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Professor Baukje de Roos

Professor Baukje de Roos
Professor Baukje de Roos
Professor Baukje de Roos

MSc PhD

Personal Chair

Accepting PhDs

About
Email Address
b.deroos@abdn.ac.uk
Telephone Number
+44 (0)1224 438636
Office Address

Rowett Institute, University of Aberdeen, Foresterhill, Aberdeen AB25 2ZD

School/Department
School of Medicine, Medical Sciences and Nutrition
Linkedin

Biography

Baukje de Roos is an internationally recognised nutrition scientist having >25 years of experience in the design and delivery of dietary intervention studies to assess how nutrients, foods and diets affect cardiovascular health outcomes and resilience to disease development. Earlier leading work in the field of proteomics and biomarker discovery led to funding for several European research projects, a BBSRC Case studentship and an invitation to join an International Life Sciences Institute (ILSI) task force to establish the usefulness of proteomics for efficacy demonstration of dietary bioactives. Current work focusses on developing and implementing novel and state-of-the-art interdisciplinary precision and personalised nutrition approaches to improve population and individual health, as well as identifying responders and non-responders to interventions, supported by RCUK and industry funding as well as several international research collaborations. Her Scottish Government RESAS-funded work focusses on exploratory modelling of relationships between ‘healthiness’, ‘carbon footprint’, ‘level of processing’ and ‘cost’ of UK diets to identify the most important potential food switches in real-time UK diets, work which is now being developed into a ‘foodswap’ app. Her expertise in the area of diet and health has formed the basis of contracts and consultancies with large food companies (Unilever, By-Health, Stephan Nutrition, Cognis, MacPhie of Glenbervie, Provexis, Kelloggs), food levy boards (Seafish), the food and drink support sector (Food and Drink Innovation Service, Scotland Food & Drink), and national UK television (Channel 4’s Food Hospital and Superfoods series).

Qualifications

  • MSc Human Nutrition 
    1995 - Wageningen University, the Netherlands 
  • PhD Human Nutrition 
    2000 - Wageningen University, the Netherlands 

Memberships and Affiliations

Internal Memberships

Deputy Director, the Rowett Institute, School of Medicine, Medical Sciences and Nutrition

Member of the Senior Management Team of the School of Medicine, Medical Sciences and Nutrition, University of Aberdeen.

Chair of the Human Studies Management Committee at the Rowett Institute.

External Memberships

Jan 2021 -               : Editorial Board Member for the American Journal of Clinical Nutrition

Sep 2014 – Jan 2020: Director NuGO (European Nutrigenomics Organisation) 

 

Research

Research Overview

  • Clinical and dietary intervention trials assessing how diets, foods and nutrients affect disease risk and resilience to disease development
  • Personalised and precision nutrition and biomarker discovery
  • Modelling healthy, sustainable and affordable diets
  • Food systems and human health outcomes, especially in relation to sea food consumption.

Research Areas

Accepting PhDs

I am currently accepting PhDs in Nutrition and Health.

Please get in touch if you would like to discuss your research ideas further.

Email Me

Nutrition and Health

Supervising
Accepting PhDs
View Research Area

Current Research

Seafood and human health

  • Investigating the effects of traditional versus sustainable feeding regimes of farmed salmon on heart health, micronutrient status, inflammation, oxidative stress and gut health in the Scottish population (Scottish Government Rural and Environment Science and Analytical Services)
  • Development of a metric for assessing the impacts on nutrition and health of agroecosystems producing farmed seafood (Immana)
  • Strategies to balance enhanced fish consumption with sustainable fish production (BBSRC)

Modelling healthy, sustainable and affordable diets

  • Modelling foods/drinks that drive healthiness, carbon footprint and costs within UK diets to identify ‘food switches’ in real-time UK diets (Scottish Government Rural and Environment Science and Analytical Services)

 Precision nutrition

  • Modelling individual responses to healthier diets and new ways to quantify the importance of physiology and behaviour for successful dietary changes (Unilever, BBSRC)
  • Individual efficacy of anthocyanins in blueberries to affect metabolic health (ByHealth)
  • Inter-individual variation in response to consumption of plant food bioactives and determinants involved (EU COST Action POSTIVe)

Clinical and dietary intervention trials

  • Development of nutritional and exercise strategies to increase resilience and improve health outcomes (BBSRC)

 

Collaborations

  • Anne Wanders, Liesbeth Zandstra, Peter Zock (Unilever, the Netherlands)
  • Paul Fernandes (School of Biological Sciences, University of Aberdeen)
  • Lorraine Brennan (UCD, Ireland)
  • Alan Sneddon (Rowett, University of Aberdeen)
  • Dave Little, Frances Murray, Alexandra Pounds (University of Stirling)
  • Nanna Roos (University of Copenhagen)
  • Eleanor Grieve (University of Glasgow)
  • Gulshan Ara, Santhia Ireen, Tahmeed Ahmed (icddr,b, Bangladesh)
  • Abdullah-Al Mamun (Noakhali Science and Technology University, Bangladesh)
  • Christine Morand, Claudine Manach (Université Clermont Auvergne, INRA, France)
  • Felix Zhang, Jiehua Chen (ByHealth, China)
  • Niamh O'Kennedy (SIS, UK)
  • Dr Jetty Lee, Hong Kong University, China
  • Dr Vasanthi Siruguri / Dr Radhika Madhari, National Institute of Nutrition, India
  • Prof Marianne Geleijnse, Wageningen University, the Netherlands
  • Prof Anne-Marie Minihane, University of East Anglia, UK
  • Prof Zoltan Takats, Imperial College London

 

Supervision

My current supervision areas are: Nutrition and Health.

