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Health Economics Research Unit (HERU)

Professor Alison Avenell

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Professor Alison Avenell
Professor Alison Avenell
Professor Alison Avenell

Clinical Chair in Health Services Research

About
Email Address
a.avenell@abdn.ac.uk
Telephone Number
+44 (0)1224 438164
Office Address

Health Services Research Unit
3rd Floor Health Sciences Building
Foresterhill
Aberdeen
AB25 2ZD

School/Department
School of Medicine, Medical Sciences and Nutrition

Biography

Alison Avenell joined the Unit in 1998, as a Clinical Research Fellow. She was subsequently funded by the Chief Scientist Office (CSO) of the Scottish Government Health Directorates as a Clinical Research Fellow to undertake research in the MRC funded RECORD trial, which examined the effect of calcium and/or vitamin D supplementation in the secondary prevention of osteoporotic fractures. She also led the MAVIS trial which examined the effectiveness of vitamin and mineral supplementation in preventing infections in older people, and helped lead the SIGNET trial of glutamine and selenium supplementation in critical illness. She was a CSO funded Career Scientist and currently has a clinical chair in health services research and is an Honorary Consultant in Clinical Biochemistry, undertaking systematic reviews and randomised controlled trials of treatments for adult obesity, and under-nutrition in clinical practice.

Research

Current Research

Current projects

Completed projects

Publications

Page 1 of 5 Results 1 to 50 of 234

  • Inconsistency in publishers’ responses to integrity concerns about published research: Evidence and suggested improvements

    Grey, A., Avenell, A., Gaby, A., Bolland, M. J.
    Journal of Clinical Epidemiology, vol. 186, 111918
    Contributions to Journals: Articles

  • Dismantling Behavioural Weight Management Interventions: Component Network Meta-analysis of Randomised Controlled trials and Real-World Services

    Jaiswal, N., Gregg, R., Hawkins, N., Sharif, S., Avenell, A., Ells, L., Jayacodi, S., Mackenzie, R., Simpson, S. A., Wu, O., Logue, J.
    Health Technology Assessment
    Contributions to Journals: Articles

  • Assessing the feasibility and impact of clinical trial trustworthiness checks via an application to Cochrane Reviews: Stage 2 of the INSPECT-SR project

    Wilkinson, J., Heal, C., Antoniou, G. A., Flemyng, E., Ahnström, L., Alteri, A., Avenell, A., Barker, T. H., Borg, D. N., Brown, N. J. L., Buhmann, R., Calvache, J. A., Carlsson, R., Carter, L., Cashin, A. G., Cotterill, S., Färnqvist, K., Ferraro, M. C., Grohmann, S., Gurrin, L. C., Hayden, J. A., Hunter, K. E., Hyltse, N., Jung, L., Krishan, A., Laporte, S., Lasserson, T. J., Laursen, D. R. T., Lensen, S., Li, W., Li, T., Liu, J., Locher, C., Lu, Z., Lundh, A., Marsden, A., Meyerowitz-Katz, G., Mol, B. W., Munn, Z., Naudet, F., Nunan, D., O'Connell, N. E., Olsson, N., Parker, L., Patetsini, E., Redman, B., Rhodes, S., Richardson, R., Ringsten, M., Rogozińska, E., Seidler, A. L., Sheldrick, K., Stocking, K., Sydenham, E., Thomas, H., Tsokani, S., Vinatier, C., Vorland, C. J., Wang, R., Al Wattar, B. H., Weber, F., Weibel, S., van Wely, M., Xu, C., Bero, L., Kirkham, J. J.
    Journal of Clinical Epidemiology, vol. 184, 111824
    Contributions to Journals: Articles

  • Secondary analysis of the Game of Stones trial for men with obesity: Examining moderator effects and exploratory outcomes

    Dombrowski, S. U., Hoddinott, P., Macaulay, L., O’Dolan, C., Swingler, J., Cotton, S., Avenell, A., Getaneh, A., Gray, C., Hunt, K., Kee, F., MacLean, A., McKinley, M. C., Torrens, C., Turner, K., Van der Pol, M., MacLennan, G.
    Obesity, vol. 33, no. 8, pp. 1432-1446
    Contributions to Journals: Articles

