Clinical Chair in Health Services Research
- About
-
- Email Address
- a.avenell@abdn.ac.uk
- Telephone Number
- +44 (0)1224 438164
- Office Address
Health Services Research Unit
3rd Floor Health Sciences Building
Foresterhill
Aberdeen
AB25 2ZD- School/Department
- School of Medicine, Medical Sciences and Nutrition
Biography
Alison Avenell joined the Unit in 1998, as a Clinical Research Fellow. She was subsequently funded by the Chief Scientist Office (CSO) of the Scottish Government Health Directorates as a Clinical Research Fellow to undertake research in the MRC funded RECORD trial, which examined the effect of calcium and/or vitamin D supplementation in the secondary prevention of osteoporotic fractures. She also led the MAVIS trial which examined the effectiveness of vitamin and mineral supplementation in preventing infections in older people, and helped lead the SIGNET trial of glutamine and selenium supplementation in critical illness. She was a CSO funded Career Scientist and currently has a clinical chair in health services research and is an Honorary Consultant in Clinical Biochemistry, undertaking systematic reviews and randomised controlled trials of treatments for adult obesity, and under-nutrition in clinical practice.
- Research
-
Current Research
Current projects
- Evaluating the behavioural intervention, organisational and health economic evidence base for adult obesity management
- REBALANCE
- Systematic reviews of selected nutritional supplementation interventions
Completed projects
- Publications
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Gaining pounds by losing pounds: HERU Policy Brief
Working Papers: Working PapersSystematic review of the clinical and cost effectiveness of cholecystectomy versus observation/conservative management for uncomplicated symptomatic gallstones or cholecystitis
Surgical Endoscopy, vol. 29, no. 3, pp. 637-647Contributions to Journals: Articles- [ONLINE] DOI: https://doi.org/10.1007/s00464-014-3712-6
- [OPEN ACCESS] http://aura.abdn.ac.uk/bitstream/2164/5579/1/Brazzelli_2014.pdf
- [ONLINE] https://abdn.pure.elsevier.com/en/en/researchoutput/systematic-review-of-the-clinical-and-cost-effectiveness-of-cholecystectomy-versus-observationconservative-management-for-uncomplicated-symptomatic-gallstones-or-cholecystitis(e29a0a7a-469c-40f1-ad6f-8ca6e5c92211).html
Calcium supplements increase risk of myocardial infarction
Journal of Bone and Mineral Research, vol. 30, no. 2, pp. 389-390Contributions to Journals: Letters- [ONLINE] DOI: https://doi.org/10.1002/jbmr.2357
Branched-chain amino acid supplementation in adults with cirrhosis and porto-systemic encephalopathy: systematic review
Clinical Nutrition, vol. 33, no. 6, pp. 958-965Contributions to Journals: Articles- [ONLINE] DOI: https://doi.org/10.1016/j.clnu.2014.02.011
Cardiovascular disease and vitamin D supplementation: trial analysis, systematic review, and meta-analysis
The American Journal of Clinical Nutrition, vol. 100, no. 3, pp. 746-755Contributions to Journals: Articles- [ONLINE] DOI: https://doi.org/10.3945/ajcn.113.082602
- [OPEN ACCESS] http://aura.abdn.ac.uk/bitstream/2164/15632/1/Ford_2014.pdf
Clinical effectiveness and cost-effectiveness of cholecystectomy compared with observation/conservative management for preventing recurrent symptoms and complications in adults presenting with uncomplicated symptomatic gallstones or cholecystitis: a systematic review and economic evaluation
Health Technology Assessment, vol. 18, no. 55, pp. 1-102Contributions to Journals: Articles- [ONLINE] DOI: https://doi.org/10.3310/hta18550
- [OPEN ACCESS] http://aura.abdn.ac.uk/bitstream/2164/4180/1/Brazzelli_2014.pdf
Are men difficult to find?: Identifying male-specific studies in MEDLINE and Embase
Systematic reviews , vol. 3, 78Contributions to Journals: Articles- [ONLINE] DOI: https://doi.org/10.1186/2046-4053-3-78
- [OPEN ACCESS] http://aura.abdn.ac.uk/bitstream/2164/3715/1/Stewart_2014.pdf
Long term maintenance of weight loss with non-surgical interventions in obese adults: systematic review and meta-analyses of randomised controlled trials
