Professor Paul Fowler

Professor Paul Fowler
BSc Hons, PhD, FRSB

Chair in Translational Medical Sciences
Director of Institute of Medical Science

I am currently accepting PhDs in Biological and Environmental Sciences and Biomedical Sciences.

Overview
Professor Paul Fowler
Professor Paul Fowler

Contact Details


Biography

I received my BSc Hons and PhD in Zoology at the University of Aberdeen. I later moved to Obstetrics & Gynaecology, University of Aberdeen, to work on ovarian hormones and antiprogesterones.  In 2000 I moved to the Institute of Medical Sciences, University of Aberdeen as a Professor of Translational Medical Sciences and is currently the Director of the Institute of Medical Sciences in the School of Medicine, Medical Sciences & Nutrition at Aberdeen.

I have spent much of my career working on elucidating mechanisms in the regulation of reproduction and have over 140 peer-reviewed publications, book chapters and editorials. At each stage I made contributions in the use of technologies to answer reproductive questions, including: remote telemetry of body-testis temperature differentials, MRI analysis of body composition and mammary gland, phage library and protein purification techniques to investigate reproductive proteins and proteomic and microarray techniques to study fetal development and endometriosis. Since the turn of the century, my research has focused on the effects of maternal factors, environmental exposures and endocrine disruption on fetal development and subsequent health in both human and animal models. My group is one of the few to work on the normal first and second trimester human fetus and uses maternal smoking, obesity and deprivation as a model to understand how adverse in-utero environment disturbs fetal development in our own species.


Qualifications

PhD, Reproductive Biology University of Aberdeen 1986
BSc Hons, Zoology University of Aberdeen 1982

Latest Publications

  • Scientific Opinion on Flavouring Group Evaluation 203, Revision 2 (FGE.203Rev2): α,β-unsaturated aliphatic aldehydes and precursors from chemical subgroup 1.1.4 of FGE.19 with two or more conjugated double-bonds and with or without additional non-conjugated double-bonds

    Silano, V., Bolognesi, C., Castle, L., Chipman, K., Cravedi, J., Engel, K., Fowler, P., Franz, R., Grob, K., Husøy, T., Kärenlampi, S., Mennes, W., Milana, M. R., Pfaff, K., Riviere, G., Srinivasan, J., Tavares Poças, M. d. F., Tlustos, C., Wölfle, D., Zorn, H., Binderup, M., Marcon, F., Marzin, D., Mosesso, P., Anastassiadou, M., Carfì, M., Gürtler, R., EFSA Panel on Food Contact Materials, Enzymes, Flavourings and Processing Aids (CEF)

  • Six Decades of Research on Human Fetal Gonadal Steroids

    Connan-Perrot, S., Léger, T., Lelandais, P., Desdoits-Lethimonier, C., David, A., Fowler, P. A., Mazaud-Guittot, S.

  • Safety assessment of titanium dioxide (E171) as a food additive

    Younes, M., Aquilina, G., Castle, L., Engel, K., Fowler, P., Frutos Fernandez, M. J., Fürst, P., Gundert-Remy, U., Gürtler, R., Husøy, T., Manco, M., Mennes, W., Moldeus, P., Passamonti, S., Shah, R., Waalkens-Berendsen, I., Wölfle, D., Corsini, E., Cubadda, F., De Groot, D., FitzGerald, R., Gunnare, S., Gutleb, A. C., Mast, J., Mortensen, A., Oomen, A., Piersma, A., Plichta, V., Ulbrich, B., Van Loveren, H., Benford, D., Bignami, M., Bolognesi, C., Crebelli, R., Dusinska, M., Marcon, F., Nielsen, E., Schlatter, J., Vleminckx, C., Barmaz, S., Carfí, M., Civitella, C., Giarola, A., Rincon, A. M., Serafimova, R., Smeraldi, C., Tarazona, J., Tard, A., Wright, M., EFSA Panel on Food Additives and Flavourings (FAF)

  • Pubertal FGF21 deficit is central in the metabolic pathophysiology of an ovine model of polycystic ovary syndrome

    Siemienowicz, K. J., Furmanska, K., Filis, P., Talia, C., Thomas, J., Fowler, P. A., Rae, M. T., Colin Duncan, W.