  • Problematic studies have huge impact on healthcare evidence

    Studd, H., Avenell, A., Bolland, M. J., Grey, A.
    BMJ (Clinical research ed.), vol. 390, pp. r1412
    Contributions to Journals: Letters

  • Biochemical osteomalacia in adults undergoing vitamin D testing in the North-East of Scotland

    MacLeod, A., Bolland, M. J., Balfour, A., Grey, A., Newmark, J., Avenell, A.
    Annals of Clinical Biochemistry, vol. 62, no. 4, pp. 303-311
    Contributions to Journals: Articles

  • Text messaging with or without financial incentives versus a waitlist control for weight loss in men: cost-effectiveness analysis of the Game of Stones randomised controlled trial

    Getaneh, A., van der Pol, M., Boyers, D., Avenell, A., Cotton, S., Dombrowski, S. U., Gray, C., Kee, F., Macaulay, L., McKinley, M. C., O'Dolan, C., Swingler, J., Torrens, C., Turner, K., MacLennan, G., Hoddinott, P.
    The Lancet Regional Health - Europe, vol. 54, 101328
    Contributions to Journals: Articles

  • The effect of dietary weight-loss interventions on the inflammatory markers Interleukin-6 and TNF-alpha in adults with obesity: A systematic review and meta-analysis of randomised controlled clinical trials

    Bulmer, C., Avenell, A.
    Obesity Reviews, vol. 26, no. 7, e13910
    Contributions to Journals: Articles

  • Investigating Health Professionals’ Perspectives and Experiences of Food Security-Related Conversations in Diabetes Care

    Mohamed, S., Avenell, A., Douglas, F., Keen, A.
    Diabetic Medicine, vol. 42, no. 3, e15470
    Contributions to Journals: Articles

  • The Fetal Pillow Deflates—Lessons for All

    Grey, A., Avenell, A., Bolland, M. J., Thornton, J. G.
    BJOG: An International Journal of Obstetrics and Gynaecology, vol. 132, no. 4, pp. 429-432
    Contributions to Journals: Comments and Debates

  • Accuracy and distribution of baseline categorical variables and p-values in spine randomized controlled trials

    Bolland, M. J., Avenell, A., Grey, A.
    Royal Society Open Science, vol. 12, no. 1, 240170
    Contributions to Journals: Articles

  • Laparoscopic cholecystectomy versus conservative management for uncomplicated symptomatic gallstones: economic evaluation based on the C-GALL trial

    Hernández, R. A., Ahmed, I., Edwards, K., Hudson, J., Gillies, K., Bruce, R., Bell, V., Avenell, A., Blazeby, J. M., Brazzelli, M., Cotton, S., Croal, B. L., MacLennan, G., Murchie, P., Ramsay, C.
    British Journal of Surgery, vol. 112, no. 1, znae293
    Contributions to Journals: Articles

  • Publication integrity: what is it, why does it matter, how it is safeguarded and how could we do better?

    Bolland, M. J., Avenell, A., Grey, A.
    Journal of the Royal Society of New Zealand, vol. 55, no. 2, pp. 267-286
    Contributions to Journals: Review articles

  • Ten years later: assessments of the integrity of publications from one research group with multiple retractions

    Grey, A., Avenell, A., Bolland, M. J.
    Accountability in Research, vol. 32, no. 4, pp. 488-508
    Contributions to Journals: Articles

  • A survey of experts to identify methods to detect problematic studies: Stage 1 of the INSPECT-SR Project

    Wilkinson, J., Heal, C., Antoniou, G. A., Flemyng, E., Avenell, A., Barbour, V., Bordewijk, E., Brown, N. J. L., Clarke, M., Dumville, J. C., Grohmann, S., Gurrin, L. C., Hayden, J. A., Hunter, K. E., Lam, E., Lasserson, T., Li, T., Lensen, S. F., Liu, J., Lundh, A., Meyerowitz-Katz, G., Mol, B. W., O’Connell, N. E., Parker, L., Redman, B., Seidler, A. L., Sheldrick, K. A., Sydenham, E., Dahly, D. L., van Wely, M., Bero, L., Kirkham, J.
    Journal of Clinical Epidemiology, vol. 175, 111512
    Contributions to Journals: Articles

