundice in newborns could be an evolutionary safeguard against death from sepsis

    Collie-Duguid, E., Hold, G., Hansen, R.
    The Conversation
    Contributions to Specialist Publications: Articles
  • Adaptive response of neonatal sepsis-derived Group B Streptococcus to bilirubin

    Hansen, R., Gibson, S., De Paiva Alves, E., Goddard, M., MacLaren, A., Karcher, A. M., Berry, S., Collie-Duguid, E. S. R., El-Omar, E., Munro, M., Hold, G. L.
    Scientific Reports, vol. 8, pp. 1-10
    Contributions to Journals: Articles
  • Common and Distinctive Functions of the Hippo Effectors Taz and Yap in Skeletal Muscle Stem Cell Function

    Sun, C., De Mello, V., Mohamed, A., Quiroga, H. P. O., Garcia-Munoz, A., Al Bloshi, A., Tremblay, A. M., von Kriegsheim, A., Collie-Duguid, E., Vargesson, N., Matallanas, D., Wackerhage, H., Zammit, P. S.
    Stem Cells, vol. 35, no. 8, pp. 1958-1972
    Contributions to Journals: Articles
  • Fine mapping of genes determining extrafusal fiber properties in murine soleus muscle

    Carroll, A., Cheng, R., Collie-Duguid, E., Meharg, C., Scholz, M., Fiering, S., Fields, J., Palmer, A., Lionikas, A.
    Physiological Genomics, vol. 49, no. 3, pp. 141-150
    Contributions to Journals: Articles
  • Regulation of cellular sphingosine-1-phosphate by sphingosine kinase 1 and sphingosine-1-phopshate lyase determines chemotherapy resistance in gastroesophageal cancer

    Matula, K., Collie-Duguid, E., Murray, G., Parikh, K., Grabsch, H. I., Tan, P., Lalwani, S., Garau, R., Ong, Y., Bain, G., Dahle-Smith, A., Urquhart, G., Bielawski, J., Finnegan, M., Petty, R.
    BMC Cancer, vol. 15, 762
    Contributions to Journals: Articles
  • Tumour expression of leptin is associated with chemotherapy resistance and therapy-independent prognosis in gastro-oesophageal adenocarcinomas

    Bain, G. H., Collie-Duguid, E., Murray, G. I., Gilbert, F. J., Denison, A., McKiddie, F., Ahearn, T., Fleming, I., Leeds, J., Phull, P., Park, K., Nanthakumaran, S., Grabsch, H. I., Tan, P., Welch, A., Schweiger, L., Dahle-Smith, A., Urquhart, G., Finegan, M., Matula, K. M., Petty, R. D.
    British Journal of Cancer, vol. 110, no. 6, pp. 1525-1534
    Contributions to Journals: Articles
  • Influence of resistance to 5-fluorouracil and tomudex on [18F]-FDG incorporation, glucose transport and hexokinase activity

    Law, A. A., Collie-Duguid, E. S. R., Smith, T. A. D.
    International Journal of Oncology, vol. 41, no. 1, pp. 378-382
    Contributions to Journals: Articles
  • SerpinB3, a new prognostic tool in breast cancer patients treated with neoadjuvant chemotherapy

    Collie-Duguid, E. S. R., Sweeney, K., Stewart, K. N., Miller, I. D., Smyth, E., Heys, S. D.
    Breast Cancer Research and Treatment, vol. 132, no. 3, pp. 807-818
    Contributions to Journals: Articles
  • Optimized response prediction in esophagogastric junction adenocarcinomas (EGJAc) with combination of molecular biomarkers and FDG-PET

    Petty, R. D., Bain, G., Murray, G. I., Gilbert, F., Denison, A. R., McKiddie, F., Ahearn, T., Leeds, J., Phull, P., Park, K., Welch, A., Schweiger, L. F., Collie-Duguid, E. S. R.
    Journal of Clinical Oncology, vol. 30, no. Suppl. 4, 1
    Contributions to Journals: Abstracts
  • MAGEA tumour antigens mediate platinum cytotoxicity in NSCLC

    Collie-Duguid, E. S. R., Bissett, J. D., Petty, R. D., Nicolson, M. C., Kerr, K.
    European Journal of Cancer, vol. 8, no. 7, pp. 99-100
    Contributions to Journals: Abstracts
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