2018-2022: supervision of Tilly Potter (BBSRC DTP / Unilever PhD studentship)

2016-2021: co-supervision of Anneli Lofstedt (EASTBIO PhD studentship)

2016-2020: supervision of Teresa Grohmann (By Health-funded PhD studentship)

2015-2018: supervision of Khairun Nafisa (Malaysian Government PhD studentship)

2013-2017: supervision of Dom Partridge (BBSRC Case/SiS PhD studentship)

2011-2014: supervision of Felix Zhang (Industrial PhD studentship)

2009-2012: supervision of Eva-Maria Bachmair (Industrial PhD studentship)

2008-2011: co-supervision of Lisa Michel (BHF PhD studentship)

2007-2011: supervision of Luisa Ostertag (Rowett/IFR PhD studentship)

2007-2009: co-supervision of Vanessa Rungapamestry (Post-doctoral student from UCD)

2007-2009: supervision of Guillermo Rodriguez Guttierez (Post-doctoral fellow)

2007-2008: supervision of Katie Crosley (Post-doctoral fellow on NuGO project)

2005-2008: supervision of Yiannis Mavrommatis (Rowett PhD-studentship)

2005-2006: supervision of Jose Miguel Arbones-Mainar (Post-doctoral fellow)

Funding and Grants

2019-2023. By-Health, Dupont, AkerBiomarine and Indena. An open label parallel randomised trial to assess the effects of a MOnitored PErsonalised Diet and Supplement intervention on the remission of metabolic syndrome (MOPEDS). £174,122

2020-2021. UKIERI. UKIERI Mobility Programme: Study in India. £33,680

2020-2021. GCRF – SFC. Sustainable Intensification : Integrating Aquaculture into Food Systems. £9,800

2019-2020. MRC Development Award. Mycotoxin exposure, intestinal inflammation and childhood stunting in India. £23,915

2019-2023. MRC UK Consortium for MetAbolic Phenotyping (MAP UK). £2,138,277

2018-2022. BBSRC DTP / Unilever. Modelling individual responses to healthier diets and new ways to quantify the importance of physiology and behaviour for successful dietary changes. £144K

2017. BBSRC GCRF IAA. Introduction of health technologies to monitor dietary intake in relation to metabolic health in India. £11K

2016-2020. EASTBIO. Strategies to balance enhanced fish consumption with sustainable fish production. £70K

2016-2018. Immana-DFID Aquatic Food for Health and Nutrition (AQN): A metric for assessing the impacts on nutrition and health of agroecosystems producing farmed seafood. £250K

2016-2021. Scottish Government (part of Rowett rolling grant). ‘(Shell)fish and human health’. ~£1M

2016-2020. By Health, China. Efficacy of anthocyanins in blueberries to affect metabolic health in a Chinese/Asian population living in China and in the UK. £90K

Teaching

Teaching Responsibilities

In the past years I have led and facilitated the successful Rowett expansion in Nutrition postgraduate teaching (PGT), from the delivery of a 1-year MSc Human Nutrition programme (since 1984) to that of a portfolio of face-to-face and new on-line MSc programmes, courses, a Massive Open Online course (MOOC) and Continuing Professional Development (CPD) (‘on demand’) offerings. 

I have developed a Rowett teaching strategy that ensures that we capitalise on recent successes to ensure that we can sustain and further develop the growth of our nutrition PGT and CPD nutrition programmes and courses. I pro-actively participate in the development and delivery of on-campus lectures (Foundation of Nutrition, Nutrition & Health, Molecular Nutrition and Clinical Nutrition courses) and on-line content and discussion forums (Fundamentals of Human Nutrition and Metabolism, Clinical Nutrition for Disease Prevention, Nutrition and Health through the Life Stages courses, Food Choice and Behaviour CPD, Nutrition and Wellbeing MOOC).

Publications

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  • Assessing Scotland’s self-sufficiency of major food commodities

    Rathnayaka, S. D., Giha, C. L. R., de Roos, B.
    Chapters in Books, Reports and Conference Proceedings: Conference Proceedings

  • Wild fish consumption can balance nutrient retention in farmed fish

    Willer, D. F., Newton, R., Malcorps, W., Kok, B., Little, D., Lofstedt, A., de Roos, B., Robinson, J. P.
    Nature Food, vol. 5, no. 3, pp. 221-229
    Contributions to Journals: Articles

  • Fish as friends and food: The significance of Frank Buckland's observations and ideas for current fish consumption patterns

    de Roos, B.
    Contributions to Journals: Features

  • Consumption of foods with the highest nutritional quality, and the lowest GHGE and price, differs between socioeconomic groups in the UK population

    Aceves Martins, M., Slater, R., Craig, L., Chalmers, N., Horgan, G., Boskamp, B., de Roos, B.
    Public Health Nutrition, vol. 26, no. 12, pp. 3370-3378
    Contributions to Journals: Articles

  • Integrated aquaculture-agriculture production supports food and nutrition security in Bangladesh

    de Roos, B.
    Nature Food, vol. 4, no. 10, pp. 833-834
    Contributions to Journals: Articles

  • An analysis of household demand for fish in Scotland

    Rathnayaka, S. D., Revoredo-Giha, C. L., de Roos, B.
    Contributions to Conferences: Papers

  • Role of metabolomics in the delivery of precision nutrition

    Brennan, L., de Roos, B.
    Redox Biology, vol. 65, 102808
    Contributions to Journals: Articles

  • A grape seed and bilberry extract reduces blood pressure in individuals at risk of developing type 2 diabetes: the PRECISE study, a double-blind placebo-controlled cross-over intervention study

    Grohmann, T., Walker, A. W., Russell, W. R., Hoggard, N., Zhang, X., Horgan, G., de Roos, B.
    Frontiers in Nutrition, vol. 10, 1139880
    Contributions to Journals: Articles

  • Factors affecting the micronutrient status of adolescent girls living in complex agro-aquatic ecological zones of Bangladesh

    Ara, G., Little, D. C., Mamun, A., de Roos, B., Grieve, E., Khanam, M., Hasan, S. M. T., Ireen, S., Ali, S. D., Boitchi, A. B., Dijkhuizen, M. A., Ahmed, T., Roos, N.
    Scientific Reports, vol. 13, no. 1, 6631
    Contributions to Journals: Articles

  • Ready meals, especially those that are animal-based and cooked in an oven, have lower nutritional quality, higher greenhouse gas emissions and are more expensive than equivalent home-cooked meals