  • Barriers to investigating and reporting research misconduct: prioritising publication integrity

    Avenell, A., Klein, A. A., Byrne, J. A., Wilmshurst, P., Bolland, M. J., Grey, A.
    BMJ (Clinical research ed.), vol. 386, q2018
    Contributions to Journals: Articles

  • Association of bradykinin receptor 2 (BDKRB2) variants with physical performance and muscle mass: findings from the LACE sarcopenia trial

    Shrestha, A., Bashir, T., Achison, M., Adamson, S., Akpan, A., Aspray, T. J., Avenell, A., Band, M. M., Burton, L. A., Cvoro, V., Donnan, P. T., Duncan, G. W., George, J., Gordon, A. L., Gregson, C. L., Hapca, A., Hume, C. L., Jackson, T. A., Kerr, S., Kilgour, A. H. M., Masud, T., McKenzie, A., McKenzie, E., Patel, H., Pilvinyte, K., Roberts, H. C., Sayer, A. A., Rossios, C., Smith, K. T., Soiza, R., Steves, C. J., Struthers, A. D., Tiwar, D., Whitney, J., Witham, M. D., Kemp, P. R.
    PloS ONE, vol. 19, no. 8, e0307268
    Contributions to Journals: Articles

  • How to improve assessments of publication integrity

    Grey, A., Avenell, A., Klein, A. A., Byrne, J. A., Wilmshurst, P., Bolland, M. J.
    Nature, vol. 632, no. 8023, pp. 26-28
    Contributions to Journals: Comments and Debates

  • Text Messages With Financial Incentives for Men With Obesity: A Randomized Clinical Trial

    Hoddinott, P., O'Dolan, C., Macaulay, L., Dombrowski, S. U., Swingler, J., Cotton, S., Avenell, A., Getaneh, A. M., Gray, C., Hunt, K., Kee, F., MacLean, A., McKinley, M., Torrens, C., Turner, K., van der Pol, M., MacLennan, G.
    JAMA, vol. 332, no. 1, pp. 31-40
    Contributions to Journals: Articles

  • Laparoscopic cholecystectomy versus conservative management for adults with uncomplicated symptomatic gallstones: the C-GALL RCT

    Innes, K., Ahmed, I., Hudson, J., Hernández, R. A., Gillies, K., Bruce, R., Bell, V., Avenell, A., Blazeby, J. M., Brazzelli, M., Cotton, S., Croal, B., Forrest, M., MacLennan, G., Murchie, P., Wileman, S., Ramsay, C.
    Health Technology Assessment, vol. 28, no. 26, pp. 1-151
    Contributions to Journals: Articles

  • Statistical Techniques to Assess Publication Integrity in Groups of Randomised Trials: A Narrative Review

    Bolland, M. J., Avenell, A., Grey, A.
    Journal of Clinical Epidemiology, vol. 170, 111365
    Contributions to Journals: Articles

  • Guidance on terminology, application, and reporting of citation searching: the TARCiS statement

    Hirt, J., Nordhausen, T., Fuerst, T., Ewald, H., Appenzeller-Herzog, C., TARCiS study group, Avenell, A.
    BMJ, vol. 385, e078384
    Contributions to Journals: Articles

  • Letter to the editor concerning "characteristics of baseline frequency data in spinal RCTs do not suggest widespread non-random allocation" by MMS Levayer, et al. (Eur Spine J; 2023; 32: 3009-3014)

    Bolland, M. J., Avenell, A., Grey, A.
    European Spine Journal, vol. 33, no. 4, pp. 1703-1704
    Contributions to Journals: Letters

  • A survey of experts to identify methods to detect problematic studies: Stage 1 of the INSPECT-SR Project

    Wilkinson, J., Heal, C., Antoniou, G. A., Flemyng, E., Avenell, A., Barbour, V., Bordewijk, E. M., Brown, N. J. L., Clarke, M., Dumville, J., Grohmann, S., Gurrin, L. C., Hayden, J. A., Hunter, K. E., Lam, E., Lasserson, T., Li, T., Lensen, S., Liu, J., Lundh, A., Meyerowitz-Katz, G., Mol, B. W., O'Connell, N. E., Parker, L., Redman, B., Seidler, A. L., Sheldrick, K., Sydenham, E., Dahly, D. L., van Wely, M., Bero, L., Kirkham, J. J.
    Working Papers: Preprint Papers