BMJ, vol. 348, g2646Contributions to Journals: Articles- [ONLINE] DOI: https://doi.org/10.1136/bmj.g2646
- [OPEN ACCESS] http://aura.abdn.ac.uk/bitstream/2164/4181/1/Dombrowski_2014.pdf
Systematic reviews of and integrated report on the quantitative, qualitative and economic evidence base for the management of obesity in men
Health Technology Assessment, vol. 18, no. 35, pp. v-vi, xxiii-xxix, 1-424Contributions to Journals: Articles- [ONLINE] DOI: https://doi.org/10.3310/hta18350
- [OPEN ACCESS] http://aura.abdn.ac.uk/bitstream/2164/3329/1/Robertson_2014.pdf
Vitamin D and vitamin D analogues for preventing fractures in post-menopausal women and older men
Cochrane Database of Systematic Reviews, no. 4, CD000227Contributions to Journals: Articles- [ONLINE] DOI: https://doi.org/10.1002/14651858.CD000227.pub4
Patterns of weight change in the first 5 years after diagnosis of Type 2 diabetes and their impact on glycaemic control and mortality
Diabetic Medicine, vol. 31, no. s1, pp. 25-25Contributions to Journals: AbstractsSystematic review and meta-analysis of the sero-epidemiological association between Epstein-Barr virus and systemic lupus erythematosus
Arthritis Research & Therapy, vol. 16, no. 1, R3Contributions to Journals: Articles- [ONLINE] DOI: https://doi.org/10.1186/ar4429
- [OPEN ACCESS] http://aura.abdn.ac.uk/bitstream/2164/5476/1/ar4429.pdf
Advance telephone calls ahead of reminder questionnaires increase response rate in non-responders compared to questionnaire reminders only: The RECORD phone trial
Trials, vol. 15, 13Contributions to Journals: Articles- [ONLINE] DOI: https://doi.org/10.1186/1745-6215-15-13
- [OPEN ACCESS] http://aura.abdn.ac.uk/bitstream/2164/3092/1/MacLennan_2013.pdf
Calcium supplements and cancer risk: a meta-analysis of randomised controlled trials
British Journal of Nutrition, vol. 110, no. 8, pp. 1384-1393Contributions to Journals: Articles- [ONLINE] DOI: https://doi.org/10.1017/S0007114513001050
- [OPEN ACCESS] http://aura.abdn.ac.uk/bitstream/2164/3207/1/Bristow_2013.pdf
What is the appropriate MHRA regulatory response to calcium's increased cardiovascular risk?
BMJ (Clinical research ed.), vol. 346, no. 7910, pp. 1-1Contributions to Journals: Letters- [ONLINE] DOI: https://doi.org/10.1136/bmj.f3413
- [ONLINE] View publication in Scopus
Systematic review and meta-analysis of the sero-epidemiological association between Epstein Barr virus and multiple sclerosis
PloS ONE, vol. 8, no. 4, e61110Contributions to Journals: Articles- [ONLINE] DOI: https://doi.org/10.1371/journal.pone.0061110
- [OPEN ACCESS] http://aura.abdn.ac.uk/bitstream/2164/3605/1/Systematic_review.pdf
The role of ω-3 fatty acid supplemented parenteral nutrition in critical illness in adults: a systematic review and meta-analysis
Critical Care Medicine, vol. 41, no. 1, pp. 307-316Contributions to Journals: Articles- [ONLINE] DOI: https://doi.org/10.1097/CCM.0b013e3182657578
Vitamin D with calcium reduces mortality: patient level pooled analysis of 70,528 patients from eight major vitamin D trials
Journal of Clinical Endocrinology and Metabolism, vol. 97, no. 8, pp. 2670-2681Contributions to Journals: Articles- [ONLINE] DOI: https://doi.org/10.1210/jc.2011-3328
- [OPEN ACCESS] http://aura.abdn.ac.uk/bitstream/2164/2847/1/Rejnmark_2012.pdf
Nutritional support for liver disease
Cochrane Database of Systematic Reviews, no. 5, CD008344Contributions to Journals: Articles- [ONLINE] DOI: https://doi.org/10.1002/14651858.CD008344.pub2
Long-term follow-up for mortality and cancer in a randomized placebo-controlled trial of vitamin D3 and/or calcium (RECORD trial)
Journal of Clinical Endocrinology and Metabolism, vol. 97, no. 2, pp. 614-622Contributions to Journals: Articles- [ONLINE] DOI: https://doi.org/10.1210/jc.2011-1309
- [OPEN ACCESS] http://aura.abdn.ac.uk/bitstream/2164/2671/1/Avenell_2011.pdf
Identifying active ingredients in complex behavioural interventions for obese adults with obesity-related co-morbidities or additional risk factors for co-morbidities: a systematic review
Health Psychology Review, vol. 6, no. 1, pp. 7-32Contributions to Journals: Articles- [ONLINE] DOI: https://doi.org/10.1080/17437199.2010.513298