    Aceves Martins, M., Denton, P., de Roos, B.
    Public Health Nutrition, vol. 26, no. 3, pp. 531-539
    Contributions to Journals: Articles

  • Adolescent girls in aquaculture ecozones at risk of nutrient deficiency in Bangladesh development and validation of an integrated metric

    Grieve, E., Mamun, A., de Roos, B., Barman, B. K., Ara, G., Roos, N., Pounds, A., Sneddon, A. A., Murray, F., Ahmed, T., Little, D. C.
    BMC Public Health, vol. 23, no. 1, 405
    Contributions to Journals: Articles

  • Meeting report: plant-rich dietary patterns and health

    Woodside, J. V., Sun, Q., de Roos, B., Rimm, E. B., Hu, F. B., Heinen, M. M., McEvoy, C. T., Piernas, C., Scheelbeek, P. F. D., Rushton, J., Ensaff, H., Brennan, S. F., Brennan, L.
    Contributions to Journals: Conference Articles

  • Models predict change in plasma triglyceride concentrations and long-chain n-3 polyunsaturated fatty acid proportions in healthy participants after fish oil intervention

    Potter, T. I. T., Horgan, G. W., Wanders, A. J., Zandstra, E. H., Zock, P. L., Fisk, H. L., Minihane, A. M., Calder, P. C., Mathers, J. C., de Roos, B.
    Frontiers in Nutrition, vol. 9, 989716
    Contributions to Journals: Articles

  • Food-Level Analysis to Identify Dietary Choices With the Highest Nutritional Quality and Lowest Greenhouse Gas Emissions and Price

    Aceves Martins, M., Slater, R., Craig, L., Chalmers, N., Horgan, G., Boskamp, B., de Roos, B.
    Frontiers in Nutrition, vol. 9, 851826
    Contributions to Journals: Articles

  • Nutritional Quality, Environmental Impact and Cost of Ultra-Processed Foods: A UK Food-Based Analysis

    Aceves Martins, M., Slater, R., Craig, L., Chalmers, N., Horgan, G., Boskamp, B., de Roos, B.
    International Journal of Environmental Research and Public Health, vol. 19, no. 6, 3191
    Contributions to Journals: Articles

  • Less than half of the European dietary recommendations for fish consumption are satisfied by national seafood supplies

    Lofstedt, A., de Roos, B., Fernandes, P. G.
    European Journal of Nutrition, vol. 60, pp. 4219-4228
    Contributions to Journals: Articles

  • Export-Driven, Extensive Coastal Aquaculture Can Benefit Nutritionally Vulnerable People

    Mamun, A. A., Murray, F. J., Sprague, M., McAdam, B. J., Roos, N., de Roos, B., Pounds, A., Little, D. C.
    Frontiers in Sustainable Food Systems, vol. 5, 713140
    Contributions to Journals: Articles

  • Diet, blood pressure, and heart disease - precision nutrition approaches to understand response to diet and predict disease risk

    de Roos, B.
    The American Journal of Clinical Nutrition, vol. 114, no. 5, pp. 1581–1582
    Contributions to Journals: Editorials

  • The nutritional and cardiovascular health benefits of rapeseed oil-fed farmed salmon in humans are not decreased compared with those of traditionally farmed salmon: a randomized controlled trial

    de Roos, B., Wood, S., Bremner, D., Bashir, S., Betancor, M. B., Fraser, W. D., Duthie, S. J., Horgan, G. W., Sneddon, A. A.
    European Journal of Nutrition, vol. 60, pp. 2063–2075
    Contributions to Journals: Articles

  • Efficacy of Bilberry and Grape Seed Extract Supplement Interventions to Improve Glucose and Cholesterol Metabolism and Blood Pressure in Different Populations: A Systematic Review of the Literature

    Grohmann, T., Litts, C., Horgan, G., Zhang, X., Hoggard, N., Russell, W., de Roos, B.
    Nutrients, vol. 13, no. 5, 1692
    Contributions to Journals: Articles

  • Perspective: Application of N-of-1 methods in personalized nutrition research

    Potter, T., Vieira, R., de Roos, B.
    Advances in Nutrition, vol. 12, no. 3, pp. 579-589
    Contributions to Journals: Articles

  • Nutrigenomics: lessons learned and future perspectives

    Brennan, L., de Roos, B.
    American Journal of Clinical Nutrition, vol. 113, no. 3, pp. 503-516
    Contributions to Journals: Articles

  • Linkages of agroecosystems producing farmed seafood on food security, nutritional status and adolescent health in Bangladesh

    de Roos, B., Roos, N., Ara, G., Ahmed, T., Mamun, A., Sneddon, A., Murray, F., Grieve, E., Little, D. C.
    Maternal and Child Nutrition, vol. 16, no. Suppl 3, 13017
    Contributions to Journals: Articles

  • Why interindividual variation in response to consumption of plant food bioactives matters for future personalised nutrition

    Morand, C., De Roos, B., Garcia-Conesa, M. T., Gibney, E. R., Landberg, R., Manach, C., Milenkovic, D., Rodriguez-Mateos, A., Van de Wiele, T., Tomas-Barberan, F.
    Proceedings of the Nutrition Society, vol. 79, no. 2, pp. 225-235
    Contributions to Journals: Articles

  • Inter-individual Variation in Cancer and Cardiometabolic Health Outcomes in Response to Coffee Consumption: a Critical Review

    Visser, E., Geleijnse, J. M., de Roos, B.
    Molecular Nutrition & Food Research, vol. 64, no. 7, e1900479
    Contributions to Journals: Review articles

  • Factors influencing the cardiometabolic response to (poly)phenols and phytosterols: a review of the COST Action POSITIVe activities

    Gibney, E. R., Milenkovic, D., Combet, E., Ruskovska, T., Greyling, A., González-Sarrías, A., de Roos, B., Tomás-Barberán, F., Morand, C., Rodriguez-Mateos, A.
    European Journal of Nutrition, vol. 58, pp. 37-47
    Contributions to Journals: Review articles