  • The mammalian ovary: concerns about evaluation of prenatal environmental exposures

    Lecante, L., Lelandais, P., Mazaud Guittot, S., Fowler, P. A. F.

View all Publications

Memberships and Affiliations

Internal
  • Chair SMMSN Back-To-Work Group
  • Co-Chair University/NHS Grampian COVID-19 group
  • Chair SMSN Core Facilities Committee
  • Deputy Chair, University Research Facilities Working Group
  • regular Depute for Head of School meetings
  • IMS Equality & Diversity Group (Athena Swan)
  • REF2021 UoA1 Committee
  • University Health & Safety Committee
  • Division of Applied Medicine REF committee, 2012-2014
  • Joint Research Committee,  2011-2015
  • Division of Applied Medicine Executive Board,  2011-2015
  • Programme lead for the Cell, Developmental & Cancer Biology research programme, 2011-2015
  • European Advisory Committee, 2011-2014
  • College of Life Sciences & Medicine Graduate School Management Team, 2005-2009
  • IMS Safety Committee, 2004-2009
  • Medical Faculty Postgraduate Teaching Group, 1998-2005
  • Medical Faculty IT Group, 1996-2003
  • Medical Faculty Research Profile Editorial Board, 1994-1995
  • Medical Faculty Research Advisory Committee, 1992
External
  • Review Editor, Frontiers in Toxicology - Developmental and Reproductive Toxicology, 2020-
  • Member, Editorial Board, Molecular Human Reproduction, 2019-
  • Member, EFSA FAF (Food Additives and Flavourings) Panel, 2018-2024 https://www.efsa.europa.eu/en/panels/faf
  • Member, EFSA Flavourings Working Group, 2018-2024 https://www.efsa.europa.eu/en/food-ingredients-and-packaging/working-groups
  • Chair, EFSA Special Working Group on the evaluation of substances used to reduce microbial contamination from products of animal origin, 2018
  • Member Editorial Board, Scientific Reports, 2017-18
  • Member, Glasgow Children’s Hospital Charity Research Fund Steering Committee, 2017-20
  • Member, Panel 14 (Pathophysiology) of the French National Research Agency, 2017-2019
  • Member, Grampian Biorepository Steering Group, 2016-
  • Member, promotions committee, Norwegian University of Life Sciences, 2015-2016
  • Member Habilitation à Diriger des Recherches (HDR) Jury, University of Rennes, France, 2015
  • Member Editorial Board, Molecular & Cellular Endocrinology, 2014-
  • Member, EFSA CEF (Food Contact Materials, Enzymes, Flavourings and Processing Aids) Panel, 2014-2018 http://www.efsa.europa.eu/en/panels/fip.htm
  • Member, EFSA Flavourings Working Group, 2014-2018 http://www.efsa.europa.eu/en/fip/fipwgs.htm
  • Expert Evaluator, European Commission, 2014-
  • Vice-chair, HCERES (was AERES) research & tertiary education evaluation committee, France, 2014
  • Expert panel member, Endocrine Society & EU sponsored report & publications “Economic costs of endocrine disrupting compounds”. 2014-2016
  • Rapporteur for COST action TN1201 “genderSTE”, 2014
  • Member Editorial Board, Endocrinology, 2014-2017
  • External Examiner, taught Masters in Medical Science: Assisted Reproduction Technology, University of Nottingham, 2013-2016
  • Member, Society for Reproduction & Fertility Programme committee, 2013-2017
  • Member, AERES (now HCERES) research & tertiary education evaluation committee, France, 2013
  • Member, Promotions Panel, Technical University of Denmark, 2013
  • Named, invited, signatory of the Berlaymont Declaration on Endocrine Disruptors, http://www.brunel.ac.uk/__data/assets/pdf_file/0005/300200/The_Berlaymont_Declaration_on_Endocrine_Disrupters.pdf
  • Member, Expert Review Panel to assess applications submitted to 2012 CRACK IT Challenges
  • Member, Expert Working Group on Bisphenol A (BPA) toxicology of the European Food Safety Authority (EFSA), 2012-14 http://www.efsa.europa.eu/en/efsajournal/pub/3978.htm
  • Member, Gendered Innovations, FP7 case study panel, 2012
  • Fellow of the Royal Society of Biology, UK (FRSB), 2010
  • Member, Standing Evaluation Panel, Environmental Pollution at the Swedish Research Council Formas, 2010
  • Member, Scientific Committee, 5th Copenhagen Workshop on Endocrine Disrupters, 2009
  • Chair, Society for Reproduction & Fertility, 2009-2013
  • External Examiner, year 3 Reproductive Biology, University of Edinburgh, 2008-2013
  • External Examiner, Masters by Research (MRes), St George’s Hospital Medical School, London, 2008-2012
  • Editorial Advisory Board for Current Medicinal Chemistry, 2005-2009
  • Society for Reproduction and Fertility, Council Member, 2005-2013
  • Editorial Board of the journal Reproductive Biology & Endocrinology, 2002-2008
  • Chair, Local Organising Committee for Fertility 2003, joint meeting of BAS, BFS, SRF, 2000-2003. This conference was held in Aberdeen July 13-17 2003 and is considered to be one of the most successful Fertility conferences, with 685 delegates and £45,000 surplus
  • Society for Reproduction & Fertility, Meetings Committee, 2000-2004
  • Acted on various BFS/SRF sub-committees, including scientific referee for abstracts, poster/presentation judge and assessment of applications for the Serono/BFS Studentships etc
  • British Fertility Society Committee, 1993-1996

