Professor Gernot Riedel

Systematic gait analysis in alpha-synuclein transgenic line 62 mice using the CatWalk

2026 - Published

Schwab, K., Robinson, L., Bray, J., Anschuetz, A., Mondesir, M., Magri', M., Harrington, C., Riedel, G.

Behavioural Brain Research, vol. 496, 115819

Contributions to Journals: Articles

[ONLINE] DOI: https://doi.org/10.1016/j.bbr.2025.115819
[OPEN ACCESS] http://aura.abdn.ac.uk/bitstreams/7c7b8eee-d670-4e6e-9d18-97a78483d184/download

Proteomic and non-proteomic changes of presynaptic proteins in animal models of Alzheimer’s disease: A meta-analysis 2015-2023

2025 - Published

Anschuetz, A., Schwab, K., Harrington, C., Wischik, C., Riedel, G.

Journal of Alzheimer's Disease, vol. 107, no. 2, pp. 452-476

Contributions to Journals: Articles

[ONLINE] DOI: https://doi.org/10.1177/13872877251362212
[OPEN ACCESS] http://aura.abdn.ac.uk/bitstreams/7a9cc0f7-7c67-4f4a-a8e5-c989c8f36970/download

In memory of Dr Emily Jutkiewicz, 1975-2024

2025 - Published

Ellenbroek, B. A., Vanderschuren, L. J., Riedel, G.

Behavioural pharmacology, vol. 36, no. 4, pp. 161-162

Contributions to Journals: Articles

[ONLINE] DOI: https://doi.org/10.1097/FBP.0000000000000829
[ONLINE] View publication in Scopus

Hydromethylthionine sustains truncated tau-dependent inflammation-lowering effects in mouse brain

2025 - Published

Coelho Dos Santos, R., Lee, S. H., Lofthouse, R. A., Melis, V., Strachan, L., Leith, M., Dreesen, E., Armstrong, P., Vorley, T., Goatman, E., Hull, C., Riedel, G., Wischik, C., Harrington, C.

FEBS Journal, vol. 292, no. 10, pp. 2602-2623

Contributions to Journals: Articles

[ONLINE] DOI: https://doi.org/10.1111/febs.70021
[OPEN ACCESS] http://aura.abdn.ac.uk/bitstreams/372a1f89-dc2a-4be5-a64e-19083dc6d8d6/download
[ONLINE] View publication in Scopus

Effects of age and dietary methionine restriction on cognitive and behavioural phenotypes in the rTg4510 mouse model of frontotemporal dementia

2025 - Published

Souza Matos, M., Sil, A., Riedel, G., Platt, B., Delibegovic, M.

Neurobiology of Aging, vol. 146, pp. 24-37

Contributions to Journals: Articles

[ONLINE] DOI: https://doi.org/10.1016/j.neurobiolaging.2024.11.004
[OPEN ACCESS] http://aura.abdn.ac.uk/bitstreams/48bd9d68-9ae6-4d38-8998-97a78648f0ac/download

PLB2Tau mice are impaired in novel and temporal object recognition and show corresponding traits in brain MRI

2025 - Published

Micheau, J., Catheline, G., Barse, E., Hiba, B., Marcilhac, A., Allard, M., Platt, B., Riedel, G.

Brain Research Bulletin, vol. 220, 111161

Contributions to Journals: Articles

[ONLINE] DOI: https://doi.org/10.1016/j.brainresbull.2024.111161
[OPEN ACCESS] http://aura.abdn.ac.uk/bitstreams/317c532a-6361-4c05-b4dd-45ebbaf2293a/download

Rivastigmine interferes with the pharmacological activity of hydromethylthionine on presynaptic proteins in the line 66 model of frontotemporal dementia

2025 - Published

Schwab, K., Strachan, L., Anschuetz, A., Dreesen, E. S., Magbagbeolu, M., Melis, V., Theuring, F., Harrington, C., Wischik, C., Riedel, G.

Brain Research Bulletin, vol. 220, 111172

Contributions to Journals: Articles

[ONLINE] DOI: https://doi.org/10.1016/j.brainresbull.2024.111172
[OPEN ACCESS] http://aura.abdn.ac.uk/bitstreams/50808b59-567a-4211-a048-cd17a2095954/download

High-affinity antibodies specific to the core region of the tau protein exhibit diagnostic and therapeutic potential for Alzheimer’s disease

2024 - Published

Arastoo, M., Penny, L. K., Lofthouse, R. A., Abdallah, A., Abrahamsson, A., Marini, P., Melis, V., Riedel, G., Harrington, C., Wischik, C., Porter, A., Palliyil, S.