  • Future prospects for dissecting inter-individual variability in the absorption, distribution and elimination of plant bioactives of relevance for cardiometabolic endpoints

    Landberg, R., Manach, C., Kerckhof, F., Minihane, A., Saleh, R. N. M., De Roos, B., Tomas-Barberan, F., Morand, C., Van de Wiele, T.
    European Journal of Nutrition, vol. 58, no. Suppl 2, pp. 21-36
    Contributions to Journals: Review articles

  • Linking agroecosystems producing farmed seafood with food security and health status to better address the nutritional challenges in Bangladesh

    de Roos, B., Roos, N., Mamun, A., Ahmed, T., Sneddon, A. A., Murray, F., Grieve, E., Little, D. C.
    Public Health Nutrition, vol. 22, no. 16, pp. 2941-2949
    Contributions to Journals: Articles

  • Targeting the delivery of dietary plant bioactives to those who would benefit most: from science to practical applications

    de Roos, B., Aura, A., Bronze, M., Cassidy, A., Garcia-Conesa, M. T., Gibney, E. R.
    European Journal of Nutrition, vol. 58, no. Suppl 2, pp. 65-73
    Contributions to Journals: Review articles

  • Selenium and sulphur derivatives of hydroxytyrosol: inhibition of lipid peroxidation in liver microsomes of vitamin E-deficient rats

    Rodríguez-Gutiérrez, G., Rubio-Senent, F., Gómez-Carretero, A., Maya, I., Fernández-Bolaños, J., Duthie, G. G., de Roos, B.
    European Journal of Nutrition, vol. 58, no. 5, pp. 1847-1851
    Contributions to Journals: Articles

  • Effect of nonmeat, high-protein supplementation on quality of life and clinical outcomes in older residents of care homes: a systematic review and meta-analysis

    Donaldson, A. I. C., Smith, T. O., Alder, S., Johnstone, A. M., de Roos, B., Aucott, L. S., Gordon, A. L., Myint, P. K.
    Nutrition Reviews, vol. 77, no. 2, pp. 116-127
    Contributions to Journals: Articles

  • SerpinA3N is a novel hypothalamic gene upregulated by a high-fat diet and leptin in mice

    Sergi, D., Campbell, F. M., Grant, C., Morris, A. C., Bachmair, E., Koch, C., McLean, F. H., Muller, A., Hoggard, N., de Roos, B., Porteiro, B., Boekschoten, M. V., McGillicuddy, F. C., Kahn, D., Nicol, P., Benzler, J., Mayer, C., Drew, J. E., Roche, H. M., Muller, M., Nogueiras, R., Diéguez, C., Tups, A., Williams, L. M.
    Genes & Nutrition, vol. 13, 28
    Contributions to Journals: Articles

  • Role of protein in healthy ageing

    Donaldson, A. I. C., Johnstone, A. M., de Roos, B., Myint, P. K.
    European Journal of Integrative Medicine, vol. 23, pp. 32-36
    Contributions to Journals: Articles

  • Personalised Interventions - A Precision Approach for the Next Generation of Dietary Intervention Studies

    de Roos, B., Brennan, L.
    Nutrients, vol. 9, no. 8, pp. 1-9
    Contributions to Journals: Review articles

  • The potential impact of compositional changes in farmed fish on its health-giving properties: is it time to reconsider current dietary recommendations?

    de Roos, B., Sneddon, A. A., Sprague, M., Horgan, G., Brouwer, I. A.
    Public Health Nutrition, vol. 20, no. 11, pp. 2042-2049
    Contributions to Journals: Articles

  • Addressing the inter-individual variation in response to consumption of plant food bioactives: Towards a better understanding of their role in healthy ageing and cardiometabolic risk reduction

    Manach, C., Milenkovic, D., Van de Wiele, T., Rodriguez-Mateos, A., de Roos, B., Garcia-Conesa, M. T., Landberg, R., Gibney, E. R., Heinonen, M., Tomás-Barberán, F., Morand, C.
    Molecular Nutrition & Food Research, vol. 61, no. 6, 1600557
    Contributions to Journals: Articles

  • An extra virgin olive oil-rich diet intervention ameliorates the non-alcoholic steatohepatitis induced by a high-fat "Western type" diet in mice

    Jurado-Ruiz, E., Varela, L. M., Luque, A., Berná, G., Cahuana, G., Martinez-Force, E., Gallego-Durán, R., Soria, B., de Roos, B., Gómez, M. R., Martín, F.
    Molecular Nutrition & Food Research, vol. 61, no. 3, pp. 1-12
    Contributions to Journals: Articles

  • Availability and dose response of phytophenols from a wheat bran-rich cereal product in healthy human volunteers

    Neacsu, M., McMonagle, J., Fletcher, R. J., Hulshof, T., Duncan, S. H., Scobbie, L., Duncan, G. J., Cantlay, L., Horgan, G., De Roos, B., Duthie, G. G., Russell, W. R.
    Molecular Nutrition & Food Research, vol. 61, no. 3, pp. 1-15
    Contributions to Journals: Articles

  • Differences in expenditure and amounts of fresh foods, fruits & vegetables and fish purchased in urban and rural Scotland

    De Roos, B., Binacchi, F., Whybrow, S., Sneddon, A. A.
    Public Health Nutrition, vol. 20, no. 3, pp. 524-533
    Contributions to Journals: Articles

  • Acute Consumption of Flavan-3-ol-Enriched Dark Chocolate Affects Human Endogenous Metabolism

    Ostertag, L. M., Philo, M., Colquhoun, I. J., Tapp, H. S., Saha, S., Duthie, G. G., Kemsley, E. K., de Roos, B., Kroon, P. A., Le Gall, G.
    Journal of Proteome Research, vol. 16, no. 7, pp. 2516-2526
    Contributions to Journals: Articles

  • The colonic metabolites dihydrocaffeic acid and dihydroferulic acid are more effective inhibitors of in vitro platelet activation than their phenolic precursors

    Baeza, G., Bachmair, E., Wood, S., Mateos, R., Bravo, L., De Roos, B.
    Food & Function, vol. 8, no. 3, pp. 1333-1342
    Contributions to Journals: Articles

  • Is life longer with a box of chocolates?