Prizes and Awards

FRSB, 2010

Research

Research Areas

Please get in touch if you would like to discuss your research ideas further.

Email Me

Specialisms

  • Developmental Biology
  • Endocrinology
  • Obstetrics and Gynaecology
  • Reproductive Biology
  • Toxicology

Our research specialisms are based on the Higher Education Classification of Subjects (HECoS) which is HESA open data, published under the Creative Commons Attribution 4.0 International


Research Overview

Since the breakthrough epidemiological studies of the 1980s it has been clear that adult human health is dependent upon fetal development and fetal programming (‘early life programming’). Fetal growth restriction, for example, can lead to hypertension, type 2 diabetes, obesity and cardiovascular disease in the adult. This fetal programming is also termed "Developmental Origins of Health and Disease" (DOHaD) or "Fetal Origins of Adult Disease. Dysfunctional changes in the fetus can arise through a range of mechanisms, such as:

  • maternal cigarette smoking
  • maternal obesity
  • maternal deprivation
  • maternal nutrition
  • maternal environmental pollutant exposure (such as air pollution)
  • maternal medication use

We are studying these factors primarily in the human itself, by studying fetuses aborted for non-medical reasons. This is supported by the SAFeR Study (Scottish Advanced Fetal Research study). The health trajectory of an individual offspring is likely to depend upon a range of maternal and lifestyle factors, including the chemical burden carried at birth. Fetal pollutant exposure has clear adverse effects on development but we have very little knowledge about levels of fetal exposure to “real-life” complex pollutant cocktails and developmental consequences. This fundamental lack of knowledge is a major impasse to developing strategies for reducing fetal pollutant burdens and predicting likely health outcomes. Available data is limited, and often indirect (i.e. animal models or surrogates of exposure), but all studies suggest that fetal pollutant exposure affects lifelong health outcomes and, thereby, impacts on the general economy.

As well as laboratory-based studies of the human fetus my group has also become involved in epidemiological studies in the same field. Our intention with this move is to improve linkage between the individual fetus/mother (laboratory) and population-wide (epidemiology) analyses of maternal environment/lifestyle effects on the fetus and its future health.

Our aim is to understand how maternal factors disturb human fetal development, leadiong to offspring with greater risk of adverse health outcomes.

Our objective is to identify mechanisms linking these maternal factors with sub-optimal fetal development and lifelong health burdens.