Alzheimer's Research & Therapy, vol. 16, 209

Contributions to Journals: Articles

[ONLINE] DOI: https://doi.org/10.1186/s13195-024-01561-1
[OPEN ACCESS] http://aura.abdn.ac.uk/bitstreams/16d6fd7f-e75d-41e6-9988-873e405154e6/download
[ONLINE] View publication in Scopus

Evaluation of variation in preclinical electroencephalographic (EEG) spectral power across multiple laboratories and experiments: An EQIPD study

2024 - Published

Ahuis, T. P., Smyk, M. K., Laloux, C., Aulehner, K., Bray, J., Waldron, A., Miljanovic, N., Seiffert, I., Song, D., Boulanger, B., Jucker, M., Potschka, H., Platt, B., Riedel, G., Voehringer, P., Nicholson, J. R., Drinkenburg, W. H. I. M., Kas, M. J. H., Leiser, S. C.

PloS ONE, vol. 19, no. 10, e0309521

Contributions to Journals: Articles

[ONLINE] DOI: https://doi.org/10.1371/journal.pone.0309521
[OPEN ACCESS] http://aura.abdn.ac.uk/bitstreams/c454e2e1-f991-49c7-ab2d-c7e752a94877/download

Rescue of synaptosomal glutamate release defects in tau transgenic mice by the tau aggregation inhibitor hydromethylthionine

2024 - Published

Cranston, A., Kraev, I., Stewart, M. G., Horsley, D., Robinson, L., Dreesen, E. S., Armstrong, P., Palliyil, S., Harrington, C., Wischik, C., Riedel, G.

Cellular Signalling, vol. 121, 111269

Contributions to Journals: Articles

[ONLINE] DOI: https://doi.org/10.1016/j.cellsig.2024.111269
[OPEN ACCESS] http://aura.abdn.ac.uk/bitstreams/d54bb6ea-885a-4e6b-8bcd-28e50ba2fe67/download

Mouse Exploratory Behaviour in the Open Field with and without NAT-1 EEG Device: Effects of MK801 and Scopolamine

2024 - Published

Lim, C. J., Bray, J., Janhunen, S. K., Platt, B., Riedel, G.

Biomolecules, vol. 14, no. 8, 1008

Contributions to Journals: Articles

[ONLINE] DOI: https://doi.org/10.3390/biom14081008
[OPEN ACCESS] http://aura.abdn.ac.uk/bitstreams/8db1b223-7750-4ceb-9ec4-cbe2a706770b/download
[ONLINE] View publication in Scopus

Hydromethylthionine rescues synaptic SNARE proteins in a mouse model of tauopathies: interference by cholinesterase inhibitors

2024 - Published

Schwab, K., Lauer, D., Magbagbeolu, M., Institute, M., Institute, M., Institute, M., Harrington, C. R., Wischik, C. M., Niewiadomska, G., Riedel, G.

Brain Research Bulletin, vol. 212, 110955

Contributions to Journals: Articles

[ONLINE] https://www.sciencedirect.com/science/article/pii/S0361923024000881
[ONLINE] DOI: https://doi.org/10.1016/j.brainresbull.2024.110955
[OPEN ACCESS] http://aura.abdn.ac.uk/bitstreams/911fd769-9219-463f-83d9-b5ff9071cb3d/download

LETC inhibits α-Syn aggregation and ameliorates motor deficiencies in the L62 mouse model of synucleinopathy

2024 - Published

Schwab, K., Frahm, S., Magbagbeolu, M., Horsley, D., Goatman, E., Melis, V., Theuring, F., Ishaq, A., Storey, J. M. D., Harrington, C., Wischik, C., Riedel, G.

European Journal of Pharmacology, vol. 970, 176505

Contributions to Journals: Articles

[ONLINE] DOI: https://doi.org/10.1016/j.ejphar.2024.176505
[OPEN ACCESS] http://aura.abdn.ac.uk/bitstreams/9d89be2d-c6b8-49cc-bb79-e013038af2ec/download

Neuroprotection of Cholinergic Neurons with a Tau Aggregation Inhibitor and Rivastigmine in an Alzheimer's-like Tauopathy Mouse Model

2024 - Published

Zadrozny, M., Drapich, P., Gasiorowska-Bien, A., Niewiadomski, W., Harrington, C. R., Wischik, C. M., Riedel, G., Niewiadomska, G.

Cells, vol. 13, no. 7, 642

Contributions to Journals: Articles

[ONLINE] DOI: https://doi.org/10.3390/cells13070642
[OPEN ACCESS] http://aura.abdn.ac.uk/bitstreams/ca875772-85c5-4a84-8836-b35df823e61b/download

Solubility of α-synuclein species in the L62 mouse model of synucleinopathy

2024 - Published

Schwab, K., Magbagbeolu, M., Theuring, F., Harrington, C., Wischik, C., Riedel, G.