    Donaldson, A. I., de Roos, B., Johnstone, A. M., Myint, P. K.
    Heart, vol. 102, no. 13, pp. 990-991
    Contributions to Journals: Editorials

  • Inhibitory and synergistic effects of natural olive phenols on human platelet aggregation and lipid peroxidation of microsomes from vitamin E-deficient rats

    Rubio-Senent, F., de Roos, B., Duthie, G., Fernández-Bolaños, J., Rodríguez-Gutiérrez, G.
    European Journal of Nutrition, vol. 54, no. 8, pp. 1287-1295
    Contributions to Journals: Articles

  • Role of dietary pro-oxidants in the maintenance of health and resilience to oxidative stress

    de Roos, B., Duthie, G. G.
    Molecular Nutrition & Food Research, vol. 59, no. 7, pp. 1229-1248
    Contributions to Journals: Articles

  • Supplementation with a 9c,11t-rich conjugated linoleic acid blend shows no clear inhibitory effects on platelet function in healthy subjects at low and moderate cardiovascular risk: A randomized controlled trial

    Bachmair, E., Wood, S. G., Keizer, H. G., Horgan, G. W., Ford, I., de Roos, B.
    Molecular Nutrition & Food Research, vol. 59, no. 4, pp. 741-750
    Contributions to Journals: Articles

  • Pharmacological Blockade of Cannabinoid CB1 Receptors in Diet-Induced Obesity Regulates Mitochondrial Dihydrolipoamide Dehydrogenase in Muscle

    Arrabal, S., Lucena, M. A., Canduela, M. J., Ramos-Uriarte, A., Rivera, P., Serrano, A., Pavón, F. J., Decara, J., Vargas, A., Baixeras, E., Martín-Rufián, M., Márquez, J., Fernández-Llébrez, P., De Roos, B., Grandes, P., Rodríguez de Fonseca, F., Suárez, J.
    PloS ONE, vol. 10, no. 12, e0145244
    Contributions to Journals: Articles

  • Dietary manipulation of platelet function

    Bachmair, E. M., Ostertag, L. M., Zhang, X., De Roos, B.
    Pharmacology & Therapeutics, vol. 144, no. 2, pp. 97-113
    Contributions to Journals: Articles

  • Transcriptome analysis of peripheral blood mononuclear cells in human subjects following a 36 h fast provides evidence of effects on genes regulating inflammation, apoptosis and energy metabolism

    Elliott, R. M., de Roos, B., Duthie, S. J., Bouwman, F. G., Rubio-Aliaga, I., Crosley, L. K., Mayer, C., Polley, A. C., Heim, C., Coort, S. L., Evelo, C. T., Mulholland, F., Daniel, H., Mariman, E. C., Johnson, I. T.
    Genes & Nutrition, vol. 9, no. 6, pp. 1-11
    Contributions to Journals: Articles

  • Oat-enriched diet reduces inflammatory status assessed by circulating cell-derived microparticle concentrations in type 2 diabetes

    Zhang, X., McGeoch, S. C., Megson, I. L., MacRury, S. M., Johnstone, A. M., Abraham, P., Pearson, D. W. M., De Roos, B., Holtrop, G., O'Kennedy, N., Lobley, G. E.
    Molecular Nutrition & Food Research, vol. 58, no. 6, pp. 1322-1332
    Contributions to Journals: Articles

  • Platelet-derived microparticle count and surface molecule expression differ between subjects with and without type 2 diabetes, independently of obesity status

    Zhang, X., McGeoch, S. C., Johnstone, A. M., Holtrop, G., Sneddon, A. A., Macrury, S. M., Megson, I. L., Pearson, D. W. M., Abraham, P., De Roos, B., Lobley, G. E., O'Kennedy, N.
    Journal of Thrombosis and Thrombolysis, vol. 37, no. 4, pp. 455-463
    Contributions to Journals: Articles

  • Bound phytophenols from ready-to-eat cereals: comparison with other plant-based foods

    Neacsu, M., McMonagle, J., Fletcher, R. J., Scobbie, L., Duncan, G. J., Cantlay, L., de Roos, B., Duthie, G. G., Russell, W. R.
    Food Chemistry, vol. 141, no. 3, pp. 2880-2886
    Contributions to Journals: Articles

  • Flavan-3-ol-enriched dark chocolate and white chocolate improve acute measures of platelet function in a gender-specific way: A randomized-controlled human intervention trial

    Ostertag, L. M., Kroon, P. A., Wood, S., Horgan, G., Cienfuegos-Jovellanos, E., Saha, S., Duthie, G. G., De Roos, B.
    Molecular Nutrition & Food Research, vol. 57, no. 2, pp. 191-202
    Contributions to Journals: Articles

  • Personalised nutrition: ready for practice?

    De Roos, B.
    Proceedings of the Nutrition Society, vol. 72, no. 1, pp. 48-52
    Contributions to Journals: Articles

  • Mechanisms of Fish Oil-Modulated Inflammation and Health

    de Roos, B.
    Bioactive Food as Interventions for Arthritis and Related Inflammatory Diseases. Watson, R. R., Preedy, V. R. (eds.). Elsevier Inc, pp. 545-553, 9 pages
    Chapters in Books, Reports and Conference Proceedings: Chapters

  • Proteomic approaches to predict bioavailability of fatty acids and their influence on cancer and chronic disease prevention

    de Roos, B., Romagnolo, D. F.
    The Journal of Nutrition, vol. 142, no. 7, pp. 1370S-1376S
    Contributions to Journals: Articles

  • A key role for dietary bioactives in the prevention of atherosclerosis

    de Roos, B.
    Molecular Nutrition & Food Research, vol. 56, no. 7, pp. 1001-1002
    Contributions to Journals: Editorials

  • Alperujo extract, hydroxytyrosol, and 3,4-dihydroxyphenylglycol are bioavailable and have antioxidant properties in vitamin E-deficient rats: a proteomics and network analysis approach