 


Current Research

Current Team

  • Dr Laetitia Lecants (post-doc)
  • Ms Chiara Talia (EU MSCA-ITN PhD student)
  • Ms Aikaterini Zafeiri (EASTBIO PhD student)
  • Dr Claire Walker(Research technician)

RECENT MEMBERS

  • Dr Pan Filis
  • Dr Natasha Walker (did her PhD in my lab funded Glasgow Children's Hospital Charity)

Recent Visiting Scientists

  • Mr Ajay Yadav, 3 months secondment as part of PROTECTED MSCA-ITN, Norwegian University of Life Sciences, Oslo, Norway
  • Ms Laetitia Lecante (3 months visit, Universite de Rennes 1, Rennes, France, PhD student)
  • Mr Glen Gauderat (3 months on Royal Society grant: Ecole Nationale Veterinaire de Toulouse, France, PhD student)
  • Ms Hanna Johansson (Technical University of Denmark, PhD student)
  • Dr Partha Roy (Indian Institute of Technology Roorkee)

Current Project Highlight

FREIA is an EU-funded project that aims to improve identification of chemicals that affect women’s health via disruption of the hormone system. Our project is called FREIA – Female Reproductive toxicity of EDCs: a human evidence-based screening and Identification Approach, after the Nordic Goddess of fertility.The FREIA project has received €6.1 million funding from the European Union’s Horizon 2020 research and innovation programme under grant agreement No. 825100 (FREIA). FREIA focused on chemicals that can disturb the endocrine sysatem, these chemicals are called "Endocrine Disrupting Compounds" (EDCs).Hormones and the endocrine system are vital for pregnancy and fetal development, making this an especially vulnerable time.

Recent plenary and invited presentations

  • Toxicants and maternal lifestyle disturb human fetal developmental programming. Society for Reproductive Investigation Annual Conference, Fetal Physiology Satellite meeting, Boston, July 2021.

