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Dr Isobel Sleeman

Dr Isobel Sleeman
Dr Isobel Sleeman
Dr Isobel Sleeman

SCREDS Clinical Lecturer

About
Email Address
isobel.sleeman@abdn.ac.uk
School/Department
School of Medicine, Medical Sciences and Nutrition

Latest Publications

  • Daily Fluid Intake in People With Newly Diagnosed Parkinson’s Disease Is Reduced Compared With Controls

    Sleeman, I., MacLeod, A., Tarr, C., McGhee, C., Fyfe, C., Stewart, C., Scott, K., Myint, P., Johnstone, A.
    Parkinson’s Disease
    Contributions to Journals: Articles

  • Fast-track hospital end-of-life discharge pathway: is it actually fast? National clinical audit

    Geriatric Medicine Research Collaborative, Sleeman, I., Wilson, D.
    BMJ Supportive & Palliative Care, vol. 14, no. 1, pp. 90-93
    Contributions to Journals: Articles

  • First delirium episode in Parkinson’s disease and parkinsonism: incidence, predictors and outcomes

    Green, S., Perrott, S., McCleary, A., Sleeman, I., Maple-Grodem, J., Counsell, C., MacLeod, A.
    npj Parkinson's Disease, vol. 7, no. 1, 92
    Contributions to Journals: Articles

  • Age and frailty are independently associated with increased COVID-19 mortality and increased care needs in survivors: results of an international multi-centre study

    Welch, C., Geriatric Medicine Research Collaborative, Sleeman, I., COVID Collaborative
    Age and Ageing, vol. 50, no. 3, pp. 617-630
    Contributions to Journals: Articles

  • Parkinson's disease and patient related outcomes in stroke: A matched cohort study

    Perdomo-Lampignano, J. A., Pana, T. A., Sleeman, I., Clark, A. B., Sawanyawisuth, K., Tiamkao, S., Myint, P. K.
    Journal of Stroke and Cerebrovascular Diseases, vol. 29, no. 7, 104826
    Contributions to Journals: Articles

View My Publications

Research

Research Overview

I am currently a Clinical Lecturer in Geriatric and Internal Medicine. My research interests focus on diet and gut health in Parkinson's disease. 

Current Research

I have recently completed a pilot study, GUT-PD, which recruited people with newly diagnosed Parkinson's and controls. They underwent assessment of their motor and non-motor symptoms, disease severity, ability to swallow water, sense of taste, and their body composition. They were interviewed to determine their dietary intake, and provided a stool sample, which was analysed for stool metabolites, and micro-organisms. 

This study was generously supported by NHS Grampian Charities, and the Institutional Strategic Support Fund (locally distrubuted money, funded by the Wellcome Trust), and by the participants who kindly gave up their time. 

Past Research

I completed my PhD on the potential of stem cells and growth factors to reverse disease progression in Parkinson's disease, under the supervision of Professor Susan Duty at King's College, London. 

Since training at a doctor, I have worked with the research groups of Professor David Burn, in Newcastle, and Dr Carl Counsell, in Aberdeen. With them, I undertook clinical research, looking for factors, which might influence disease progression in Parkinson's disease, and also looking at the consequences of the disease, such as fracture and delirium. 

Collaborations

GUT-PD was carried out in collaberation with Dr Angus MacLeod and Professor Phyo Myint at the Institute of Applied Medical Sciences, and Professor Karen Scott and Professor Alex Johnstone at the Rowett Institute. 

Publications

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