- [OPEN ACCESS] http://aura.abdn.ac.uk/bitstream/2164/2808/1/Dombrowski_2010.pdf
Lightening the load?: A systematic review of weight management interventions in the community pharmacy setting
Obesity Reviews, vol. 12, no. 11, pp. 897-911Contributions to Journals: Articles- [ONLINE] DOI: https://doi.org/10.1111/j.1467-789X.2011.00913.x
Randomised controlled feasibility trial of an evidence-informed behavioural intervention for obese adults with additional risk factors
PloS ONE, vol. 6, no. 8, e23040Contributions to Journals: Articles- [ONLINE] DOI: https://doi.org/10.1371/journal.pone.0023040
- [OPEN ACCESS] http://aura.abdn.ac.uk/bitstream/2164/2187/1/Sniehotta_2011.pdf
Calcium, vitamin D, and risk: Authors' reply
BMJ, vol. 342, no. 7810, d3544Contributions to Journals: Letters- [ONLINE] DOI: https://doi.org/10.1136/bmj.d3544
- [ONLINE] View publication in Scopus
Cardiovascular effects of calcium supplementation
Osteoporosis International, vol. 22, no. 6, pp. 1649-1658Contributions to Journals: Literature Reviews- [ONLINE] DOI: https://doi.org/10.1007/s00198-011-1599-9
- [OPEN ACCESS] http://aura.abdn.ac.uk/bitstream/2164/2492/1/Reid_2011.pdf
Further use for the harvest plot: a novel method for quantitative and qualitative data synthesis
Research Synthesis Methods, vol. 2, no. 2, pp. 79-83Contributions to Journals: Articles- [ONLINE] DOI: https://doi.org/10.1002/jrsm.37
Calcium supplements with or without vitamin D and risk of cardiovascular events: reanalysis of the Women's Health Initiative limited access dataset and meta-analysis
British Medical Journal, vol. 342, no. -, d2040Contributions to Journals: Articles- [ONLINE] DOI: https://doi.org/10.1136/bmj.d2040
- [OPEN ACCESS] http://aura.abdn.ac.uk/bitstream/2164/2060/1/Bolland_2011.pdf
Randomised trial of glutamine, selenium, or both, to supplement parenteral nutrition for critically ill patients
British Medical Journal, vol. 342, no. -, d1542Contributions to Journals: Articles- [ONLINE] DOI: https://doi.org/10.1136/bmj.d1542
- [OPEN ACCESS] http://aura.abdn.ac.uk/bitstream/2164/2321/1/Andrews_2011.pdf
Evidence-based policy on dietary calcium and vitamin D
Journal of Bone and Mineral Research, vol. 26, no. 3, pp. 452-454Contributions to Journals: Articles- [ONLINE] DOI: https://doi.org/10.1002/jbmr.327
- [OPEN ACCESS] http://aura.abdn.ac.uk/bitstream/2164/2483/1/Reid_2011.pdf
A Qualitative Study Comparing Commercial and Health Service Weight Loss Groups, Classes and Clubs
Journal of Human Nutrition and Dietetics, vol. 24, no. 1, pp. 23-31Contributions to Journals: Articles- [ONLINE] DOI: https://doi.org/10.1111/j.1365-277X.2010.01110.x
- [OPEN ACCESS] http://aura.abdn.ac.uk/bitstream/2164/2278/1/Allan_2011.pdf
Group interventions to improve health outcomes: a framework for their design and delivery
BMC Public Health, vol. 10, 800Contributions to Journals: Articles- [ONLINE] DOI: https://doi.org/10.1186/1471-2458-10-800
- [OPEN ACCESS] http://aura.abdn.ac.uk/bitstream/2164/2039/1/Hoddinott%25202010.pdf
Being underweight may reduce your ability to mobilise peripheral blood stem cells
Transfusion and Apheresis Science, vol. 43, no. 3, pp. 365-367Contributions to Journals: Articles- [ONLINE] DOI: https://doi.org/10.1016/j.transci.2010.10.010
- [ONLINE] View publication in Scopus
Calcium and heart attacks: Authors' reply
BMJ (Online), vol. 341, no. 7773, pp. 569Contributions to Journals: Letters- [ONLINE] DOI: https://doi.org/10.1136/bmj.c4998
- [ONLINE] View publication in Scopus
Effect of calcium supplements on risk of myocardial infarction and cardiovascular events: meta-analysis
British Medical Journal, vol. 341, no. -, c3691Contributions to Journals: Articles- [ONLINE] DOI: https://doi.org/10.1136/bmj.c3691
- [OPEN ACCESS] http://aura.abdn.ac.uk/bitstream/2164/756/1/Bolland%25202010.pdf
A case-control study of vitamin D status and asthma in adults
Allergy, vol. 65, no. 5, pp. 666-667Contributions to Journals: Editorials- [ONLINE] DOI: https://doi.org/10.1111/j.1398-9995.2009.02220.x
Interventions to achieve long-term weight loss in obese older people