  • Exposure to the complex mixture of environmental chemicals found in human biosolids. Virtual University of Michigan Symposium on Chemical Mixtures, 12 February 2021.
  • Toxicants and maternal lifestyle disturb human fetal developmental programming. Society for Reproductive Investigation Annual Conference, Fetal Physiology Satellite meeting, Vancouver, 10-14 March 2020.
  • Maternal lifestyle, endocrine disruption and the developing fetus. Vrije Universiteit Amsterdam, 19 February 2020, Amsterdam, Netherlands.
  • Fetal programming of health. Research for Psychologists. 18 September 2019, Aberdeen, UK.
  • Preparing for a healthy life – maternal lifestyle and fetal programming. Toxalim, 12 October 2018, Toulouse, France.
  • Effect of prenatal exposure to environmental toxins on female reproduction. Fertility 2018, 4-6 January 2018, Liverpool, UK.
  • Evidence for EDC involvement in reproductive dysfunction in women. Invited seminar at PhD Course in Reproductive Toxicology, Centre for Reproductive Biology in Uppsala (CRU) and Swedish Toxicological Sciences Research Centre (SWETOX), 12-16 June 2016, Uppsala, Sweden.
  • Real-world chemical mixtures disturb fetal endocrine systems and gonad development humans and animal models. Symposium: “Mixtures, medicines and diet, where now for endocrine disrupting compounds?” ECE2016: European Congress of Endocrinology, 28-31 May 2016, Munich, Germany.
  • Effects of in-utero exposure to toxicants on the fetal gonad and liver. Invited seminar, BIOSIT, combined University of Rennes, CNRS & INSERM unit, 9 November 2015, Rennes, France.
  • Sex, drugs, oestrogens and the human fetus. Invited public talk, Aberdeen Medico-Chirurgical Society, 1 October 2015, Aberdeen, UK.
  • New insights into human fetal development: endogenous oestrogens, maternal smoking and gene methylation. 8th Copenhagen Workshop of Endocrine Disrupters, 27-30 April 2015, Copenhagen, Denmark.
  • Environmental factors in sex differences and metabolism. ESE basic Endocrinology Course in reproductive Endocrinology, 18-20 February 2015, Edinburgh, UK.
  • The exposed proteome. Understanding biology and disease: the application of proteomics. University of Aberdeen Symposium, 9 December 2014, Aberdeen, UK. Regulation and dysregulation of primordial follicle formation and activation. 3rd World Congress of Reproductive Biology, 2-4 September 2014, Edinburgh, UK.
  • Environmental chemicals and fetal development. 2ieme Journee des Jeunes Chercheurs de L’IRSET, February 4th 2014, University of Rennes, France.
  • On women and sheep: making and breaking the fetal ovary. INRA, 13 December 2013, Jouy-en-Josas, France.
  • The evidence for EDC involvement in reproductive dysfunction in women. International Workshop: Endocrine Disrupting Chemicals and Female Reproduction. 5-6 November 2013, Uppsala, Sweden.
  • Environment and endocrine disruptors in fetal reproductive development.  IfLS Conference: Reproductive Biology – from gametes to systems, and between generations. 17 September 2013, Southampton, UK.
  • Effects of chemicals on reproductive development. Subspecialist Trainees in Reproductive Medicine and Surgery (STIRMAS). 27 September 2013, Cambridge, UK.
  • Human fetal reproductive development and endocrinology: effects of maternal smoking. 7th Copenhagen Workshop of Endocrine Disrupters, 28-31 May 2013, Copenhagen, Denmark.
  • Impact of endocrine-disrupting compounds (EDCs) on female reproductive health. Fertility 2013, Liverpool, January 3-5 2013.
  • Effects of exposure to environmental chemicals during pregnancy on the development of the male and female reproductive access“. 17th International Congress on Animal Reproduction (ICAR 29012) in Vancouver, British Columbia, Canada, July 29 – August 2, 2012.
  • Environmental exposure in reproductive development and function of the female. World Congress on Reproductive Biology, Cairns Australia 9-11 October 2011.
  • Environmental effects on fetal reproductive development. Australia Society of Reproductive Biology, Cairns Australia 7-9 October 2011.
  • Effects of EDCs on the human foetus: lessons from smoking. 6th Copenhagen Workshop of Endocrine Disrupters, 25-30 April 2011, Copenhagen, Denmark.
  • Maternal smoking and sewage sludge: consequences for fetal gonadal development. Centre for Reproductive Biology Special Symposium: “Endocrine disruptors and reproductive health: separating fact from fiction.” 7 March 2011, University of Edinburgh.
  • Mixtures of environmental chemicals: concentrations and effects in the fetus. Covance Environmental Risk Assessment (ERA) Symposium, 2-3 March 2011, Brussels.
  • In-utero exposures to environmental chemicals and consequences for ovarian development. Gordon Research Conference: “Environmental Endocrine Disrupters", 30 May-4 June 2010, Les Diablerets, Switzerland.
  • Environmental endocrine disruption of the ovary. 37th Nordic Congress of Obstetrics & Gynecology, 15-18 June 2010, Copenhagen, Denmark.
  • Endocrine disruptors and gonadal development.  Symposium: Environmental factors and nosology of the endocrine system, 2-4 October 2009, Athens, Greece.
  • In-utero exposure to environmental chemicals and consequences ovarian development. 5th Copenhagen Workshop of Endocrine Disrupters, 20-22 May 2009, Copenhagen, Denmark.
  • The fetal ovary as a target for disruption. Danish Society of Obstetrics & Gynaecology, 17 April 2009, Copenhagen, Denmark
  • Is the fetus under chemical attack? St George’s University London, 26 March 2009.
  • Gender bending chemicals and the mammalian fetal gonad. XXth International Congress of Zoology, Paris 26-29 August 2008.

Knowledge Exchange and Public Engagement

Public Engagement

  1. The Truth About Fetal Tissue Research”, Nature 528, 2015.
  2. Mother’s Smoking During Pregnancy Affects Baby’s DNA”, Scientific American, April 2016.
  3. “Science Unwrapped: Fertility”, /BBC Radio programme http://www.bbc.co.uk/programmes/p04vvspr and Naked Scientists podcast “Is modern life affecting fertility?” https://www.thenakedscientists.com/podcasts/naked-scientists/modern-life-reducing-our-fertility  21st March 2017.
  4. Move over testosterone, another hormone is also vital for making boys – and it doesn’t come from the testes” The Conversation 14/02/2019
  5. PODCAST: Hormones: The Inside Story. Series 1: Episode 6 https://podcasts.apple.com/gb/podcast/hormones-the-inside-story/id1538409023?i=1000501691883 . Also see https://www.yourhormones.info/podcast, Society for Endocrinology.
  6. Naked Scientists “Endocrine disruptors and fertility” BBC Radio interview & podcast, 26/02/2021 https://www.thenakedscientists.com/articles/interviews/endocrine-disruptors-and-fertility

Press Releases


Collaborations

  • Grateful thanks to Dr Stewart Rhind (James Hutton Institute, Aberdeen, Scotland) for the years of friendship and collaboration before his untimely death.