  • Protocol for the development of a tool (INSPECT-SR) to identify problematic randomised controlled trials in systematic reviews of health interventions

    Wilkinson, J., Heal, C., Antoniou, G. A., Flemyng, E., Alfirevic, Z., Avenell, A., Barbour, V., Brown, N. J. L., Carlisle, J., Clarke, M., Dicker, P., Dumville, J., Grey, A., Grohmann, S., Gurrin, L. C., Hayden, J. A., Heathers, J., Hunter, K. E., Lasserson, T., Lam, E., Lensen, S., Li, T., Li, W., Loder, E., Lundh, A., Meyerowitz-Katz, G., Mol, B. W., O’Connell, N. E., Parker, L., Redman, B. K., Seidler, A. L., Sheldrick, K. A., Sydenham, E., Torgerson, D. J., Wely, M. v., Wang, R., Bero, L., Kirkham, J. J.
    BMJ Open, vol. 14, no. 3, e084164
    Contributions to Journals: Articles

  • A randomized trial alerting authors, with or without co-authors or editors, that research they cited in systematic reviews and guidelines has been retracted

    Avenell, A., Bolland, M. J., Gamble, G. D., Grey, A.
    Accountability in Research, vol. 31, no. 1, pp. 14-37
    Contributions to Journals: Articles

  • Designing financial incentives for health behaviour change: a mixed-methods case study of weight loss in men with obesity

    van der Pol, M., Mcdonald, M., Collacott, H. E., Dombrowski, S., Harris, F., Kee, F., Avenell, A., Gray, C., Skinner, R., Hoddinott, P.
    Journal of Public Health, vol. 32, no. 1, pp. 65-77
    Contributions to Journals: Articles

  • Effectiveness of conservative management versus laparoscopic cholecystectomy in the prevention of recurrent symptoms and complications in adults with uncomplicated symptomatic gallstone disease (C-GALL trial): pragmatic, multicentre randomised controlled trial

    Ahmed, I., Hudson, J., Innes, K., Hernández, R., Gillies, K., Bruce, R., Bell, V., Avenell, A., Blazeby, J., Brazzelli, M., Cotton, S., Croal, B., Forrest, M., MacLennan, G., Murchie, P., Wileman, S., Ramsay, C.
    BMJ, vol. 383, e075383
    Contributions to Journals: Articles

  • Letter to the editor: Validity of tests for publication integrity

    Bolland, M. J., Avenell, A., Grey, A.
    International Journal of Gynecology & Obstetrics, vol. 163, no. 3, pp. 1043-1044
    Contributions to Journals: Letters

  • Activin type I receptor polymorphisms and body composition in older individuals with sarcopenia – analyses from the LACE randomised controlled trial

    Bashir, T., Achison, M., Adamson, S., Akpan, A., Aspray, T. J., Avenell, A., Burton, L. A., Cvoro, V., Donnan, P. T., Duncan, G. W., George, J., Gordon, A. L., Gregson, C. L., Hapca, A., Hume, C. L., Jackson, T., Kerr, S., Kilgour, A. H. M., Masud, T., McKenzie, A., McKenzie, E., Patel, H., Pilvinyte, K., Roberts, H. C., Rossios, C., Sayer, A. A., Smith, K. T., Soiza, R., Steves, C. J., Struthers, A. D., Tiwari, D., Whitney, J., Witham, M. D., Kemp, P. R.
    PloS ONE, vol. 18, no. 11 November, e0294330
    Contributions to Journals: Articles

  • ACE I/D genotype associates with strength in sarcopenic men but not with response to ACE inhibitor therapy in older adults with sarcopenia: Results from the LACE trial