    Rodríguez-Gutiérrez, G., Duthie, G. G., Wood, S., Morrice, P., Nicol, F., Reid, M., Cantlay, L. L., Kelder, T., Horgan, G., Fernández-Bolaños Guzmán, J., De Roos, B.
    Molecular Nutrition & Food Research, vol. 56, no. 7, pp. 1131-1147
    Contributions to Journals: Articles

  • Effect of supplementation with an 80:20 cis9, trans11 conjugated linoleic acid blend on the human platelet proteome

    Bachmair, E., Bots, M. L., Mennen, L. I., Kelder, T., Evelo, C. T., Horgan, G. W., Ford, I., de Roos, B.
    Molecular Nutrition & Food Research, vol. 56, no. 7, pp. 1148-1159
    Contributions to Journals: Articles

  • Fish as a dietary source of healthy long chain n-3 polyunsaturated fatty acids (LCn-3 PUFA) and vitamin D: A Review of the current literature

    De Roos, B., Sneddon, A. A., Macdonald, H. M.
    Food and Health Innovation Service
    Books and Reports: Commissioned Reports

  • Human O-sulfated metabolites of (-)-epicatechin and methyl-(-)-epicatechin are poor substrates for commercial aryl-sulfatases: Implications for studies concerned with quantifying epicatechin bioavailability

    Saha, S., Hollands, W., Needs, P. W., Ostertag, L. M., de Roos, B., Duthie, G. G., Kroon, P. A.
    Pharmacological Research, vol. 65, no. 6, pp. 592-602
    Contributions to Journals: Articles

  • Inter-organ proteomic analysis reveals insights into the molecular mechanisms underlying the anti-diabetic effects of cis-9, trans-11-conjugated linoleic acid in ob/ob mice

    Rungapamestry, V., McMonagle, J., Reynolds, C., Rucklidge, G., Reid, M., Duncan, G., Ross, K., Horgan, G., Toomey, S., Moloney, A. P., de Roos, B., Roche, H. M.
    Proteomics, vol. 12, no. 3, pp. 461-476
    Contributions to Journals: Articles

  • A diet rich in unsaturated fatty acids prevents progression toward heart failure in a rabbit model of pressure and volume overload

    Den Ruijter, H. M., Verkerk, A. O., Schumacher, C. A., Houten, S. M., Belterman, C. N. W., Baartscheer, A., Brouwer, I. A., van Bilsen, M., de Roos, B., Coronel, R.
    Circulation. Heart Failure, vol. 5, no. 3, pp. 376-384
    Contributions to Journals: Articles

  • Potential benefits of ready meal reformulation for the elderly

    Duthie, G. G., De Roos, B.
    Aberdeen: Rowett Institute of Nutrition and Health. 4 pages
    Books and Reports: Commissioned Reports

  • In vitro anti-platelet effects of simple plant-derived phenolic compounds are only found at high, non-physiological concentrations

    Ostertag, L. M., O'Kennedy, N., Horgan, G., Kroon, P. A., Duthie, G. G., de Roos, B.
    Molecular Nutrition & Food Research, vol. 55, no. 11, pp. 1624-1636
    Contributions to Journals: Articles

  • A high intake of industrial or ruminant trans fatty acids does not affect the plasma proteome in healthy men

    de Roos, B., Wanders, A. J., Wood, S., Horgan, G., Rucklige, G., Reid, M., Siebelink, E., Brouwer, I. A.
    Proteomics, vol. 11, no. 19, pp. 3928-3934
    Contributions to Journals: Articles

  • Anti-platelet effects of olive oil extract: in vitro functional and proteomic studies

    de Roos, B., Zhang, X., Rodriguez Gutierrez, G., Wood, S., Rucklidge, G. J., Reid, M. D., Duncan, G. J., Cantlay, L. L., Duthie, G. G., O'Kennedy, N.
    European Journal of Nutrition, vol. 50, no. 7, pp. 553-562
    Contributions to Journals: Articles

  • Metabolomics of prolonged fasting in humans reveals new catabolic markers

    Rubio-Aliaga, I., de Roos, B., Duthie, S. J., Crosley, L. K., Mayer, C., Horgan, G., Colquhoun, I. J., Le Gall, G., Huber, F., Kremer, W., Rychlik, M., Wopereis, S., van Ommen, B., Schmidt, G., Heim, C., Bouwman, F. G., Mariman, E. C., Mulholland, F., Johnson, I. T., Polley, A. C., Elliott, R. M., Daniel, H.
    Metabolomics, vol. 7, no. 3, pp. 375-387
    Contributions to Journals: Articles

  • Determination of 3,4-dihydroxyphenylglycol, hydroxytyrosol and tyrosol purified from olive oil by-products with HPLC in animal plasma and tissues

    Rodriguez-Gutierrez, G., Wood, S., Fernandez-Bolanos Guzman, J., Duthie, G. G., de Roos, B.
    Food Chemistry, vol. 126, no. 4, pp. 1948-1952
    Contributions to Journals: Articles

  • Alterations in hepatic one-carbon metabolism and related pathways following a high fat dietary intervention

    Rubio-Aliaga, I., De Roos, B., Sailer, M., McLoughlin, G., van Boekschoten, M., van Erk, M., Bachmair, E. M., van Schothorst, E., Keijer, J., Coort, S., Evelo, C., Gibney, M., Daniel, H., Muller, M., Kleemann, R., Brennan, L.
    Physiological Genomics, vol. 43, no. 8, pp. 408-416
    Contributions to Journals: Articles

  • 2D-electrophoresis and multiplex immunoassay proteomic analysis of different body fluids and cellular components reveal known and novel markers for extended fasting

    Bouwman, F. G., De Roos, B., Rubio-Aliaga, I., Crosley, L. K., Duthie, S. J., Mayer, C., Horgan, G., Polley, A. C., Heim, C., Coort, S. L., Evelo, C. T., Mulholland, F., Johnson, I. T., Elliott, R. M., Daniel, H., Mariman, E. C.
    BMC Medical Genomics, vol. 4, 24
    Contributions to Journals: Articles

