Publications | The Institute of Medical Sciences

Monoclonal antibodies targeting surface exposed epitopes of Candida albicans cell wall proteins confer in vivo protection in an infection model

2022

Palliyil, S., Mawer, M., Alwafi, S., Fogg, L., Buda de Cesare, G., Tan, T., Walker, L., MacCalllum, D., Porter, A., Munro, C.

Antimicrobial Agents and Chemotherapy, vol. 66, no. 4, e01957-21

Contributions to Journals: Articles

Digital Object Identifier: https://doi.org/10.1128/aac.01957-21
Open Access: http://aura.abdn.ac.uk/bitstreams/129550ba-1862-48b1-84cd-3f0e0b993129/download

Development of a high-throughput screening assay for small molecule inhibitors of androgen receptor splice variants

2022

Monaghan, A. E., Porter, A., Hunter, I., Morrison, A., McElroy, S., McEwan, I.

ASSAY and Drug Development Technologies, vol. 20, no. 3, pp. 111-124

Contributions to Journals: Articles

Digital Object Identifier: https://doi.org/10.1089/adt.2021.128

Structural Identification of Individual Helical Amyloid Filaments by Integration of Cryo-Electron Microscopy-Derived Maps in Comparative Morphometric Atomic Force Microscopy Image Analysis

2022

Lutter, L., Al-Hilaly, Y. K., Serpell, C. J., Tuite, M. F., Wischik, C. M., Serpell, L. C., Xue, W. F.

Journal of Molecular Biology, vol. 434, no. 7, 167466

Contributions to Journals: Articles

Digital Object Identifier: https://doi.org/10.1016/j.jmb.2022.167466
Open Access: http://aura.abdn.ac.uk/bitstreams/bf92d10c-6597-45ea-95e4-ac6e0c02758c/download
Additional Links: View publication in Scopus

Use of the oral beta blocker bisoprolol to reduce the rate of exacerbation in people with chronic obstructive pulmonary disease (COPD): a randomised controlled trial. (BICS)

2022

Cotton, S., Devereux, G., Abbas, H., Briggs, A. H., Campbell, K., Chaudhuri, R., Choudhury, G., Dawson, D., De Soyza, A., Fielding, S., Gompertz, S., Haughney, J., Lang, C. C., Lee, A., MacLennan, G., MacNee, W., McCormack, K., McMeekin, N., Mills, N. L., Morice, A., Norrie, J., Petrie, L., Price, D., Short, P., Vestbo, J., Walker, P., Wedzicha, J. A., Wilson, A., Lipworth, B. J.

Trials, vol. 23, no. 1, 307

Contributions to Journals: Articles

Digital Object Identifier: https://doi.org/10.1186/s13063-022-06226-8
Open Access: http://aura.abdn.ac.uk/bitstreams/53f42790-5f8e-4dfc-ae6e-5c3d6952be67/download

Protection of nascent DNA at stalled replication forks is mediated by phosphorylation of RIF1 intrinsically disordered region

2022

Balasubramanian, S., Andreani, M., Andrade, J. G., Saha, T., Sundaravinayagam, D., Garzón, J., Zhang, W., Popp, O., Hiraga, S., Rahjouei, A., Rosen, D. B., Mertins, P., Chait, B. T., Donaldson, A. D., Di Virgilio, M.

eLife, vol. 11, e75047

Contributions to Journals: Articles

Digital Object Identifier: https://doi.org/10.7554/eLife.75047
Open Access: http://aura.abdn.ac.uk/bitstreams/29cbf9f9-aa0e-4700-b2e5-b01167bc87ab/download

SWI/SNF and the histone chaperone Rtt106 drive expression of the Pleiotropic Drug Resistance network genes

2022

Nikolov, V., Malavia, D., Kubota, T.

Nature Communications, vol. 13, 1968

Contributions to Journals: Articles

Digital Object Identifier: https://doi.org/10.1038/s41467-022-29591-z
Open Access: http://aura.abdn.ac.uk/bitstreams/e04788a8-9d09-4b97-bc1d-a7610f91d440/download

Sequential enhancer state remodelling defines human germline competence and specification

2022

Tang, W. W. C., Castillo-Venzor, A., Gruhn, W. H., Kobayashi, T., Penfold, C. A., Morgan, M. D., Sun, D., Irie, N., Surani, M. A.

Nature Cell Biology, vol. 24, no. 4, pp. 448-460

Contributions to Journals: Articles

Digital Object Identifier: https://doi.org/10.1038/s41556-022-00878-z
Open Access: http://aura.abdn.ac.uk/bitstreams/5a58ee2d-7312-443e-9d54-ac8f71018c19/download
Additional Links: Link to AM in University of Cambridge repository

A cholinergic neuroskeletal interface promotes bone formation during postnatal growth and exercise

2022

Gadomski, S., Fielding, C., García-García, A., Korn, C., Ashraf, S., Villadiego, J., del Toro, R., Domingues, O., Skepper, J. N., Michel, T., Zimmer, J., Sendtner, R., Dillon, S., Poole, K., Holdsworth, G., Sendtner, M., Toledo-Aral, J. J., De Bari, C., McCaskie, A. W., Robey, P. G., Méndez-Ferrer, S.

Cell Stem Cell, vol. 29, no. 4, pp. 528-544.e9

Contributions to Journals: Articles

Digital Object Identifier: https://doi.org/10.1016/j.stem.2022.02.008
Open Access: http://aura.abdn.ac.uk/bitstreams/60802d7b-b0cb-4a96-9a4c-bde4a45d49b6/download

HMTM-Mediated Enhancement of Brain Bioenergetics in a Mouse Tauopathy Model Is Blocked by Chronic Administration of Rivastigmine

2022

Santos, R. X., Melis, V., Goatman, E. A., Leith, M., Baddeley, T. C., Storey, J. M., Riedel, G., Wischik, C. M., Harrington, C. R.

Biomedicines, vol. 10, no. 4, 867

Contributions to Journals: Articles

Digital Object Identifier: https://doi.org/10.3390/biomedicines10040867
Open Access: http://aura.abdn.ac.uk/bitstreams/161666d1-4323-45bc-9b3c-26c075dc2edd/download
Additional Links: View publication in Scopus

Identification of a prognostic signature in colorectal cancer using combinatorial algorithm-driven analysis

2022

Alnabulsi, A., Wang, T., Pang, W., Ionescu, M., Craig, S. G., Humphries, M. P., McCombe, K., Tellez, M. S., Alnabulsi, A., Murray, G.

Journal of pathology clinical research, vol. 8, no. 3, pp. 245-256

Contributions to Journals: Articles

Digital Object Identifier: https://doi.org/10.1002/cjp2.258
Open Access: http://aura.abdn.ac.uk/bitstreams/f9c847d1-eda4-459e-a49b-c3366c09e479/download