Search
The School of Natural and Computing Sciences

Dr Thomas Baddeley

In this section
Dr Thomas Baddeley
Dr Thomas Baddeley
Dr Thomas Baddeley

PhD, BSc Hons

Senior Research Fellow

About
Telephone Number
+44 (0)1224 274238
School/Department
School of Natural and Computing Sciences
Linkedin
Google Scholar
Pure

North East Analytical Research (NEAR) Symposium

Link to the NEAR Symposium Website

NEAR Symposium

Qualifications

  • PhD Chemistry 
    2002 - University of Aberdeen 
  • BSc Hons Chemistry 
    1998 - University of Aberdeen 

External Memberships

  • Head of DMPK / Analytical Chemistry for TauRx Therapeutics
  • Cofounder of the North East Analytical Research (NEAR) Symposium

Latest Publications

View My Publications

Research

Research Overview

My focus is on the analytical pathways involved in pharmaceutical drug development.

  • This starts early during R and D looking at physical chemical testing of novel compounds and early analytical development to determine material purity and its impurities.
  • As the candidates progress further, bioanalytical methods, initial metabolism and material characterisation are developed.
  • Once into non clinical and clinical development validation according to ICH Q3 is required for material assays and ICH M7 for bioanalytical methods

 

 

Current Research

The development and use of new analytical methods in the study of small organic molecules undergoing clinical evaluation.

The development and use of bioanalytical methods used in clinical and non clinical studies

DMPK studies supporting novel pharmaceutical development

Past Research

The synthesis and study of novel organic compounds for use as potential drug candidates and excipients.

The study of the physical properties of novel oligosaccharides

Knowledge Exchange

Speaker at NEAR Symposium 2024 in Aberdeen

Speaker at REID bioanalytical Forum 2019, Cambridge

Speaker at INFORM 2018 in Copenhagen

 

Publications

Page 2 of 2 Results 26 to 35 of 35

  • Co-crystallised alpha- and beta-Anomers of 2,3,4,6-Tetra-acetyl-D-glucopyranose, in which the alpha- and beta-Anomers are Randomly Distributed in the Hydrogen-bonded Chains of Molecules

    Baddeley, T. C., Harrison, W. T. A., Howie, R. A., Skakle, J. M. S., Wardell, J. L.
    Journal of Chemical Crystallography, vol. 37, no. 12, pp. 853-858
    Contributions to Journals: Articles

  • A homologous series of eunicellin-based diterpenes from Acalycigorgia sp. characterised by tandem mass spectrometry

    Kyeremeh, K., Baddeley, T., Stein, B. K., Jaspars, M.
    Tetrahedron, vol. 62, pp. 8770-8778
    Contributions to Journals: Articles

  • 1,2,3,4-Tetra-O-acetyl-beta-D-glucopyranuronic acid monohydrate at 120 K and anhydrous 1,2,3,4-tetra-O-acetyl-beta-D-glucopyranose at 292 K

    Baddeley, T. C., Howie, R. A., Skakle, J. M. S., Wardell, J. L.
    Acta Crystallographica Section C, Crystal Structure Communications, vol. 61, no. 12, pp. o711-o714
    Contributions to Journals: Articles

  • Supramolecular structures of substituted a,a'-trehalose derivatives

    Baddeley, T., Wardell, J. L., Skakle, J., Low, J., Glidewell, C., Davidson, I.
    Acta Crystallographica Section B, Structural Science, vol. B60, no. 4, pp. 461-471
    Contributions to Journals: Articles

  • Disordered 2,2 ',3,3 ',4,6,6 '-hepta-O-pivaloyl-alpha,alpha '-trehalose

    Baddeley, T. C., Clow, S. M., Cox, P. J., Davidson, I. G., Murdoch, A. M., Wardell, J. L.
    Acta Crystallographica Section E: Structure Reports Online, vol. 59, pp. 753-755
    Contributions to Journals: Articles

  • Disordered 4,4 '-di-O-isobutyroyl-2,2 ',-3,3 ',6,6 '-hex-O-acetyl-alpha,alpha '-trehalose

    Baddeley, T. C., Clow, S. M., Cox, P. J., Davidson, I. G., Ryder, C., Wardell, J. L.
    Acta Crystallographica Section E: Structure Reports Online, vol. 59, pp. o848-o850
    Contributions to Journals: Articles

  • Ethyl 1,2,3,4-tetra-O-acetyl-beta-D-glucopyranuronate

    Baddeley, T. C., Davidson, I. G., Skakle, J. M. S., Wardell, J. L.
    Journal of Chemical Crystallography, vol. 33, pp. 33-38
    Contributions to Journals: Articles

  • Ditrityl alpha,alpha-trehalose hexaacetate

    Baddeley, T. C., Clow, S. M., Cox, P. J., Davidson, I. G., Howie, R. A., Wardell, J. L.
    Acta Crystallographica Section E: Structure Reports Online, vol. 58, no. 5, pp. o476-o477
    Contributions to Journals: Articles

  • 1,2,3,4-Tetra-O-acetyl-alpha-D-glucopyranuronamide

    Baddeley, T. C., Davidson, I. G., Skakle, J. M. S., Wardell, J. L.
    Acta Crystallographica Section E: Structure Reports Online, vol. 58, no. 4, pp. o447-o449
    Contributions to Journals: Articles

  • alpha,alpha-trehalose octaacetate ethyl acetate solvate

    Baddeley, T. C., Clow, S. M., Cox, P. J., McLaughlin, A. M., Wardell, J. L.
    Acta Crystallographica Section E: Structure Reports Online, vol. 57
    Contributions to Journals: Articles
Show 10 | 25 | 50 | 100 results per page

Refine

Contributions to Journals

Patents

Update