Supervision

My current supervision areas are: Biological and Environmental Sciences and Biomedical Sciences.


Research Funding and Grants

Career total = £16.5 million

selected grants:

2007-10      Wellcome Trust (080388) Effect of in-utero exposure to environmental chemicals via maternal pasture ingestion on fetal development. £426k [PI: collaboration with Macaulay, Edinburgh, Glasgow & INRA]

2008-12      European Commission FP7 (212855) Reproductive effects of environmental chemicals in females. £2,646k. (PI: collaboration with Macaulay, Edinburgh, INRA, Nottingham, Martin-Luther, Milan]

2009-11      Chief Scientist Office (CZB/4/742) Bioincubator system to model toxic effects on the human fetal testis. £62k [PI]

2014-17      MRC (L010011/1) The human fetal liver: development and response to maternal drug use. £589k [PI: collaboration with Glasgow, Edinburgh]

2014-18      MRC DTP (K501335/1) Development of the human fetal adrenal gland and effects of maternal smoking. £63k [CoI: Bellingham, Glasgow is PI]

2016-19      Glasgow Children’s Hospital Charity (YRSS/PHD/2016/05) Maternal smoking, drinking and deprivation: when and how of placental damage. £60k [PI: collaboration with Glasgow]

2017-21      European Commission H2020 MSCA-ITN (722634) PROTECTion against Endocrine Disruptors; detection, mixtures, health effects, risk assessment and communication. £3,152k [CoI: Connolly Queen’s Belfast is PI]

2017-20      MRC (L011535/1) Sex-specific disease aetiology from developmental steroid insults: mechanistic understanding and biomarker development towards disease prevention. £637k [CoI: Rae, Edinburgh is PI]

2017-21      BBSRC EASTBIO DTP Mechanisms via which the human fetus is at risk from over-the-counter analgesics. £97k [PI: collaboration with Edinburgh]

2018-21      Arthritis Research UK (21800) Unlocking the joint morphogenetic code in mesenchymal stem cells from human synovium. £328k [CoI: De Bari is PI]

2019-24      European Commission H2020 (825100) Female Reproductive toxicity of Endocrine disrupting chemicals (EDCs): a human evidence-based screening and Identification Approach. £5,217k [CoI: van Duursen, VU Amsterdam, is PI]

Teaching

Courses


Teaching Responsibilities

Honours and MSc students undertake research projects in my lab.


Non-Course Teaching Responsibilities

I usually have 9 tutees at any one time.

Publications

Publications 

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  • Scientific Opinion on Flavouring Group Evaluation 203, Revision 2 (FGE.203Rev2): α,β-unsaturated aliphatic aldehydes and precursors from chemical subgroup 1.1.4 of FGE.19 with two or more conjugated double-bonds and with or without additional non-conjugated double-bonds

    Silano, V., Bolognesi, C., Castle, L., Chipman, K., Cravedi, J., Engel, K., Fowler, P., Franz, R., Grob, K., Husøy, T., Kärenlampi, S., Mennes, W., Milana, M. R., Pfaff, K., Riviere, G., Srinivasan, J., Tavares Poças, M. d. F., Tlustos, C., Wölfle, D., Zorn, H., Binderup, M., Marcon, F., Marzin, D., Mosesso, P., Anastassiadou, M., Carfì, M., Gürtler, R., EFSA Panel on Food Contact Materials, Enzymes, Flavourings and Processing Aids (CEF)

    EFSA Journal, vol. 16, pp. e05322

    Contributions to Specialist Publications: Articles

  • Safety assessment of titanium dioxide (E171) as a food additive

    Younes, M., Aquilina, G., Castle, L., Engel, K., Fowler, P., Frutos Fernandez, M. J., Fürst, P., Gundert-Remy, U., Gürtler, R., Husøy, T., Manco, M., Mennes, W., Moldeus, P., Passamonti, S., Shah, R., Waalkens-Berendsen, I., Wölfle, D., Corsini, E., Cubadda, F., De Groot, D., FitzGerald, R., Gunnare, S., Gutleb, A. C., Mast, J., Mortensen, A., Oomen, A., Piersma, A., Plichta, V., Ulbrich, B., Van Loveren, H., Benford, D., Bignami, M., Bolognesi, C., Crebelli, R., Dusinska, M., Marcon, F., Nielsen, E., Schlatter, J., Vleminckx, C., Barmaz, S., Carfí, M., Civitella, C., Giarola, A., Rincon, A. M., Serafimova, R., Smeraldi, C., Tarazona, J., Tard, A., Wright, M., EFSA Panel on Food Additives and Flavourings (FAF)