  • Blood folate status and expression of proteins involved in immune function, inflammation, and coagulation: biochemical and proteomic changes in the plasma of humans in response to long-term synthetic folic acid supplementation

    Duthie, S. J., Horgan, G., De Roos, B., Rucklidge, G., Reid, M., Duncan, G., Pirie, L., Basten, G. P., Powers, H. J.
    Journal of Proteome Research, vol. 9, no. 4, pp. 1941-1950
    Contributions to Journals: Articles

  • Intervention with fish oil, but not with docosahexaenoic acid, results in lower levels of hepatic soluble epoxide hydrolase with time in apoE knockout mice

    Mavrommatis, Y., Ross, K., Rucklidge, G., Reid, M., Duncan, G. J., Gordon, M. J., Thies, F., Sneddon, A. A., De Roos, B.
    British Journal of Nutrition, vol. 103, no. 1, pp. 16-24
    Contributions to Journals: Articles

  • Dietary supplementation with cis-9, trans-11 conjugated linoleic acid and aortic stiffness in overweight and obese adults

    Sluijs, I., Plantinga, Y., De Roos, B., Mennen, L. I., Bots, M. L.
    The American Journal of Clinical Nutrition, vol. 91, no. 1, pp. 175-183
    Contributions to Journals: Articles

  • Impact of dietary polyphenols on human platelet function: a critical review of controlled dietary intervention studies

    Ostertag, L. M., O'Kennedy, N., Kroon, P. A., Duthie, G. G., De Roos, B.
    Molecular Nutrition & Food Research, vol. 54, no. 1, pp. 60-81
    Contributions to Journals: Literature Reviews

  • Proteomic analysis of plasma, platelets and peripheral blood mononuclear cells in nutritional intervention studies

    De Roos, B.
    Design of Human Nutrigenomics Studies. Astley, S., Penn, L. (eds.). Wageningen Academic Publishers, pp. 55-64, 10 pages
    Chapters in Books, Reports and Conference Proceedings: Chapters

  • Nutritional systems biology modeling: from molecular mechanisms to physiology

    de Graaf, A. A., Freidig, A. P., De Roos, B., Jamshidi, N., Heinemann, M., Rullmann, J. A. C., Hall, K. D., Adiels, M., van Ommen, B.
    PLoS Computational Biology , vol. 5, no. 11, e1000554
    Contributions to Journals: Literature Reviews

  • Long-chain n-3 polyunsaturated fatty acids: new insights into mechanisms relating to inflammation and coronary heart disease

    De Roos, B., Mavrommatis, Y., Brouwer, I. A.
    British Journal of Pharmacology, vol. 158, no. 2, pp. 413-428
    Contributions to Journals: Articles

  • Nutrition proteomics and biomarker discovery

    De Roos, B.
    Expert Review of Proteomics, vol. 6, no. 4, pp. 349-351
    Contributions to Journals: Editorials

  • Proteomic analysis of plasma, platelets and PBMC in nutritional intervention studies

    De Roos, B.
    Design of human nutrigenomic studies. Astley, S., Penn, L. (eds.). Wageningen Academic Publishers, pp. 55-64, 10 pages
    Chapters in Books, Reports and Conference Proceedings: Chapters

  • Attenuation of inflammation and cellular stress-related pathways maintains insulin sensitivity in obese type I interleukin-1 receptor knockout mice on a high-fat diet

    de Roos, B., Rungapamestry, V., Ross, K., Rucklidge, G., Reid, M., Duncan, G., Horgan, G., Toomey, S., Browne, J., Loscher, C. E., Mills, K. H. G., Roche, H. M.
    Proteomics, vol. 9, no. 12, pp. 3244-3256
    Contributions to Journals: Articles

  • Variation in protein levels obtained from human blood cells and biofluids for platelet, peripheral blood mononuclear cell, plasma, urine and saliva proteomics

    Crosley, L. K., Duthie, S. J., Polley, A. C., Bouwman, F. G., Heim, C., Mulholland, F., Horgan, G., Johnson, I. T., Mariman, E. C., Elliott, R. M., Daniel, H., De Roos, B.
    Genes & Nutrition, vol. 4, no. 2, pp. 95-102
    Contributions to Journals: Articles

  • The relationship between hypothalamic and hepatic response to a high-fat diet in relation to insulin sensitivity and leptin action

    De Roos, B., Bachmair, E., Boekschoten, M., Mayer, C. D., Muller, M., Williams, L.
    Journal of Diabetes, vol. 1, no. S1, pp. A70
    Contributions to Journals: Abstracts

  • Dietary fatty acids affecting hepatic metabolism and atherosclerosis: mechanisms unravelled using a proteomics approach

    Rodriguez Gutierrez, G., De Roos, B.
    Grasas y Aceites, vol. 60, no. 1, pp. 28-32
    Contributions to Journals: Literature Reviews

  • Proteomic analysis of human plasma and blood cells in nutritional studies: development of biomarkers to aid disease prevention

    De Roos, B.
    Expert Review of Proteomics, vol. 5, no. 6, pp. 819-826
    Contributions to Journals: Articles

  • The NuGO proof of principle study package: a collaborative research effort of the European Nutrigenomics Organisation

    Baccini, M., Bachmaier, E., Biggeri, A., Boekschoten, M. V., Bouwman, F. G., Brennan, L., Caesar, R., Cinti, S., Coort, S. L., Crosley, L. K., Daniel, H., Drevon, C. A., Duthie, S. J., Eijssen, L., Elliott, R. M., van Erk, M., Evelo, C., Gibney, M., Heim, C., Horgan, G. W., Johnson, I. T., Kelder, T., Kleemann, R., Kooistra, T., van Iersel, M. P., Mariman, E. C., Mayer, C., McLoughlin, G., Mueller, M., Mulholland, F., van Ommen, B., Polley, A. C., Pujos-Guillot, E., Rubio-Aliaga, I., Roche, H. M., De Roos, B., Sailer, M., Tonini, G., Williams, L., de Wit, N., NuGO PPS Team
    Genes & Nutrition, vol. 3, no. 3-4, pp. 147-151
    Contributions to Journals: Editorials

