Systematic reviews of selected nutritional supplementation interventions

Systematic reviews of selected nutritional supplementation interventions

A series of systematic reviews are being undertaken, including for the Cochrane Collaboration, on the effects of nutritional supplementation on people at risk of undernutrition and obesity. Topics include vitamin D supplementation and the prevention of osteoporotic fractures, protein and energy supplementation in older people including those with hip fracture, and fish oil supplementation in critical care.

Contacts

Status

Ongoing - Data Collection

Publications

Bolland MJ, Avenell A, Grey A, Gamble GD. Vitamin D and acute respiratory infection: secondary analysis of a previous randomised controlled trial and updated meta-analyses. medRxiv 2022: https://www.medrxiv.org/content/10.1101/2022.02.03.22270409v1

Bolland MJ, Avenell A, Smith K, Witham MD, Grey A. Vitamin D supplementation and testing in the UK: costly but ineffective? BMJ 2021;372:n484. 

Bolland MJ, Grey A, Avenell A. Assessment of research waste part 2: wrong study populations- an exemplar of baseline vitamin D status of participants in trials of vitamin D supplementation. BMC Med Res Methodol 2018;18:101. 

Bolland MJ, Avenell A, Grey A. Assessment of research waste part 1: an exemplar from examining study design, surrogate and clinical endpoints in studies of calcium intake and vitamin D supplementation. BMC Med Res Methodol 2018;18:103. 

Bolland MJ, Grey A, Avenell A. Effects of vitamin D supplementation on musculoskeletal health: systematic review, meta-analyses, and trial-sequential analyses. Lancet Diabetes and Endocrinology 2018; 6: 847-858. 

Avenell A, Smith TO, Curtain JP, Mak JCS, Myint PK. Nutritional supplementation for hip fracture aftercare in older people. Cochrane Database of Systematic Reviews 2016, Issue 11. Art. No.: CD001880. DOI: 10.1002/14651858.CD001880.pub6. 

Avenell A, Mak JCS, O’Connell D. Vitamin D and vitamin D analogues for preventing fractures in postmenopausal women and older men. Cochrane Database of Systematic Reviews 2014, Issue 4. Art. No.: CD000227. DOI: 10.1002/14651858.CD000227.pub4. 

Metcalfe EL, Avenell A, Fraser A. The role of branched chain amino acid (BCAA) supplementation in adults with cirrhosis and porto-systemic encephalopathy (PSE): systematic review and meta-analyses. Clinical Nutrition 2014: http://dx.doi.org/10.1016/j.clnu.2014.02.011 

Palmer AJ, Ho C, Ajibola O, Avenell A. The role of ω-3 fatty acid supplemented parenteral nutrition in critical illness in adults: a systematic review & meta-analysis. Crit Care Medicine 2013; 41(1):307-316.

Koretz RL, Avenell A, Lipman TO. Nutritional support for liver disease. Cochrane Database of Systematic Reviews 2012, Issue 2. Art. No.: CD008344. DOI: 10.1002/14651858.CD008344

Avenell A, Handoll HHG. Nutritional supplementation for hip fracture aftercare in older people. Cochrane Database of Systematic Reviews 2010, Issue 1.

Milne AC, Potter J, Vivanti A, Avenell A. Protein and energy supplementation in elderly people at risk from malnutrition (update). The Cochrane Database of Systematic Reviews 2009, Issue 2.

Avenell A. Current evidence and ongoing trials on the use of glutamine in critically ill and surgical patients. Proc Nutr Soc 2009; 68: 261-8.

Crowther M, Avenell A, Culligan DJ. A systematic review and meta-analysis of the data for glutamine supplementation in haematopoietic stem cell transplantation. Bone Marrow Transplantation 2009; 44: 413-25.

Avenell A, Gillespie WJ, Gillespie LD, O'Connell DL. Vitamin D and vitamin D analogues for preventing fractures associated with involutional and post-menopausal osteoporosis (third update). The Cochrane Database of Systematic Reviews 2009, Issue 1.