    EFSA Journal, vol. 19, no. 5, e06585

    Contributions to Journals: Articles

  • Pubertal FGF21 deficit is central in the metabolic pathophysiology of an ovine model of polycystic ovary syndrome

    Siemienowicz, K. J., Furmanska, K., Filis, P., Talia, C., Thomas, J., Fowler, P. A., Rae, M. T., Colin Duncan, W.

    Molecular and Cellular Endocrinology, vol. 525, 111196

    Contributions to Journals: Articles

  • The mammalian ovary: concerns about evaluation of prenatal environmental exposures

    Lecante, L., Lelandais, P., Mazaud Guittot, S., Fowler, P. A. F.

    Current Opinion in Endocrine and Metabolic Research

    Contributions to Journals: Review articles

  • Scientific Guidance for the preparation of applications on smoke flavouring primary products

    (FAF), E. P. F. A. a. F., Younes, M., Aquilina, G., Castle, L., Fowler, P., Frutos Fernandez, M. J., Fürst, P., Gundert-Remy, U., Gürtler, R., Husøy, T., Manco, M., Mennes, W., Moldeus, P., Passamonti, S., Shah, R., Waalkens-Berendsen, I., Wölfle, D., Wright, M., Benigni, R., Bolognesi, C., Boon, P., Chipman, K., De Knecht, J., Sahlin, U., Arcella, D., Barmaz, S., Carfì, M., Martino, C., Tard, A., Vianello, G., Engel, K.

    EFSA Journal, vol. 19

    Contributions to Specialist Publications: Articles

  • Scientific Opinion on Flavouring Group Evaluation 13 Revision 3 (FGE.13Rev3): furfuryl and furan derivatives with and without additional side-chain substituents and heteroatoms from chemical group 14

    Additives, E. P. F., (FAF), F., Younes, M., Aquilina, G., Castle, L., Engel, K., Fowler, P., Frutos Fernandez, M. J., Fürst, P., Gundert-Remy, U., Gürtler, R., Husøy, T., Manco, M., Moldeus, P., Passamonti, S., Shah, R., Waalkens-Berendsen, I., Wölfle, D., Wright, M., Benigni, R., Bolognesi, C., Chipman, K., Cordelli, E., Degen, G., Marzin, D., Svendsen, C., Carfì, M., Vianello, G., Mennes, W.

    EFSA Journal, vol. 19, pp. e06386

    Contributions to Specialist Publications: Articles

  • Scientific Opinion on Flavouring Group Evaluation 67, Revision 3 (FGE.67Rev3): consideration of 23 furan-substituted compounds evaluated by JECFA at the 55th, 65th, 69th and 86th meetings

    Additives, E. P. F., (FAF), F., Younes, M., Aquilina, G., Castle, L., Engel, K., Fowler, P., Frutos Fernandez, M. J., Fürst, P., Gundert-Remy, U., Gürtler, R., Husøy, T., Manco, M., Moldeus, P., Passamonti, S., Shah, R., Waalkens-Berendsen, I., Wölfle, D., Wright, M., Benigni, R., Bolognesi, C., Chipman, K., Cordelli, E., Degen, G., Marzin, D., Svendsen, C., Carfì, M., Vianello, G., Mennes, W.

    EFSA Journal, vol. 19, pp. e06362

    Contributions to Specialist Publications: Articles

  • Over-the-counter analgesics during pregnancy: a comprehensive review of global prevalence and offspring safety

    Zafeiri, A., Mitchell, R. T., Hay, D. C., Fowler, P. A.

    Human Reproduction Update, vol. 27, no. 1, pp. 67–95

    Contributions to Journals: Articles

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