Scientific Reports, vol. 14, 6239

Contributions to Journals: Articles

[ONLINE] DOI: https://doi.org/10.1038/s41598-024-56735-6
[OPEN ACCESS] http://aura.abdn.ac.uk/bitstreams/798dca69-b204-4811-bd11-ff81161eebce/download

Reproducibility in Preclinical in Vivo Research: Statistical Inferences

2024 - Published

Lim, C. J., Janhunen, S. K., Riedel, G.

Journal of Integrative Neuroscience, vol. 23, no. 2, jin2302030

Contributions to Journals: Editorials

[ONLINE] DOI: https://doi.org/10.31083/j.jin2302030
[OPEN ACCESS] http://aura.abdn.ac.uk/bitstreams/1045c7ce-d99e-4642-9c38-c0e5531d48b6/download
[ONLINE] View publication in Scopus

Apathy-like behaviour in tau mouse models of Alzheimer’s disease and frontotemporal dementia

2024 - Published

Robinson, L., Dreesen, E., Mondesir, M., Harrington, C., Wischik, C., Riedel, G.

Behavioural Brain Research, vol. 456, 114707

Contributions to Journals: Articles

[ONLINE] https://www.sciencedirect.com/science/article/pii/S0166432823004254
[ONLINE] DOI: https://doi.org/10.1016/j.bbr.2023.114707
[OPEN ACCESS] http://aura.abdn.ac.uk/bitstreams/aea69e4a-9c79-4f34-a4e5-b40c41c74126/download

A Meta-Analysis on Presynaptic Changes in Alzheimer's Disease

2024 - Published

Anschuetz, A., Schwab, K., Harrington, C. R., Wischik, C. M., Riedel, G.

Journal of Alzheimer's Disease, vol. 97, no. 1, pp. 145-162

Contributions to Journals: Articles

[ONLINE] DOI: https://doi.org/10.3233/JAD-231034
[OPEN ACCESS] http://aura.abdn.ac.uk/bitstreams/3addf8f1-3f99-45b5-b850-d0bad61a2a40/download

Genetic basis of anatomical asymmetry and aberrant dynamic functional networks in Alzheimer’s disease

2023 - Published

Rubido, N., Riedel, G., Vuksanović, V.

Brain Communications, vol. 6, no. 1, fcad320

Contributions to Journals: Articles

[ONLINE] DOI: https://doi.org/10.1093/braincomms/fcad320
[OPEN ACCESS] http://aura.abdn.ac.uk/bitstreams/7b46f8fe-806d-41a9-bcd6-61e5a1ce56a4/download

Comparison of automated video tracking systems in the open field test: ANY-Maze versus EthoVision XT

2023 - Published

Lim, C. J. M., Platt, B., Janhunen, S. K., Riedel, G.

Journal of Neuroscience Methods, vol. 397, 109940

Contributions to Journals: Articles

[ONLINE] DOI: https://doi.org/10.1016/j.jneumeth.2023.109940
[OPEN ACCESS] http://aura.abdn.ac.uk/bitstreams/4082964e-bb0d-4a69-8ba2-3c5dc897b922/download
[ONLINE] View publication in Scopus

Mitochondrial Effects of Hydromethylthionine, Rivastigmine and Memantine in Tau-Transgenic Mice

2023 - Published

Kondak, C., Leith, M., Baddeley, T. C., Santos, R. X., Harrington, C. R., Wischik, C. M., Riedel, G., Klein, J.

International Journal of Molecular Sciences, vol. 24, no. 13, 10810

Contributions to Journals: Articles

[ONLINE] DOI: https://doi.org/10.3390/ijms241310810
[OPEN ACCESS] http://aura.abdn.ac.uk/bitstreams/f25eee8a-d88e-4932-8d2f-6574bcb547cf/download

Neurochemical, histological and behavioral profiling of the acute, sub-acute and chronic MPTP mouse model of Parkinson’s disease

2023 - Published

Santoro, M., Fadda, P., Clephan, K. J., Hull, C., Teismann, P., Platt, B., Riedel, G.