Age and Ageing, vol. 39, no. 2, pp. 176-184Contributions to Journals: Articles- [ONLINE] DOI: https://doi.org/10.1093/ageing/afp251
- [OPEN ACCESS] http://aura.abdn.ac.uk/bitstream/2164/1401/1/Whitham%25202010.pdf
The fate of conference abstracts: systematic review and meta-analysis of surgical treatments for men with benign prostatic enlargement
World Journal of Urology, vol. 28, no. 1, pp. 63-69Contributions to Journals: Articles- [ONLINE] DOI: https://doi.org/10.1007/s00345-009-0500-3
Patient level pooled analysis of 68 500 patients from seven major vitamin D fracture trials in US and Europe
British Medical Journal, vol. 340, no. -, b5463Contributions to Journals: Articles- [ONLINE] DOI: https://doi.org/10.1136/bmj.b5463
- [OPEN ACCESS] http://aura.abdn.ac.uk/bitstream/2164/789/1/Abrahamsen%25202010.pdf
Factors Influencing the Participation of Older People in Clinical Trials: Data Analysis from the MAVIS Trial
Journal of Nutrition, Health & Aging, vol. 14, no. 1, pp. 51-56Contributions to Journals: Articles- [ONLINE] DOI: https://doi.org/10.1007/s12603-010-0009-x
- [OPEN ACCESS] http://aura.abdn.ac.uk/bitstream/2164/2036/1/Fearn%25202010.pdf
Behavioural Interventions for Obese Adults with Additional Risk Factors for Morbidity: Systematic Review of Effects on Behaviour, Weight and Disease Risk Factors
Obesity Facts, vol. 3, no. 6, pp. 377-396Contributions to Journals: Articles- [ONLINE] DOI: https://doi.org/10.1159/000323076
- [OPEN ACCESS] http://aura.abdn.ac.uk/bitstream/2164/1228/1/Dombrowski%25202010.pdf
Systematic review of long-term lifestyle interventions to prevent weight gain and morbidity in adults
Obesity Reviews, vol. 10, no. 6, pp. 627-638Contributions to Journals: Articles- [ONLINE] DOI: https://doi.org/10.1111/j.1467-789X.2009.00641.x
- [OPEN ACCESS] http://aura.abdn.ac.uk/bitstream/2164/781/1/Brown%25202009.pdf
Systematic review and meta-analyses of studies of glutamine supplementation in haematopoietic stem cell transplantation
Bone Marrow Transplantation, vol. 44, no. 7, pp. 413-425Contributions to Journals: Articles- [ONLINE] DOI: https://doi.org/10.1038/bmt.2009.41
Vitamin D supplementation and type 2 diabetes: a substudy of a randomised placebo-controlled trial in older people (RECORD trial, ISRCTN 51647438)
Age and Ageing, vol. 38, no. 5, pp. 606-609Contributions to Journals: Articles- [ONLINE] DOI: https://doi.org/10.1093/ageing/afp109
Symposium 4: Hot topics in parenteral nutrition Current evidence and ongoing trials on the use of glutamine in critically-ill patients and patients undergoing surgery
Proceedings of the Nutrition Society, vol. 68, no. 3, pp. 261-268Contributions to Journals: Articles- [ONLINE] DOI: https://doi.org/10.1017/S0029665109001372
- [OPEN ACCESS] http://aura.abdn.ac.uk/bitstream/2164/752/1/Avenell%25202009.pdf
A case of apples and pears?
Blood, vol. 113, no. 24, pp. 6259-6260Contributions to Journals: Letters- [ONLINE] DOI: https://doi.org/10.1182/blood-2009-03-211169
Vitamin D and vitamin D analogues for preventing fractures associated with involutional and post-menopausal osteoporosis
Cochrane Database of Systematic Reviews, no. 2, CD000227Contributions to Journals: Articles- [ONLINE] DOI: https://doi.org/10.1002/14651858.CD000227.pub3
A Systematic Review of the Effectiveness of Group versus Individual Treatments for Adult Obesity
Obesity Facts, vol. 2, no. 1, pp. 17-24Contributions to Journals: Articles- [ONLINE] DOI: https://doi.org/10.1159/000186144
Protein and energy supplementation in elderly people at risk from malnutrition
Cochrane Database of Systematic Reviews, no. 2, CD003288Contributions to Journals: Articles- [ONLINE] DOI: https://doi.org/10.1002/14651858.CD003288.pub3
Radioiodine therapy (RAI) for Graves' disease (GD) and the effect on ophthalmopathy: a systematic review
Clinical Endocrinology, vol. 69, no. 6, pp. 943-950Contributions to Journals: Articles- [ONLINE] DOI: https://doi.org/10.1111/j.1365-2265.2008.03279.x
Calcium and vitamin D for prevention of osteoporotic fractures
Lancet, vol. 370, no. 9605, pp. 2098-2099Contributions to Journals: Letters- [ONLINE] DOI: https://doi.org/10.1016/S0140-6736(07)61896-0
- [ONLINE] View publication in Scopus