Professor M Carmen Romano

Professor M Carmen Romano

Personal Chair

Overview

Contact Details

Telephone
work +44 (0)1224 272507
Email
Address
The University of Aberdeen Office 337, Institute for Complex Systems and Mathematical Biology, Department of Physics, Meston Building, Old Aberdeen

Office 3:47, Institute of Medical Sciences, Foresterhill
Research

Research Overview

I am interested in the understanding of fundamental biological processes using theoretical approaches based on nonlinear dynamics and statistical physics and combining them with experimental data. In particular, I am interested in the process of translation or synthesis of proteins, the coupling between transcription and translation, how ribosomes, the molecular machines that manufacture proteins, are synthesised, and its relationship to the cell cycle. I am furthermore interested in the effect of combinatorial stresses in yeast, as well as the effects of different types of stress on the cell cycle.

Research Funding and Grants

SULSA studentship (modeling of translation)/ SABR grant (Combinatorial Responses In Stress Pathways)/BBSRC grant (Ribosome Traffic Flow on the mRNA as a Regulator of Cellular Protein Production)
Teaching

Teaching Responsibilities

Electromagnetism (PX3008, 3rd year Physics) and Introduction to Mathematics and Modelling of Biological Systems (SB5005, MSc in Cell and Molecular Systems Biology)

Publications

Publications 

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  • Stepping and Crowding of Molecular Motors: Statistical Kinetics from an Exclusion Process Perspective

    Ciandrini, L., Romano, M. C., Parmeggiani, A.

    Biophysical Journal, vol. 107, no. 5, pp. 1176-1184

    Contributions to Journals: Articles

  • Identifying coupling directions by recurrences

    Zou, Y., Romano, M. C., Thiel, M., Kurths, J.

    Recurrence Quantification Analysis. Webber Jr, C. L., Marwan, N. (eds.). Springer-Verlag, pp. 65-99, 35 pages

    Chapters in Books, Reports and Conference Proceedings: Chapters

  • Controlling translation elongation efficiency: tRNA regulation of ribosome flux on the mRNA

    Gorgoni, B., Marshall, E., McFarland, M. R., Romano, M. C., Stansfield, I.

    Biochemical Society Transactions, vol. 42, no. 1, pp. 160-165

    Contributions to Journals: Articles

  • Dominant-negative release factors and their effect on termination and translational recoding events

    McFarland, M. R., Romano, M. C., Stansfield, I.

    RNA UK 2014

    Contributions to Conferences: Posters

  • The wiper model: avalanche dynamics in an exclusion process

    Politi, A., Romano, M. C.

    Journal of statistical mechanics-Theory and experiment, vol. 2013, 10015

    Contributions to Journals: Articles

  • Dominant-negative release factors and their effect on termination and translational recoding events

    McFarland, M. R., Romano, M. C., Stansfield, I.

    Translation UK 2013

    Contributions to Conferences: Posters

  • A yeast tRNA mutant that causes pseudohyphal growth exhibits reduced rates of CAG codon translation

    Kemp, A., Betney, R., Ciandrini, L., Schwenger, A. C., Romano, M. C., Stansfield, I.

    Molecular Microbiology, vol. 87, no. 2, pp. 284–300

    Contributions to Journals: Articles

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