  • Hepatic Proteomics of Fat-1 Mice

    De Roos, B., Kang, J. X.
    Journal of Nutrigenetics and Nutrigenomics, vol. 1, no. 6, pp. 270-270
    Contributions to Journals: Articles

  • Proteomic methodological recommendations for studies involving human plasma, platelets, and peripheral blood mononuclear cells

    De Roos, B., Duthie, S. J., Polley, A. C. J., Mulholland, F., Bouwman, F. G., Heim, C., Rucklidge, G. J., Johnson, I. T., Mariman, E. C., Daniel, H., Elliott, R. M.
    Journal of Proteome Research, vol. 7, no. 6, pp. 2280-2290
    Contributions to Journals: Articles

  • Proteomics as a tool for the modelling of biological processes and biomarker development in nutrition research

    De Roos, B., McArdle, H. J.
    British Journal of Nutrition, vol. 99 , no. Suppl. 3, pp. S66-S71
    Contributions to Journals: Articles

  • Identification of potential serum biomarkers of inflammation and lipid modulation that are altered by fish oil supplementation in healthy volunteers

    De Roos, B., Geelen, A., Ross, K., Rucklidge, G., Reid, M., Duncan, G., Caslake, M., Horgan, G., Brouwer, I. A.
    Proteomics, vol. 8, no. 10, pp. 1965-1974
    Contributions to Journals: Articles

  • Hepatic proteomics in II-1-R1-/- mice that are resistant to obesity-induced insulin resistance following a high fat diet

    De Roos, B., Ross, K., Rucklidge, G. J., Toomey, S., Browne, J., Roche, H.
    Proceedings of the Nutrition Society, vol. 66, no. Suppl. OCA-B, 58A
    Contributions to Journals: Abstracts

  • The effects of fish oil and DHA on soluble epoxide hydrolase in apoE-/- mice

    Mavrommatis, Y. I., Thies, F., Ross, K., Gordon, M. J., McLeod, E., Sneddon, A. A., Rucklidge, G. J., Reid, M. D., Duncan, G. J., Mayer, C., Horgan, G., Arthur, J., De Roos, B.
    Proceedings of the Nutrition Society, vol. 66, no. Supplement OCA-B , 103A
    Contributions to Journals: Abstracts

  • Identification of Platelet Proteins Involved in Platelet Structure and Inflammation That Are Regulated by Fish Oil Supplementation in Healthy Volunteers

    De Roos, B., Massie, E., Ross, K., Rucklidge, G. J., Thies, F., O'Kennedy, N.
    Arteriosclerosis Thrombosis and Vascular Biology, vol. 27, no. 6, pp. e54-e54
    Contributions to Journals: Articles

  • Extra virgin oil decreases atherosclerosis despite increased hepatic fat accumulation in apolipoprotein E knockout mice: A proteomics approach

    Arbones-Mainar, J., Ross, K., Rucklidge, G. J., Reid, M. D., Duncan, G. J., Arthur, J., Horgan, G., Navarro, M. A., Charnicer, R., Arnal, C., Osada, J., De Roos, B.
    Diabetes and Vascular Disease Research, vol. 4, no. 1 Suppl. , S189
    Contributions to Journals: Abstracts

  • Hepatic proteomics in IL-1R1-/- mice that are resistant to obesity-induced insulin resistance following a high fat diet

    De Roos, B., Ross, K., Rucklidge, G. J., Toomey, S., Browne, J., Roche, H.
    Diabetes and Vascular Disease Research, vol. 4, no. 1 Suppl. , S189
    Contributions to Journals: Abstracts

  • Extra Virgin Olive Oils Increase Hepatic Fat Accumulation and Hepatic Antioxidant Protein Levels in APOE-/- Mice

    Arbones-Mainar, J. M., Ross, K., Rucklidge, G. J., Reid, M. D., Duncan, G. J., Arthur, J., Horgan, G. W., Navarro, M. A., Carnicer, R., Arnal, C., Osada, J., De Roos, B.
    Journal of Proteome Research, vol. 6, no. 10, pp. 4041-4054
    Contributions to Journals: Articles

  • Characterisation of the lipoprotein structure in the St. Thomas' Mixed Hyperlipidaemic (SMHL) rabbit

    De Roos, B., Caslake, M. J., Milliner, K., Benson, G., Suckling, K., Packard, C.
    Atherosclerosis, vol. 181, no. 1, pp. 63-68
    Contributions to Journals: Articles

  • Divergent mechanisms of cis9, trans11-and trans10, cis12-conjugated linoleic acid affecting insulin resistance and inflammation in apolipoprotein E knockout mice: a proteomics approach

    De Roos, B., Rucklidge, G. J., Reid, M. D., Ross, K., Duncan, G. J., Navarro, M. A., Arbones-Mainar, J. M., Guzman-Garcia, M. A., Osada, J., Browne, J., Loscher, C. E., Roche, H. M.
    The FASEB Journal, vol. 19, no. 9, pp. 1746-1767
    Contributions to Journals: Articles

  • Effect of long chain n-3 PUFA on endothelial activation, endothelial function and atheromatous plaque stability

    De Roos, B., Mercer, D. K., Wainwright, C., Thies, F.
    Current Nutrition and Food Science, vol. 1, no. 2, pp. 167-177
    Contributions to Journals: Articles

  • Mechanisms of dietary fatty acids in mouse models of atherosclerosis: A proteomics approcah

    De Roos, B.
    Non-textual Forms: Web Publications and Websites

  • Response of apolipoprotein E*3-Leiden transgenic mice to dietary fatty acids: combining liver proteomics with physiological data

    De Roos, B., Duivenvoorden, I., Rucklidge, G. J., Reid, M. D., Ross, K., Lamers, R. A. N., Voshol, P. J., Havekes, L. M., Teusink, B.
    The FASEB Journal, vol. 19, no. 7, pp. 813-815
    Contributions to Journals: Articles
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