    Rossios, C., Bashir, T., Adamson, S., Adamson, S., Akpan, A., Aspray, T. J., Avenell, A., Band, M. M., Burton, L. A., Cvoro, V., Donnan, P. T., Duncan, G. W., George, J., Gordon, A. L., Gregson, C. L., Hapca, A., Hume, C. L., Jackson, T. A., Kerr, S., Kilgour, A. H. M., Masud, T., McKenzie, A., McKenzie, E., Patel, H., Pilvinyte, K., Roberts, H. C., Sayer, A. A., Smith, K. T., Soiza, R., Steves, C. J., Struthers, A. D., Tiwari, D., Whitney, J., Witham, M. D., Kemp, P. R.
    PloS ONE, vol. 18, no. 10, e0292402
    Contributions to Journals: Articles

  • Protocol for the development of a tool (INSPECT-SR) to identify problematic randomised controlled trials in systematic reviews of health interventions

    Wilkinson, J., Heal, C., Antoniou, G. A., Flemyng, E., Alfirevic, Z., Avenell, A., Barbour, V., Brown, N. J. L., Carlisle, J., Clarke, M., Dicker, P., Dumville, J., Grey, A., Gurrin, L. C., Hayden, J. A., Heathers, J., Hunter, K. E., Lasserson, T., Lensen, S., Li, T., Li, W., Loder, E., Lundh, A., Meyerowitz-Katz, G., Mol, B. W., O' Connell, N. E., Parker, L., Redman, B. K., Seidler, A. L., Sheldrick, K. A., Sydenham, E., Torgerson, D. J., van Wely, M., Wang, R., Bero, L., Kirkham, J. J., Lam, E.
    Working Papers: Preprint Papers

  • Responses to concerns raised about publications don’t address the concerns raised

    Bolland, M. J., Avenell, A., Grey, A.
    British Journal of Pain, vol. 17, no. 5, pp. 426-427
    Contributions to Journals: Articles

  • The effect of weight loss interventions for obesity on fertility and pregnancy outcomes: a systematic review and meta-analysis

    Boyle, B. R., Ablett, A. D., Ochi, C., Hudson, J., Watson, L., Rauh, D., Avenell, A.
    International Journal of Gynecology and Obstetrics, vol. 161, no. 2, pp. 335-342
    Contributions to Journals: Articles

  • Analysis of cluster randomised trials as if they were individually randomised

    Bolland, M. J., Avenell, A., Grey, A.
    The lancet. Diabetes & endocrinology, vol. 11, no. 2, pp. 75
    Contributions to Journals: Comments and Debates

  • Distributions of baseline categorical variables were different from the expected distributions in randomized trials with integrity concerns

    Bolland, M. J., Gamble, G. D., Avenell, A., Cooper, D. J., Grey, A.
    Journal of Clinical Epidemiology, vol. 154, pp. 117-124
    Contributions to Journals: Articles

  • A Systematic Review of the evidence for Non-surgical weight management for adults with severe obesity: What is cost effective and what are the implications for the Design of health Services?

    Jacobsen, E., Boyers, D., Manson, P., Avenell, A.
    Current Obesity Reports, vol. 11, no. 4, pp. 356-385
    Contributions to Journals: Articles

  • Are individual or group interventions more effective for long-term weight loss in adults with obesity?: A systematic review

    Street, S., Avenell, A.
    Clinical Obesity, vol. 12, no. 5, e12539
    Contributions to Journals: Articles

  • Procrastination and inconsistency: expressions of concern for publications with compromised integrity

    Grey, A., Avenell, A., Bolland, M. J.
    Accountability in Research
    Contributions to Journals: Articles

  • Leucine and perindopril to improve physical performance in people over 70 years with sarcopenia: the LACE factorial RCT

    Witham, M. D., Adamson, S., Avenell, A., Band, M. M., Bashir, T., Donnan, P. T., George, J., Hapca, A., Hume, C., Kemp, P., McKenzie, E., Pilvinyte, K., Rossios, C., Smith, K., Struthers, A. D., Sumukadas, D.
    Efficacy and Mechanism Evaluation, vol. 9, no. 8
    Contributions to Journals: Articles

  • Effectiveness and cost-effectiveness of text messages with or without endowment incentives for weight management in men with obesity (Game of Stones): study protocol for a randomised controlled trial