Journal of Neurochemistry, vol. 164, no. 2, pp. 121-142

Contributions to Journals: Articles

[ONLINE] DOI: https://doi.org/10.1111/jnc.15699
[OPEN ACCESS] http://aura.abdn.ac.uk/bitstreams/fd9b9045-05bf-47b6-9d5b-f3e2d404354a/download

The EQIPD framework for rigor in the design, conduct, analysis and documentation of animal experiments

2022 - Published

Vollert, J., Macleod, M., Dirnagl, U., Kas, M. J., Michel, M. C., Potschka, H., Riedel, G., Wever, K. E., Würbel, H., Steckler, T., Rice, A. S., EQIPD Consortium

Nature methods, vol. 19, pp. 1334–1337

Contributions to Journals: Comments and Debates

[ONLINE] DOI: https://doi.org/10.1038/s41592-022-01615-y
[ONLINE] View publication in Scopus

Glutamatergic transmission and receptor expression in the synucleinopathy h-α-synL62 mouse model: Effects of hydromethylthionine

2022 - Published

Schwab, K., Chasapopoulou, Z., Frahm, S., Magbagbeolu, M., Cranston, A., Harrington, C. R., Wischik, C. M., Theuring, F., Riedel, G.

Cellular Signalling, vol. 97, 110386

Contributions to Journals: Articles

[ONLINE] https://www.sciencedirect.com/science/article/pii/S0898656822001486
[ONLINE] DOI: https://doi.org/10.1016/j.cellsig.2022.110386
[OPEN ACCESS] http://aura.abdn.ac.uk/bitstreams/ea4865a6-a9d9-45aa-9ac8-d93d5b4f39d9/download

HMTM-Mediated Enhancement of Brain Bioenergetics in a Mouse Tauopathy Model Is Blocked by Chronic Administration of Rivastigmine

2022 - Published

Santos, R. X., Melis, V., Goatman, E. A., Leith, M., Baddeley, T. C., Storey, J. M., Riedel, G., Wischik, C. M., Harrington, C. R.

Biomedicines, vol. 10, no. 4, 867

Contributions to Journals: Articles

[ONLINE] DOI: https://doi.org/10.3390/biomedicines10040867
[OPEN ACCESS] http://aura.abdn.ac.uk/bitstreams/161666d1-4323-45bc-9b3c-26c075dc2edd/download
[ONLINE] View publication in Scopus

Systematic gait analysis in alpha-synuclein transgenic line 62 mice using the CatWalk

Proteomic and non-proteomic changes of presynaptic proteins in animal models of Alzheimer’s disease: A meta-analysis 2015-2023

In memory of Dr Emily Jutkiewicz, 1975-2024

Hydromethylthionine sustains truncated tau-dependent inflammation-lowering effects in mouse brain

Effects of age and dietary methionine restriction on cognitive and behavioural phenotypes in the rTg4510 mouse model of frontotemporal dementia

PLB2Tau mice are impaired in novel and temporal object recognition and show corresponding traits in brain MRI

Rivastigmine interferes with the pharmacological activity of hydromethylthionine on presynaptic proteins in the line 66 model of frontotemporal dementia

High-affinity antibodies specific to the core region of the tau protein exhibit diagnostic and therapeutic potential for Alzheimer’s disease

Evaluation of variation in preclinical electroencephalographic (EEG) spectral power across multiple laboratories and experiments: An EQIPD study

Rescue of synaptosomal glutamate release defects in tau transgenic mice by the tau aggregation inhibitor hydromethylthionine

Mouse Exploratory Behaviour in the Open Field with and without NAT-1 EEG Device: Effects of MK801 and Scopolamine

Hydromethylthionine rescues synaptic SNARE proteins in a mouse model of tauopathies: interference by cholinesterase inhibitors

LETC inhibits α-Syn aggregation and ameliorates motor deficiencies in the L62 mouse model of synucleinopathy

Neuroprotection of Cholinergic Neurons with a Tau Aggregation Inhibitor and Rivastigmine in an Alzheimer's-like Tauopathy Mouse Model

Solubility of α-synuclein species in the L62 mouse model of synucleinopathy

Reproducibility in Preclinical in Vivo Research: Statistical Inferences

Apathy-like behaviour in tau mouse models of Alzheimer’s disease and frontotemporal dementia

A Meta-Analysis on Presynaptic Changes in Alzheimer's Disease

Genetic basis of anatomical asymmetry and aberrant dynamic functional networks in Alzheimer’s disease

Comparison of automated video tracking systems in the open field test: ANY-Maze versus EthoVision XT

Mitochondrial Effects of Hydromethylthionine, Rivastigmine and Memantine in Tau-Transgenic Mice

Neurochemical, histological and behavioral profiling of the acute, sub-acute and chronic MPTP mouse model of Parkinson’s disease

The EQIPD framework for rigor in the design, conduct, analysis and documentation of animal experiments

Glutamatergic transmission and receptor expression in the synucleinopathy h-α-synL62 mouse model: Effects of hydromethylthionine

HMTM-Mediated Enhancement of Brain Bioenergetics in a Mouse Tauopathy Model Is Blocked by Chronic Administration of Rivastigmine

Refine

Books and Reports

Chapters in Books, Reports and Conference Proceedings

Contributions to Conferences

Contributions to Journals

Patents