    Macaulay, L., O’Dolan, C., Avenell, A., Carroll, P., Cotton, S., Dombrowski, S., Elders, A., Goulao, B., Gray, C., Harris, F. M., Hunt, K., Kee, F., MacLennan, G., McDonald, M. D., McKinley, M., Skinner, R., Torrens, C., Tod, M., Turner, K., van der Pol, M., Hoddinott, P.
    Trials, vol. 23, no. 1, 582
    Contributions to Journals: Articles

  • A Systematic Review Examining Socioeconomic Factors in Trials of Interventions for Men that Report Weight as an Outcome

    Mcdonald, M. D., Hunt, K., Sivaramakrishnan, H., Moullin, J., Avenell, A., Kerr, D. A., Birch, J. M., Ntoumanis, N., Quested, E.
    Obesity Reviews, vol. 23, no. 7, e13436
    Contributions to Journals: Articles

  • Does weight management research for adults with severe obesity represent them? Analysis of systematic review data

    Robertson, C., Aceves-Martins, M., Cruickshank, M., Imamura, M., Avenell, A.
    BMJ Open, vol. 12, no. 5, e054459
    Contributions to Journals: Articles

  • Effect of perindopril or leucine on physical performance in older people with sarcopenia: the LACE randomized controlled trial

    Achison, M., Adamson, S., Akpan, A., Aspray, T., Avenell, A., Band, M. M., Bashir, T., Burton, L. A., Cvoro, V., Donnan, P. T., Duncan, G. W., George, J., Gordon, A. L., Gregson, C. L., Hapca, A., Henderson, E., Hume, C., Jackson, T. A., Kemp, P., Kerr, S., Kilgour, A., Lyell, V., Masud, T., McKenzie, A., McKenzie, E., Patel, H., Pilvinyte, K., Roberts, H. C., Rossios, C., Sayer, A. A., Smith, K. T., Soiza, R. L., Steves, C. J., Struthers, A. D., Sumukadas, D., Tiwari, D., Whitney, J., Witham, M. D., LACE study group
    Journal of Cachexia, Sarcopenia and Muscle, vol. 13, no. 2, pp. 858-871
    Contributions to Journals: Articles

  • Conversations about financial hardship should not be off limits

    Douglas, F. C., Avenell, A., Mohamed, S.
    BMJ (Clinical research ed.), vol. 376, o577
    Contributions to Journals: Letters

  • EFFECT OF LEUCINE SUPPLEMENTATION ON PHYSICAL PERFORMANCE, MUSCLE MASS AND QUALITY OF LIFE IN OLDER PEOPLE WITH SARCOPENIA

    Witham, M. D., Adamson, S., Avenell, A., Band, M. M., Donnan, P. T., George, J., Hapca, A., Hume, C., Kemp, P., McKenzie, E., Pilvinyte, K., Smith, K., Struthers, A. D., Sumukadas, D., LACE Study Grp
    Age and Ageing, vol. 51, no. S1, 667
    Contributions to Journals: Abstracts

  • EFFECT OF PERINDOPRIL ON PHYSICAL PERFORMANCE, MUSCLE MASS AND QUALITY OF LIFE IN OLDER PEOPLE WITH SARCOPENIA: RESULTS: FROM THE

    Witham, M. D., Adamson, S., Avenell, A., Band, M. M., Donnan, P. T., George, J., Hapca, A., Hume, C., Kemp, P., McKenzie, E., Pilvinyte, K., Smith, K., Struthers, A. D., Sumukadas, D., LACE Study Grp
    Age and Ageing, vol. 51, no. S1, 666
    Contributions to Journals: Abstracts

  • Timeliness and content of retraction notices for publications by a single research group

    Grey, A., Avenell, A., Bolland, M.
    Accountability in Research, vol. 29, no. 6, pp. 347-378
    Contributions to Journals: Articles

  • Citation of retracted publications: A challenging problem

    Bolland, M. J., Grey, A., Avenell, A.
    Accountability in Research, vol. 29, no. 1, pp. 18-25
    Contributions to Journals: Articles

  • The effectiveness of weight-loss lifestyle interventions for improving fertility in women and men with overweight or obesity and infertility: A systematic review update of evidence from randomized controlled trials

    Hunter, E., Avenell, A., Maheshwari, A., Stadler, G., Best, D.
    Obesity Reviews, vol. 22, no. 12, e13325
    Contributions to Journals: Review articles
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